←Back to structures
RNA-dependent_RNA_polymerase
Euk-VirWenling_narna-like_virus_7
RNA-dependent_RNA_polymerase__YP_009337166__Wenling_narna-like_virus_7__1923507
Identity
- Accession:
- YP_009337166 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
80.8
mean pLDDT
Cluster
View cluster (2 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 10-29_76-203
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2q9rA01 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.55 | 42.0 | 3.82e-01 | 79.1% | 100.0% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 34.0 | 4.14e-01 | 98.0% | 100.0% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3276380 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.56 | 42.0 | 3.18e-01 | 77.7% | 65.7% |
| 5068817 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 41.0 | 3.61e-01 | 77.0% | 78.2% |
| 5064484 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 39.0 | 3.57e-01 | 76.4% | 84.0% |
| 4977813 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.53 | 33.0 | 3.65e-01 | 77.0% | 78.9% |
D2
medium
residues 207-270_343-379_424-482
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009333153__Beihai_narna-like_virus_14__1922441__D77-145_426-451_481-543
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w53A00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.56 | 30.0 | 3.95e-01 | 80.6% | 97.6% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 217141 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.78 | 73.0 | 5.50e-01 | 100.0% | 68.1% |
| 3927049 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.74 | 68.0 | 5.01e-01 | 100.0% | 64.6% |
D3
medium
residues 271-342
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5dcaA11 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.69 | 47.0 | 4.16e-01 | 70.8% | 53.3% |
| 4cc9B00 | 1.20.5.4730 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 49.0 | 4.43e-01 | 76.4% | 60.2% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.68 | 47.0 | 4.34e-01 | 72.2% | 82.4% |
| 3o60A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 44.0 | 3.33e-01 | 73.6% | 27.5% |
| 2hg2A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.65 | 45.0 | 3.01e-01 | 73.6% | 18.2% |
| 1d0cA03 | 3.90.1230.10 | Alpha Beta › Alpha-Beta Complex › Bovine Endothelial Nitric Oxide Synthase Heme Domain; Chain: A,domain 3 › Nitric Oxide Synthase; Chain A, domain 3 | 0.64 | 46.0 | 4.34e-01 | 76.4% | 65.2% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.64 | 48.0 | 4.42e-01 | 80.6% | 82.1% |
| 3vz3A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.63 | 44.0 | 3.02e-01 | 73.6% | 20.5% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.61 | 45.0 | 4.22e-01 | 77.8% | 70.6% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.60 | 39.0 | 3.80e-01 | 75.0% | 59.3% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.59 | 45.0 | 4.30e-01 | 95.8% | 69.0% |
| 1xvpB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.56 | 46.0 | 3.27e-01 | 95.8% | 63.8% |
| 2oxlA00 | 1.20.5.5260 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 34.0 | 3.61e-01 | 97.2% | 72.6% |
| 2lpbA00 | 1.10.287.2920 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 41.0 | 3.98e-01 | 86.1% | 91.4% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.51 | 44.0 | 3.32e-01 | 93.1% | 64.5% |
| 3sp1A02 | 1.20.120.1910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cysteine-tRNA ligase, C-terminal anti-codon recognition domain | 0.51 | 38.0 | 3.12e-01 | 81.9% | 50.3% |
| 1fadA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.51 | 39.0 | 3.62e-01 | 84.7% | 96.8% |
| 4azcA02 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.50 | 28.0 | 3.03e-01 | 73.6% | 64.4% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3342961 | 4974.1.1.1 ↗ | alpha bundles › CRISPR-Cas system first helical domain › CRISPR-Cas system first helical domain › CRISPR-Cas system RNase C2c2 first helical domain › DUF4378 | 0.69 | 51.0 | 4.22e-01 | 79.2% | 96.9% |
