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RNA-dependent_RNA_polymerase
Euk-VirBeihai_weivirus-like_virus_2
RNA-dependent_RNA_polymerase__YP_009336960__Beihai_weivirus-like_virus_2__1922748
Identity
- Accession:
- YP_009336960 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
75.1
mean pLDDT
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 11-127
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337047__Beihai_weivirus-like_virus_7__1922754__D6-140
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fcyA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.72 | 35.0 | 4.24e-01 | 86.3% | 69.2% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 44.0 | 4.71e-01 | 89.7% | 73.5% |
| 3tl4X02 | 1.10.10.2420 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.68 | 38.0 | 4.65e-01 | 88.0% | 88.9% |
| 2c42A03 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.64 | 40.0 | 3.31e-01 | 84.6% | 34.0% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.61 | 41.0 | 4.17e-01 | 88.0% | 69.6% |
| 2b9sA02 | 1.10.10.41 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 | 0.61 | 39.0 | 4.39e-01 | 84.6% | 86.2% |
| 3toyA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.61 | 37.0 | 3.64e-01 | 99.1% | 55.1% |
| 2x3mA00 | 1.25.40.670 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 38.0 | 3.38e-01 | 82.9% | 44.0% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 42.0 | 4.46e-01 | 81.2% | 84.8% |
| 1gpjA01 | 3.30.460.30 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain | 0.59 | 34.0 | 3.19e-01 | 86.3% | 45.5% |
| 5by7A02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.57 | 38.0 | 3.53e-01 | 91.5% | 54.1% |
| 3bjdA01 | 1.10.1240.20 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain | 0.56 | 32.0 | 3.57e-01 | 85.5% | 72.7% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.56 | 27.0 | 3.16e-01 | 70.9% | 62.2% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.55 | 42.0 | 3.08e-01 | 80.3% | 76.7% |
| 3b0xA01 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.55 | 32.0 | 3.55e-01 | 98.3% | 74.7% |
| 1e6bA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 30.0 | 3.07e-01 | 84.6% | 55.0% |
| 3m9vA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 34.0 | 3.38e-01 | 87.2% | 60.6% |
| 5gj7A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.52 | 34.0 | 3.37e-01 | 82.9% | 61.6% |
| 4mdvB03 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.51 | 27.0 | 2.97e-01 | 94.9% | 62.6% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3274434 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.68 | 40.0 | 4.64e-01 | 88.0% | 81.2% |
| 3257722 | 198.1.1.3 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_1 | 0.68 | 42.0 | 4.91e-01 | 86.3% | 87.1% |
| 3277060 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.64 | 37.0 | 4.50e-01 | 86.3% | 88.0% |
| 3248091 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.64 | 40.0 | 4.60e-01 | 88.0% | 85.9% |
| 3269592 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.64 | 42.0 | 4.77e-01 | 88.9% | 90.6% |
| 3273958 | 198.1.1.10 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2, SapB_1, Saposin | 0.64 | 39.0 | 4.46e-01 | 88.9% | 83.5% |
| 3244588 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.63 | 40.0 | 4.51e-01 | 80.3% | 83.3% |
| 3936293 | 198.1.1.3 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_1 | 0.62 | 37.0 | 4.04e-01 | 86.3% | 71.6% |
| 4090711 | 5067.1.1.8 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › HPP | 0.60 | 45.0 | 4.05e-01 | 100.0% | 57.5% |
| 3925909 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.59 | 45.0 | 4.87e-01 | 83.8% | 93.0% |
| 3280911 | 5069.1.3.58 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DoxX | 0.57 | 28.0 | 3.19e-01 | 70.1% | 60.0% |
| 3740779 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.56 | 30.0 | 3.59e-01 | 80.3% | 78.7% |
| 3165005 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.56 | 34.0 | 3.81e-01 | 82.1% | 77.8% |
| 4275352 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.56 | 28.0 | 3.16e-01 | 97.4% | 60.0% |
| 3782122 | 3771.1.1.1 ↗ | a+b two layers › Central kinetochore subunit CHL4 C-terminal domain › Central kinetochore subunit CHL4 C-terminal domain › Central kinetochore subunit CHL4 C-terminal domain › CENP-N | 0.56 | 33.0 | 3.45e-01 | 85.5% | 62.5% |
| 5076107 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.55 | 31.0 | 3.57e-01 | 91.5% | 78.8% |
| 3743708 | 101.21.1.1 ↗ | alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit › TP6A_N | 0.54 | 41.0 | 4.11e-01 | 84.6% | 76.8% |
| 5001603 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.54 | 39.0 | 4.35e-01 | 84.6% | 97.8% |
| 5062669 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.54 | 27.0 | 3.23e-01 | 74.4% | 71.2% |
| 4352659 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.54 | 42.0 | 3.65e-01 | 82.9% | 54.9% |
| 5066592 | 1030.1.1.0 ↗ | alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 | 0.53 | 39.0 | 4.25e-01 | 81.2% | 91.0% |
| 3963026 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.51 | 41.0 | 3.22e-01 | 87.2% | 63.5% |
| 3222274 | 198.1.1.3 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_1 | 0.51 | 37.0 | 3.98e-01 | 86.3% | 87.0% |
| 3318685 | 284.1.3.2 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › OSR1_C | 0.51 | 34.0 | 3.59e-01 | 92.3% | 75.2% |
| 3957182 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.51 | 44.0 | 3.68e-01 | 94.0% | 66.5% |
| 4990171 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.50 | 44.0 | 3.32e-01 | 96.6% | 94.2% |
| 4115604 | 2003.1.5.82 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 | 0.50 | 44.0 | 3.30e-01 | 99.1% | 69.7% |
D2
high
residues 388-419_808-956
D3
medium
residues 420-474
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6u0m401 | 3.30.1640.10 | Alpha Beta › 2-Layer Sandwich › mini-chromosome maintenance (MCM) complex, chain A, domain 1 › mini-chromosome maintenance (MCM) complex, chain A, domain 1 | 0.51 | 35.0 | 2.85e-01 | 72.7% | 68.8% |
D4
medium
residues 475-555_600-667
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337141__Beihai_weivirus-like_virus_15__1922743__D392-442_461-485_531-592
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.64 | 56.0 | 5.34e-01 | 100.0% | 80.7% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.57 | 29.0 | 4.03e-01 | 94.0% | 96.2% |
| 2wiyA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.53 | 38.0 | 2.85e-01 | 74.5% | 76.6% |
D5
medium
residues 556-599_668-805