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RNA-dependent_RNA_polymerase
Euk-VirWuhan_spider_virus_7
RNA-dependent_RNA_polymerase__YP_009344979__Wuhan_spider_virus_7__1923756
Identity
- Accession:
- YP_009344979 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
77.1
mean pLDDT
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-93
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 46.0 | 4.23e-01 | 72.0% | 99.1% |
| 2fgyA01 | 1.20.120.1310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Carboxysome Shell Carbonic Anhydrase, N-terminal helical domain | 0.66 | 47.0 | 4.52e-01 | 100.0% | 65.4% |
| 8thmA01 | 1.20.120.1310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Carboxysome Shell Carbonic Anhydrase, N-terminal helical domain | 0.64 | 46.0 | 4.87e-01 | 100.0% | 87.5% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.59 | 53.0 | 4.48e-01 | 100.0% | 69.5% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.57 | 41.0 | 4.30e-01 | 94.6% | 83.5% |
| 4hhyC01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.55 | 37.0 | 3.34e-01 | 94.6% | 48.1% |
| 3kmiA00 | 1.20.120.940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain | 0.55 | 48.0 | 3.97e-01 | 98.9% | 94.2% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.54 | 47.0 | 4.29e-01 | 97.8% | 84.1% |
| 1zvwA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.54 | 25.0 | 2.97e-01 | 76.3% | 60.6% |
| 1lfuP00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.53 | 36.0 | 3.78e-01 | 86.0% | 78.0% |
| 1rc2A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.53 | 46.0 | 3.46e-01 | 97.8% | 90.5% |
| 1dj8A00 | 1.10.890.10 | Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › HNS-dependent expression A | 0.52 | 35.0 | 3.74e-01 | 80.6% | 83.5% |
| 1zq9A02 | 1.10.8.480 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.52 | 39.0 | 3.84e-01 | 80.6% | 91.8% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5028755 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.72 | 46.0 | 4.61e-01 | 100.0% | 63.2% |
| 3786815 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 42.0 | 4.40e-01 | 96.8% | 74.1% |
| 3840721 | 609.1.1.1 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg | 0.58 | 41.0 | 3.48e-01 | 93.5% | 44.7% |
| 3105724 | 609.1.1.1 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg | 0.57 | 38.0 | 3.45e-01 | 93.5% | 48.5% |
| 3741022 | 101.1.22.0 ↗ | alpha arrays › HTH › HTH › double HTH | 0.57 | 40.0 | 3.70e-01 | 86.0% | 56.7% |
| 3572779 | 3855.1.1.1 ↗ | alpha arrays › Serum amyloid A-1 protein › Serum amyloid A-1 protein › Serum amyloid A-1 protein › SAA | 0.54 | 38.0 | 3.63e-01 | 73.1% | 65.5% |
| 3683128 | 601.39.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 › DUF1666 | 0.54 | 49.0 | 4.00e-01 | 98.9% | 67.9% |
| 3930713 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.53 | 41.0 | 3.78e-01 | 86.0% | 65.4% |
| 4973692 | 182.1.3.0 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX | 0.53 | 39.0 | 3.85e-01 | 86.0% | 73.0% |
| 4034377 | 4982.1.1.2 ↗ | alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain › RsbU_N | 0.52 | 43.0 | 4.45e-01 | 92.5% | 91.1% |
| 5022179 | 632.3.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain | 0.52 | 40.0 | 3.85e-01 | 94.6% | 71.4% |
| 3933696 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 31.0 | 3.55e-01 | 80.6% | 81.4% |
| 3319313 | 2006.1.4.33 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › Tim17 | 0.51 | 39.0 | 3.54e-01 | 80.6% | 68.8% |
| 2589759 | 4064.1.1.2 ↗ | a+b complex topology › Inner layer core protein p3-related › Inner layer core protein p3-related › Inner layer core protein p3-related › Rota_VP2 | 0.50 | 45.0 | 2.63e-01 | 98.9% | 41.4% |
| 3411777 | 101.1.2.352 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_Tnp_Tc5 | 0.50 | 40.0 | 4.07e-01 | 84.9% | 86.7% |
D2
medium
residues 94-215
D3
medium
residues 216-265_348-389_458-482
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337789__Hubei_mosquito_virus_3__1922927__D96-120_142-166_191-245_318-333
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3pfyA01 | 3.30.200.90 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › | 0.52 | 31.0 | 3.75e-01 | 97.4% | 95.8% |
| 4ivkA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.51 | 39.0 | 2.80e-01 | 82.9% | 89.9% |
| 1yz7A02 | 3.30.70.1130 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha | 0.51 | 27.0 | 3.00e-01 | 94.0% | 63.3% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3792091 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.71 | 51.0 | 3.59e-01 | 74.4% | 57.4% |
| 3615272 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.70 | 51.0 | 3.54e-01 | 76.1% | 57.9% |
| 3598902 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.67 | 49.0 | 3.44e-01 | 76.9% | 58.2% |
| 5014287 | 327.11.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) | 0.59 | 30.0 | 3.40e-01 | 84.6% | 62.2% |
| 5022436 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.59 | 31.0 | 3.57e-01 | 100.0% | 69.9% |
| 4994596 | 327.13.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system | 0.53 | 29.0 | 3.26e-01 | 100.0% | 67.0% |
| 4183868 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.50 | 29.0 | 3.42e-01 | 97.4% | 83.5% |
D4
medium
residues 266-347
D5
medium
residues 390-457_483-593
D6
medium
residues 663-738_787-810