| 3868871 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.66 | 51.0 | 3.75e-01 | 86.1% | 30.2% |
| 4031733 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.63 | 46.0 | 3.94e-01 | 77.8% | 71.3% |
| 3726041 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.62 | 47.0 | 4.32e-01 | 80.6% | 75.8% |
| 3878682 | 11.12.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD | 0.61 | 38.0 | 2.64e-01 | 79.2% | 21.9% |
| 3518918 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.60 | 41.0 | 4.13e-01 | 72.2% | 80.0% |
| 4663861 | 5069.1.3.78 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › MIS13 | 0.60 | 41.0 | 3.97e-01 | 70.8% | 63.7% |
| 3740688 | 7076.1.1.0 ↗ | 0.59 | 44.0 | 4.37e-01 | 77.8% | 88.0% | |
| 4456480 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.59 | 45.0 | 4.36e-01 | 83.3% | 83.7% |
| 3294347 | 101.1.17.20 ↗ | alpha arrays › HTH › HTH › FF domain › DUF4378 | 0.59 | 41.0 | 3.52e-01 | 73.6% | 50.8% |
| 5025683 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 0.58 | 37.0 | 4.04e-01 | 70.8% | 83.6% |
| 3396076 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.57 | 39.0 | 3.88e-01 | 70.8% | 68.0% |
| 3223457 | 101.1.2.661 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_9, POLR3C_WHD | 0.57 | 43.0 | 2.83e-01 | 77.8% | 89.3% |
| 5060022 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.56 | 42.0 | 4.21e-01 | 79.2% | 81.3% |
| 3568856 | 198.1.1.1 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 | 0.56 | 40.0 | 3.82e-01 | 79.2% | 75.6% |
| 3587785 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 43.0 | 3.09e-01 | 83.3% | 88.4% |
| 5060146 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.54 | 40.0 | 4.18e-01 | 77.8% | 93.8% |
| 4981741 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.54 | 39.0 | 4.23e-01 | 76.4% | 91.7% |
| 4463756 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.53 | 38.0 | 3.85e-01 | 77.8% | 75.7% |
| 5044069 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.53 | 39.0 | 3.84e-01 | 79.2% | 78.8% |
| 4964803 | 2004.1.1.1220 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF26510 | 0.53 | 43.0 | 2.90e-01 | 87.5% | 33.3% |
| 5062727 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.52 | 41.0 | 4.17e-01 | 83.3% | 88.6% |
| 5068969 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.51 | 40.0 | 4.12e-01 | 83.3% | 90.0% |
| 5069174 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.51 | 38.0 | 4.04e-01 | 79.2% | 92.3% |
| 3681259 | 5058.1.1.57 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › V-SNARE | 0.50 | 40.0 | 3.76e-01 | 83.3% | 76.5% |
D4
medium
residues 380-423_483-502_520-582_610-620
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009342440__Wuhan_insect_virus_18__1923722__D388-416_481-565_595-607
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1gx5A03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.75 | 59.0 | 6.27e-01 | 81.9% | 100.0% |
| 4ol8A01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.74 | 57.0 | 5.78e-01 | 100.0% | 81.5% |
| 1lfpA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.71 | 38.0 | 5.12e-01 | 88.4% | 100.0% |
| 3vtiA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.70 | 42.0 | 4.98e-01 | 76.1% | 86.5% |
| 4mz0B05 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.69 | 36.0 | 4.85e-01 | 74.6% | 100.0% |
| 1mw7A03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.68 | 38.0 | 4.95e-01 | 79.0% | 100.0% |
| 7e6gA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.68 | 52.0 | 5.07e-01 | 79.0% | 86.6% |
| 4f67A01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 42.0 | 4.73e-01 | 79.0% | 80.2% |
| 1jqgA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.68 | 41.0 | 4.86e-01 | 71.7% | 90.1% |
| 1konA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.67 | 37.0 | 4.78e-01 | 83.3% | 97.3% |
| 2fgcA03 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.65 | 36.0 | 4.77e-01 | 72.5% | 98.7% |
| 1s48A04 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.65 | 50.0 | 5.49e-01 | 84.1% | 100.0% |
