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RNA-dependent_RNA_polymerase

Euk-Vir

Fusarium_poae_mycovirus_1

RNA-dependent_RNA_polymerase__YP_009272909__Fusarium_poae_mycovirus_1__1849542

Identity

Accession:
YP_009272909 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

80.9 mean pLDDT

Cluster

View cluster (7 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 905-1043
PDB
Domain cluster: rep: VP2__YP_009665170__Eriocheir_sinensis_reovirus__273810__D721-872
D2 medium residues 25-76
PDB
D3 medium residues 81-236
PDB
D4 medium residues 237-378
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ye6A01 1.10.8.1290 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1 0.59 41.0 4.63e-01 85.2% 96.2%
2nwlC00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.53 43.0 3.19e-01 88.7% 99.0%
D5 medium residues 450-471_551-583_625-689
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009342055__Trichoderma_atroviride_mycovirus__1934322__D310-326_384-417_467-550_629-645
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u89A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 48.0 4.57e-01 75.0% 91.4%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.63 46.0 4.13e-01 76.7% 90.9%
6k6iA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 44.0 3.59e-01 72.5% 59.8%
3nzpB03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 35.0 4.27e-01 84.2% 86.1%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.60 40.0 4.05e-01 98.3% 68.9%
1kz7A01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.59 42.0 3.60e-01 72.5% 85.5%
2hs5A02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.59 41.0 3.94e-01 71.7% 66.4%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 41.0 4.05e-01 74.2% 67.7%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 35.0 4.31e-01 86.7% 100.0%
1yq3C02 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.56 34.0 3.65e-01 71.7% 67.6%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 45.0 4.39e-01 86.7% 95.6%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 34.0 4.18e-01 87.5% 98.7%
1f5nA01 1.20.1000.10 Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain 0.56 46.0 3.43e-01 98.3% 35.8%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.55 45.0 3.88e-01 87.5% 92.1%
3fhnA01 6.10.280.210 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A 0.55 39.0 3.36e-01 85.8% 47.3%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 47.0 4.44e-01 94.2% 100.0%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 34.0 3.78e-01 89.2% 81.7%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.53 36.0 3.44e-01 70.0% 99.3%
7e4gA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 39.0 3.32e-01 79.2% 64.5%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 38.0 3.73e-01 80.8% 71.4%
2w2dD01 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.51 45.0 3.11e-01 96.7% 92.6%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 35.0 4.04e-01 87.5% 100.0%
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.50 36.0 2.85e-01 73.3% 69.5%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.50 32.0 3.42e-01 94.2% 71.6%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3603229 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.69 41.0 4.80e-01 94.2% 83.5%
4027009 3636.1.1.0 ↗ a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.65 45.0 3.64e-01 70.0% 70.0%
5058790 133.2.1.1 ↗ alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C 0.63 45.0 3.89e-01 73.3% 75.1%
3180225 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 43.0 2.88e-01 74.2% 40.0%
4020741 4953.1.1.0 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.59 43.0 3.39e-01 75.0% 74.7%
3968965 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.58 38.0 4.27e-01 85.0% 86.7%
3584334 604.12.1.56 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ASTER 0.58 36.0 4.06e-01 87.5% 82.2%
3828970 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.56 39.0 4.35e-01 84.2% 89.5%
3773235 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.56 34.0 3.86e-01 75.0% 81.1%
4460528 101.11.1.1 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.56 36.0 4.06e-01 82.5% 84.2%
1145756 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 35.0 3.57e-01 88.3% 65.0%
3429338 180.1.1.7 ↗ alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2_C 0.55 43.0 3.42e-01 83.3% 77.9%
3694767 532.2.1.11 ↗ alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › Arb1 0.55 46.0 4.24e-01 90.8% 85.2%
3610330 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 44.0 3.71e-01 100.0% 51.7%
5072045 604.10.1.0 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.53 39.0 4.20e-01 87.5% 87.6%
