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RNA-dependent_RNA_polymerase

Euk-Vir

Ustilaginoidea_virens_RNA_virus_5

RNA-dependent_RNA_polymerase__YP_009182167__Ustilaginoidea_virens_RNA_virus_5__1756615

Identity

Accession:
YP_009182167 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

90.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-119
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3i3nA02 1.25.40.420 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 39.0 4.07e-01 81.4% 68.9%
2pkeA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 37.0 4.26e-01 90.3% 98.7%
2qkmB01 1.10.10.1050 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Dcp2, box A domain 0.52 41.0 4.32e-01 85.8% 100.0%
1itkA01 1.10.520.10 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › 0.51 39.0 3.68e-01 84.1% 95.8%
4bl7B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 36.0 3.69e-01 82.3% 78.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5048002 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.54 39.0 3.70e-01 74.3% 83.7%
3090480 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.54 46.0 3.65e-01 93.8% 50.0%
3959950 2006.1.1.44 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like 0.53 45.0 3.79e-01 93.8% 62.0%
5075946 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.52 43.0 3.42e-01 92.9% 52.7%
D2 medium residues 142-313_596-640
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 49.8 3.70e-13 78.3% 33.8%
D3 medium residues 314-442_458-509
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 117.2 1.30e-33 100.0% 41.9%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mukA02 3.90.1850.10 Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 0.73 67.0 4.82e-01 100.0% 48.4%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3454701 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 48.0 4.13e-01 70.2% 57.5%
4516798 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 64.0 4.69e-01 100.0% 45.7%
3615272 304.48.1.25 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 0.66 61.0 4.72e-01 100.0% 54.8%
3598902 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 60.0 4.69e-01 100.0% 55.5%
3960648 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 59.0 4.91e-01 100.0% 64.6%
3792091 304.48.1.25 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 0.60 55.0 4.43e-01 100.0% 54.5%
4296494 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 47.0 3.97e-01 85.1% 57.0%
5081699 186.1.1.4 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 0.54 26.0 3.58e-01 87.3% 91.1%
3920672 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 25.0 3.52e-01 77.3% 91.1%
3684015 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 29.0 3.81e-01 82.3% 98.0%
3921728 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 29.0 3.63e-01 82.3% 90.4%
D4 medium residues 443-457_510-595
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 96.2 3.30e-27 85.2% 17.6%
D5 medium residues 641-692_745-778_824-860
PDB
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3732507 2008.1.1.143 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF7924 0.55 39.0 2.96e-01 73.2% 90.2%
3812094 5.1.4.223 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RIC1_2nd 0.50 44.0 3.23e-01 100.0% 73.4%
D6 medium residues 693-744
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g36B00 1.20.890.10 Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 0.64 45.0 4.58e-01 82.7% 72.5%
4xjvA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 42.0 2.95e-01 92.3% 98.6%
2n7zA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.55 43.0 3.52e-01 90.4% 94.3%
2jfrA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.54 40.0 2.70e-01 86.5% 21.4%
2dbfA01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 37.0 3.34e-01 90.4% 97.8%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3256214 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.57 39.0 2.71e-01 71.2% 21.1%
4994269 101.1.2.673 alpha arrays › HTH › HTH › winged helix domain › HTH_HVO_0163_N 0.54 37.0 3.28e-01 75.0% 74.1%
3531043 110.1.1.2 alpha arrays › DEATH domain › DEATH domain › DEATH domain › CARD 0.53 41.0 3.52e-01 92.3% 76.8%