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RNA-dependent_RNA_polymerase
Euk-VirBeihai_weivirus-like_virus_17
RNA-dependent_RNA_polymerase__YP_009336943__Beihai_weivirus-like_virus_17__1922745
Identity
- Accession:
- YP_009336943 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
63.0
mean pLDDT
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 20-157
D2
high
residues 697-833
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1e5rB02 | 1.10.1720.10 | Mainly Alpha › Orthogonal Bundle › Proline Oxidase; Chain: A, Domain 2 › L-proline 3-hydroxylase, C-terminal domain | 0.58 | 29.0 | 3.54e-01 | 97.1% | 75.0% |
| 6h5hA00 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.55 | 25.0 | 3.48e-01 | 81.0% | 85.9% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3663066 | 611.3.1.1 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 | 0.63 | 32.0 | 3.69e-01 | 75.9% | 66.0% |
| 4973692 | 182.1.3.0 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX | 0.55 | 26.0 | 2.96e-01 | 92.0% | 58.0% |
| 3627573 | 192.17.1.10 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › eIF-3c_N | 0.51 | 35.0 | 3.85e-01 | 78.1% | 84.3% |
D3
medium
residues 304-386_420-451_487-549
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.64 | 57.0 | 4.06e-01 | 96.1% | 58.8% |
| 1y96A00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.55 | 17.0 | 2.45e-01 | 98.3% | 57.0% |
| 1fm2B03 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.53 | 17.0 | 2.78e-01 | 89.3% | 75.8% |
| 4wksC02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.53 | 18.0 | 2.71e-01 | 89.3% | 69.3% |
| 6nvxB02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.52 | 18.0 | 2.68e-01 | 89.3% | 68.8% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3667875 | 67.1.1.0 ↗ | beta sandwiches › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain | 0.59 | 14.0 | 2.57e-01 | 96.1% | 61.8% |
| 3236920 | 106.1.1.8 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › HisK-N-like | 0.53 | 38.0 | 4.07e-01 | 73.0% | 98.0% |
D4
medium
residues 452-486_550-696
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cqgA04 | 3.30.70.2630 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.70 | 40.0 | 5.09e-01 | 97.8% | 96.2% |
| 1lfwA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 37.0 | 4.66e-01 | 82.4% | 100.0% |
| 2f5gA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.61 | 35.0 | 4.10e-01 | 84.1% | 78.5% |
| 2rilA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 33.0 | 4.33e-01 | 84.1% | 97.9% |
| 7e6gA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.61 | 43.0 | 4.69e-01 | 89.0% | 87.9% |
| 4zmuA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.60 | 43.0 | 4.65e-01 | 85.2% | 86.5% |
| 2r0cA02 | 3.30.9.10 | Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 › D-Amino Acid Oxidase, subunit A, domain 2 | 0.59 | 31.0 | 3.50e-01 | 85.2% | 64.5% |
| 5k8mA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 40.0 | 4.68e-01 | 82.4% | 99.2% |
| 2a6mA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.55 | 35.0 | 4.13e-01 | 84.6% | 90.0% |
| 1tr0A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 32.0 | 4.04e-01 | 83.5% | 97.2% |
| 3io1A02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 35.0 | 4.26e-01 | 82.4% | 99.1% |
| 3gqcC01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.54 | 37.0 | 4.26e-01 | 83.5% | 93.4% |
| 3mtkA00 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.54 | 44.0 | 4.61e-01 | 91.2% | 95.1% |
| 2ldkA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.53 | 37.0 | 3.84e-01 | 70.3% | 89.0% |
| 1qduB00 | 3.30.70.1470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Caspase-like | 0.53 | 24.0 | 3.29e-01 | 72.5% | 85.2% |
| 4uw2B03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.52 | 33.0 | 3.74e-01 | 85.7% | 81.4% |
| 4jhyA00 | 3.30.530.80 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › | 0.50 | 35.0 | 3.75e-01 | 70.3% | 95.5% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3701279 | 304.107.1.10 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › BBS7_pf | 0.67 | 36.0 | 4.86e-01 | 73.6% | 100.0% |
| 3579823 | 331.18.1.5 ↗ | a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › PTHB1_pf | 0.66 | 35.0 | 4.62e-01 | 83.5% | 93.0% |
| 4309142 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.65 | 38.0 | 4.91e-01 | 87.4% | 100.0% |
| 3926438 | 304.48.1.37 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_2 | 0.65 | 57.0 | 5.13e-01 | 97.8% | 68.8% |
| 3227424 | 331.18.1.8 ↗ | a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › BBS7_pf | 0.65 | 37.0 | 4.71e-01 | 76.4% | 96.2% |
| 3704170 | 331.2.1.10 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PTHB1_pf | 0.63 | 34.0 | 4.54e-01 | 74.7% | 98.9% |
| 4297402 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.62 | 54.0 | 4.44e-01 | 92.3% | 69.2% |
| 3389107 | 304.9.1.95 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › DUF4780 | 0.62 | 34.0 | 4.39e-01 | 92.3% | 92.4% |
| 4928686 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.62 | 32.0 | 4.40e-01 | 77.5% | 98.9% |
| 3945039 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.61 | 56.0 | 4.55e-01 | 97.8% | 60.0% |
| 4062713 | 304.48.1.92 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › PF30234 | 0.59 | 40.0 | 4.68e-01 | 96.2% | 99.2% |
| 3484746 | 304.107.1.10 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › BBS7_pf | 0.58 | 36.0 | 4.47e-01 | 72.5% | 100.0% |
| 3291108 | 304.154.1.1 ↗ | a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain › GGDEF_2 | 0.56 | 38.0 | 4.18e-01 | 85.7% | 82.7% |
| 3389647 | 331.18.1.5 ↗ | a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › PTHB1_pf | 0.54 | 35.0 | 4.20e-01 | 75.3% | 96.0% |
| None | — | 0.52 | 44.0 | 2.80e-01 | 91.2% | 67.4% | |
| 3887495 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.52 | 33.0 | 4.04e-01 | 72.5% | 100.0% |
| 3683716 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.52 | 34.0 | 3.08e-01 | 87.4% | 46.8% |
| 3415300 | 304.28.1.5 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › NPC1_MLD | 0.52 | 44.0 | 3.00e-01 | 92.3% | 64.6% |
| 4929832 | 304.5.1.0 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like | 0.52 | 30.0 | 3.80e-01 | 84.1% | 98.1% |
| 3490645 | 304.47.1.0 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain | 0.51 | 35.0 | 3.98e-01 | 70.3% | 100.0% |
| 3475750 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.50 | 43.0 | 2.72e-01 | 91.8% | 69.2% |