3339567 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.52 34.0 3.01e-01 72.5% 44.4%
4294309 133.2.1.1 ↗ alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C 0.52 46.0 3.94e-01 95.8% 95.7%
3480264 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.51 37.0 4.05e-01 75.0% 97.9%
4990979 7516.1.1.51 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_21 0.50 43.0 3.07e-01 93.3% 91.9%
D6 medium residues 472-496_513-550
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4y93A03 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 40.0 3.05e-01 95.2% 56.7%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4955493 1075.1.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.56 45.0 3.15e-01 95.2% 65.3%
3659467 243.1.1.45 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › S6PP_C 0.56 46.0 3.83e-01 98.4% 70.4%
3962642 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.54 42.0 3.21e-01 87.3% 99.4%
3993228 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 43.0 3.03e-01 100.0% 65.3%
3267267 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 37.0 2.49e-01 82.5% 29.7%
3736485 323.1.1.0 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.51 36.0 2.82e-01 77.8% 53.1%
D7 medium residues 584-624_690-776
PDB
Domain cluster: rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1in0A01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.78 43.0 5.72e-01 74.2% 100.0%
1lfpA03 3.30.70.980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain 0.73 41.0 5.16e-01 79.7% 94.5%
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 64.0 6.53e-01 99.2% 96.7%
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.72 43.0 5.40e-01 82.0% 100.0%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.71 42.0 5.25e-01 82.0% 100.0%
5suhA02 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.70 42.0 4.60e-01 77.3% 73.8%
1khvA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.69 63.0 6.28e-01 97.7% 96.9%
2dy1A03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.69 40.0 5.01e-01 77.3% 96.1%
2gqqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.68 41.0 4.86e-01 76.6% 89.4%
3cgiA00 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.67 44.0 4.68e-01 85.2% 75.9%
2zbcA01 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.67 39.0 4.96e-01 73.4% 100.0%
3i4pA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.66 40.0 4.76e-01 75.8% 90.5%
1ufwA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.66 43.0 4.84e-01 78.9% 87.4%
6yiiA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 52.0 4.37e-01 82.8% 66.5%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.65 39.0 4.65e-01 74.2% 91.5%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.64 42.0 4.99e-01 80.5% 100.0%
3c19A01 3.30.70.1380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transcriptional regulatory protein pf0864 domain like 0.64 44.0 4.86e-01 80.5% 89.9%
4qu7A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 40.0 4.89e-01 77.3% 100.0%
2cyyA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.63 41.0 4.70e-01 82.0% 88.4%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.63 48.0 3.91e-01 79.7% 45.6%
2cg4A02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.63 41.0 4.86e-01 80.5% 98.8%
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 37.0 4.55e-01 71.9% 97.4%
2efpA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.62 41.0 4.63e-01 82.0% 88.8%
6vh5C03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 40.0 4.64e-01 78.9% 94.4%
2p5vA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.61 40.0 4.77e-01 85.2% 100.0%
5o5cB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.61 37.0 3.73e-01 72.7% 59.4%
1cg2A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 44.0 4.68e-01 75.8% 99.1%
1x4dA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 37.0 4.11e-01 76.6% 77.5%
2disA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 38.0 4.53e-01 74.2% 100.0%
2x7iA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.59 46.0 4.67e-01 93.0% 82.8%
1s5jA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.59 53.0 5.00e-01 100.0% 95.5%
2qrrA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 42.0 4.75e-01 87.5% 99.0%
2okqB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 45.0 4.69e-01 80.5% 91.5%
1cqmA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.58 42.0 4.69e-01 79.7% 98.0%
4gdnC00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.58 43.0 3.25e-01 78.1% 81.2%
3pyfA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.58 45.0 4.41e-01 82.0% 96.4%
3io1A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 42.0 4.41e-01 77.3% 98.3%
2hfsA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.57 44.0 4.28e-01 82.8% 100.0%
