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RNA-dependent_RNA_polymerase
Euk-VirBeihai_narna-like_virus_24
RNA-dependent_RNA_polymerase__YP_009333245__Beihai_narna-like_virus_24__1922452
Identity
- Accession:
- YP_009333245 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
81.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 455-541
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3k1rA01 | 1.20.1160.20 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › | 0.57 | 41.0 | 4.26e-01 | 95.4% | 81.5% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 39.0 | 3.31e-01 | 73.6% | 87.9% |
| 4kvmA01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 48.0 | 2.99e-01 | 97.7% | 22.5% |
| 1xriA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 43.0 | 3.63e-01 | 86.2% | 91.4% |
| 4e19A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.54 | 46.0 | 4.10e-01 | 97.7% | 80.5% |
| 5bp8A02 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.53 | 46.0 | 3.37e-01 | 100.0% | 53.5% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 42.0 | 4.04e-01 | 100.0% | 75.2% |
| 1kpsB00 | 1.25.40.200 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ran-GTPase activating protein 1, C-terminal domain | 0.52 | 45.0 | 3.82e-01 | 100.0% | 89.1% |
| 1d8cA03 | 1.20.1220.12 | Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III | 0.52 | 41.0 | 3.60e-01 | 86.2% | 91.1% |
| 7nazA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 41.0 | 2.96e-01 | 87.4% | 40.0% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3710693 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 53.0 | 3.65e-01 | 96.6% | 26.3% |
| 3221179 | 2007.2.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II | 0.55 | 47.0 | 3.67e-01 | 95.4% | 76.3% |
| 3997924 | 109.4.1.301 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Hid1 | 0.54 | 47.0 | 2.87e-01 | 98.9% | 30.4% |
| 3951455 | 109.4.1.277 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › T7SS_EccA1_N | 0.52 | 41.0 | 2.90e-01 | 87.4% | 28.4% |
| 3618077 | 603.1.1.149 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Frag1 | 0.51 | 36.0 | 3.28e-01 | 74.7% | 94.4% |
| 3905342 | 3579.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › Oxidored_q3 | 0.51 | 35.0 | 2.82e-01 | 74.7% | 36.5% |
D2
high
residues 545-702
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009342440__Wuhan_insect_virus_18__1923722__D703-884
D3
medium
residues 72-89_196-227_261-317
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.74 | 68.0 | 5.71e-01 | 100.0% | 92.6% |
| 6z74C02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.58 | 42.0 | 3.72e-01 | 76.6% | 100.0% |
| 3rc3A01 | 1.10.1740.140 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.55 | 32.0 | 3.29e-01 | 80.4% | 59.2% |
| 2w00A02 | 3.90.640.50 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › | 0.55 | 24.0 | 2.87e-01 | 78.5% | 57.5% |
| 2cwlB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 42.0 | 3.17e-01 | 82.2% | 82.7% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 40.0 | 3.65e-01 | 80.4% | 97.4% |
| 2p5kA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 27.0 | 3.33e-01 | 79.4% | 77.8% |
| 2kr7A02 | 2.40.10.330 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.53 | 21.0 | 2.73e-01 | 83.2% | 61.4% |
| 1p65A00 | 6.10.140.90 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 27.0 | 3.50e-01 | 75.7% | 93.0% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3397393 | 603.1.1.101 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_6 | 0.56 | 46.0 | 3.17e-01 | 89.7% | 79.7% |
| 3614219 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.53 | 43.0 | 3.01e-01 | 88.8% | 73.2% |
| 4990979 | 7516.1.1.51 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_21 | 0.53 | 47.0 | 3.31e-01 | 100.0% | 87.8% |
| 4043003 | 601.7.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase | 0.52 | 38.0 | 3.34e-01 | 78.5% | 58.8% |
| 5029865 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.50 | 43.0 | 3.94e-01 | 95.3% | 86.8% |
D4
medium
residues 228-260_318-415_440-452