| 1vk8A00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 41.0 | 4.87e-01 | 79.7% | 95.7% |
| 3ui3A02 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 42.0 | 4.81e-01 | 79.7% | 92.9% |
| 1apsA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 41.0 | 4.77e-01 | 79.0% | 91.8% |
| 1yrxC01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 40.0 | 4.50e-01 | 79.7% | 83.7% |
| 2ia0B02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.62 | 42.0 | 4.84e-01 | 82.6% | 97.0% |
| 1yqhA00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 42.0 | 4.72e-01 | 80.4% | 90.4% |
| 1lxjA00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 42.0 | 4.81e-01 | 79.0% | 93.2% |
| 2dbbA02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.61 | 41.0 | 4.78e-01 | 83.3% | 98.9% |
| 2qyxB01 | 3.30.70.1360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › mj0159-like | 0.61 | 38.0 | 4.18e-01 | 83.3% | 78.0% |
| 3d68A01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.60 | 37.0 | 4.40e-01 | 71.7% | 92.4% |
| 3gqcC01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.59 | 45.0 | 4.52e-01 | 78.3% | 94.9% |
| 4dpoB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 41.0 | 4.65e-01 | 70.3% | 100.0% |
| 3c1mA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.59 | 45.0 | 4.24e-01 | 79.7% | 90.9% |
| 3hvwA00 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.59 | 50.0 | 4.79e-01 | 98.6% | 79.9% |
| 1weyA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.58 | 42.0 | 4.74e-01 | 77.5% | 99.0% |
| 5o6uB00 | 3.30.70.2540 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › CRISPR-associated endoribonuclease Cas6/Csy4 | 0.58 | 43.0 | 3.91e-01 | 76.8% | 100.0% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.57 | 44.0 | 4.15e-01 | 81.2% | 91.5% |
| 3tviA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.57 | 42.0 | 4.00e-01 | 76.1% | 88.1% |
| 1w1oA03 | 3.40.462.10 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › FAD-linked oxidases, C-terminal domain | 0.55 | 40.0 | 3.42e-01 | 75.4% | 96.9% |
| 1bccA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.55 | 38.0 | 3.36e-01 | 71.0% | 88.2% |
| 1ea0A01 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.55 | 42.0 | 2.98e-01 | 80.4% | 57.8% |
| 4kr6A01 | 3.30.2130.30 | Alpha Beta › 2-Layer Sandwich › VC0802-like › | 0.55 | 39.0 | 3.61e-01 | 71.7% | 91.8% |
| 1hr6B02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.55 | 38.0 | 3.33e-01 | 71.0% | 88.5% |
| 1mwqA00 | 3.30.70.1060 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel | 0.53 | 37.0 | 4.25e-01 | 79.0% | 100.0% |
| 6a95B00 | 2.30.130.120 | Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › | 0.52 | 23.0 | 3.38e-01 | 92.8% | 100.0% |
| 4djbA00 | 3.30.70.2870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 | 0.51 | 38.0 | 4.13e-01 | 79.0% | 100.0% |
| 1v9kA00 | 3.30.2350.10 | Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › Pseudouridine synthase | 0.51 | 39.0 | 3.36e-01 | 82.6% | 62.1% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4215184 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.74 | 39.0 | 5.31e-01 | 74.6% | 100.0% |
| 3810170 | 304.48.1.43 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mitovir_RNA_pol | 0.73 | 70.0 | 6.30e-01 | 100.0% | 98.3% |
| 4070496 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.72 | 40.0 | 5.30e-01 | 81.2% | 100.0% |
| 4658950 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.72 | 40.0 | 5.24e-01 | 88.4% | 100.0% |
| 3976720 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.72 | 38.0 | 5.09e-01 | 85.5% | 100.0% |
| 4231349 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.71 | 38.0 | 5.05e-01 | 86.2% | 100.0% |
| 4678773 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.71 | 39.0 | 5.08e-01 | 84.8% | 97.3% |
| 4295716 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.70 | 37.0 | 4.92e-01 | 79.0% | 100.0% |
| 4080161 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.69 | 38.0 | 5.00e-01 | 74.6% | 100.0% |
