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RNA-dependent_RNA_polymerase

Euk-Vir

Beihai_narna-like_virus_24

RNA-dependent_RNA_polymerase__YP_009333245__Beihai_narna-like_virus_24__1922452

Identity

Accession:
YP_009333245 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

81.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 455-541
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k1rA01 1.20.1160.20 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › 0.57 41.0 4.26e-01 95.4% 81.5%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 39.0 3.31e-01 73.6% 87.9%
4kvmA01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 48.0 2.99e-01 97.7% 22.5%
1xriA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.54 43.0 3.63e-01 86.2% 91.4%
4e19A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 46.0 4.10e-01 97.7% 80.5%
5bp8A02 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.53 46.0 3.37e-01 100.0% 53.5%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 42.0 4.04e-01 100.0% 75.2%
1kpsB00 1.25.40.200 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ran-GTPase activating protein 1, C-terminal domain 0.52 45.0 3.82e-01 100.0% 89.1%
1d8cA03 1.20.1220.12 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III 0.52 41.0 3.60e-01 86.2% 91.1%
7nazA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 41.0 2.96e-01 87.4% 40.0%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3710693 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 53.0 3.65e-01 96.6% 26.3%
3221179 2007.2.3.0 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II 0.55 47.0 3.67e-01 95.4% 76.3%
3997924 109.4.1.301 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Hid1 0.54 47.0 2.87e-01 98.9% 30.4%
3951455 109.4.1.277 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › T7SS_EccA1_N 0.52 41.0 2.90e-01 87.4% 28.4%
3618077 603.1.1.149 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Frag1 0.51 36.0 3.28e-01 74.7% 94.4%
3905342 3579.1.1.1 extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › Oxidored_q3 0.51 35.0 2.82e-01 74.7% 36.5%
D2 high residues 545-702
PDB
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4329001 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.53 39.0 3.11e-01 76.6% 84.5%
D3 medium residues 72-89_196-227_261-317
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2r7rA05 1.10.357.80 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.74 68.0 5.71e-01 100.0% 92.6%
6z74C02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.58 42.0 3.72e-01 76.6% 100.0%
3rc3A01 1.10.1740.140 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.55 32.0 3.29e-01 80.4% 59.2%
2w00A02 3.90.640.50 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › 0.55 24.0 2.87e-01 78.5% 57.5%
2cwlB01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 42.0 3.17e-01 82.2% 82.7%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 40.0 3.65e-01 80.4% 97.4%
2p5kA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 27.0 3.33e-01 79.4% 77.8%
2kr7A02 2.40.10.330 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.53 21.0 2.73e-01 83.2% 61.4%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.52 27.0 3.50e-01 75.7% 93.0%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3397393 603.1.1.101 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_6 0.56 46.0 3.17e-01 89.7% 79.7%
3614219 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.53 43.0 3.01e-01 88.8% 73.2%
4990979 7516.1.1.51 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_21 0.53 47.0 3.31e-01 100.0% 87.8%
4043003 601.7.1.6 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase 0.52 38.0 3.34e-01 78.5% 58.8%
5029865 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.50 43.0 3.94e-01 95.3% 86.8%
D4 medium residues 228-260_318-415_440-452
PDB