3b49A00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.56 44.0 3.77e-01 82.8% 63.2%
3b1dA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 42.0 3.49e-01 78.9% 87.6%
3gonA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.56 44.0 4.33e-01 82.8% 100.0%
2oi2A02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.55 44.0 4.42e-01 91.4% 82.8%
4uskA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.55 42.0 3.93e-01 79.7% 91.6%
3dxvA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 38.0 3.58e-01 71.1% 59.2%
6lpnA03 3.30.70.2190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 41.0 4.29e-01 79.7% 90.4%
1lc5A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 35.0 3.53e-01 71.9% 65.6%
8ffuA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.53 41.0 3.33e-01 79.7% 81.2%
1mg7A01 3.30.70.1000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Switch protein XOL-1, GHMP-like 0.53 43.0 3.95e-01 89.1% 85.1%
3ffhA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 37.0 3.68e-01 75.0% 68.2%
1qgnG01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.53 40.0 3.17e-01 79.7% 92.3%
3cllA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.52 38.0 3.08e-01 75.0% 85.5%
3op7A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 39.0 3.30e-01 78.9% 88.8%
4obuA01 3.90.1150.170 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.52 36.0 3.01e-01 71.1% 50.0%
2g5fB00 3.60.120.10 Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase 0.52 46.0 3.23e-01 100.0% 89.1%
4ritA01 3.90.1150.170 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.52 36.0 3.04e-01 71.1% 51.6%
5ijgA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 40.0 3.37e-01 82.0% 94.8%
2zbiA02 3.30.70.2120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 39.0 4.23e-01 82.8% 97.2%
2q5wE00 3.90.1170.40 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Molybdopterin biosynthesis MoaE subunit 0.50 41.0 4.01e-01 87.5% 86.9%
1gsoA04 3.90.600.10 Alpha Beta › Alpha-Beta Complex › Glycinamide Ribonucleotide Synthetase; Chain A, domain 4 › Phosphoribosylglycinamide synthetase, C-terminal domain 0.50 35.0 3.98e-01 78.9% 98.9%
4hacA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.50 40.0 4.05e-01 88.3% 85.3%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4678773 304.117.1.1 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.74 42.0 5.26e-01 79.7% 93.3%
3941725 304.28.1.3 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD-TM1 0.73 46.0 5.51e-01 80.5% 95.3%
4269228 304.122.1.1 ↗ a+b two layers › Alpha-beta plaits › Nitrogen repressor-like proteins › Nitrogen repressor-like proteins › NRD1_2 0.72 43.0 4.59e-01 78.1% 68.2%
4926794 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.72 43.0 5.07e-01 77.3% 88.2%
3708065 304.11.1.0 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.71 41.0 5.19e-01 81.2% 98.6%
4091138 304.24.1.3 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.70 44.0 5.08e-01 79.7% 87.8%
4411830 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.70 50.0 5.69e-01 85.2% 100.0%
4962129 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.69 42.0 4.80e-01 79.7% 81.1%
4971209 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.69 46.0 5.07e-01 79.7% 85.0%
4590927 304.28.1.2 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG 0.69 47.0 5.50e-01 78.9% 100.0%
5032260 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.68 41.0 5.02e-01 75.8% 96.2%
3407163 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.68 52.0 5.35e-01 78.9% 92.4%
4254800 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.68 51.0 5.69e-01 85.9% 100.0%
5074623 304.128.1.0 ↗ a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.68 40.0 4.95e-01 79.7% 97.3%
5002351 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 61.0 4.38e-01 100.0% 46.7%
5079777 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.68 41.0 4.95e-01 79.7% 96.2%
3954242 321.1.1.1 ↗ a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › Gln-synt_C 0.67 51.0 3.75e-01 79.7% 60.0%
4185082 3016.1.1.1 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.67 34.0 4.39e-01 71.9% 87.1%
4234725 304.28.1.4 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.67 47.0 5.35e-01 82.0% 98.9%
5056142 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.67 41.0 4.66e-01 79.7% 83.0%
5054271 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.67 42.0 4.71e-01 79.7% 82.7%
3947003 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.67 42.0 4.74e-01 79.7% 84.2%
4478614 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 41.0 4.80e-01 74.2% 88.6%
5065415 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.66 40.0 4.91e-01 79.7% 96.2%
