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RNA-dependent_RNA_polymerase

Euk-Vir

Red_clover_cryptic_virus_2

RNA-dependent_RNA_polymerase__YP_007889823__Red_clover_cryptic_virus_2__1323524

Identity

Accession:
YP_007889823 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

76.1 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Duplopiviricetes› Durnavirales› Partitiviridae› Betapartitivirus› Red_clover_cryptic_virus_2

TaxID: 1323524

Cluster

View cluster (450 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 588-687
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4b6iA00 1.20.120.1620 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 39.0 3.96e-01 81.0% 56.0%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 45.0 4.71e-01 88.0% 77.8%
3zibC00 1.20.120.1620 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 38.0 3.93e-01 81.0% 61.5%
2r5sA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 43.0 4.55e-01 95.0% 80.7%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.60 49.0 4.65e-01 88.0% 76.7%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.57 51.0 5.01e-01 99.0% 99.1%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.57 46.0 4.09e-01 93.0% 60.7%
4qmhA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 41.0 3.21e-01 96.0% 33.5%
4o6mA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.56 42.0 3.40e-01 84.0% 41.5%
3cqcA00 1.20.190.50 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.55 49.0 3.70e-01 99.0% 87.4%
1iq0A03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.55 42.0 4.00e-01 80.0% 75.0%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.54 43.0 3.96e-01 87.0% 72.9%
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.54 41.0 4.13e-01 96.0% 79.0%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.53 39.0 3.77e-01 78.0% 70.1%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 41.0 4.00e-01 84.0% 94.5%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.51 38.0 3.72e-01 81.0% 70.4%
2ctqA01 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.50 33.0 3.41e-01 79.0% 71.3%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4949691 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 54.0 4.49e-01 96.0% 47.1%
3857096 109.4.1.97 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2,TPR_12 0.64 47.0 3.46e-01 93.0% 30.4%
4969867 109.2.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid 0.63 55.0 3.81e-01 100.0% 34.9%
3841317 605.1.1.337 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › TRP_2 0.63 45.0 4.32e-01 76.0% 74.2%
3933426 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 44.0 4.53e-01 96.0% 77.9%
4184643 109.4.1.228 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C 0.60 44.0 3.49e-01 78.0% 71.6%
3515234 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.60 52.0 4.56e-01 97.0% 64.1%
3571073 633.12.1.11 ↗ alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › TRP_2 0.60 46.0 4.73e-01 82.0% 93.7%
3262272 101.1.10.6 ↗ alpha arrays › HTH › HTH › Cyclin-like › RB_A 0.59 45.0 3.46e-01 81.0% 87.1%
3777171 3755.3.1.44 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › JMY 0.58 48.0 3.46e-01 91.0% 50.3%
3731571 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 49.0 3.97e-01 95.0% 49.2%
4192699 603.5.1.1 ↗ alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.56 43.0 3.94e-01 80.0% 73.1%
3702681 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 47.0 3.43e-01 100.0% 34.7%
3482689 603.2.1.0 ↗ alpha bundles › STAT-like › STAT › STAT 0.54 45.0 3.92e-01 92.0% 72.5%
4975367 2500.1.1.4 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › DUF711 0.54 48.0 3.14e-01 100.0% 60.7%
3268013 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 44.0 3.50e-01 92.0% 44.5%
4215077 109.4.1.1565 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3_p135, TPR_10, TPR_12 0.53 48.0 3.13e-01 100.0% 55.2%
3717485 109.4.1.218 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP 0.53 47.0 3.22e-01 97.0% 55.3%
3226184 101.1.10.6 ↗ alpha arrays › HTH › HTH › Cyclin-like › RB_A 0.52 45.0 3.53e-01 97.0% 91.8%
3522803 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 46.0 3.56e-01 98.0% 90.7%
D2 medium residues 9-115
PDB
D3 medium residues 147-224_324-348_467-483
PDB
Domain cluster: rep: putative_RNA-dependent_RNA_polymerase__YP_003104768__Primula_malacoides_virus_China_Mar2007__479713__D102-183_314-331
D4 medium residues 225-292_349-390_429-466
PDB
Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_009177606__Rosellinia_necatrix_partitivirus_6__1573459__D215-277_292-343_369-397_431-487
D5 medium residues 391-428_484-587_708-725
PDB
Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
CATH (64)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h5xA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.84 53.0 6.18e-01 80.0% 87.1%
