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RNA-dependent_RNA_polymerase

Euk-Vir

Beihai_narna-like_virus_4

RNA-dependent_RNA_polymerase__YP_009333266__Beihai_narna-like_virus_4__1922456

Identity

Accession:
YP_009333266 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

73.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D2 medium residues 250-302
PDB
D3 medium residues 365-394_465-520
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.63 44.0 4.71e-01 75.6% 86.3%
6k2eA01 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 40.0 4.47e-01 73.3% 82.4%
2qndA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.63 43.0 4.50e-01 72.1% 95.0%
3pjxA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 54.0 4.31e-01 100.0% 59.7%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 44.0 3.80e-01 74.4% 55.6%
3u1kB04 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.61 43.0 4.57e-01 72.1% 90.3%
1gmuA01 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.61 37.0 4.12e-01 79.1% 77.6%
3oq2A00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 42.0 4.06e-01 73.3% 62.6%
3encA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.61 43.0 4.46e-01 73.3% 93.7%
2jzxA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.61 43.0 4.50e-01 75.6% 93.7%
1s7hA01 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 43.0 4.47e-01 74.4% 81.2%
4mz0B05 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.60 38.0 4.22e-01 70.9% 82.1%
1khmA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.60 42.0 4.23e-01 74.4% 83.1%
4g08A02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.59 42.0 4.57e-01 74.4% 97.1%
2ctlA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.59 42.0 4.07e-01 75.6% 77.3%
1mw7A03 3.30.70.980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain 0.58 41.0 4.34e-01 75.6% 84.0%
1earA02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.58 36.0 3.90e-01 73.3% 76.8%
2dgrA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.58 39.0 4.31e-01 70.9% 98.5%
3wy7D01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 41.0 3.75e-01 80.2% 92.5%
1mg7A01 3.30.70.1000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Switch protein XOL-1, GHMP-like 0.55 48.0 3.83e-01 97.7% 61.1%
5vnxA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 41.0 3.62e-01 83.7% 85.2%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3442371 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.70 49.0 5.02e-01 73.3% 80.0%
5065755 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 47.0 3.92e-01 70.9% 64.0%
4058379 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.68 43.0 4.87e-01 70.9% 84.6%
5035757 1036.1.1.1 a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.67 49.0 4.60e-01 77.9% 67.6%
4163010 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.65 47.0 4.57e-01 75.6% 78.9%
4215184 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.65 42.0 4.62e-01 72.1% 81.4%
4156329 304.11.1.4 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › FAS_AT_central 0.64 45.0 4.69e-01 74.4% 83.7%
5050432 1036.1.1.1 a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.63 47.0 4.39e-01 80.2% 70.0%
5080869 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.63 43.0 4.35e-01 70.9% 91.8%
5000489 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.62 39.0 3.53e-01 72.1% 47.0%
5011347 304.102.1.2 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD 0.62 45.0 3.45e-01 76.7% 77.9%
4070496 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.61 41.0 4.35e-01 75.6% 78.7%
4011868 327.16.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system 0.61 43.0 4.58e-01 74.4% 93.3%
3706688 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.61 41.0 4.59e-01 70.9% 96.9%
5032609 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.61 43.0 4.53e-01 74.4% 97.3%
4493767 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.60 40.0 4.32e-01 75.6% 84.3%
3210821 327.16.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system 0.59 42.0 4.41e-01 74.4% 88.0%
4666425 304.11.1.2 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › SAT 0.59 41.0 4.29e-01 70.9% 86.7%
4357399 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.59 40.0 4.35e-01 79.1% 87.1%
3955181 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.58 43.0 3.23e-01 96.5% 31.6%
4987106 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.58 42.0 4.08e-01 75.6% 68.4%
1487486 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.57 39.0 3.83e-01 72.1% 89.8%
3669942 3016.1.1.1 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.57 40.0 3.84e-01 73.3% 96.0%
5011645 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.57 38.0 4.03e-01 70.9% 78.7%
4172605 3016.1.1.1 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.56 40.0 3.93e-01 75.6% 76.8%
