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RNA-dependent_RNA_polymerase
Euk-VirChangjiang_narna-like_virus_1
RNA-dependent_RNA_polymerase__YP_009337331__Changjiang_narna-like_virus_1__1922776
Identity
- Accession:
- YP_009337331 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
67.7
mean pLDDT
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 57-148
Domain cluster:
representative
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 49.0 | 4.49e-01 | 72.8% | 100.0% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.69 | 51.0 | 4.19e-01 | 78.3% | 81.9% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.67 | 59.0 | 4.40e-01 | 100.0% | 70.7% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.66 | 59.0 | 4.56e-01 | 100.0% | 80.2% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 49.0 | 3.60e-01 | 81.5% | 48.8% |
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 39.0 | 4.25e-01 | 85.9% | 72.7% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.64 | 48.0 | 4.32e-01 | 79.3% | 57.8% |
| 2dofA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.64 | 35.0 | 3.65e-01 | 76.1% | 55.3% |
| 2c42A06 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.64 | 51.0 | 3.42e-01 | 88.0% | 36.4% |
| 1tf5A04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.64 | 57.0 | 4.60e-01 | 100.0% | 92.9% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.63 | 39.0 | 3.95e-01 | 78.3% | 62.9% |
| 3oo3A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.61 | 45.0 | 3.06e-01 | 79.3% | 55.8% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.61 | 47.0 | 4.46e-01 | 89.1% | 68.8% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.61 | 42.0 | 4.58e-01 | 77.2% | 89.3% |
| 1qgtB00 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.60 | 48.0 | 4.11e-01 | 84.8% | 72.7% |
| 6pnjL00 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.60 | 49.0 | 4.11e-01 | 89.1% | 59.6% |
| 2nsaA00 | 1.10.3120.10 | Mainly Alpha › Orthogonal Bundle › Trigger factor, domain 2 › Trigger factor, C-terminal domain | 0.59 | 43.0 | 3.53e-01 | 76.1% | 59.9% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 50.0 | 4.09e-01 | 91.3% | 75.6% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.59 | 49.0 | 3.71e-01 | 92.4% | 92.1% |
| 4fm3A00 | 1.20.1270.390 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 39.0 | 3.89e-01 | 100.0% | 65.3% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 43.0 | 4.31e-01 | 85.9% | 76.6% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 43.0 | 4.28e-01 | 92.4% | 74.2% |
| 4qgpB00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.57 | 45.0 | 4.36e-01 | 94.6% | 74.8% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.57 | 40.0 | 3.61e-01 | 73.9% | 86.5% |
| 2qwtA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 45.0 | 3.72e-01 | 85.9% | 49.1% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 47.0 | 4.19e-01 | 91.3% | 94.7% |
| 2x1dA02 | 1.10.10.2120 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.56 | 41.0 | 4.53e-01 | 94.6% | 98.6% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 42.0 | 3.78e-01 | 85.9% | 57.8% |
| 1pw4A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 44.0 | 3.41e-01 | 88.0% | 93.3% |
| 2zs0A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 37.0 | 3.26e-01 | 84.8% | 45.7% |
| 3bjdA01 | 1.10.1240.20 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain | 0.55 | 32.0 | 3.31e-01 | 77.2% | 60.2% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 47.0 | 3.80e-01 | 95.7% | 69.0% |
| 3smtA02 | 3.90.1420.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain | 0.53 | 42.0 | 3.59e-01 | 90.2% | 67.7% |
| 3qbrX00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.50 | 38.0 | 3.21e-01 | 81.5% | 90.7% |
ECOD (62)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3488340 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.68 | 48.0 | 4.49e-01 | 81.5% | 59.1% |