3970823 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.66 44.0 5.13e-01 82.0% 96.7%
5072246 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.66 41.0 4.77e-01 82.0% 88.9%
4956754 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.66 45.0 5.11e-01 79.7% 94.7%
4105300 304.8.1.5 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NIL 0.65 47.0 5.36e-01 89.8% 100.0%
4253448 304.52.1.1 ↗ a+b two layers › Alpha-beta plaits › YbeD/HP0495-like › YbeD/HP0495-like › DUF493 0.65 40.0 4.68e-01 74.2% 88.6%
4963839 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.65 41.0 4.86e-01 78.9% 95.3%
3279536 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.65 39.0 4.55e-01 79.7% 85.6%
4933397 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.65 40.0 4.82e-01 79.7% 97.5%
4961378 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.65 41.0 4.72e-01 79.7% 90.0%
4963354 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.65 41.0 4.64e-01 78.9% 85.3%
3974171 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.65 40.0 4.67e-01 79.7% 88.9%
3719744 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.64 43.0 5.03e-01 82.0% 97.8%
4130739 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.64 40.0 4.62e-01 79.7% 88.9%
5034146 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.64 41.0 4.84e-01 82.0% 96.5%
4464525 304.8.1.8 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_4 0.64 40.0 4.77e-01 79.7% 95.3%
4991134 304.8.1.120 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › CAA_C 0.64 51.0 4.96e-01 85.9% 98.6%
5023739 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.64 46.0 5.06e-01 79.7% 92.4%
5039662 304.48.1.112 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › SatD 0.64 49.0 4.95e-01 82.8% 80.0%
3972451 304.8.1.68 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF493 0.63 40.0 4.72e-01 73.4% 92.0%
5074053 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 38.0 4.19e-01 79.7% 73.3%
4070960 304.52.1.1 ↗ a+b two layers › Alpha-beta plaits › YbeD/HP0495-like › YbeD/HP0495-like › DUF493 0.63 39.0 4.61e-01 70.3% 91.8%
3643305 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.63 53.0 5.24e-01 90.6% 97.0%
4952886 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.63 46.0 4.85e-01 82.8% 85.2%
4542099 3016.1.1.1 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.63 33.0 4.06e-01 71.9% 82.1%
3962434 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 42.0 4.79e-01 85.2% 92.6%
3288175 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.63 43.0 4.87e-01 88.3% 94.7%
3176552 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 39.0 4.00e-01 78.9% 64.0%
5063265 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.62 37.0 4.58e-01 74.2% 98.7%
5044372 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.62 46.0 4.89e-01 82.8% 89.1%
4935680 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.62 45.0 4.85e-01 82.8% 89.1%
4258900 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.62 33.0 3.92e-01 71.9% 77.1%
4950395 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.62 45.0 4.84e-01 82.8% 89.1%
4987385 304.4.1.2 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase 0.62 42.0 4.77e-01 79.7% 97.8%
3288076 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.61 41.0 4.59e-01 82.0% 91.6%
4957408 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.61 44.0 4.83e-01 82.8% 93.3%
3897632 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 40.0 4.68e-01 78.9% 100.0%
5045689 304.6.1.1 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.60 51.0 4.08e-01 93.0% 84.2%
5040415 1036.1.1.1 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.60 44.0 4.79e-01 82.0% 93.3%
139922 304.1.1.1 ↗ a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C 0.59 47.0 4.72e-01 83.6% 97.7%
3586929 304.1.1.1 ↗ a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C 0.59 46.0 4.52e-01 82.8% 100.0%
3402258 304.8.1.49 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › R1_ABCA1 0.58 43.0 4.71e-01 77.3% 99.0%
3189664 3016.1.1.3 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_5 0.58 47.0 3.24e-01 88.3% 71.3%
3947466 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.58 51.0 4.71e-01 99.2% 81.8%
3709456 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 44.0 4.33e-01 81.2% 100.0%
3595821 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 38.0 4.44e-01 76.6% 96.7%
3490902 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.55 50.0 4.70e-01 100.0% 90.0%
4031692 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.54 41.0 4.38e-01 79.7% 95.5%
3478552 304.4.1.5 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Dyp_perox_N 0.54 48.0 4.65e-01 95.3% 97.9%
