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RNA-dependent_RNA_polymerase

Euk-Vir

Wenling_narna-like_virus_4

RNA-dependent_RNA_polymerase__YP_009337133__Wenling_narna-like_virus_4__1923504

Identity

Accession:
YP_009337133 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

73.8 mean pLDDT

Cluster

View cluster (32 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 17-120
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ckwA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.69 41.0 3.99e-01 100.0% 53.4%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.68 32.0 4.34e-01 99.0% 84.5%
4a64C03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.64 31.0 3.20e-01 99.0% 48.0%
4dhiB02 1.20.1300.20 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 0.63 37.0 3.37e-01 77.9% 41.4%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.62 45.0 4.46e-01 100.0% 70.8%
2a19A02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.62 45.0 4.91e-01 100.0% 94.1%
1yz6A02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.61 45.0 4.85e-01 99.0% 94.3%
2dgzA01 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.60 43.0 4.61e-01 100.0% 87.6%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.60 45.0 3.74e-01 79.8% 66.1%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 41.0 3.87e-01 100.0% 63.4%
1wxpA01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.56 32.0 3.51e-01 93.3% 66.7%
3fyaB00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 37.0 4.18e-01 95.2% 89.6%
4hjzA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.54 39.0 3.29e-01 75.0% 53.0%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 35.0 3.47e-01 89.4% 61.8%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 38.0 3.54e-01 100.0% 58.5%
1eq1A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.53 47.0 4.05e-01 100.0% 72.3%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.52 47.0 4.13e-01 100.0% 68.6%
1nxuA01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.52 37.0 4.13e-01 97.1% 98.7%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 33.0 3.27e-01 100.0% 60.0%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.51 37.0 3.76e-01 100.0% 75.7%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.51 40.0 3.68e-01 87.5% 100.0%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3394199 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.66 40.0 3.64e-01 98.1% 45.0%
4029006 3291.1.1.20 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › RIFIN 0.66 51.0 4.23e-01 100.0% 47.2%
3395749 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.65 38.0 3.51e-01 99.0% 43.7%
3408207 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.64 38.0 3.45e-01 99.0% 43.6%
4789617 5054.1.1.8 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.62 41.0 4.27e-01 99.0% 73.4%
4028744 4953.1.1.19 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › RIFIN 0.60 47.0 4.08e-01 100.0% 54.4%
3934012 5081.1.1.4 ↗ alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DUF1751 0.59 45.0 3.68e-01 80.8% 86.0%
4597217 1050.1.1.0 ↗ alpha arrays › BID domain of Bartonella effector protein (Bep) › BID domain of Bartonella effector protein (Bep) › BID domain of Bartonella effector protein (Bep) 0.59 49.0 4.62e-01 100.0% 76.0%
3407357 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.57 40.0 3.49e-01 98.1% 48.1%
3288855 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 47.0 4.14e-01 94.2% 91.9%
3581261 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 34.0 3.62e-01 90.4% 69.5%
3627400 3615.1.1.0 ↗ alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.53 45.0 4.03e-01 94.2% 70.7%
4324499 3755.1.1.3 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM 0.51 35.0 3.12e-01 100.0% 50.3%
3179505 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.50 45.0 3.97e-01 100.0% 89.7%
4969891 5060.1.1.1 ↗ alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 0.50 42.0 3.33e-01 100.0% 43.1%
D2 medium residues 123-187_201-258_289-358
PDB
Domain cluster: rep: hypothetical_protein_3__YP_009345007__Wuhan_spider_virus_8__1923757__D1-105_147-200
D3 medium residues 259-288_359-432
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009342440__Wuhan_insect_virus_18__1923722__D388-416_481-565_595-607
D4 medium residues 437-542_556-577
PDB