3209439 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.56 48.0 3.34e-01 100.0% 92.5%
5000291 101.1.2.28 alpha arrays › HTH › HTH › winged helix domain › eIF-5_eIF-2B 0.55 39.0 3.89e-01 75.6% 73.3%
4152585 3016.1.1.1 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.55 37.0 3.71e-01 70.9% 95.6%
3652122 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.54 41.0 3.30e-01 82.6% 62.2%
3924844 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.54 39.0 3.47e-01 77.9% 93.8%
4825869 4271.1.1.3 alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.52 38.0 3.14e-01 91.9% 40.2%
D4 medium residues 521-575
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2bbhA01 3.30.460.20 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › CorA soluble domain-like 0.77 48.0 3.40e-01 72.7% 22.5%
2r5rA00 3.10.270.10 Alpha Beta › Roll › Urate Oxidase › Urate Oxidase; 0.76 63.0 4.10e-01 94.5% 48.8%
3c8iA00 2.40.410.10 Mainly Beta › Beta Barrel › putative membrane protein from Corynebacterium diphtheriae fold › putative membrane protein from Corynebacterium diphtheriae superfamily 0.69 43.0 3.33e-01 70.9% 27.6%
3fhwA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 48.0 3.99e-01 74.5% 45.5%
3hvnA02 3.30.1040.20 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.69 50.0 5.07e-01 78.2% 81.1%
3bhcA01 3.30.460.20 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › CorA soluble domain-like 0.68 44.0 3.44e-01 72.7% 30.1%
3j7aV00 2.40.50.1000 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.68 46.0 3.39e-01 76.4% 26.7%
2vg9A00 2.60.120.180 Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain 0.67 47.0 3.09e-01 74.5% 18.4%
6rtqA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.67 50.0 3.79e-01 80.0% 48.1%
3en2A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.67 46.0 3.98e-01 72.7% 46.2%
3obaA01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.66 47.0 3.20e-01 76.4% 73.5%
3ub1A01 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 47.0 3.62e-01 78.2% 39.0%
3wp4A00 2.60.120.180 Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain 0.66 45.0 2.93e-01 74.5% 17.1%
3o2zF00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.65 43.0 3.95e-01 76.4% 50.6%
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.65 43.0 3.48e-01 74.5% 34.9%
1pfoA02 3.30.1040.20 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.65 46.0 4.74e-01 78.2% 81.1%
1olzA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 50.0 2.91e-01 85.5% 42.1%
3ulpD00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.63 45.0 3.68e-01 78.2% 40.7%
5vqjA00 2.60.120.180 Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain 0.62 43.0 2.87e-01 74.5% 18.5%
1vk3A02 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.61 47.0 3.60e-01 85.5% 83.7%
3d4eA02 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.61 39.0 3.54e-01 72.7% 46.2%
4n1vA00 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.61 45.0 3.94e-01 83.6% 52.7%
3t1oA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 43.0 2.97e-01 78.2% 21.4%
3wa5B00 2.60.120.1690 Mainly Beta › Sandwich › Jelly Rolls › 0.61 39.0 3.09e-01 74.5% 29.0%
2w4yA00 2.40.160.220 Mainly Beta › Beta Barrel › Porin › 0.61 47.0 3.67e-01 85.5% 45.9%
4bqqB02 3.90.1750.20 Alpha Beta › Alpha-Beta Complex › Hect, E3 ligase catalytic domain fold › Putative Large Serine Recombinase; Chain B, Domain 2 0.60 42.0 2.91e-01 74.5% 27.9%
4wrnA02 2.60.40.3210 Mainly Beta › Sandwich › Immunoglobulin-like › Zona pellucida, ZP-N domain 0.60 45.0 3.66e-01 81.8% 42.9%
3ddcB00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.60 45.0 3.50e-01 85.5% 40.6%
1pn2B01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.59 41.0 3.00e-01 76.4% 26.4%
3soyA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 41.0 3.17e-01 76.4% 29.6%
2imjD01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.58 44.0 3.28e-01 81.8% 71.8%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.58 42.0 3.11e-01 80.0% 45.5%
2n8xA00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.58 43.0 3.23e-01 87.3% 80.1%
1v1qA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 40.0 3.38e-01 78.2% 41.8%
4q3lB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 44.0 2.81e-01 85.5% 25.4%
6lofA00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.57 39.0 2.92e-01 80.0% 25.3%
3aabB00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 40.0 3.30e-01 80.0% 40.6%
3robA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 40.0 3.12e-01 78.2% 32.8%
2bolA03 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 35.0 3.04e-01 78.2% 38.7%
6yfiB01 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.55 42.0 3.21e-01 83.6% 40.0%
2bjoA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.55 39.0 3.36e-01 78.2% 57.4%
6zj8D01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.54 39.0 3.22e-01 80.0% 41.2%
