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RNA-dependent_RNA_polymerase
Euk-VirBeihai_weivirus-like_virus_12
RNA-dependent_RNA_polymerase__YP_009337183__Beihai_weivirus-like_virus_12__1922741
Identity
- Accession:
- YP_009337183 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
71.2
mean pLDDT
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 286-574_646-655
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.71 | 67.0 | 5.49e-01 | 98.3% | 80.2% |
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.71 | 43.0 | 5.49e-01 | 88.3% | 100.0% |
| 1mzgB00 | 3.90.1010.10 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.52 | 25.0 | 3.42e-01 | 74.6% | 89.5% |
| 1i17A00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.50 | 20.0 | 3.19e-01 | 81.3% | 96.3% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 217141 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.71 | 67.0 | 6.25e-01 | 98.3% | 97.5% |
| 1697857 | 304.48.1.30 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › CPV_RdRP_pol_dom | 0.67 | 63.0 | 6.04e-01 | 99.3% | 100.0% |
| 223786 | 304.48.1.16 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_4 | 0.64 | 60.0 | 5.90e-01 | 99.3% | 100.0% |
| 3918122 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.64 | 60.0 | 5.39e-01 | 99.3% | 91.6% |
| 3258406 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.64 | 59.0 | 4.76e-01 | 99.3% | 64.8% |
| 4236458 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.55 | 46.0 | 4.57e-01 | 87.6% | 94.7% |
| 3486967 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.54 | 19.0 | 2.65e-01 | 70.2% | 57.3% |
| 3267570 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.53 | 50.0 | 4.72e-01 | 100.0% | 98.0% |
| 5063176 | 1076.1.1.4 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › PrsW-protease | 0.51 | 26.0 | 3.09e-01 | 92.0% | 68.7% |
| 3250871 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.51 | 27.0 | 3.67e-01 | 76.9% | 100.0% |
D2
medium
residues 1-59_79-154_181-202
D3
medium
residues 575-645
Domain cluster:
representative
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qq6A01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.64 | 43.0 | 3.70e-01 | 70.4% | 88.8% |
| 2ob0C01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.57 | 45.0 | 3.58e-01 | 91.5% | 73.5% |
| 2x3gA00 | 3.30.70.1910 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 47.0 | 4.14e-01 | 98.6% | 64.7% |
| 3rghA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 40.0 | 3.67e-01 | 77.5% | 64.6% |
| 3ihlB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 42.0 | 3.01e-01 | 84.5% | 92.1% |
| 3en9A03 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.54 | 37.0 | 3.76e-01 | 73.2% | 94.5% |
| 2k3iA01 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 42.0 | 3.96e-01 | 84.5% | 75.3% |
| 3qjlA02 | 3.30.70.1900 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 44.0 | 3.82e-01 | 94.4% | 76.5% |
| 3wfoA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.54 | 42.0 | 3.35e-01 | 87.3% | 58.6% |
| 4alzA01 | 3.30.1340.30 | Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › | 0.54 | 40.0 | 4.28e-01 | 85.9% | 93.5% |
| 1attA01 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.53 | 41.0 | 3.36e-01 | 85.9% | 75.0% |
| 1wchA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.53 | 42.0 | 2.88e-01 | 94.4% | 64.3% |
| 3tebB00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.53 | 42.0 | 2.99e-01 | 94.4% | 61.7% |
| 1je0C00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.53 | 45.0 | 3.25e-01 | 100.0% | 83.3% |
| 1ywuA00 | 2.40.10.220 | Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains | 0.52 | 42.0 | 3.60e-01 | 94.4% | 83.2% |
| 1t6aA02 | 3.30.310.120 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Rbstp2229 like protein | 0.52 | 39.0 | 3.86e-01 | 87.3% | 88.5% |
| 4umgA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 38.0 | 3.41e-01 | 81.7% | 63.7% |
| 4cllA01 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.51 | 42.0 | 3.13e-01 | 97.2% | 41.9% |
| 2zwaA02 | 2.120.10.80 | Mainly Beta › 6 Propeller › Neuraminidase › Kelch-type beta propeller | 0.50 | 43.0 | 2.86e-01 | 98.6% | 61.3% |
| 2anrA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.50 | 36.0 | 3.55e-01 | 76.1% | 74.7% |
| 3upuA03 | 2.30.30.780 | Mainly Beta › Roll › SH3 type barrels. › | 0.50 | 38.0 | 3.17e-01 | 83.1% | 94.7% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5015118 | 218.1.1.2 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N | 0.63 | 43.0 | 3.72e-01 | 70.4% | 98.3% |
| 5012054 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.62 | 49.0 | 5.00e-01 | 87.3% | 90.0% |
| 4987228 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.62 | 44.0 | 3.40e-01 | 76.1% | 55.6% |
| 3265018 | 221.1.1.6 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA | 0.60 | 44.0 | 4.03e-01 | 78.9% | 82.1% |
| 3724051 | 6044.1.1.0 ↗ | a+b three layers › DUF1827-like › DUF1827-like › DUF1827-like | 0.60 | 51.0 | 4.54e-01 | 98.6% | 78.1% |
| 3263272 | 2484.1.1.66 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 | 0.58 | 41.0 | 3.32e-01 | 74.6% | 60.0% |
| 3701535 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.56 | 45.0 | 4.19e-01 | 88.7% | 74.4% |
| 3350473 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.56 | 40.0 | 4.08e-01 | 78.9% | 94.3% |
| 4984757 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.53 | 38.0 | 3.61e-01 | 78.9% | 66.7% |
| 4024042 | 223.2.1.31 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_2 | 0.53 | 38.0 | 2.87e-01 | 77.5% | 60.5% |
| 3958863 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.53 | 41.0 | 3.85e-01 | 85.9% | 70.5% |
| 3911275 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.52 | 42.0 | 2.72e-01 | 95.8% | 66.1% |
| 5010443 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.51 | 42.0 | 2.64e-01 | 95.8% | 29.2% |
| 3242105 | 207.1.1.81 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH | 0.51 | 43.0 | 3.17e-01 | 95.8% | 69.0% |
| 4182599 | 223.2.1.20 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Fuz_longin_1 | 0.51 | 36.0 | 2.76e-01 | 73.2% | 61.3% |
| 4027323 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.51 | 37.0 | 2.71e-01 | 81.7% | 74.5% |
| 3623124 | 3346.1.1.1 ↗ | a+b two layers › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › UfSP2_N | 0.51 | 41.0 | 3.08e-01 | 98.6% | 84.1% |
| 5007927 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.50 | 42.0 | 3.47e-01 | 94.4% | 88.7% |