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RNA-dependent_RNA_polymerase

Euk-Vir

Camponotus_yamaokai_virus

RNA-dependent_RNA_polymerase__YP_009143313__Camponotus_yamaokai_virus__1608533

Identity

Accession:
YP_009143313 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

86.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-55
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.77 59.0 5.32e-01 85.5% 64.1%
7zmgL01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 51.0 4.57e-01 78.2% 66.3%
5dckA00 1.10.1200.30 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Retrovirus capsid C-terminal domain 0.70 57.0 5.24e-01 94.5% 69.0%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.70 61.0 4.92e-01 100.0% 89.8%
2f2bA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.70 61.0 3.99e-01 100.0% 69.8%
2gslF00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.68 56.0 4.27e-01 90.9% 63.8%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.68 56.0 4.10e-01 96.4% 95.0%
1aueB00 1.20.120.150 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain 0.66 49.0 4.17e-01 81.8% 100.0%
2f3oA00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.64 55.0 3.06e-01 100.0% 62.0%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.63 49.0 4.30e-01 92.7% 55.8%
1kfwA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.63 52.0 3.17e-01 94.5% 56.5%
6f7hA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.61 51.0 3.40e-01 100.0% 69.3%
4e6hA00 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 52.0 3.02e-01 98.2% 13.4%
2np9A01 1.20.58.1300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 49.0 3.74e-01 90.9% 80.6%
1f14A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 47.0 3.23e-01 87.3% 24.0%
1wtjB01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.59 45.0 3.86e-01 87.3% 75.3%
1q2lA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.58 47.0 3.28e-01 100.0% 53.5%
1q0rA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 41.0 2.61e-01 78.2% 61.3%
1cf7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 44.0 3.98e-01 94.5% 73.2%
1wpbG01 1.10.287.680 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.54 39.0 4.02e-01 81.8% 79.6%
1cbyA00 3.40.198.10 Alpha Beta › 3-Layer(aba) Sandwich › Delta-endotoxin CytB › Delta-endotoxin CytB-like 0.53 40.0 2.84e-01 90.9% 45.8%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.52 43.0 3.83e-01 98.2% 78.8%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5002330 205.1.1.33 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_10 0.70 60.0 4.38e-01 96.4% 41.3%
3248743 3277.2.1.1 alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C 0.68 59.0 4.99e-01 100.0% 89.5%
3727634 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 55.0 5.13e-01 90.9% 87.1%
3219907 109.4.1.80 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRN3 0.67 52.0 3.25e-01 85.5% 33.8%
3678192 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.63 52.0 3.88e-01 94.5% 64.7%
3498094 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.61 44.0 4.00e-01 81.8% 56.5%
3598098 3652.1.1.0 alpha duplicates or obligate multimers › Qua1 › Qua1 › Qua1 0.55 39.0 4.05e-01 78.2% 82.0%
3928148 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 46.0 2.99e-01 100.0% 72.0%
D2 medium residues 65-88_109-211_245-299
PDB
D3 medium residues 89-108_212-244_300-380
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 28.9 8.10e-07 67.9% 16.1%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.83 64.0 6.75e-01 80.6% 100.0%
6qwtA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.80 64.0 6.34e-01 84.3% 90.1%
5jxsA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.78 63.0 6.22e-01 84.3% 90.1%
1ra6A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.78 56.0 6.29e-01 74.6% 100.0%
3h5xA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.77 59.0 6.30e-01 79.9% 100.0%
1jwwA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 43.0 5.42e-01 70.1% 100.0%
1hi8A03 3.30.70.1600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 59.0 5.38e-01 88.1% 89.8%
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.70 60.0 5.85e-01 100.0% 85.4%
4pwuC00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 40.0 5.10e-01 70.1% 98.7%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 43.0 5.26e-01 70.1% 97.7%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.66 48.0 3.47e-01 75.4% 79.3%
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.65 38.0 4.77e-01 70.1% 98.7%
1r89A03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.65 48.0 4.89e-01 77.6% 94.8%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 49.0 4.84e-01 79.9% 95.8%
4iobA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 51.0 4.79e-01 83.6% 98.1%
3hvaA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 52.0 4.93e-01 87.3% 89.5%
6pwjA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 53.0 4.95e-01 88.8% 95.2%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 49.0 4.75e-01 82.1% 88.6%
3mtkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 51.0 4.78e-01 88.1% 92.0%
3fotA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.60 42.0 3.50e-01 72.4% 84.5%
