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RNA-dependent_RNA_polymerase
Euk-VirBeihai_weivirus-like_virus_3
RNA-dependent_RNA_polymerase__YP_009336973__Beihai_weivirus-like_virus_3__1922751
Identity
- Accession:
- YP_009336973 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
81.5
mean pLDDT
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 7-121_178-192
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337047__Beihai_weivirus-like_virus_7__1922754__D6-140
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2c42A03 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.66 | 39.0 | 3.34e-01 | 71.5% | 35.4% |
| 4fcyA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.65 | 33.0 | 4.18e-01 | 83.8% | 82.1% |
| 2jvfA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.59 | 28.0 | 3.21e-01 | 84.6% | 59.6% |
| 3s63A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.58 | 38.0 | 4.45e-01 | 85.4% | 96.6% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 46.0 | 3.52e-01 | 98.5% | 82.1% |
| 2wy4A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 38.0 | 3.77e-01 | 78.5% | 100.0% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3927392 | 198.1.1.1 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 | 0.67 | 41.0 | 5.08e-01 | 83.8% | 98.8% |
| 4528425 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.67 | 47.0 | 5.27e-01 | 83.8% | 93.0% |
| 4401833 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.66 | 45.0 | 5.01e-01 | 83.8% | 90.0% |
| 4592728 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.63 | 43.0 | 5.01e-01 | 79.2% | 98.9% |
| 3244588 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.62 | 37.0 | 4.33e-01 | 73.8% | 85.6% |
| 5001603 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.59 | 40.0 | 4.67e-01 | 80.8% | 100.0% |
| 3605793 | 604.9.1.0 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 | 0.58 | 32.0 | 4.03e-01 | 76.9% | 90.7% |
| 3806415 | 4133.1.1.2 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Tic110 | 0.57 | 42.0 | 4.42e-01 | 80.0% | 85.2% |
| 4090711 | 5067.1.1.8 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › HPP | 0.55 | 42.0 | 3.99e-01 | 97.7% | 65.6% |
| 4982987 | 3352.1.1.1 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3 | 0.53 | 38.0 | 2.74e-01 | 74.6% | 59.2% |
| 5066592 | 1030.1.1.0 ↗ | alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 | 0.52 | 38.0 | 4.31e-01 | 96.9% | 99.0% |
| 4990171 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.52 | 40.0 | 3.11e-01 | 81.5% | 94.6% |
| 5052842 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.51 | 39.0 | 3.45e-01 | 80.0% | 80.0% |
| 4271175 | 101.1.2.498 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF25870 | 0.51 | 37.0 | 3.66e-01 | 80.0% | 71.1% |
D2
medium
residues 242-336_402-431_536-557
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3mlqH00 | 2.40.10.170 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.51 | 16.0 | 2.89e-01 | 73.5% | 95.2% |
D3
medium
residues 337-350_558-601
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4h8aB01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.61 | 42.0 | 4.20e-01 | 72.4% | 83.3% |
| 3ihvA01 | 1.25.40.890 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 39.0 | 2.80e-01 | 75.9% | 23.8% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.56 | 40.0 | 3.42e-01 | 74.1% | 84.8% |
| 3c7jA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 36.0 | 3.13e-01 | 87.9% | 41.8% |
| 1xrhD01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.54 | 43.0 | 3.60e-01 | 87.9% | 68.9% |
| 1rw9A01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.52 | 37.0 | 2.23e-01 | 74.1% | 24.9% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4062015 | 304.8.1.53 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › GlnD_5th | 0.57 | 49.0 | 3.67e-01 | 100.0% | 74.2% |
| 3229247 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.56 | 47.0 | 3.19e-01 | 100.0% | 83.8% |
| 3971074 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.52 | 35.0 | 2.37e-01 | 70.7% | 78.3% |
D4
medium
residues 351-401_517-535
Domain cluster:
representative
D5
medium
residues 609-705
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xg9A02 | 3.10.25.20 | Alpha Beta › Roll › Methionyl-tRNA Fmet Formyltransferase; Chain A, domain 2 › | 0.54 | 24.0 | 2.93e-01 | 72.2% | 61.3% |
| 1vqwA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.50 | 40.0 | 2.81e-01 | 87.6% | 91.7% |
| 3r2uB01 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.50 | 39.0 | 2.94e-01 | 100.0% | 32.9% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3417047 | 1.1.8.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain | 0.54 | 28.0 | 3.30e-01 | 95.9% | 72.3% |
| 4464657 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.54 | 30.0 | 3.27e-01 | 97.9% | 63.7% |
| 4991631 | 247.1.1.11 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 | 0.52 | 45.0 | 3.43e-01 | 96.9% | 59.6% |
| 5045231 | 247.1.1.11 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 | 0.50 | 38.0 | 3.11e-01 | 100.0% | 41.8% |
| 4938531 | 247.1.1.30 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 | 0.50 | 44.0 | 3.81e-01 | 100.0% | 76.7% |