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RNA-dependent_RNA_polymerase
Euk-VirWuchang_cockroach_Virus_4
RNA-dependent_RNA_polymerase__YP_009342297__Wuchang_cockroach_Virus_4__1923688
Identity
- Accession:
- YP_009342297 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
69.0
mean pLDDT
Cluster
View cluster (2 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 20-34_53-193
D2
medium
residues 194-218_360-404_449-516
Domain cluster:
rep: hypothetical_protein_2__YP_009337432__Changjiang_tombus-like_virus_5__1922819__D23-82_137-181
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nndA01 | 3.10.10.10 | Alpha Beta › Roll › HIV Type 1 Reverse Transcriptase; Chain A, domain 1 › HIV Type 1 Reverse Transcriptase, subunit A, domain 1 | 0.61 | 35.0 | 4.15e-01 | 91.3% | 83.7% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.58 | 23.0 | 3.06e-01 | 79.0% | 64.9% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 23.0 | 3.49e-01 | 81.9% | 96.4% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 22.0 | 2.86e-01 | 77.5% | 64.0% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.53 | 23.0 | 2.81e-01 | 83.3% | 60.2% |
| 4gniA04 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.51 | 23.0 | 2.82e-01 | 92.8% | 62.8% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4875416 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.73 | 68.0 | 4.84e-01 | 100.0% | 63.3% |
| 4804033 | 304.48.1.12 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol | 0.73 | 62.0 | 4.35e-01 | 89.9% | 78.9% |
| 4516798 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.69 | 54.0 | 3.67e-01 | 81.9% | 30.3% |
| 4071235 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.67 | 52.0 | 3.50e-01 | 81.9% | 28.1% |
| 2636124 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.65 | 59.0 | 4.91e-01 | 98.6% | 69.2% |
| 4959042 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.61 | 32.0 | 3.63e-01 | 76.8% | 64.8% |
| 3934979 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.57 | 48.0 | 3.59e-01 | 97.8% | 37.6% |
| 3251732 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.56 | 49.0 | 3.86e-01 | 97.1% | 47.4% |
| 3937811 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.55 | 45.0 | 4.38e-01 | 97.1% | 78.7% |
| 3937440 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 46.0 | 3.69e-01 | 97.1% | 46.4% |
| 3933890 | 101.1.1.76 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Integrase_H2C2 | 0.54 | 25.0 | 2.94e-01 | 92.8% | 60.0% |
| 3937875 | 101.1.1.76 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Integrase_H2C2 | 0.54 | 25.0 | 2.88e-01 | 92.0% | 58.0% |
D3
medium
residues 219-237_405-448_517-655
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337087__Hubei_narna-like_virus_4__1922958__D375-415_481-588
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mw7A03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.70 | 28.0 | 4.54e-01 | 80.2% | 100.0% |
| 1konA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.70 | 27.0 | 4.32e-01 | 81.7% | 94.7% |
| 1s48A04 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.69 | 39.0 | 5.15e-01 | 86.1% | 100.0% |
| 1gx5A03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.69 | 42.0 | 5.34e-01 | 87.1% | 100.0% |
| 1lfpA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.68 | 27.0 | 4.30e-01 | 81.2% | 97.3% |
| 1jqgA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.67 | 29.0 | 4.25e-01 | 77.7% | 89.0% |
| 4ol8A01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.65 | 38.0 | 4.63e-01 | 98.0% | 86.7% |
| 3d68A01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.63 | 28.0 | 4.09e-01 | 79.2% | 92.4% |
| 3kkfA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 30.0 | 4.08e-01 | 78.2% | 94.3% |
| 3mtkA00 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.57 | 38.0 | 4.26e-01 | 84.7% | 84.7% |
| 2pgcA02 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 31.0 | 4.12e-01 | 89.1% | 100.0% |
| 1bwvA01 | 3.30.70.150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain | 0.55 | 34.0 | 4.21e-01 | 86.6% | 97.7% |
| 3pjxA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.54 | 38.0 | 4.07e-01 | 83.2% | 80.7% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4653000 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.75 | 28.0 | 4.78e-01 | 80.7% | 100.0% |
| 4215184 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.73 | 28.0 | 4.68e-01 | 79.7% | 100.0% |
| 4101997 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.73 | 27.0 | 4.63e-01 | 75.2% | 100.0% |
| 4279811 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.73 | 27.0 | 4.35e-01 | 80.7% | 87.5% |
| 4678773 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.72 | 28.0 | 4.56e-01 | 81.2% | 96.0% |
| 4077183 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.71 | 28.0 | 4.50e-01 | 79.7% | 100.0% |
| 4070496 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.71 | 28.0 | 4.55e-01 | 81.7% | 97.3% |
| 4403260 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.70 | 28.0 | 4.48e-01 | 81.2% | 97.3% |
| 5445 | 304.117.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC | 0.70 | 28.0 | 4.54e-01 | 80.2% | 100.0% |
| 4658950 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.70 | 29.0 | 4.49e-01 | 81.7% | 100.0% |
| 4231349 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.69 | 27.0 | 4.34e-01 | 81.2% | 100.0% |
| 4493767 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.68 | 27.0 | 4.31e-01 | 78.2% | 100.0% |
| 4357399 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.68 | 26.0 | 4.32e-01 | 80.7% | 100.0% |
| 4295716 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.67 | 27.0 | 4.23e-01 | 80.2% | 100.0% |
| 4502075 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.66 | 26.0 | 4.12e-01 | 81.2% | 98.6% |
| 4594407 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.65 | 27.0 | 4.10e-01 | 81.7% | 97.3% |
| 3626328 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.64 | 27.0 | 4.18e-01 | 82.2% | 98.8% |
| 3419603 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.58 | 27.0 | 4.02e-01 | 78.7% | 100.0% |
| 3178234 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.57 | 27.0 | 3.85e-01 | 80.7% | 98.9% |
| 3246837 | 304.151.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase | 0.56 | 28.0 | 3.86e-01 | 81.2% | 96.0% |
| 3842059 | 11.1.1.927 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29951 | 0.52 | 33.0 | 3.93e-01 | 87.6% | 100.0% |
| 4088089 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.51 | 45.0 | 3.87e-01 | 94.6% | 69.4% |
D4
medium
residues 238-359
D5
medium
residues 656-749
D6
medium
residues 750-852_895-958
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1aisB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 31.0 | 4.00e-01 | 88.0% | 98.9% |
| 7ml0M01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.52 | 27.0 | 3.65e-01 | 86.2% | 100.0% |
| 1zp2A02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.51 | 32.0 | 3.81e-01 | 91.6% | 94.6% |
| 6ig5A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.51 | 37.0 | 4.02e-01 | 74.9% | 97.1% |
| 2ivxB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.50 | 33.0 | 3.88e-01 | 90.4% | 95.7% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 30.0 | 3.49e-01 | 98.8% | 81.7% |