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RNA-dependent_RNA_polymerase

Euk-Vir

White_clover_mottle_virus

RNA-dependent_RNA_polymerase__YP_009315896__White_clover_mottle_virus__1913024

Identity

Accession:
YP_009315896 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

72.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 91-194
PDB
D2 medium residues 212-230_317-442
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02122.22 best Peptidase_S39 111.0 8.50e-32 74.5% 50.7%
D3 medium residues 231-316
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02122.22 best Peptidase_S39 108.1 6.30e-31 100.0% 42.4%
D4 medium residues 675-719_740-771
PDB
Domain cluster: representative
D5 medium residues 772-804_935-1026_1044-1097
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 96.1 3.50e-27 98.3% 43.7%
D6 medium residues 805-934_1027-1043
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 94.1 1.30e-26 98.0% 30.3%
D7 medium residues 1098-1178
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 51.0 4.89e-01 70.4% 58.1%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 50.0 4.78e-01 75.3% 84.4%
4iluA02 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.66 46.0 4.18e-01 74.1% 87.4%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.65 55.0 4.06e-01 96.3% 58.5%
3llwD00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.65 54.0 3.62e-01 88.9% 29.8%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 51.0 4.41e-01 88.9% 63.4%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.64 55.0 4.43e-01 95.1% 63.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 55.0 4.89e-01 96.3% 71.6%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.63 50.0 4.30e-01 86.4% 70.2%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 49.0 4.44e-01 85.2% 92.5%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 53.0 5.00e-01 96.3% 91.8%
4s2rQ03 3.90.230.10 Alpha Beta › Alpha-Beta Complex › Creatine Amidinohydrolase › Creatinase/methionine aminopeptidase superfamily 0.61 48.0 3.28e-01 86.4% 97.3%
5jqkA03 3.90.230.10 Alpha Beta › Alpha-Beta Complex › Creatine Amidinohydrolase › Creatinase/methionine aminopeptidase superfamily 0.60 46.0 3.16e-01 82.7% 98.3%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 51.0 4.52e-01 96.3% 99.2%
6jkvA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.59 42.0 3.02e-01 72.8% 52.6%
8alzB08 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.58 44.0 3.81e-01 82.7% 94.7%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 49.0 4.36e-01 93.8% 94.9%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 46.0 4.14e-01 90.1% 80.0%
3dadA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.57 49.0 3.34e-01 100.0% 44.8%
4yxtA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.55 36.0 2.92e-01 70.4% 35.5%
4h0pB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 45.0 3.38e-01 97.5% 52.2%
3ccyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 44.0 3.71e-01 95.1% 58.5%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3861871 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 49.0 4.74e-01 90.1% 66.3%
3173503 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.68 60.0 4.12e-01 100.0% 53.3%
4639996 150.7.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PE › PE › PE 0.64 44.0 4.30e-01 71.6% 78.9%
3306390 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.64 55.0 5.06e-01 96.3% 83.8%
3440537 109.4.1.91 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec10_HB 0.64 55.0 3.91e-01 100.0% 78.9%
3739447 109.46.1.1 alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH 0.62 54.0 4.56e-01 97.5% 71.4%
3890229 603.1.1.64 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › CUPID 0.62 54.0 5.11e-01 96.3% 89.5%
3923718 109.4.1.163 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N 0.59 51.0 3.02e-01 100.0% 22.7%
185553 109.4.1.80 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRN3 0.58 50.0 3.77e-01 98.8% 45.9%
3691039 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.56 40.0 4.06e-01 75.3% 80.0%
4393207 5049.1.3.1 alpha complex topology › Ammonium transporter-related › Ammonium transporter-related › Na(+)-translocating NADH-quinone reductase subunit B › NQR2_RnfD_RnfE 0.54 43.0 2.94e-01 91.4% 76.7%
3309675 226.1.1.0 a+b two layers › POZ domain › POZ domain › POZ domain 0.53 40.0 2.92e-01 82.7% 96.3%