| 5028473 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.67 | 46.0 | 4.27e-01 | 70.7% | 55.7% |
| 4583117 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.67 | 49.0 | 4.48e-01 | 89.1% | 58.3% |
| 3961347 | 150.5.1.53 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE | 0.67 | 48.0 | 4.99e-01 | 75.0% | 92.9% |
| 3782074 | 604.5.1.47 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ATG2_CAD | 0.66 | 54.0 | 4.71e-01 | 91.3% | 58.6% |
| 4527504 | 150.5.1.122 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › ATG2_CAD | 0.66 | 59.0 | 5.08e-01 | 98.9% | 90.3% |
| 4992256 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 51.0 | 4.99e-01 | 89.1% | 76.8% |
| 3699525 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.66 | 46.0 | 4.24e-01 | 72.8% | 58.3% |
| 3626648 | 5076.2.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › EI24 | 0.65 | 55.0 | 4.18e-01 | 98.9% | 37.8% |
| 3471905 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 49.0 | 3.91e-01 | 80.4% | 87.4% |
| 4032960 | 5050.1.1.21 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 | 0.65 | 46.0 | 3.39e-01 | 73.9% | 79.6% |
| 4192211 | 192.29.1.159 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › ATG2_CAD | 0.65 | 55.0 | 5.05e-01 | 93.5% | 83.3% |
| 3939450 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.65 | 50.0 | 3.39e-01 | 82.6% | 57.4% |
| 4954843 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.64 | 48.0 | 4.78e-01 | 85.9% | 75.8% |
| 5044416 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 49.0 | 3.91e-01 | 82.6% | 75.8% |
| 3241279 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.64 | 53.0 | 4.45e-01 | 90.2% | 99.4% |
| 4459896 | 622.4.1.1 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 | 0.64 | 49.0 | 4.59e-01 | 84.8% | 65.8% |
| 3799927 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.63 | 56.0 | 4.15e-01 | 96.7% | 79.6% |
| 3221766 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 47.0 | 4.50e-01 | 88.0% | 68.6% |
| 3596042 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.63 | 48.0 | 4.19e-01 | 84.8% | 54.8% |
| 2576218 | 150.1.1.84 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › IMEF_Flp | 0.62 | 48.0 | 4.23e-01 | 83.7% | 95.7% |
| 3915514 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 54.0 | 4.86e-01 | 94.6% | 90.4% |
| 3346653 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.62 | 42.0 | 4.05e-01 | 84.8% | 61.0% |
| 4987972 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.62 | 55.0 | 4.03e-01 | 100.0% | 72.3% |
| 4069591 | 1079.1.1.11 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › NicO | 0.62 | 54.0 | 4.05e-01 | 94.6% | 78.1% |
| 3581267 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 43.0 | 4.41e-01 | 84.8% | 76.7% |
| 3423775 | 601.16.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 | 0.61 | 45.0 | 3.82e-01 | 79.3% | 67.7% |
| 5057068 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.61 | 48.0 | 4.73e-01 | 87.0% | 89.0% |
| 3928099 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 54.0 | 3.89e-01 | 97.8% | 94.1% |
| 4545540 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.60 | 42.0 | 3.22e-01 | 73.9% | 80.0% |
| 3225376 | 601.1.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 | 0.59 | 49.0 | 4.19e-01 | 98.9% | 56.0% |
| 3693444 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.59 | 51.0 | 4.24e-01 | 98.9% | 63.5% |
| 3254975 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.59 | 46.0 | 4.33e-01 | 85.9% | 67.8% |
| 3252622 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 43.0 | 4.30e-01 | 85.9% | 74.7% |
| 3190632 | 633.21.1.45 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › TMD0_ABC | 0.59 | 52.0 | 4.02e-01 | 97.8% | 75.6% |
| 3212211 | 5001.1.1.25 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sru | 0.59 | 52.0 | 3.53e-01 | 97.8% | 81.2% |