1p1hB01 3.30.2360.10 Alpha Beta › 2-Layer Sandwich › Glyceraldehyde-3-phosphate dehydrogenase-like fold › Glyceraldehyde-3-phosphate dehydrogenase-like domain 0.54 42.0 3.07e-01 90.9% 27.8%
1l3aA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.54 40.0 2.91e-01 81.8% 28.9%
2liyA00 2.20.25.390 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › Stomagen 0.54 35.0 3.88e-01 70.9% 82.2%
3aonA00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 39.0 2.81e-01 92.7% 22.9%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.54 41.0 2.78e-01 87.3% 32.2%
3hm2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 36.0 2.66e-01 72.7% 24.0%
3ff2A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 37.0 3.02e-01 80.0% 35.9%
5azsA02 2.20.200.10 Mainly Beta › Single Sheet › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.51 38.0 3.42e-01 83.6% 94.0%
4tw1B00 2.70.240.10 Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/porin MspA 0.51 41.0 2.73e-01 98.2% 64.2%
4aghA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.51 38.0 3.31e-01 78.2% 60.0%
1ocsA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.51 37.0 2.84e-01 78.2% 56.8%
7w3rB01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.50 42.0 2.64e-01 94.5% 55.8%
ECOD (83)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3614657 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.84 68.0 3.89e-01 87.3% 10.9%
4947171 2.1.1.4 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17 0.73 50.0 4.05e-01 76.4% 38.1%
3600488 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.72 52.0 3.94e-01 76.4% 68.8%
4133928 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.72 58.0 4.52e-01 89.1% 96.7%
4856335 2.1.1.5 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17,Ribosomal_S17_N 0.72 49.0 3.57e-01 76.4% 26.3%
3474593 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.71 55.0 4.02e-01 87.3% 48.8%
4629438 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.71 53.0 4.25e-01 81.8% 97.3%
4119784 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.71 53.0 4.16e-01 83.6% 88.7%
3405436 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.70 50.0 3.99e-01 80.0% 36.5%
3284948 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 51.0 4.44e-01 78.2% 54.1%
3713176 5.1.4.223 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RIC1_2nd 0.70 57.0 3.46e-01 92.7% 34.7%
4196358 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.70 56.0 4.37e-01 89.1% 95.8%
4014355 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.69 51.0 4.46e-01 80.0% 67.1%
4635289 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 60.0 3.59e-01 100.0% 45.1%
4945010 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.68 58.0 3.57e-01 96.4% 77.3%
4012024 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.68 48.0 3.09e-01 76.4% 15.0%
3782159 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.67 49.0 4.17e-01 80.0% 85.3%
3479176 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.67 45.0 3.97e-01 80.0% 47.5%
3232066 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.67 50.0 3.04e-01 81.8% 62.4%
3498230 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.67 45.0 3.96e-01 80.0% 47.5%
4586646 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.67 51.0 4.05e-01 87.3% 86.4%
4544858 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 56.0 3.35e-01 100.0% 16.2%
4361292 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 56.0 3.36e-01 100.0% 47.4%
4000227 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 49.0 4.10e-01 80.0% 87.4%
1555393 2.1.1.4 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17 0.66 47.0 3.60e-01 78.2% 32.3%
2997715 11.13.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › Leukocidin-like › Leukocidin-like › Leukocidin 0.65 54.0 3.46e-01 94.5% 81.4%
4635290 4967.1.1.25 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.65 55.0 3.31e-01 100.0% 14.4%
4955607 3435.1.1.0 a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC 0.65 49.0 3.37e-01 85.5% 33.5%
4088089 304.48.1.39 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.65 51.0 3.28e-01 90.9% 19.7%
3730893 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.65 47.0 4.03e-01 80.0% 84.2%
3489971 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.65 47.0 3.75e-01 80.0% 43.3%
3924081 2.1.1.6 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB 0.64 45.0 3.47e-01 76.4% 33.6%
4666185 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 53.0 3.22e-01 100.0% 13.7%
4396101 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 53.0 3.21e-01 100.0% 50.5%
5067682 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.64 44.0 3.78e-01 74.5% 44.4%
4856794 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.64 46.0 4.21e-01 81.8% 57.1%