4939599 325.1.2.1 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Molybdopterin synthase subunit MoaE › MoaE 0.53 39.0 4.08e-01 78.9% 89.0%
5042040 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.50 37.0 3.35e-01 75.8% 93.5%
4973708 7587.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domain in carbohydrate phosphatases › Rossmann-like domain in carbohydrate phosphatases › Rossmann-like domain in carbohydrate phosphatases › Inositol_P 0.50 32.0 3.28e-01 87.5% 64.6%
D8 medium residues 777-839
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.61 44.0 4.61e-01 82.5% 84.2%
3besR03 6.10.140.1480 Special › Helix non-globular › Helix Hairpins › 0.60 41.0 4.29e-01 87.3% 80.4%
1vp7A00 1.10.287.1040 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit 0.58 39.0 3.89e-01 87.3% 66.2%
2wyhB02 1.10.1240.90 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.57 46.0 3.93e-01 90.5% 84.0%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 45.0 4.03e-01 88.9% 79.3%
3rklA00 6.10.140.1640 Special › Helix non-globular › Helix Hairpins › 0.56 39.0 3.59e-01 71.4% 81.2%
2w00A05 1.20.58.2040 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 48.0 4.06e-01 95.2% 67.3%
2r6fA02 1.20.1580.10 Mainly Alpha › Up-down Bundle › ABC transporter ATPase like fold › ABC transporter ATPase like domain 0.53 37.0 2.91e-01 76.2% 90.3%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1789315 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.68 61.0 4.81e-01 100.0% 58.5%
4013542 301.6.1.0 ↗ a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like 0.58 48.0 3.45e-01 96.8% 73.2%
4393207 5049.1.3.1 ↗ alpha complex topology › Ammonium transporter-related › Ammonium transporter-related › Na(+)-translocating NADH-quinone reductase subunit B › NQR2_RnfD_RnfE 0.57 45.0 2.86e-01 88.9% 56.1%
3707677 4146.1.1.0 ↗ alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like 0.56 36.0 3.72e-01 87.3% 70.0%
3393157 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.55 43.0 4.59e-01 93.7% 98.2%
3930198 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.50 42.0 4.01e-01 98.4% 94.7%
D9 medium residues 840-898
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.70 53.0 3.20e-01 96.6% 13.4%
1mukA02 3.90.1850.10 Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 0.65 44.0 2.57e-01 84.7% 8.0%
4by6D02 1.25.40.800 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 47.0 3.25e-01 100.0% 66.2%
4q5eA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 30.0 2.75e-01 83.1% 42.7%
3p9aF00 1.10.132.80 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.53 37.0 2.92e-01 74.6% 67.2%
4uhiA01 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 42.0 2.65e-01 96.6% 33.6%
4nkwA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.52 42.0 2.61e-01 96.6% 32.8%
4cj0A02 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.52 37.0 2.28e-01 78.0% 39.9%
3u1nB01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.52 44.0 2.82e-01 100.0% 63.4%
5trdA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 33.0 3.00e-01 94.9% 45.2%
2nn5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 41.0 3.09e-01 94.9% 85.4%
1cksB00 3.30.170.10 Alpha Beta › 2-Layer Sandwich › Cyclin-Dependent Kinase Subunit Type 2 › Cyclin-dependent kinase, regulatory subunit 0.51 27.0 2.55e-01 89.8% 37.2%
6j95A01 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.50 42.0 2.60e-01 100.0% 50.7%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3286193 207.2.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.56 36.0 2.56e-01 79.7% 20.0%
4003744 5067.1.1.3 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched 0.55 46.0 2.61e-01 100.0% 63.5%
3272367 2004.5.1.3 ↗ a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › DENN 0.54 42.0 2.84e-01 96.6% 21.3%
3623035 2004.5.1.3 ↗ a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › DENN 0.54 38.0 2.57e-01 96.6% 18.0%
5071832 102.1.2.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase 0.52 44.0 3.11e-01 100.0% 64.3%
3942751 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.51 35.0 2.82e-01 84.7% 35.0%
4441063 102.1.2.1 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase › HhH-GPD 0.51 41.0 2.94e-01 100.0% 68.8%
D10 medium residues 1188-1293
PDB
Domain cluster: rep: putative_RNA-dependent_RNA_polymerase__YP_003288789__Fusarium_graminearum_dsRNA_mycovirus-3__687917__D1148-1239
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vzbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 48.0 4.09e-01 76.4% 58.7%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 48.0 4.19e-01 79.2% 62.9%
2c2jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 44.0 3.87e-01 78.3% 69.7%