| 3578804 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.58 | 50.0 | 3.69e-01 | 98.9% | 41.1% |
| 56672 | 150.3.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine | 0.58 | 51.0 | 4.36e-01 | 96.7% | 95.9% |
| 3829206 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.58 | 41.0 | 4.26e-01 | 95.7% | 81.2% |
| 4033272 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.58 | 48.0 | 4.45e-01 | 100.0% | 71.7% |
| 4413536 | 604.5.1.67 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › DOG1 | 0.58 | 52.0 | 3.89e-01 | 98.9% | 47.9% |
| 3932144 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.57 | 49.0 | 4.60e-01 | 95.7% | 100.0% |
| 3928846 | 7022.1.1.0 ↗ | alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein | 0.57 | 49.0 | 4.35e-01 | 97.8% | 86.4% |
| 5003109 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.57 | 49.0 | 3.68e-01 | 94.6% | 76.9% |
| 3931307 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.57 | 47.0 | 4.08e-01 | 91.3% | 93.1% |
| 3580347 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 43.0 | 4.19e-01 | 85.9% | 73.3% |
| 3789449 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.55 | 46.0 | 4.63e-01 | 91.3% | 97.9% |
| 4030401 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.55 | 49.0 | 4.04e-01 | 100.0% | 56.4% |
| 3926870 | 5050.1.1.32 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Acatn | 0.55 | 46.0 | 3.44e-01 | 95.7% | 44.4% |
| 4261674 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.55 | 47.0 | 3.28e-01 | 96.7% | 31.3% |
| 4568331 | 4070.1.1.2 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 | 0.55 | 41.0 | 3.16e-01 | 82.6% | 67.1% |
| 3517672 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.54 | 48.0 | 4.08e-01 | 96.7% | 82.7% |
| 3244093 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.54 | 48.0 | 3.79e-01 | 100.0% | 94.5% |
| 3247271 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 47.0 | 3.38e-01 | 97.8% | 87.0% |
| 4204463 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.54 | 41.0 | 3.30e-01 | 80.4% | 75.0% |
| 3181501 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 45.0 | 3.52e-01 | 94.6% | 52.6% |
| 3211513 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.54 | 46.0 | 3.20e-01 | 97.8% | 83.3% |
| 3931883 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.53 | 46.0 | 4.36e-01 | 95.7% | 92.7% |
| 3589614 | 601.1.2.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar | 0.53 | 43.0 | 3.98e-01 | 97.8% | 68.3% |
| 4148010 | 632.1.1.24 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DAGK_prokar | 0.53 | 43.0 | 3.97e-01 | 98.9% | 68.0% |
| 4000935 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.52 | 44.0 | 3.48e-01 | 98.9% | 56.2% |
| 5050983 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.51 | 44.0 | 3.44e-01 | 98.9% | 83.6% |
D2
medium
residues 149-229
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.75 | 39.0 | 3.85e-01 | 100.0% | 47.1% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.67 | 38.0 | 3.62e-01 | 100.0% | 47.4% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.65 | 38.0 | 3.72e-01 | 100.0% | 51.1% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.64 | 39.0 | 3.52e-01 | 100.0% | 43.0% |
| 6qelA01 | 1.10.860.10 | Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A | 0.63 | 36.0 | 2.99e-01 | 100.0% | 30.5% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 43.0 | 3.39e-01 | 100.0% | 38.2% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 39.0 | 3.60e-01 | 100.0% | 52.5% |