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.82 53.0 6.04e-01 82.5% 85.2%
2ckwA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.81 51.0 5.96e-01 80.0% 87.1%
5jxsA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.81 59.0 6.31e-01 88.7% 84.5%
1khvA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.78 54.0 5.97e-01 83.1% 86.9%
1s48A04 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.78 46.0 5.46e-01 84.4% 84.7%
1in0A01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.77 36.0 5.21e-01 73.8% 100.0%
1bqnA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.75 41.0 5.22e-01 80.0% 90.4%
1cc8A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.74 35.0 4.98e-01 77.5% 98.6%
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 49.0 5.21e-01 88.7% 75.7%
4dezA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 40.0 4.93e-01 78.8% 84.8%
1qupA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 32.0 4.60e-01 74.4% 92.9%
7uinD01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.70 57.0 5.61e-01 86.9% 81.4%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.70 39.0 5.09e-01 74.4% 97.8%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.70 37.0 3.72e-01 76.9% 49.7%
2dt9A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 36.0 4.93e-01 75.0% 100.0%
2a10D00 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.69 39.0 4.80e-01 85.6% 86.3%
3s1tA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 36.0 4.94e-01 73.8% 100.0%
2hiyA01 3.30.70.1280 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SP0830-like domains 0.69 39.0 5.08e-01 86.9% 100.0%
3dfeA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 36.0 4.77e-01 77.5% 95.1%
2djwA01 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.69 34.0 4.74e-01 75.0% 100.0%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.68 36.0 4.70e-01 75.6% 94.1%
3u5eU00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.68 40.0 4.95e-01 75.0% 93.0%
2vd3A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 31.0 4.47e-01 76.2% 94.6%
2crlA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 32.0 4.52e-01 76.9% 100.0%
2ahoB03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.67 38.0 4.96e-01 71.9% 100.0%
1nh8A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 30.0 4.34e-01 74.4% 100.0%
3mgjA00 3.30.70.2690 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › LOR/SDH bifunctional enzyme, conserved domain 0.64 37.0 4.63e-01 75.6% 93.8%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 37.0 4.55e-01 83.7% 90.3%
2hiyA02 3.30.70.1260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › bacterial protein sp0830 like 0.63 35.0 4.42e-01 88.7% 92.4%
1q8kA03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.63 40.0 4.63e-01 86.3% 88.8%
2disA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 34.0 4.45e-01 74.4% 100.0%
4g6vB00 3.30.70.2920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 38.0 4.58e-01 77.5% 94.2%
6d9mA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 48.0 4.96e-01 83.1% 86.1%
3b82A06 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 31.0 3.47e-01 76.2% 60.3%
2rilA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 36.0 4.46e-01 83.1% 95.8%
6eibD00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 47.0 4.83e-01 83.7% 82.1%
1t0tV02 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.60 38.0 4.46e-01 76.9% 90.1%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 47.0 4.55e-01 81.2% 77.5%
5xgbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.60 47.0 4.54e-01 83.7% 72.6%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.60 47.0 4.95e-01 83.1% 90.3%
5ao2B02 3.30.70.2760 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 34.0 4.36e-01 73.1% 100.0%
3pjxA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.60 46.0 4.45e-01 83.1% 71.3%
2exuA02 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.59 34.0 4.20e-01 85.6% 93.5%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.59 46.0 4.75e-01 83.7% 86.6%
2ifxA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 34.0 4.24e-01 75.6% 100.0%
1uxyA01 3.90.78.10 Alpha Beta › Alpha-Beta Complex › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 › UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 0.58 40.0 4.42e-01 76.9% 88.7%
3bf4A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 36.0 4.38e-01 75.0% 100.0%
3bn7A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 37.0 4.41e-01 76.2% 100.0%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 34.0 4.17e-01 82.5% 97.9%
2l9dA00 3.30.70.2340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF12112 family, DUF3579 0.56 32.0 3.80e-01 80.0% 82.4%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.55 31.0 3.79e-01 71.2% 90.4%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.54 27.0 3.78e-01 81.9% 97.4%