5u9nB00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.60 45.0 4.31e-01 78.3% 87.5%
2h7oA01 1.20.120.1330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain 0.58 42.0 4.04e-01 75.5% 86.2%
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 40.0 3.61e-01 79.2% 83.2%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.54 39.0 3.31e-01 76.4% 47.3%
2qptA01 1.10.268.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › 0.54 40.0 3.64e-01 79.2% 93.2%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 31.0 3.63e-01 75.5% 82.4%
6fhpD00 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.53 32.0 3.91e-01 75.5% 100.0%
4giwB00 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.53 43.0 3.76e-01 91.5% 94.1%
2vxgA02 1.10.220.100 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › conserved c-terminal region of ge- 1 0.52 34.0 3.68e-01 71.7% 82.4%
5nl9A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 28.0 3.15e-01 75.5% 67.9%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.51 32.0 3.74e-01 82.1% 100.0%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
137165 150.1.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin 0.65 47.0 4.06e-01 76.4% 58.3%
3789429 186.1.1.1 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 0.59 37.0 3.61e-01 76.4% 55.8%
4988448 5081.1.1.1 ↗ alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.59 44.0 3.80e-01 80.2% 54.3%
3596558 633.1.1.0 ↗ alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.57 42.0 3.75e-01 78.3% 71.6%
3847082 192.17.1.27 ↗ alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › PCM1_C 0.57 44.0 4.33e-01 83.0% 82.6%
3602825 633.12.1.0 ↗ alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.56 41.0 3.83e-01 75.5% 63.8%
3414731 109.4.1.307 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2 0.56 41.0 2.63e-01 76.4% 28.4%
3775354 181.1.1.6 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › PCM1_C 0.56 43.0 4.19e-01 82.1% 79.1%
3732713 133.1.1.1 ↗ alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.55 41.0 3.19e-01 80.2% 75.9%
3508753 650.1.1.1 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.52 35.0 3.64e-01 93.4% 75.8%
3679557 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.52 36.0 4.00e-01 71.7% 92.9%
3793395 109.4.1.307 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2 0.52 40.0 2.59e-01 81.1% 90.0%
3597917 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.51 37.0 3.63e-01 74.5% 76.5%
D11 medium residues 1294-1354
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.81 52.0 5.34e-01 73.8% 69.0%
1b10A00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.80 65.0 5.41e-01 88.5% 55.8%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 49.0 4.95e-01 70.5% 72.6%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 51.0 4.80e-01 72.1% 71.8%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.73 50.0 4.48e-01 70.5% 54.9%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 50.0 4.28e-01 73.8% 51.0%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.71 56.0 3.91e-01 83.6% 59.0%
1hlvA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.71 47.0 4.77e-01 77.0% 70.0%
2nsaA00 1.10.3120.10 Mainly Alpha › Orthogonal Bundle › Trigger factor, domain 2 › Trigger factor, C-terminal domain 0.70 58.0 4.19e-01 90.2% 34.7%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.69 48.0 4.25e-01 73.8% 52.7%
4bs9A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 57.0 3.94e-01 90.2% 76.1%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 52.0 3.58e-01 80.3% 78.0%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 47.0 4.54e-01 72.1% 64.8%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 50.0 4.19e-01 77.0% 49.5%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.66 49.0 4.35e-01 91.8% 54.9%
2f48A03 1.10.10.480 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphofructokinase; domain 3 0.66 43.0 4.13e-01 70.5% 56.0%
1ulyA02 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.65 52.0 4.49e-01 98.4% 55.4%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.63 46.0 4.40e-01 77.0% 68.6%
2dodA00 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.63 43.0 3.93e-01 75.4% 53.7%
1ylmA00 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.61 51.0 3.82e-01 90.2% 49.3%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.60 48.0 4.54e-01 90.2% 100.0%
6mh4A03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.60 44.0 4.10e-01 82.0% 62.0%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.59 42.0 3.95e-01 77.0% 58.7%
3i4uA01 1.20.120.1080 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 40.0 3.40e-01 70.5% 44.3%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 50.0 3.50e-01 96.7% 57.1%
