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RNA-dependent_RNA_polymerase
Euk-VirFusarium_poae_mitovirus_4
RNA-dependent_RNA_polymerase__YP_009272901__Fusarium_poae_mitovirus_4__1848153
Identity
- Accession:
- YP_009272901 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
71.1
mean pLDDT
Taxonomy
Orthornavirae›
Lenarviricota›
Howeltoviricetes›
Cryppavirales›
Mitoviridae›
Duamitovirus›
Fusarium_poae_mitovirus_4
TaxID: 1848153
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 141-174_283-299_385-408
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 26.8 | 3.60e-06 | 34.7% | 4.2% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.59 | 38.0 | 3.74e-01 | 81.3% | 61.7% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.57 | 35.0 | 3.25e-01 | 74.7% | 47.9% |
| 2damA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.55 | 37.0 | 3.88e-01 | 96.0% | 76.1% |
| 2ltuA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.52 | 37.0 | 3.96e-01 | 92.0% | 91.9% |
| 2wh5A00 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.50 | 40.0 | 3.78e-01 | 86.7% | 96.7% |
ECOD (2)
D2
medium
residues 175-282_343-384
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 37.7 | 1.80e-09 | 72.0% | 19.7% |
| PF05919.17 | Mitovir_RNA_pol | 47.6 | 1.90e-12 | 28.7% | 8.6% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 23.0 | 2.94e-01 | 86.7% | 63.7% |
| 1lq7A00 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.53 | 25.0 | 3.53e-01 | 82.7% | 97.0% |
| 2zw3A00 | 1.20.1440.80 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain | 0.53 | 37.0 | 3.43e-01 | 72.0% | 95.5% |
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.53 | 49.0 | 3.34e-01 | 100.0% | 49.0% |
| 3ee4A00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.50 | 41.0 | 3.33e-01 | 87.3% | 77.5% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3794379 | 3935.1.1.0 ↗ | extended segments › 4E-BP2 › 4E-BP2 › 4E-BP2 | 0.57 | 17.0 | 2.87e-01 | 71.3% | 76.0% |
| 3589612 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 52.0 | 3.93e-01 | 100.0% | 60.9% |
| 3945039 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 52.0 | 3.93e-01 | 100.0% | 62.7% |
| 4004424 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 52.0 | 3.77e-01 | 100.0% | 53.1% |
| 4461237 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.54 | 51.0 | 3.41e-01 | 100.0% | 40.4% |
| 5368 | 304.48.1.23 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_5 | 0.53 | 49.0 | 3.56e-01 | 100.0% | 63.1% |
| 4497954 | 304.48.1.73 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N | 0.52 | 49.0 | 3.79e-01 | 100.0% | 63.2% |
D3
medium
residues 300-342_409-485
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 75.9 | 4.70e-21 | 65.0% | 13.7% |
| PF05919.17 | Mitovir_RNA_pol | 53.5 | 3.10e-14 | 38.3% | 9.0% |
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7uinD01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.80 | 63.0 | 5.62e-01 | 83.3% | 94.0% |
| 4hkqA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.75 | 60.0 | 5.64e-01 | 84.2% | 83.3% |
| 5jxsA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.69 | 57.0 | 5.37e-01 | 87.5% | 98.6% |
| 1khvA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.67 | 50.0 | 4.87e-01 | 76.7% | 100.0% |
| 1s48A04 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.67 | 51.0 | 5.35e-01 | 80.0% | 100.0% |
| 1ayeA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.64 | 44.0 | 4.84e-01 | 70.8% | 85.9% |
| 1jqgA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.64 | 43.0 | 4.86e-01 | 70.8% | 90.1% |
| 2epgB00 | 3.90.1860.10 | Alpha Beta › Alpha-Beta Complex › tRNA-splicing ligase RtcB › tRNA-splicing ligase RtcB | 0.61 | 45.0 | 3.11e-01 | 78.3% | 83.5% |