4126255 4967.1.1.25 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.64 52.0 3.44e-01 100.0% 26.5%
3624550 6043.1.1.4 a+b two layers › yfeY-like › yfeY-like › yfeY-like › PHAF1 0.63 46.0 3.44e-01 78.2% 32.0%
4965880 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.63 45.0 2.97e-01 78.2% 16.9%
3591503 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 45.0 3.29e-01 76.4% 48.3%
3919375 77.2.1.1 beta meanders › open-sided beta-meander › Histone H3 K4-specific methyltransferase SET7/9-N › Histone H3 K4-specific methyltransferase SET7/9-N › MORN 0.63 48.0 4.00e-01 83.6% 56.0%
3899290 11.1.1.1054 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF26562 0.63 44.0 3.50e-01 74.5% 35.7%
2388815 5.1.4.292 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, CAF1C_H4-bd, Beta-prop_EIPR1 0.62 42.0 3.73e-01 72.7% 47.0%
4241274 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 50.0 3.09e-01 100.0% 17.2%
4927158 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.62 53.0 3.11e-01 98.2% 71.0%
3707076 511.1.1.0 beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.62 51.0 3.81e-01 100.0% 89.2%
3246209 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.62 46.0 3.32e-01 85.5% 37.8%
3794270 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 46.0 3.99e-01 81.8% 54.1%
4486052 304.48.1.39 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.61 48.0 3.04e-01 94.5% 19.4%
3534592 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.61 43.0 4.40e-01 76.4% 76.4%
3416305 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.61 45.0 2.80e-01 81.8% 23.1%
5054294 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.60 43.0 3.64e-01 78.2% 63.0%
3410286 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.60 42.0 3.63e-01 78.2% 44.2%
3801441 304.112.1.1 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain › ArgoL1 0.60 43.0 3.04e-01 78.2% 23.2%
3913066 223.2.1.36 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_3 0.60 37.0 2.59e-01 78.2% 18.0%
3892768 11.1.1.1054 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF26562 0.60 42.0 3.41e-01 78.2% 36.7%
5056319 177.1.1.0 alpha bundles › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease 0.59 44.0 3.08e-01 76.4% 30.3%
3521712 109.6.1.1 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF 0.59 40.0 2.44e-01 70.9% 18.1%
3249666 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.59 44.0 3.09e-01 85.5% 85.7%
5050618 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 40.0 3.10e-01 78.2% 28.6%
3380753 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.59 43.0 3.71e-01 80.0% 48.9%
3925857 11.1.1.673 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CUT_N 0.59 43.0 3.51e-01 78.2% 41.0%
3716792 511.1.1.0 beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.59 47.0 3.57e-01 94.5% 84.6%
3773735 11.1.1.640 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.58 43.0 3.52e-01 81.8% 45.5%
4640369 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.58 41.0 3.36e-01 80.0% 39.0%
3457651 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.58 39.0 2.50e-01 78.2% 13.3%
3472421 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.58 44.0 3.30e-01 81.8% 73.8%
3654114 2484.1.1.26 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.58 41.0 2.89e-01 80.0% 31.4%
4983910 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.58 41.0 3.23e-01 78.2% 51.5%
4159896 2003.1.1.59 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_5 0.58 45.0 2.76e-01 90.9% 12.3%
3486945 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.57 44.0 3.42e-01 87.3% 70.8%
3627506 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.57 39.0 3.17e-01 80.0% 36.4%
3965061 5084.3.1.1 beta barrels › Outer membrane meander beta-barrels › Autotransporter › Autotransporter › Autotransporter 0.56 45.0 3.02e-01 94.5% 56.9%
3761138 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.55 40.0 3.26e-01 80.0% 61.7%
None 0.55 44.0 3.00e-01 100.0% 58.9%
5040847 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.55 40.0 2.59e-01 81.8% 36.3%
3709357 2003.1.1.59 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_5 0.55 41.0 2.85e-01 87.3% 22.0%
3770608 11.1.1.640 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.54 39.0 3.09e-01 78.2% 35.8%
3249225 223.2.1.6 a+b three layers › Profilin-like › profilin-like › profilin-like › uDENN 0.54 45.0 3.37e-01 100.0% 86.9%
3601335 298.1.1.0 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.53 42.0 3.15e-01 100.0% 82.8%
3899631 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 36.0 2.56e-01 80.0% 52.6%
4956927 239.1.1.0 beta barrels › Ribosomal protein L25-like › Ribosomal protein L25-like › Ribosomal protein L25-like 0.51 43.0 3.19e-01 98.2% 90.3%
3675789 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 37.0 3.47e-01 80.0% 94.3%