1r9dA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.55 46.0 2.61e-01 100.0% 27.5%
5b1aC01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 46.0 4.44e-01 93.4% 88.2%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5043686 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.82 73.0 4.97e-01 96.7% 31.0%
4419515 150.1.1.59 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.81 53.0 4.76e-01 72.1% 51.2%
3280651 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.76 67.0 4.48e-01 98.4% 99.6%
3630230 7004.1.1.0 ↗ 0.75 52.0 4.46e-01 88.5% 46.3%
375927 150.1.1.14 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like 0.74 54.0 4.68e-01 77.0% 60.9%
3270180 5063.1.1.0 ↗ alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.73 58.0 5.11e-01 86.9% 76.7%
4027189 589.1.1.0 ↗ alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain 0.73 60.0 5.25e-01 91.8% 61.1%
3991070 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.72 63.0 4.75e-01 100.0% 40.3%
3284117 106.1.1.11 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N 0.72 54.0 4.20e-01 82.0% 75.6%
3959087 106.1.1.0 ↗ alpha arrays › Globin-like › Globin-like › Globin-like 0.71 55.0 4.11e-01 83.6% 71.3%
4032825 7523.1.1.22 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › ABC2_membrane_3 0.71 49.0 3.78e-01 72.1% 32.6%
5055477 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.70 48.0 4.40e-01 73.8% 55.0%
3614667 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 49.0 3.01e-01 72.1% 13.0%
5069130 6026.1.1.0 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.70 53.0 5.70e-01 82.0% 100.0%
3503444 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.69 54.0 4.65e-01 82.0% 92.2%
4561057 5041.1.1.41 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › prePAAR_I 0.69 55.0 5.31e-01 95.1% 77.1%
4934293 4993.1.1.0 ↗ extended segments › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit 0.69 50.0 4.57e-01 77.0% 63.7%
4329615 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.69 48.0 4.62e-01 73.8% 68.6%
3652237 4970.1.1.0 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.68 51.0 3.97e-01 82.0% 53.6%
3628716 109.4.1.898 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_leprecan 0.68 56.0 3.44e-01 91.8% 60.0%
4175087 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.68 48.0 3.92e-01 73.8% 46.4%
5058468 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.68 54.0 5.09e-01 88.5% 76.0%
3222941 5054.1.1.59 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.68 49.0 3.50e-01 77.0% 42.7%
3174080 6169.1.1.0 ↗ extended segments › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 0.68 54.0 4.74e-01 86.9% 94.4%
3311957 1097.1.1.2 ↗ alpha bundles › C-terminal subgroup One Signature (COS) domain › C-terminal subgroup One Signature (COS) domain › C-terminal subgroup One Signature (COS) domain › PF30904 0.67 57.0 5.63e-01 95.1% 95.4%
None — 0.67 59.0 3.81e-01 100.0% 39.3%
3956535 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.66 58.0 4.33e-01 98.4% 45.2%
4136793 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.66 59.0 4.05e-01 100.0% 54.8%
3927398 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.66 55.0 4.60e-01 93.4% 58.1%
4983608 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.66 55.0 5.40e-01 95.1% 87.7%
4514462 547.1.1.1 ↗ alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.65 54.0 4.65e-01 95.1% 57.0%
1821875 4970.1.1.1 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.65 43.0 4.42e-01 70.5% 69.5%
4851577 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.64 53.0 3.75e-01 93.4% 33.8%
4944029 601.7.1.16 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN_Swt1 0.64 55.0 4.08e-01 98.4% 98.2%
3288147 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.63 53.0 4.60e-01 100.0% 66.0%
3588172 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.63 50.0 3.73e-01 86.9% 50.0%
3676919 4970.1.1.0 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.62 49.0 3.48e-01 85.2% 35.3%
3620560 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.62 50.0 3.79e-01 90.2% 60.7%
4050521 547.1.1.1 ↗ alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.61 50.0 4.33e-01 96.7% 57.3%
4993526 101.11.1.13 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › EMC6_arch 0.59 49.0 4.43e-01 96.7% 65.9%
4949711 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.58 50.0 3.77e-01 95.1% 77.2%
3987846 2002.1.1.50 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › F_bP_aldolase 0.56 45.0 2.96e-01 91.8% 90.4%
3580974 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.54 40.0 3.84e-01 82.0% 69.3%
4030532 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 44.0 3.26e-01 100.0% 78.9%