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RNA-dependent_RNA_polymerase
Euk-VirBeihai_weivirus-like_virus_9
RNA-dependent_RNA_polymerase__YP_009337250__Beihai_weivirus-like_virus_9__1922756
Identity
- Accession:
- YP_009337250 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
82.8
mean pLDDT
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-153
D2
high
residues 680-834
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337047__Beihai_weivirus-like_virus_7__1922754__D604-746
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1t9kA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.57 | 33.0 | 3.48e-01 | 97.4% | 62.9% |
| 3q23A08 | 1.20.140.110 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.51 | 37.0 | 3.74e-01 | 73.5% | 98.1% |
D3
medium
residues 306-358_508-600
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.69 | 62.0 | 4.23e-01 | 97.9% | 67.8% |
| 2anrA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.51 | 24.0 | 3.25e-01 | 82.2% | 86.7% |
D4
medium
residues 359-447
Domain cluster:
rep: hypothetical_protein_2__YP_009333161__Hubei_tombus-like_virus_32__1923280__D105-190
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1l7aA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.59 | 45.0 | 3.10e-01 | 82.0% | 86.8% |
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.59 | 44.0 | 3.62e-01 | 100.0% | 41.5% |
| 5xoyB02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 31.0 | 2.90e-01 | 95.5% | 39.3% |
| 2zdiB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 32.0 | 3.12e-01 | 83.1% | 51.9% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3250871 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.60 | 52.0 | 4.42e-01 | 98.9% | 76.7% |
| 3474147 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 37.0 | 2.40e-01 | 70.8% | 57.9% |
| 3751719 | 295.1.1.3 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA | 0.52 | 36.0 | 3.60e-01 | 71.9% | 73.3% |
D5
medium
residues 601-673
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337183__Beihai_weivirus-like_virus_12__1922741__D575-645
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5h3hB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.57 | 45.0 | 3.17e-01 | 91.8% | 98.1% |
| 2pgeA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.57 | 41.0 | 3.51e-01 | 79.5% | 100.0% |
| 2il5A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.56 | 39.0 | 3.10e-01 | 74.0% | 52.5% |
| 3h04A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.56 | 44.0 | 3.11e-01 | 91.8% | 98.5% |
| 6l4lA02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.55 | 46.0 | 3.87e-01 | 97.3% | 98.5% |
| 2rrlA01 | 3.30.750.140 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.55 | 42.0 | 3.72e-01 | 86.3% | 63.5% |
| 4krgA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.54 | 42.0 | 3.00e-01 | 87.7% | 48.2% |
| 1xl7A02 | 3.30.559.70 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Choline/Carnitine o-acyltransferase, domain 2 | 0.54 | 41.0 | 2.78e-01 | 86.3% | 65.3% |
| 2anrA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.54 | 37.0 | 3.74e-01 | 74.0% | 70.7% |
| 1t6aA02 | 3.30.310.120 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Rbstp2229 like protein | 0.53 | 41.0 | 4.04e-01 | 86.3% | 85.9% |
| 7dpyB01 | 2.40.128.200 | Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor | 0.52 | 35.0 | 3.44e-01 | 83.6% | 62.7% |
| 2la7A01 | 2.40.128.270 | Mainly Beta › Beta Barrel › Lipocalin › | 0.52 | 37.0 | 3.21e-01 | 79.5% | 85.9% |
| 1y9lA00 | 2.40.128.230 | Mainly Beta › Beta Barrel › Lipocalin › Pilot protein MxiM | 0.51 | 37.0 | 3.32e-01 | 79.5% | 68.2% |
| 4kh9B02 | 2.60.40.1930 | Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain | 0.50 | 40.0 | 3.56e-01 | 90.4% | 64.6% |
| 7zvsB01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.50 | 39.0 | 3.58e-01 | 86.3% | 67.7% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4987228 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.63 | 44.0 | 3.41e-01 | 74.0% | 52.7% |
| 3033584 | 9.1.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin | 0.61 | 47.0 | 3.67e-01 | 86.3% | 89.4% |
| 3814194 | 327.7.1.8 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › Peptidase_M16_M | 0.60 | 43.0 | 4.17e-01 | 78.1% | 91.8% |
| 3499000 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.57 | 41.0 | 2.77e-01 | 76.7% | 79.7% |
| 4848452 | 135.1.1.1 ↗ | alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › G-alpha | 0.57 | 35.0 | 3.97e-01 | 79.5% | 91.8% |
| 4024042 | 223.2.1.31 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_2 | 0.55 | 40.0 | 3.05e-01 | 76.7% | 87.6% |
| 3998663 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.52 | 41.0 | 4.23e-01 | 93.2% | 95.7% |
| 4478350 | 218.1.1.2 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N | 0.52 | 38.0 | 3.28e-01 | 79.5% | 97.5% |
| 3263272 | 2484.1.1.66 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 | 0.52 | 44.0 | 3.62e-01 | 97.3% | 52.9% |
| 5036255 | 241.1.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone | 0.51 | 41.0 | 3.64e-01 | 93.2% | 74.8% |
| 3777334 | 9.1.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin | 0.51 | 43.0 | 3.45e-01 | 98.6% | 70.4% |
| 3281774 | 9.1.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META | 0.51 | 38.0 | 3.38e-01 | 82.2% | 91.8% |