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RNA-dependent_RNA_polymerase
Euk-VirBeihai_narna-like_virus_10
RNA-dependent_RNA_polymerase__YP_009333271__Beihai_narna-like_virus_10__1922437
Identity
- Accession:
- YP_009333271 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
77.8
mean pLDDT
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-91
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337311__Changjiang_narna-like_virus_2__1922777__D114-243
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7w5gA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.62 | 55.0 | 3.72e-01 | 100.0% | 41.8% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 38.0 | 3.31e-01 | 73.6% | 80.3% |
| 4bujE03 | 1.10.3380.30 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › | 0.54 | 46.0 | 3.60e-01 | 100.0% | 94.2% |
| 3efoB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.54 | 41.0 | 3.45e-01 | 100.0% | 48.3% |
| 5c50B00 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.54 | 40.0 | 3.24e-01 | 80.2% | 78.9% |
| 4l7nA01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.53 | 45.0 | 3.95e-01 | 95.6% | 62.2% |
| 2k36A00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.53 | 38.0 | 3.34e-01 | 78.0% | 51.7% |
| 3c4rA00 | 1.10.3600.10 | Mainly Alpha › Orthogonal Bundle › uncharacterized protein encoded by cryptic prophage fold › Putative bacterial toxin ydaT | 0.52 | 33.0 | 3.03e-01 | 100.0% | 47.6% |
| 4cclA02 | 3.40.366.30 | Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › 50S ribosomal protein L16 arginine hydroxylase; Chain A, Domain 2 | 0.51 | 42.0 | 3.52e-01 | 92.3% | 63.1% |
| 2jokA01 | 1.10.4120.10 | Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain | 0.51 | 44.0 | 3.66e-01 | 100.0% | 76.6% |
| 1egdA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 37.0 | 3.27e-01 | 80.2% | 87.2% |
| 1vnsA01 | 1.20.144.10 | Mainly Alpha › Up-down Bundle › Vanadium-containing Chloroperoxidase; domain 1 › Phosphatidic acid phosphatase type 2/haloperoxidase | 0.50 | 43.0 | 3.59e-01 | 100.0% | 89.1% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3477262 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.62 | 48.0 | 3.91e-01 | 83.5% | 89.7% |
| 3973899 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.62 | 47.0 | 4.06e-01 | 81.3% | 87.6% |
| 2886244 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.60 | 47.0 | 3.45e-01 | 83.5% | 85.6% |
| 4944950 | 1075.4.1.30 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran | 0.58 | 40.0 | 2.83e-01 | 72.5% | 52.4% |
| 3937183 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 42.0 | 3.69e-01 | 80.2% | 96.6% |
| 4973230 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.56 | 47.0 | 3.66e-01 | 95.6% | 76.8% |
| 4083451 | 192.2.1.20 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ASNSD1-SEP | 0.55 | 38.0 | 4.08e-01 | 80.2% | 82.5% |
| 3396357 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.55 | 45.0 | 4.55e-01 | 100.0% | 93.3% |
| 3203655 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.54 | 39.0 | 3.43e-01 | 90.1% | 49.3% |
| 3250971 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.54 | 47.0 | 4.62e-01 | 100.0% | 98.0% |
| 4683333 | 138.1.1.5 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA_pol3_gamma3 | 0.54 | 45.0 | 4.15e-01 | 98.9% | 70.8% |
| 3212929 | 3525.1.1.1 ↗ | alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › BET | 0.54 | 29.0 | 3.27e-01 | 97.8% | 67.1% |
| 2984191 | 3524.1.1.0 ↗ | alpha arrays › Uncharacterized protein encoded by cryptic prophage › Uncharacterized protein encoded by cryptic prophage › Uncharacterized protein encoded by cryptic prophage | 0.51 | 33.0 | 2.97e-01 | 98.9% | 45.7% |
| 4031800 | 102.1.3.13 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain › YpoC | 0.51 | 35.0 | 3.37e-01 | 70.3% | 90.7% |
| 3742209 | 6140.1.1.0 ↗ | alpha superhelices › Cdc45-Binding Domain in Sld3/Treslin › Cdc45-Binding Domain in Sld3/Treslin › Cdc45-Binding Domain in Sld3/Treslin | 0.51 | 41.0 | 3.18e-01 | 91.2% | 68.1% |
| 3502310 | 109.4.1.370 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Symplekin_C | 0.51 | 45.0 | 2.75e-01 | 97.8% | 19.8% |
| 5056212 | 1079.1.1.8 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE | 0.51 | 42.0 | 3.41e-01 | 95.6% | 72.7% |
| 4144542 | 132.1.1.1 ↗ | alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding | 0.51 | 45.0 | 4.35e-01 | 98.9% | 96.2% |
D2
medium
residues 92-114_138-228_327-351
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009336851__Hubei_narna-like_virus_11__1922941__D249-287_609-635_740-780
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2l66A00 | 2.10.260.10 | Mainly Beta › Ribbon › Pemi-like Protein 1; Chain: D › | 0.50 | 17.0 | 2.62e-01 | 79.1% | 73.6% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3792091 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.51 | 40.0 | 2.99e-01 | 83.5% | 49.3% |
| 3598902 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.50 | 40.0 | 2.87e-01 | 83.5% | 50.8% |
D3
medium
residues 115-137_229-326_352-391
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009333146__Beihai_narna-like_virus_26__1922454__D105-147_243-381
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8e83B01 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.57 | 42.0 | 3.10e-01 | 76.4% | 79.0% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.52 | 25.0 | 3.34e-01 | 72.0% | 83.1% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4932719 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.56 | 44.0 | 3.34e-01 | 83.9% | 93.5% |
| 4028961 | 604.32.1.0 ↗ | alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY | 0.55 | 30.0 | 2.86e-01 | 95.7% | 41.6% |
| 3402544 | 137.1.1.12 ↗ | alpha bundles › A DNA-binding domain in eukaryotic transcription factors › A DNA-binding domain in eukaryotic transcription factors › A DNA-binding domain in eukaryotic transcription factors › SCHIP-1_C | 0.54 | 24.0 | 3.04e-01 | 87.6% | 67.4% |
| 3816080 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 29.0 | 3.04e-01 | 91.9% | 56.6% |
| 3609510 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.52 | 21.0 | 2.02e-01 | 88.8% | 28.6% |
D4
medium
residues 536-669
D5
medium
residues 672-724