| 1rrmA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.60 | 41.0 | 3.10e-01 | 71.6% | 91.5% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.59 | 42.0 | 4.78e-01 | 100.0% | 100.0% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.59 | 42.0 | 3.71e-01 | 100.0% | 52.7% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 36.0 | 3.19e-01 | 97.5% | 41.9% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 41.0 | 3.41e-01 | 100.0% | 43.5% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 51.0 | 3.94e-01 | 100.0% | 99.5% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 50.0 | 3.58e-01 | 100.0% | 83.1% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 49.0 | 4.17e-01 | 100.0% | 74.1% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.54 | 47.0 | 4.28e-01 | 100.0% | 85.1% |
| 4c0nA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 40.0 | 3.36e-01 | 80.2% | 73.3% |
| 3lcnB00 | 1.10.340.40 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain | 0.53 | 35.0 | 3.31e-01 | 82.7% | 55.7% |
| 6f7hA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.53 | 43.0 | 3.09e-01 | 90.1% | 74.9% |
| 8gccA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.53 | 46.0 | 4.30e-01 | 100.0% | 79.8% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 36.0 | 3.57e-01 | 70.4% | 95.2% |
| 1ngkB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 39.0 | 3.42e-01 | 80.2% | 85.8% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 45.0 | 4.07e-01 | 100.0% | 75.7% |
| 3cuxA02 | 1.20.1220.12 | Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III | 0.51 | 39.0 | 3.46e-01 | 82.7% | 97.5% |
| 1qlbA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.51 | 38.0 | 3.40e-01 | 80.2% | 74.6% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.50 | 45.0 | 3.39e-01 | 100.0% | 67.5% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3999930 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.76 | 45.0 | 4.00e-01 | 100.0% | 43.6% |
| 3547209 | 192.15.1.204 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2678 | 0.72 | 41.0 | 3.84e-01 | 100.0% | 46.0% |
| 5074225 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.70 | 44.0 | 4.22e-01 | 100.0% | 56.7% |
| 3227781 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.63 | 40.0 | 3.59e-01 | 100.0% | 47.3% |
| 4939727 | 5076.2.1.3 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF4013 | 0.62 | 38.0 | 2.85e-01 | 96.3% | 23.8% |
| 4393454 | 632.15.1.6 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 | 0.62 | 38.0 | 3.54e-01 | 100.0% | 50.0% |
| 3990094 | 5086.1.1.94 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD | 0.61 | 48.0 | 3.83e-01 | 100.0% | 41.2% |
| 3212811 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 54.0 | 4.60e-01 | 100.0% | 90.8% |
| 5022672 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.60 | 42.0 | 3.98e-01 | 72.8% | 96.8% |
| 3182158 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 53.0 | 3.82e-01 | 100.0% | 88.9% |
| 5028471 | 5076.2.1.3 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF4013 | 0.59 | 36.0 | 2.78e-01 | 96.3% | 24.7% |
| 4026469 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 48.0 | 3.58e-01 | 100.0% | 89.8% |
| 5029782 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.55 | 40.0 | 3.92e-01 | 77.8% | 94.4% |
| 5007002 | 1075.1.1.67 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › 12TM_1 | 0.55 | 46.0 | 3.56e-01 | 95.1% | 66.7% |
| 3481387 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.55 | 37.0 | 3.34e-01 | 71.6% | 71.7% |
| 4938198 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.54 | 35.0 | 3.48e-01 | 79.0% | 60.0% |
| 4671536 | 3718.1.1.1 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT | 0.53 | 37.0 | 3.55e-01 | 72.8% | 86.3% |
| 3436259 | 632.15.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › Rx_N | 0.53 | 35.0 | 3.07e-01 | 100.0% | 45.8% |
| 4934286 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.52 | 46.0 | 3.97e-01 | 100.0% | 97.7% |
| 3509228 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 42.0 | 3.42e-01 | 93.8% | 98.9% |
| 3233475 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.50 | 43.0 | 3.61e-01 | 100.0% | 100.0% |
