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RNA-dependent_RNA_polymerase

Euk-Vir

Le_Blanc_nodavirus

RNA-dependent_RNA_polymerase__YP_009175040__Le_Blanc_nodavirus__1241918

Identity

Accession:: YP_009175040 ↗
Protein ID:: RNA-dependent_RNA_polymerase
Kingdom:: euk

Quality

56.7 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Magsaviricetes› Nodamuvirales› Nodaviridae› Le_Blanc_nodavirus

TaxID: 1241918

Cluster

View cluster (17 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 11-115

PDB

D2 medium residues 335-380_407-487_529-585

PDB

Domain cluster: rep: hypothetical_protein_3__YP_009345007__Wuhan_spider_virus_8__1923757__D1-105_147-200

ECOD (24)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1279063	304.48.1.13 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5	0.83	78.0	5.74e-01	99.5%	67.3%
5364	304.48.1.8 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1	0.79	74.0	5.66e-01	98.9%	73.1%
217141	304.48.1.15 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3	0.77	72.0	5.67e-01	98.9%	73.4%
3928801	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.75	59.0	4.72e-01	82.1%	70.3%
4108146	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.73	53.0	4.26e-01	75.0%	59.1%
4071235	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.73	53.0	3.81e-01	75.0%	37.0%
3939319	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.72	58.0	4.47e-01	83.7%	67.6%
3382764	626.1.1.0 ↗	alpha complex topology › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain)	0.72	52.0	3.47e-01	75.0%	30.1%
3945039	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.71	52.0	4.25e-01	75.0%	56.7%
3927049	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.70	62.0	4.71e-01	94.6%	65.6%
3265091	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.70	62.0	4.33e-01	95.1%	48.7%
3451410	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.69	61.0	4.50e-01	94.6%	58.5%
3792091	304.48.1.25 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4	0.68	50.0	4.03e-01	75.0%	53.9%
3918122	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.68	60.0	4.62e-01	94.6%	64.8%
3784946	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.67	61.0	4.61e-01	96.2%	66.0%
3241316	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.66	59.0	4.83e-01	95.7%	74.0%
4361688	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.66	60.0	4.68e-01	96.2%	69.1%
4937067	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.64	47.0	4.15e-01	75.0%	65.7%
5029718	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.63	46.0	3.76e-01	75.0%	58.5%
3574984	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.63	58.0	4.52e-01	98.4%	67.2%
3997418	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.62	56.0	4.55e-01	96.7%	65.7%
3473558	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.61	51.0	4.78e-01	90.2%	100.0%
4872037	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.61	44.0	3.90e-01	75.0%	66.9%
3454701	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.59	43.0	3.70e-01	73.9%	57.1%

D3 medium residues 674-805

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2xgsB01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.57	32.0	4.27e-01	74.2%	100.0%
2gruA02	1.20.1090.10	Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain	0.50	37.0	3.31e-01	78.0%	86.8%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3683342	109.4.1.629 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF629	0.50	41.0	2.98e-01	87.9%	85.9%