6i0y501 3.30.70.1730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain 0.60 46.0 4.67e-01 79.9% 93.8%
4zmuA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.58 50.0 4.76e-01 91.8% 90.3%
1gpjA01 3.30.460.30 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain 0.57 39.0 3.87e-01 70.9% 89.7%
4hvmB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.57 40.0 3.60e-01 72.4% 87.8%
5abxA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.57 48.0 4.48e-01 94.0% 77.5%
6fh1B01 3.30.590.10 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain 0.57 39.0 3.29e-01 70.9% 81.1%
4nx9A02 2.60.40.4390 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 39.0 4.14e-01 71.6% 95.0%
1tr0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 38.0 4.20e-01 70.9% 97.2%
4v19J00 3.30.70.1730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain 0.55 39.0 3.66e-01 73.9% 64.3%
5xzqF00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 37.0 4.18e-01 70.1% 100.0%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3983816 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 5.01e-01 88.8% 75.2%
4882532 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 61.0 4.49e-01 87.3% 60.4%
135026 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.72 43.0 5.42e-01 70.1% 100.0%
4012107 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.70 42.0 5.23e-01 70.1% 98.8%
4956865 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.68 51.0 4.54e-01 79.1% 90.2%
4215083 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.67 49.0 5.00e-01 75.4% 92.3%
4952279 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.66 48.0 4.36e-01 73.9% 96.6%
3961033 304.154.1.1 a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain › GGDEF_2 0.66 49.0 4.63e-01 76.9% 80.0%
3386169 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.66 45.0 3.87e-01 70.1% 93.5%
4066041 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.65 45.0 3.80e-01 70.1% 88.6%
4429067 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 51.0 4.71e-01 82.8% 91.2%
4936768 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.65 48.0 4.39e-01 76.9% 96.0%
4932448 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.65 43.0 5.08e-01 70.1% 100.0%
3937461 304.151.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase 0.64 44.0 4.83e-01 70.1% 92.7%
3800768 304.20.1.1 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP_RNA-bind 0.64 46.0 4.52e-01 73.9% 95.9%
3511024 304.28.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.63 44.0 4.94e-01 70.9% 98.0%
3605466 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.63 44.0 3.76e-01 72.4% 57.7%
3286133 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.63 52.0 4.90e-01 88.1% 87.5%
3214695 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.62 40.0 4.79e-01 70.1% 97.8%
139439 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.62 51.0 4.78e-01 88.1% 92.0%
1186663 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.62 56.0 4.63e-01 100.0% 95.4%
5041003 304.8.1.4 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.61 35.0 4.49e-01 70.1% 97.4%
3408002 304.8.1.49 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › R1_ABCA1 0.61 41.0 4.47e-01 70.9% 82.7%
4101583 304.60.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10 0.61 43.0 4.07e-01 73.9% 68.5%
4319667 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.60 42.0 3.95e-01 72.4% 88.2%
4216153 304.60.1.8 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10, PF27436 0.60 43.0 3.98e-01 73.9% 65.9%
3193678 304.60.1.9 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › PF28227 0.60 43.0 3.53e-01 73.9% 72.0%
4589463 304.8.1.62 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › CitX 0.60 45.0 4.09e-01 78.4% 73.3%
4446001 304.60.1.8 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10, PF27436 0.59 42.0 3.94e-01 73.9% 65.9%
4088995 304.60.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10 0.59 42.0 3.95e-01 73.9% 66.7%
3410191 304.60.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10 0.58 42.0 3.58e-01 73.9% 50.7%
3171897 304.60.1.10 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10, PF28227 0.58 42.0 3.88e-01 73.9% 74.7%
4490700 304.60.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10 0.58 42.0 3.89e-01 73.9% 66.3%
4163325 304.60.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10 0.58 41.0 3.95e-01 73.9% 69.4%
3787075 304.60.1.10 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10, PF28227 0.58 41.0 3.71e-01 73.9% 67.4%
3768588 304.8.1.54 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_13 0.57 40.0 4.41e-01 71.6% 90.5%
4015638 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.57 45.0 3.69e-01 84.3% 82.0%
3987417 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.56 40.0 3.07e-01 72.4% 69.6%
3839711 2004.1.1.221 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › P-loop_TraG 0.54 47.0 2.94e-01 94.0% 36.3%
3869277 331.18.1.0 a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc 0.53 39.0 3.55e-01 76.9% 89.7%
1235054 304.4.1.9 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Chlor_dismutase 0.51 38.0 3.88e-01 76.1% 79.8%