| 3594664 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.50 | 42.0 | 2.66e-01 | 100.0% | 19.5% |
| 4029940 | 604.5.1.44 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › EMC6 | 0.50 | 34.0 | 3.28e-01 | 98.8% | 60.0% |
| 4012813 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 42.0 | 3.23e-01 | 96.3% | 96.0% |
D3
medium
residues 230-252_392-411_511-533
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cqgA02 | 3.10.10.20 | Alpha Beta › Roll › HIV Type 1 Reverse Transcriptase; Chain A, domain 1 › | 0.69 | 58.0 | 5.69e-01 | 95.5% | 97.2% |
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.64 | 51.0 | 3.76e-01 | 87.9% | 98.9% |
| 1r94A00 | 2.60.300.12 | Mainly Beta › Sandwich › Hypothetical Protein Aq_1857; Chain: A; › HesB-like domain | 0.54 | 38.0 | 3.36e-01 | 74.2% | 91.8% |
| 4mh4A02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.54 | 46.0 | 4.15e-01 | 98.5% | 100.0% |
| 1x0gA00 | 2.60.300.12 | Mainly Beta › Sandwich › Hypothetical Protein Aq_1857; Chain: A; › HesB-like domain | 0.50 | 37.0 | 3.20e-01 | 78.8% | 78.4% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3514826 | 389.1.1.0 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin | 0.58 | 34.0 | 3.97e-01 | 84.8% | 84.4% |
| None | — | 0.56 | 40.0 | 2.69e-01 | 77.3% | 36.1% | |
| 3874464 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 40.0 | 2.59e-01 | 78.8% | 75.8% |
| 4606082 | 812.1.1.1 ↗ | a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE | 0.55 | 41.0 | 4.45e-01 | 89.4% | 98.2% |
| 3695700 | 80.1.1.1 ↗ | beta complex topology › HesB-like domain › HesB-like domain › HesB-like domain › Fe-S_biosyn | 0.52 | 38.0 | 3.05e-01 | 78.8% | 87.4% |
| 3193439 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.51 | 39.0 | 2.60e-01 | 84.8% | 69.3% |
| 4015998 | 10.12.1.107 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › PF27522 | 0.50 | 38.0 | 2.83e-01 | 86.4% | 84.9% |
D4
medium
residues 437-477_534-640
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337087__Hubei_narna-like_virus_4__1922958__D375-415_481-588
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1gx5A03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.75 | 58.0 | 6.32e-01 | 81.8% | 96.7% |
| 1khvA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.73 | 58.0 | 6.15e-01 | 82.4% | 98.5% |
| 3h5xA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.72 | 55.0 | 6.10e-01 | 98.0% | 100.0% |
| 1konA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.72 | 36.0 | 4.85e-01 | 81.1% | 93.3% |
| 1ra6A02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.70 | 49.0 | 5.64e-01 | 77.0% | 100.0% |
| 5jxsA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.69 | 60.0 | 6.12e-01 | 99.3% | 95.8% |
| 3trgA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 39.0 | 4.78e-01 | 70.3% | 90.4% |
| 2hiyA01 | 3.30.70.1280 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SP0830-like domains | 0.66 | 40.0 | 4.99e-01 | 82.4% | 100.0% |
| 4oj3B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 40.0 | 4.83e-01 | 79.7% | 92.6% |
| 1vk8A00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 41.0 | 5.00e-01 | 79.1% | 100.0% |
| 2cqhA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.60 | 34.0 | 4.16e-01 | 85.8% | 87.1% |
| 8d8lF01 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.60 | 44.0 | 4.81e-01 | 77.0% | 100.0% |
| 2kviA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.60 | 32.0 | 4.26e-01 | 70.3% | 100.0% |
| 4y6iA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 38.0 | 4.46e-01 | 77.7% | 92.2% |
| 1p50A02 | 3.30.590.10 | Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain | 0.58 | 46.0 | 3.85e-01 | 84.5% | 80.0% |
| 4hvmB01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.58 | 42.0 | 3.92e-01 | 75.7% | 89.9% |
| 3pjxA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.57 | 50.0 | 4.72e-01 | 98.6% | 77.3% |
