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RNA-dependent_RNA_polymerase
Euk-VirHubei_narna-like_virus_11
RNA-dependent_RNA_polymerase__YP_009336851__Hubei_narna-like_virus_11__1922941
Identity
- Accession:
- YP_009336851 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
51.6
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 119-248
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337311__Changjiang_narna-like_virus_2__1922777__D114-243
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 40.0 | 3.95e-01 | 79.2% | 76.7% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 38.0 | 3.58e-01 | 71.5% | 87.3% |
| 1u61A00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.53 | 36.0 | 3.67e-01 | 95.4% | 69.3% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 46.0 | 3.79e-01 | 100.0% | 81.9% |
| 1vnsA01 | 1.20.144.10 | Mainly Alpha › Up-down Bundle › Vanadium-containing Chloroperoxidase; domain 1 › Phosphatidic acid phosphatase type 2/haloperoxidase | 0.52 | 46.0 | 4.15e-01 | 96.9% | 75.4% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 34.0 | 3.77e-01 | 76.2% | 87.9% |
| 2jokA01 | 1.10.4120.10 | Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain | 0.51 | 39.0 | 3.57e-01 | 80.8% | 81.7% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 31.0 | 3.51e-01 | 100.0% | 82.4% |
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.50 | 39.0 | 3.80e-01 | 99.2% | 73.8% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3451722 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.56 | 49.0 | 4.98e-01 | 100.0% | 97.6% |
| 4522486 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 46.0 | 3.64e-01 | 100.0% | 78.6% |
| 3616363 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.51 | 33.0 | 2.71e-01 | 93.1% | 35.3% |
| 3368978 | 5051.1.1.6 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans | 0.50 | 38.0 | 2.76e-01 | 82.3% | 59.5% |
D2
medium
residues 249-287_609-635_740-780
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cqgA02 | 3.10.10.20 | Alpha Beta › Roll › HIV Type 1 Reverse Transcriptase; Chain A, domain 1 › | 0.65 | 39.0 | 4.62e-01 | 100.0% | 90.3% |
| 3jcmH04 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.53 | 26.0 | 3.06e-01 | 83.2% | 64.9% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4638770 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.60 | 29.0 | 3.21e-01 | 87.9% | 55.6% |
| 4183868 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.59 | 32.0 | 3.69e-01 | 100.0% | 72.2% |
| 5015326 | 328.5.1.0 ↗ | a+b two layers › IF3-like › SirA-like › SirA-like | 0.58 | 32.0 | 3.90e-01 | 97.2% | 87.7% |
| 4882475 | 210.1.1.0 ↗ | a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits | 0.55 | 25.0 | 2.84e-01 | 97.2% | 53.5% |
D3
medium
residues 781-840
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fryA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.72 | 50.0 | 4.94e-01 | 96.7% | 68.8% |
| 2ckwA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.72 | 63.0 | 5.12e-01 | 100.0% | 62.9% |
| 5tuuA00 | 1.20.140.80 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Transcription factor DP | 0.71 | 49.0 | 3.64e-01 | 71.7% | 61.8% |
| 2wtvA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.64 | 43.0 | 3.08e-01 | 70.0% | 25.9% |
| 1kkhA01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.62 | 47.0 | 3.44e-01 | 86.7% | 50.3% |
| 1ztdA00 | 1.10.1520.20 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III | 0.57 | 49.0 | 3.88e-01 | 96.7% | 88.8% |
| 4i8oA04 | 6.10.250.2650 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 45.0 | 3.84e-01 | 86.7% | 99.0% |
| 3cmnA01 | 1.20.150.30 | Mainly Alpha › Up-down Bundle › Lysin › Zincin-like metallopeptidase, N-terminal domain | 0.52 | 37.0 | 3.06e-01 | 76.7% | 42.7% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3306901 | 304.48.1.43 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mitovir_RNA_pol | 0.85 | 71.0 | 5.09e-01 | 100.0% | 33.3% |
| 3963044 | 101.1.11.116 ↗ | alpha arrays › HTH › HTH › Ribbon-helix-helix › Transposase_mut | 0.65 | 55.0 | 4.99e-01 | 91.7% | 87.5% |
| 3214818 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.65 | 57.0 | 3.52e-01 | 100.0% | 20.5% |
| 3477357 | 2498.1.1.9 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 | 0.62 | 49.0 | 3.63e-01 | 91.7% | 64.6% |
| 4997766 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.58 | 47.0 | 3.99e-01 | 96.7% | 53.3% |
D4
medium
residues 887-974