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RNA-dependent_RNA_polymerase

Euk-Vir

Tianjin_totivirus

RNA-dependent_RNA_polymerase__YP_005454251__Tianjin_totivirus__1163537

Identity

Accession:: YP_005454251 ↗
Protein ID:: RNA-dependent_RNA_polymerase
Kingdom:: euk

Quality

90.1 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Chrymotiviricetes› Ghabrivirales› Orthototiviridae› Tianjin_totivirus

TaxID: 1163537

Cluster

View cluster (10 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 10-79

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009256209__Golden_shiner_totivirus__1856030__D1-63

D2 high residues 87-234_262-350

PDB

Domain cluster: rep: hypothetical_protein_2__YP_009336713__Beihai_toti-like_virus_4__1922734__D167-187_213-323_360-427

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2r7rA05	1.10.357.80	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.71	52.0	5.93e-01	92.8%	100.0%
3l1nA02	1.20.1280.140	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.58	22.0	3.76e-01	70.0%	97.7%
3ddhA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.54	20.0	3.43e-01	86.1%	100.0%
3eabE00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.50	21.0	3.26e-01	75.1%	100.0%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3877925	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.70	66.0	5.57e-01	100.0%	70.1%
3258406	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.70	66.0	4.90e-01	100.0%	55.0%
3983816	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.68	50.0	4.98e-01	75.1%	72.4%
3615272	304.48.1.25 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4	0.65	57.0	4.82e-01	92.4%	64.2%
3598902	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.65	57.0	4.79e-01	91.6%	64.5%
4361688	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.64	61.0	5.15e-01	100.0%	77.9%
3792091	304.48.1.25 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4	0.64	56.0	4.88e-01	91.6%	64.3%
4995948	601.1.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin	0.62	21.0	3.20e-01	75.5%	70.0%
3482980	4957.2.1.0 ↗	a+b complex topology › helical domain in yeast RNA-polymerases	0.54	31.0	3.94e-01	94.1%	95.6%
3372282	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.51	17.0	2.97e-01	93.2%	88.7%
3931851	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.50	35.0	3.42e-01	99.2%	63.4%

D3 medium residues 514-580_619-644

PDB

Domain cluster: representative