| 5445 | 304.117.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC | 0.68 | 38.0 | 4.95e-01 | 79.0% | 100.0% |
| 4156338 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.68 | 37.0 | 4.77e-01 | 85.5% | 96.0% |
| 3626328 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.67 | 39.0 | 5.04e-01 | 87.7% | 100.0% |
| 1107972 | 304.26.1.2 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Ykof | 0.67 | 42.0 | 4.91e-01 | 75.4% | 88.8% |
| 3941725 | 304.28.1.3 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD-TM1 | 0.66 | 40.0 | 4.92e-01 | 85.5% | 96.5% |
| 3260062 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.66 | 38.0 | 4.81e-01 | 79.0% | 98.8% |
| 5040129 | 304.26.1.1 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP | 0.65 | 44.0 | 5.18e-01 | 78.3% | 98.9% |
| 4940473 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.65 | 42.0 | 5.06e-01 | 84.1% | 100.0% |
| 4343880 | 304.28.1.2 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG | 0.65 | 40.0 | 4.90e-01 | 85.5% | 100.0% |
| 3929751 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.64 | 38.0 | 4.79e-01 | 79.7% | 100.0% |
| 4033471 | 304.26.1.1 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP | 0.64 | 42.0 | 4.97e-01 | 80.4% | 96.8% |
| 5009749 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.64 | 41.0 | 4.87e-01 | 81.9% | 97.8% |
| 3974171 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.63 | 40.0 | 4.83e-01 | 83.3% | 98.9% |
| 3934979 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.63 | 58.0 | 4.28e-01 | 98.6% | 42.4% |
| 4019157 | 304.26.1.1 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP | 0.63 | 43.0 | 4.82e-01 | 79.7% | 89.8% |
| 5060355 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 42.0 | 4.93e-01 | 71.7% | 100.0% |
| 5012335 | 304.4.1.29 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 | 0.62 | 43.0 | 4.83e-01 | 82.6% | 94.3% |
| 3937455 | 304.7.1.1 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 | 0.62 | 38.0 | 4.53e-01 | 78.3% | 93.3% |
| 3968263 | 304.9.1.8 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › DbpA | 0.62 | 37.0 | 4.59e-01 | 76.1% | 97.6% |
| 4682115 | 304.28.1.4 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st | 0.61 | 40.0 | 4.76e-01 | 70.3% | 100.0% |
| 3290316 | 304.9.1.8 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › DbpA | 0.61 | 38.0 | 4.61e-01 | 73.2% | 100.0% |
| 4024398 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.61 | 39.0 | 4.69e-01 | 79.0% | 98.9% |
| 3949119 | 304.48.1.48 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 | 0.61 | 52.0 | 4.89e-01 | 100.0% | 77.0% |
| 3958034 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.60 | 36.0 | 4.39e-01 | 71.7% | 94.1% |
| 3512066 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.60 | 54.0 | 5.11e-01 | 97.1% | 85.5% |
| 3323407 | 304.126.1.2 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V-ATPase_C | 0.60 | 39.0 | 4.31e-01 | 92.0% | 84.8% |
| 3784530 | 304.126.1.2 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V-ATPase_C | 0.59 | 38.0 | 3.03e-01 | 70.3% | 32.2% |
| 3581464 | 304.9.1.10 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Calcipressin | 0.59 | 41.0 | 4.24e-01 | 79.7% | 75.8% |
| 3922306 | 4323.1.1.2 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V-ATPase_C | 0.59 | 39.0 | 3.06e-01 | 76.1% | 31.7% |
| 4024918 | 304.17.1.2 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN | 0.59 | 38.0 | 4.40e-01 | 84.1% | 94.7% |
| 3578563 | 304.126.1.2 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V-ATPase_C | 0.59 | 36.0 | 4.07e-01 | 70.3% | 80.0% |
| 4967978 | 304.9.1.8 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › DbpA | 0.58 | 37.0 | 4.21e-01 | 79.7% | 87.9% |
| 4980945 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.58 | 43.0 | 4.79e-01 | 80.4% | 100.0% |
| 4081916 | 304.33.1.1 ↗ | a+b two layers › Alpha-beta plaits › CheY-binding domain of CheA › CheY-binding domain of CheA › P2 | 0.57 | 43.0 | 4.67e-01 | 81.9% | 98.2% |
