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RNA-dependent_RNA_polymerase

Euk-Vir

Beihai_narna-like_virus_11

RNA-dependent_RNA_polymerase__YP_009333278__Beihai_narna-like_virus_11__1922438

Identity

Accession:: YP_009333278 ↗
Protein ID:: RNA-dependent_RNA_polymerase
Kingdom:: euk

Quality

76.8 mean pLDDT

Cluster

View cluster (39 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 15-198

PDB

Domain cluster: representative

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3vwbA00	1.10.10.2830	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.56	34.0	4.12e-01	87.0%	94.0%
5mmjh01	3.30.1370.30	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 ›	0.52	22.0	3.26e-01	77.2%	93.3%
4zvaA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.51	29.0	3.15e-01	86.4%	65.1%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4528027	242.4.1.2 ↗	a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain › PolC_DP2_central	0.62	36.0	4.33e-01	83.2%	85.8%
4991837	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.56	30.0	4.07e-01	81.5%	100.0%
3710041	3615.1.1.0 ↗	alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain	0.54	40.0	3.71e-01	100.0%	60.0%
5035107	3922.1.1.358 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF26119	0.52	22.0	2.72e-01	91.8%	60.5%

D2 medium residues 199-275_294-383_397-460

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009333261__Beihai_narna-like_virus_23__1922451__D199-311_371-432

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4xaxB02	1.20.58.1290	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain	0.50	20.0	2.92e-01	87.0%	78.8%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1695458	304.48.1.7 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1	0.81	76.0	5.93e-01	100.0%	79.1%
1699894	304.48.2.2 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › 'palm' domain in birnaviruse RNA-dependent RNA polymerase › Permu_RdRp_palm	0.77	73.0	5.47e-01	100.0%	71.9%
3615272	304.48.1.25 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4	0.67	56.0	4.68e-01	87.9%	59.5%
3598902	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.66	55.0	4.65e-01	87.4%	59.7%
4516798	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.64	51.0	4.09e-01	83.5%	43.7%
3960648	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.62	50.0	4.55e-01	82.7%	65.2%
3792091	304.48.1.25 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4	0.61	51.0	4.45e-01	87.4%	59.1%
3737536	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.55	43.0	3.97e-01	93.1%	63.4%
4296494	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.54	42.0	3.82e-01	93.1%	61.0%

D3 medium residues 384-396_461-538

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009342440__Wuhan_insect_virus_18__1923722__D388-416_481-565_595-607

D4 medium residues 575-645

PDB

Domain cluster: representative

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
8e9gE01	1.10.10.1590	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E	0.60	41.0	4.27e-01	83.1%	79.4%
4wvaB00	1.50.10.10	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase ›	0.58	51.0	3.15e-01	100.0%	56.3%
3ii9B01	1.10.540.10	Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain	0.56	43.0	3.61e-01	85.9%	56.9%
3pasA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.53	37.0	2.79e-01	74.6%	45.8%
1udyA01	1.10.540.10	Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain	0.52	40.0	3.51e-01	90.1%	70.8%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3577241	5054.1.1.2 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans	0.67	41.0	3.41e-01	97.2%	35.8%
3611423	3444.1.1.0 ↗	alpha arrays › DP domain › DP domain › DP domain	0.65	40.0	4.09e-01	93.0%	62.9%
3871192	223.2.1.25 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Avl9	0.51	37.0	2.57e-01	78.9%	26.7%

D5 medium residues 646-665_678-726

PDB