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.56 | 46.0 | 3.76e-01 | 85.8% | 75.9% |
| 5k9fA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 38.0 | 4.41e-01 | 81.1% | 99.0% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.56 | 45.0 | 4.33e-01 | 84.5% | 94.5% |
| 1rjjA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 39.0 | 4.47e-01 | 74.3% | 97.3% |
| 3gqcC01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.55 | 45.0 | 4.67e-01 | 84.5% | 97.1% |
| 3qjlA01 | 3.30.70.1890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 41.0 | 4.53e-01 | 79.7% | 100.0% |
| 3aawA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.54 | 43.0 | 4.17e-01 | 83.1% | 89.7% |
| 5wpjA02 | 3.30.70.420 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain | 0.54 | 38.0 | 4.35e-01 | 72.3% | 100.0% |
| 1q2lA03 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.54 | 43.0 | 3.75e-01 | 85.1% | 83.5% |
| 2okqB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 39.0 | 4.29e-01 | 81.1% | 96.6% |
| 1zj8A02 | 3.90.480.10 | Alpha Beta › Alpha-Beta Complex › Sulfite Reductase Hemoprotein; domain 2 › Sulfite Reductase Hemoprotein;Domain 2 | 0.52 | 37.0 | 3.67e-01 | 72.3% | 96.7% |
| 1vk3A01 | 3.90.650.10 | Alpha Beta › Alpha-Beta Complex › Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 › PurM-like C-terminal domain | 0.52 | 44.0 | 4.05e-01 | 90.5% | 88.8% |
| 3qpiA00 | 3.30.70.3420 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 40.0 | 3.88e-01 | 83.8% | 100.0% |
| 1ybtB00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.51 | 44.0 | 4.20e-01 | 92.6% | 89.5% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5040118 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.81 | 39.0 | 5.68e-01 | 72.3% | 100.0% |
| 3784880 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.78 | 45.0 | 5.84e-01 | 70.9% | 100.0% |
| 4678773 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.71 | 36.0 | 4.88e-01 | 80.4% | 94.7% |
| 3939861 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 55.0 | 6.08e-01 | 95.9% | 100.0% |
| 3260113 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 50.0 | 5.76e-01 | 74.3% | 100.0% |
| 4590927 | 304.28.1.2 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG | 0.69 | 42.0 | 5.27e-01 | 70.3% | 100.0% |
| 3315278 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.68 | 47.0 | 5.13e-01 | 80.4% | 84.0% |
| 4983446 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.68 | 47.0 | 5.51e-01 | 79.1% | 100.0% |
| 5029718 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.67 | 62.0 | 4.67e-01 | 100.0% | 57.1% |
| 3960648 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.66 | 61.0 | 4.74e-01 | 98.6% | 70.2% |
| 3236725 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.66 | 61.0 | 5.03e-01 | 100.0% | 77.3% |
| 3258201 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.66 | 55.0 | 4.70e-01 | 88.5% | 97.4% |
| 4365193 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.66 | 60.0 | 4.70e-01 | 98.6% | 77.1% |
| 4014158 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.66 | 61.0 | 4.82e-01 | 100.0% | 70.5% |
| 4497954 | 304.48.1.73 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N | 0.66 | 54.0 | 4.17e-01 | 85.8% | 55.2% |
| 3836503 | 304.7.1.2 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 | 0.65 | 40.0 | 4.95e-01 | 83.1% | 100.0% |
| 4989811 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.65 | 45.0 | 5.23e-01 | 81.1% | 100.0% |
| 3739302 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.65 | 45.0 | 4.09e-01 | 70.9% | 83.1% |
| 3483524 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.65 | 58.0 | 4.51e-01 | 95.9% | 59.7% |
| 2512867 | 304.51.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related | 0.64 | 43.0 | 4.81e-01 | 78.4% | 87.8% |
| 3957166 | 304.43.1.0 ↗ | a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 | 0.64 | 41.0 | 4.95e-01 | 70.9% | 100.0% |