| 3273510 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 42.0 | 2.72e-01 | 81.9% | 50.6% |
| 5024074 | 304.55.2.0 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like | 0.53 | 41.0 | 3.69e-01 | 81.9% | 60.5% |
D5
medium
residues 621-672
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zzmA00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.65 | 51.0 | 3.31e-01 | 90.4% | 29.7% |
| 3nowA02 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.53 | 44.0 | 2.65e-01 | 96.2% | 11.9% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 41.0 | 3.37e-01 | 98.1% | 68.8% |
| 1m3qA02 | 1.10.1670.10 | Mainly Alpha › Orthogonal Bundle › Endonuclease Iii, domain 2 › Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) | 0.51 | 40.0 | 3.67e-01 | 98.1% | 82.5% |
D6
medium
residues 673-745_811-858
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 32.0 | 3.46e-01 | 80.2% | 69.0% |
D7
medium
residues 746-810
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8amqA02 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.62 | 48.0 | 2.95e-01 | 83.1% | 28.0% |
| 2hzdA00 | 6.10.20.40 | Special › Helix non-globular › Arc Repressor Mutant, subunit A › TEA/ATTS domain | 0.62 | 39.0 | 3.68e-01 | 84.6% | 51.2% |
| 1mzhA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.59 | 40.0 | 2.82e-01 | 72.3% | 86.2% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.56 | 40.0 | 3.13e-01 | 78.5% | 98.1% |
| 4uhwA09 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.55 | 36.0 | 3.20e-01 | 81.5% | 45.8% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.54 | 38.0 | 3.53e-01 | 73.8% | 69.5% |
| 7pb9A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 33.0 | 3.25e-01 | 78.5% | 57.4% |
| 2wadB03 | 1.10.10.1230 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Penicillin-binding protein, N-terminal non-catalytic domain, head sub-domain | 0.53 | 37.0 | 3.39e-01 | 100.0% | 53.8% |
| 3kraC00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 45.0 | 3.04e-01 | 100.0% | 99.3% |
| 4z5qA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 43.0 | 2.79e-01 | 96.9% | 66.7% |
| 1yb1B01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 42.0 | 2.91e-01 | 92.3% | 38.7% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.51 | 44.0 | 3.05e-01 | 95.4% | 81.9% |
| 3khkB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.51 | 44.0 | 3.37e-01 | 100.0% | 50.3% |
| 2e5vA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.50 | 41.0 | 2.70e-01 | 87.7% | 47.7% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3706130 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.62 | 50.0 | 4.49e-01 | 92.3% | 64.2% |
| 3958047 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.59 | 45.0 | 4.34e-01 | 84.6% | 72.0% |
| 3782200 | 3923.1.1.1 ↗ | alpha bundles › Mitotic chromosome determinant-related protein N-terminal domain › Mitotic chromosome determinant-related protein N-terminal domain › Mitotic chromosome determinant-related protein N-terminal domain › Rad21_Rec8_N | 0.56 | 40.0 | 3.67e-01 | 75.4% | 63.5% |
| 3951365 | 4018.1.1.2 ↗ | a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P | 0.56 | 48.0 | 3.67e-01 | 98.5% | 73.8% |
| 3599181 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.55 | 45.0 | 2.96e-01 | 89.2% | 79.3% |
| 3476239 | 4156.1.1.3 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › DSHCT | 0.55 | 44.0 | 3.19e-01 | 89.2% | 31.4% |
| 3187391 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.53 | 45.0 | 3.09e-01 | 96.9% | 26.9% |
| 3458940 | 101.1.10.38 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF247 | 0.52 | 45.0 | 3.56e-01 | 96.9% | 64.3% |
| 4026897 | 1008.1.1.0 ↗ | alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain | 0.52 | 44.0 | 3.13e-01 | 100.0% | 43.1% |
| 5015062 | 7523.1.1.3 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 | 0.51 | 45.0 | 3.01e-01 | 100.0% | 41.3% |
| 3783116 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 36.0 | 3.40e-01 | 89.2% | 62.5% |