8gf5C01 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 40.0 4.24e-01 75.6% 97.9%
2cg8B02 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.54 42.0 4.56e-01 85.6% 97.0%
4cyuA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.54 44.0 4.55e-01 86.9% 94.2%
1ybtB00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.53 45.0 4.38e-01 88.7% 89.5%
1y10B02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.53 44.0 4.25e-01 88.7% 92.9%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.53 44.0 4.19e-01 88.7% 85.0%
1mg7A01 3.30.70.1000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Switch protein XOL-1, GHMP-like 0.52 40.0 3.95e-01 80.6% 83.4%
2wp4B00 3.90.1170.40 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Molybdopterin biosynthesis MoaE subunit 0.52 33.0 3.62e-01 70.6% 76.5%
1p5dX04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.51 31.0 3.77e-01 73.1% 100.0%
2c5sA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.51 42.0 4.12e-01 85.6% 91.7%
2omdA00 3.90.1170.40 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Molybdopterin biosynthesis MoaE subunit 0.51 33.0 3.57e-01 71.2% 77.0%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1875037 304.48.1.8 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.82 61.0 4.47e-01 76.2% 40.3%
3193439 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.77 64.0 5.14e-01 88.1% 67.3%
4940473 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.75 43.0 5.50e-01 79.4% 98.9%
3960648 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 62.0 4.98e-01 88.7% 64.3%
4872037 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 61.0 5.05e-01 85.6% 53.8%
3945039 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 4.81e-01 88.1% 57.0%
4004424 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 4.66e-01 88.7% 54.9%
3479534 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 4.50e-01 88.7% 48.8%
3236725 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 5.20e-01 88.7% 70.8%
5029718 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 4.77e-01 88.7% 50.9%
4516798 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 61.0 4.37e-01 88.7% 40.2%
4071235 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 61.0 4.25e-01 88.7% 46.1%
3589612 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.72 54.0 4.22e-01 77.5% 53.6%
3989356 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.72 60.0 5.75e-01 88.1% 86.5%
4937067 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.72 59.0 4.94e-01 86.3% 55.5%
3679386 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.72 60.0 4.61e-01 88.7% 50.6%
4859811 304.48.1.7 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 0.72 58.0 4.12e-01 84.4% 43.0%
4297402 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.72 59.0 4.60e-01 86.3% 66.5%
4289835 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.71 59.0 5.32e-01 86.3% 95.2%
None — 0.71 60.0 4.73e-01 88.7% 56.2%
3939572 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.71 59.0 5.23e-01 87.5% 84.9%
3645796 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.71 58.0 4.66e-01 85.6% 58.3%
3834374 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.71 59.0 4.38e-01 88.7% 43.3%
5002351 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 59.0 4.44e-01 88.7% 44.3%
4486052 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.70 59.0 4.57e-01 88.7% 65.9%
3927049 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 57.0 4.18e-01 85.0% 45.6%
3446024 304.48.1.70 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Intron_maturas2 0.70 59.0 4.10e-01 89.4% 68.5%
4442725 4967.1.1.25 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.70 59.0 4.18e-01 88.7% 50.9%
1827765 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 59.0 4.75e-01 88.7% 55.8%
4241274 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.70 59.0 4.25e-01 88.7% 47.3%
4037822 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.70 59.0 4.23e-01 88.7% 52.6%
4635290 4967.1.1.25 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.70 58.0 4.22e-01 88.7% 49.3%
3304359 304.48.1.70 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Intron_maturas2 0.70 58.0 4.05e-01 88.7% 42.2%
4361292 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 58.0 4.13e-01 88.7% 49.1%
3806425 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 61.0 4.61e-01 93.8% 61.6%
4088089 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.69 57.0 4.57e-01 87.5% 61.3%
None — 0.69 54.0 4.29e-01 81.9% 61.3%
4449545 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.69 58.0 4.40e-01 88.1% 64.2%
4434853 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 55.0 4.78e-01 83.7% 57.9%
4779977 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 38.0 4.93e-01 83.7% 100.0%
4037710 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.69 53.0 4.24e-01 80.0% 60.0%
