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RNA-dependent_RNA_polymerase

Euk-Vir

Fusarium_poae_mitovirus_2

RNA-dependent_RNA_polymerase__YP_009272899__Fusarium_poae_mitovirus_2__1848151

Identity

Accession:
YP_009272899 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

71.4 mean pLDDT

Taxonomy

Orthornavirae› Lenarviricota› Howeltoviricetes› Cryppavirales› Mitoviridae› Unuamitovirus› Fusarium_poae_mitovirus_2

TaxID: 1848151

Cluster

View cluster (26 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 32-160
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009465715__Erysiphe_necator_mitovirus_1__2052561__D5-113
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6ks6a01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.69 60.0 4.62e-01 93.8% 92.4%
3p9dE01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.68 57.0 4.50e-01 89.9% 91.3%
6ks6Z01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.68 59.0 4.62e-01 93.8% 94.4%
5x9vA01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.68 59.0 4.72e-01 93.8% 99.2%
6ks6q01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.66 57.0 4.49e-01 93.8% 91.9%
7vwtA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.66 47.0 3.53e-01 72.9% 48.6%
4hxiB03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.62 32.0 3.64e-01 79.1% 63.6%
3floB00 1.10.3200.20 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › DNA Polymerase alpha, zinc finger 0.59 41.0 3.65e-01 70.5% 72.8%
2x3mA00 1.25.40.670 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 36.0 3.31e-01 86.0% 47.6%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.58 32.0 3.47e-01 79.1% 62.7%
4fb2A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.56 48.0 3.47e-01 96.1% 68.4%
3dewA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 38.0 3.75e-01 72.9% 67.1%
3ccyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 37.0 3.62e-01 72.9% 62.6%
5cbgA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 33.0 3.64e-01 95.3% 77.5%
1hk3A03 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.53 36.0 4.08e-01 82.9% 95.7%
6kkiA01 1.20.1720.10 Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D 0.53 42.0 3.06e-01 83.7% 91.1%
5kbwB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.52 44.0 4.06e-01 93.8% 96.5%
3owaA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 32.0 3.12e-01 79.8% 55.8%
1fc3B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 38.0 4.18e-01 85.3% 99.0%
3vkgA09 1.20.920.30 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.51 38.0 3.74e-01 79.1% 94.4%
2vvwA00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.51 35.0 3.37e-01 95.3% 60.7%
4iduB01 1.20.142.20 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › 0.50 39.0 4.02e-01 85.3% 88.2%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4934465 593.1.1.1 ↗ alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 0.69 60.0 4.74e-01 93.8% 95.8%
4950248 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.66 36.0 4.18e-01 79.1% 72.6%
5051792 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.58 33.0 3.72e-01 82.9% 71.0%
3722134 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 34.0 3.00e-01 78.3% 37.9%
3253573 593.1.1.0 ↗ alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like 0.57 48.0 3.75e-01 89.9% 94.0%
3411504 148.1.3.179 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_BCS1 0.56 29.0 3.92e-01 87.6% 100.0%
5010916 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.56 37.0 3.70e-01 79.1% 64.4%
3904691 141.1.1.2 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › SQS_PSY 0.54 45.0 3.44e-01 88.4% 56.5%
4015726 141.1.1.0 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases 0.54 44.0 3.21e-01 87.6% 53.3%
3207535 141.1.1.2 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › SQS_PSY 0.53 44.0 3.25e-01 88.4% 57.8%
5073580 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.53 38.0 3.96e-01 85.3% 81.7%
4457628 1075.5.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.53 45.0 3.61e-01 94.6% 84.4%
4943503 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.52 34.0 3.69e-01 88.4% 82.0%
5064398 101.1.10.3 ↗ alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.51 32.0 3.58e-01 85.3% 80.0%
3974315 180.1.1.1 ↗ alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 0.51 44.0 3.70e-01 93.0% 60.5%
4931675 180.1.1.1 ↗ alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 0.51 42.0 3.71e-01 90.7% 66.2%
3545309 150.1.1.79 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Piezo_TM1-24 0.51 44.0 4.44e-01 98.4% 93.8%
4979232 3930.1.1.0 ↗ alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.50 45.0 4.48e-01 97.7% 96.3%
D2 medium residues 161-305_339-388
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009259482__Cronartium_ribicola_mitovirus_3__1816486__D153-243_260-277
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 87.2 1.80e-24 56.4% 23.7%
PF05919.17 Mitovir_RNA_pol 57.6 1.70e-15 26.7% 9.9%
D3 medium residues 306-338_389-486
PDB
Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 167.1 1.00e-48 74.8% 19.5%
PF05919.17 Mitovir_RNA_pol 29.0 8.20e-07 25.2% 6.6%