| 3601834 | 304.48.1.6 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A | 0.64 | 45.0 | 5.11e-01 | 80.4% | 96.4% |
| 4928490 | 304.48.1.22 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III | 0.63 | 50.0 | 4.13e-01 | 81.8% | 78.8% |
| 3661726 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.63 | 40.0 | 4.74e-01 | 82.4% | 94.0% |
| 4254800 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.62 | 41.0 | 4.84e-01 | 73.6% | 99.0% |
| 3272032 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.62 | 38.0 | 4.65e-01 | 78.4% | 100.0% |
| 4883269 | 304.51.1.5 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Csy4 | 0.62 | 39.0 | 4.75e-01 | 71.6% | 100.0% |
| 3291429 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.60 | 49.0 | 4.78e-01 | 94.6% | 79.4% |
| 3016421 | 304.4.1.5 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Dyp_perox_N | 0.60 | 41.0 | 4.36e-01 | 70.3% | 97.0% |
| 4028494 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.59 | 37.0 | 4.28e-01 | 87.8% | 87.6% |
| 4964275 | 304.57.1.1 ↗ | a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 | 0.59 | 42.0 | 4.59e-01 | 73.0% | 94.2% |
| 4993060 | 304.55.2.1 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp | 0.59 | 49.0 | 4.90e-01 | 87.8% | 90.7% |
| 3388863 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.58 | 40.0 | 4.17e-01 | 84.5% | 74.3% |
| 3735153 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.58 | 41.0 | 4.57e-01 | 71.6% | 100.0% |
| 3496888 | 309.1.1.12 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PreP_C | 0.58 | 43.0 | 3.42e-01 | 75.7% | 89.0% |
| 4366330 | 304.20.1.5 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f | 0.58 | 46.0 | 4.48e-01 | 84.5% | 100.0% |
| 4447424 | 304.55.1.26 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › RepSA | 0.58 | 52.0 | 4.22e-01 | 98.0% | 72.7% |
| 3947199 | 304.126.1.5 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › PrmA | 0.58 | 38.0 | 4.58e-01 | 73.0% | 100.0% |
| 4926825 | 304.4.1.2 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase | 0.57 | 39.0 | 4.59e-01 | 77.7% | 99.0% |
| None | — | 0.56 | 47.0 | 3.92e-01 | 89.2% | 73.3% | |
| 3416685 | 304.28.1.37 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › DUF4780 | 0.55 | 37.0 | 4.33e-01 | 77.0% | 100.0% |
| 3272117 | 304.48.1.4 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc | 0.55 | 50.0 | 3.48e-01 | 98.6% | 78.1% |
| 3260596 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.55 | 35.0 | 4.22e-01 | 73.6% | 100.0% |
| 3487835 | 309.1.1.0 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase | 0.55 | 46.0 | 2.83e-01 | 91.9% | 77.9% |
| 3614494 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 45.0 | 3.77e-01 | 89.2% | 68.1% |
| 3507411 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.54 | 38.0 | 4.24e-01 | 89.9% | 95.5% |
| 4649093 | 304.48.1.4 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc | 0.54 | 46.0 | 4.19e-01 | 89.2% | 93.2% |
| 3805333 | 331.18.1.4 ↗ | a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › COR-B | 0.53 | 48.0 | 4.37e-01 | 99.3% | 88.5% |
| 3332318 | 331.2.1.11 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › COR-B | 0.53 | 48.0 | 4.41e-01 | 99.3% | 92.1% |
| None | — | 0.53 | 42.0 | 4.17e-01 | 83.8% | 87.6% | |
| 3785779 | 604.3.1.11 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 | 0.52 | 41.0 | 3.47e-01 | 84.5% | 90.0% |
| 3506633 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.51 | 37.0 | 4.15e-01 | 80.4% | 100.0% |
| 3709456 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.51 | 40.0 | 4.13e-01 | 83.1% | 98.6% |
| 4936768 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.50 | 44.0 | 4.16e-01 | 94.6% | 98.9% |
| 4586449 | 304.48.1.4 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc | 0.50 | 45.0 | 4.14e-01 | 98.0% | 91.3% |
D5
medium
residues 641-742