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RNA-dependent_RNA_polymerase

Euk-Vir

Fusarium_poae_mitovirus_1

RNA-dependent_RNA_polymerase__YP_009272898__Fusarium_poae_mitovirus_1__1848150

Identity

Accession:: YP_009272898 ↗
Protein ID:: RNA-dependent_RNA_polymerase
Kingdom:: euk

Quality

71.2 mean pLDDT

Taxonomy

Orthornavirae› Lenarviricota› Howeltoviricetes› Cryppavirales› Mitoviridae› Unuamitovirus› Fusarium_poae_mitovirus_1

TaxID: 1848150

Cluster

View cluster (26 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-109

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009465715__Erysiphe_necator_mitovirus_1__2052561__D5-113

D2 medium residues 110-135_152-273_314-351

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009259482__Cronartium_ribicola_mitovirus_3__1816486__D153-243_260-277

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF05919.17 best	Mitovir_RNA_pol	73.9	1.90e-20	63.4%	24.3%

D3 medium residues 136-151_274-313_352-442

PDB

Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF05919.17 best	Mitovir_RNA_pol	167.7	7.00e-49	62.6%	18.3%
PF05919.17	Mitovir_RNA_pol	49.2	6.00e-13	33.3%	9.5%

D4 medium residues 443-503

PDB

Domain cluster: representative

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4e0aA00	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.58	40.0	2.97e-01	72.1%	30.1%
7a0hA01	3.30.1140.60	Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit	0.57	39.0	3.38e-01	78.7%	44.6%
2hqyA01	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.56	38.0	3.04e-01	77.0%	33.1%
6b4rA01	3.40.605.10	Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1	0.53	38.0	2.58e-01	80.3%	61.0%
2w00A02	3.90.640.50	Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 ›	0.53	35.0	3.37e-01	70.5%	57.5%
1x3kA01	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.53	39.0	3.07e-01	83.6%	45.6%
3bz6A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.52	39.0	3.69e-01	85.2%	82.1%
3g7uA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	34.0	2.47e-01	70.5%	36.1%

ECOD (26)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3927465	101.1.2.309 ↗	alpha arrays › HTH › HTH › winged helix domain › GPAT_C	0.61	46.0	3.04e-01	83.6%	23.2%
3740646	1128.1.1.0 ↗	alpha bundles › LYR protein › LYR protein › LYR protein	0.60	47.0	4.35e-01	88.5%	81.2%
3963900	3018.1.1.1 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › TilS	0.60	43.0	3.89e-01	77.0%	64.7%
3392896	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.60	46.0	4.25e-01	88.5%	77.6%
3538243	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.59	47.0	4.35e-01	90.2%	72.5%
4316271	3018.1.1.0 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like	0.59	42.0	3.91e-01	77.0%	68.8%
4159154	3018.1.1.0 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like	0.58	42.0	3.80e-01	77.0%	60.0%
5073218	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.58	44.0	3.94e-01	83.6%	58.9%
4055950	3018.1.1.0 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like	0.58	41.0	4.01e-01	78.7%	67.1%
3537242	101.1.2.34 ↗	alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding	0.57	43.0	3.69e-01	82.0%	67.0%
3605770	4099.1.1.0 ↗	a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like	0.57	41.0	2.86e-01	80.3%	50.6%
3541293	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.56	42.0	3.82e-01	85.2%	76.7%
4609020	101.1.2.642 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF3631	0.55	41.0	3.72e-01	83.6%	78.9%
4975486	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.55	46.0	3.14e-01	100.0%	48.5%
3952422	101.1.2.642 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF3631	0.55	41.0	3.71e-01	83.6%	80.0%
3734132	3542.1.1.3 ↗	alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B	0.54	38.0	2.47e-01	75.4%	78.7%
5057127	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.54	38.0	2.54e-01	75.4%	19.6%
3800966	109.20.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Coatomer subunit alpha C-terminal domain › Coatomer subunit alpha C-terminal domain	0.53	44.0	3.02e-01	98.4%	51.6%
2097968	101.1.2.4 ↗	alpha arrays › HTH › HTH › winged helix domain › Forkhead	0.52	42.0	3.90e-01	95.1%	80.5%
1318715	243.16.1.1 ↗	a+b two layers › Cystatin-like › hypothetical protein CLOLEP_02462 › hypothetical protein CLOLEP_02462 › DUF6836	0.51	39.0	3.27e-01	85.2%	63.2%
3898745	101.1.2.34 ↗	alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding	0.51	44.0	3.88e-01	100.0%	75.8%
3453690	4326.1.1.1 ↗	a+b two layers › ERH-like › ERH-like › ERH-like › ER	0.51	43.0	3.82e-01	98.4%	73.7%
4945161	2484.1.1.2 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin	0.51	39.0	2.86e-01	86.9%	94.2%
4590814	3949.1.1.1 ↗	alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT	0.51	32.0	3.19e-01	70.5%	58.5%
3889374	207.1.1.0 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats	0.50	34.0	2.27e-01	75.4%	51.9%
4028295	2004.1.1.73 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1	0.50	39.0	2.76e-01	86.9%	34.3%

D5 medium residues 509-678

PDB