| 5o60I00 | 3.30.70.1730 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain | 0.60 | 42.0 | 4.17e-01 | 71.7% | 87.3% |
| 4zmuA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.59 | 47.0 | 4.38e-01 | 85.8% | 83.9% |
| 3d68A01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.59 | 41.0 | 4.66e-01 | 71.7% | 93.5% |
| 1kwmA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.59 | 41.0 | 4.68e-01 | 72.5% | 97.7% |
| 1zpwX00 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 37.0 | 4.34e-01 | 71.7% | 92.7% |
| 1vk8A00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 39.0 | 4.29e-01 | 70.0% | 100.0% |
| 5hatA01 | 3.30.70.150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain | 0.56 | 39.0 | 3.85e-01 | 73.3% | 95.5% |
| 1vx4q01 | 3.30.70.1730 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain | 0.55 | 38.0 | 3.70e-01 | 70.0% | 89.5% |
| 4v19J00 | 3.30.70.1730 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain | 0.54 | 37.0 | 3.37e-01 | 70.0% | 63.1% |
| 2dhaA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.53 | 42.0 | 4.26e-01 | 86.7% | 92.7% |
| 4nwbA01 | 3.30.70.1730 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain | 0.51 | 41.0 | 4.01e-01 | 85.8% | 100.0% |
| 3smzA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.51 | 40.0 | 4.12e-01 | 84.2% | 94.6% |
| 3viuA04 | 3.90.650.10 | Alpha Beta › Alpha-Beta Complex › Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 › PurM-like C-terminal domain | 0.50 | 44.0 | 3.94e-01 | 97.5% | 100.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3810170 | 304.48.1.43 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mitovir_RNA_pol | 0.99 | 83.0 | 6.97e-01 | 85.8% | 99.4% |
| 3306901 | 304.48.1.43 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mitovir_RNA_pol | 0.94 | 75.0 | 6.59e-01 | 82.5% | 95.2% |
| 3336938 | 304.48.1.43 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mitovir_RNA_pol | 0.90 | 79.0 | 5.95e-01 | 90.0% | 71.2% |
| 3068775 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.83 | 66.0 | 5.44e-01 | 83.3% | 80.8% |
| 3708776 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.73 | 60.0 | 4.35e-01 | 88.3% | 75.4% |
| 3251732 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 63.0 | 4.85e-01 | 96.7% | 65.2% |
| 3390198 | 304.7.1.1 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 | 0.66 | 44.0 | 5.14e-01 | 70.0% | 96.5% |
| 5026454 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.63 | 34.0 | 4.53e-01 | 72.5% | 100.0% |
| 4568770 | 304.56.1.2 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 | 0.62 | 39.0 | 4.60e-01 | 72.5% | 90.6% |
| 4944359 | 304.56.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like | 0.61 | 39.0 | 4.59e-01 | 73.3% | 91.8% |
| 4321822 | 304.56.1.2 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 | 0.61 | 38.0 | 4.56e-01 | 70.8% | 95.0% |
| 4426624 | 304.56.1.2 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 | 0.60 | 38.0 | 4.42e-01 | 71.7% | 90.6% |
| 5046128 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.59 | 37.0 | 4.51e-01 | 72.5% | 100.0% |
| 4123628 | 304.56.1.2 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 | 0.59 | 38.0 | 4.49e-01 | 72.5% | 97.5% |
| 4936417 | 304.26.1.3 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › DUF2102 | 0.59 | 40.0 | 4.30e-01 | 73.3% | 80.0% |
| 4480482 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.59 | 40.0 | 4.23e-01 | 71.7% | 79.0% |
| 4556494 | 304.56.1.2 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 | 0.58 | 38.0 | 4.28e-01 | 72.5% | 86.0% |
| 4340559 | 304.154.1.0 ↗ | a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain | 0.57 | 46.0 | 4.67e-01 | 86.7% | 86.7% |
| 3961146 | 304.11.1.1 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Acyl_transf_1 | 0.52 | 40.0 | 3.93e-01 | 81.7% | 76.0% |