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RNA-dependent_RNA_polymerase

Euk-Vir

Beihai_weivirus-like_virus_3

RNA-dependent_RNA_polymerase__YP_009336973__Beihai_weivirus-like_virus_3__1922751

Identity

Accession:
YP_009336973 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

81.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 7-121_178-192
PDB
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.66 39.0 3.34e-01 71.5% 35.4%
4fcyA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.65 33.0 4.18e-01 83.8% 82.1%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.59 28.0 3.21e-01 84.6% 59.6%
3s63A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.58 38.0 4.45e-01 85.4% 96.6%
2nq2A00 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.52 46.0 3.52e-01 98.5% 82.1%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 38.0 3.77e-01 78.5% 100.0%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3927392 198.1.1.1 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 0.67 41.0 5.08e-01 83.8% 98.8%
4528425 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.67 47.0 5.27e-01 83.8% 93.0%
4401833 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.66 45.0 5.01e-01 83.8% 90.0%
4592728 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.63 43.0 5.01e-01 79.2% 98.9%
3244588 371.1.1.0 few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 0.62 37.0 4.33e-01 73.8% 85.6%
5001603 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.59 40.0 4.67e-01 80.8% 100.0%
3605793 604.9.1.0 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 0.58 32.0 4.03e-01 76.9% 90.7%
3806415 4133.1.1.2 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Tic110 0.57 42.0 4.42e-01 80.0% 85.2%
4090711 5067.1.1.8 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › HPP 0.55 42.0 3.99e-01 97.7% 65.6%
4982987 3352.1.1.1 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3 0.53 38.0 2.74e-01 74.6% 59.2%
5066592 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.52 38.0 4.31e-01 96.9% 99.0%
4990171 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.52 40.0 3.11e-01 81.5% 94.6%
5052842 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.51 39.0 3.45e-01 80.0% 80.0%
4271175 101.1.2.498 alpha arrays › HTH › HTH › winged helix domain › PF25870 0.51 37.0 3.66e-01 80.0% 71.1%
D2 medium residues 242-336_402-431_536-557
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mlqH00 2.40.10.170 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.51 16.0 2.89e-01 73.5% 95.2%
D3 medium residues 337-350_558-601
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4h8aB01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.61 42.0 4.20e-01 72.4% 83.3%
3ihvA01 1.25.40.890 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 39.0 2.80e-01 75.9% 23.8%
1yvwA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.56 40.0 3.42e-01 74.1% 84.8%
3c7jA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 36.0 3.13e-01 87.9% 41.8%
1xrhD01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.54 43.0 3.60e-01 87.9% 68.9%
1rw9A01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.52 37.0 2.23e-01 74.1% 24.9%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4062015 304.8.1.53 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › GlnD_5th 0.57 49.0 3.67e-01 100.0% 74.2%
3229247 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.56 47.0 3.19e-01 100.0% 83.8%
3971074 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.52 35.0 2.37e-01 70.7% 78.3%
D4 medium residues 351-401_517-535
PDB
Domain cluster: representative
D5 medium residues 609-705
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xg9A02 3.10.25.20 Alpha Beta › Roll › Methionyl-tRNA Fmet Formyltransferase; Chain A, domain 2 › 0.54 24.0 2.93e-01 72.2% 61.3%
1vqwA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 40.0 2.81e-01 87.6% 91.7%
3r2uB01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.50 39.0 2.94e-01 100.0% 32.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3417047 1.1.8.0 beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain 0.54 28.0 3.30e-01 95.9% 72.3%
4464657 274.1.1.0 a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.54 30.0 3.27e-01 97.9% 63.7%
4991631 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.52 45.0 3.43e-01 96.9% 59.6%
5045231 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.50 38.0 3.11e-01 100.0% 41.8%
4938531 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.50 44.0 3.81e-01 100.0% 76.7%