3826004 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.68 54.0 4.21e-01 83.1% 57.4%
1411401 304.48.1.7 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 0.68 52.0 3.63e-01 78.1% 42.4%
5030091 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.68 38.0 4.95e-01 74.4% 100.0%
4223395 4967.1.1.25 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.68 57.0 4.19e-01 88.7% 47.3%
4552467 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.68 57.0 4.42e-01 88.7% 56.2%
4666185 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.68 57.0 4.17e-01 88.7% 48.9%
4544858 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.68 57.0 4.07e-01 88.7% 49.6%
2995051 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 51.0 3.91e-01 78.1% 58.0%
3353681 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.67 50.0 4.82e-01 76.9% 80.0%
4296079 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.67 50.0 3.91e-01 77.5% 57.0%
4170997 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.66 51.0 4.66e-01 79.4% 78.0%
3974782 304.28.1.1 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.66 40.0 4.94e-01 77.5% 98.9%
4128436 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.66 53.0 4.23e-01 84.4% 61.3%
3929261 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.65 53.0 4.45e-01 88.7% 52.7%
3571315 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.65 54.0 4.72e-01 88.1% 60.4%
3334380 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 56.0 4.24e-01 93.1% 58.9%
4588604 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 4.09e-01 79.4% 47.4%
4497954 304.48.1.73 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N 0.64 52.0 4.17e-01 86.3% 50.0%
4287147 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 48.0 4.13e-01 78.8% 50.6%
3934730 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.64 50.0 4.28e-01 87.5% 53.1%
3934202 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.63 52.0 5.48e-01 88.1% 96.6%
4643231 304.48.1.39 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.63 48.0 3.87e-01 78.1% 64.7%
1893002 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.63 53.0 4.48e-01 88.1% 55.9%
4248251 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 47.0 3.99e-01 78.1% 56.3%
1186663 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.63 52.0 4.54e-01 88.7% 59.8%
4033553 304.26.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP 0.62 38.0 4.63e-01 84.4% 93.3%
3939219 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.62 50.0 4.19e-01 87.5% 50.9%
3654976 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.62 52.0 4.06e-01 88.7% 58.5%
5039708 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 44.0 4.04e-01 86.3% 57.4%
4995741 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.60 47.0 4.91e-01 81.2% 93.1%
5044372 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.60 38.0 4.46e-01 80.6% 91.8%
412326 304.48.1.14 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.60 46.0 4.45e-01 83.1% 71.3%
3278063 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.59 43.0 4.32e-01 83.7% 73.8%
3613455 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.59 45.0 4.84e-01 81.2% 92.8%
4029069 304.106.1.1 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein PH1602 › Hypothetical protein PH1602 › RtcB 0.59 49.0 3.60e-01 88.7% 82.9%
4869676 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 46.0 4.13e-01 86.3% 61.2%
5035757 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.58 35.0 4.16e-01 81.2% 90.5%
2084828 304.165.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › Ta1207 0.56 45.0 4.63e-01 84.4% 100.0%
5018198 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.56 42.0 3.79e-01 82.5% 56.8%
3485236 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.56 45.0 4.80e-01 86.3% 100.0%
5579 306.8.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like › Peptidase_Prp 0.55 31.0 3.79e-01 71.2% 90.4%
4928347 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.55 45.0 4.39e-01 87.5% 94.9%
4274344 5104.1.1.0 ↗ a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.55 33.0 3.64e-01 70.0% 74.2%
5058023 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.54 45.0 4.41e-01 88.7% 96.1%
4990550 304.1.1.0 ↗ a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain 0.54 36.0 4.28e-01 86.3% 100.0%
3591785 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.53 44.0 4.53e-01 87.5% 98.0%
5225 304.1.1.2 ↗ a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › Xol-1_GHMP-like 0.51 42.0 4.02e-01 87.5% 84.5%
4112996 304.1.1.1 ↗ a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C 0.51 40.0 4.28e-01 85.0% 96.3%
3612606 304.20.1.0 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.51 34.0 4.07e-01 75.0% 100.0%
4012455 304.4.1.11 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › EthD 0.51 40.0 4.24e-01 85.6% 95.0%