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RNA-dependent_RNA_polymerase

Euk-Vir

Lake_Sinai_Virus_SA2

RNA-dependent_RNA_polymerase__YP_009388491__Lake_Sinai_Virus_SA2__1983563

Identity

Accession:
YP_009388491 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

74.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-109
PDB
D2 medium residues 110-250_337-355
PDB
D3 medium residues 251-296_356-393
PDB
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a6qA01 3.40.1620.10 Alpha Beta › 3-Layer(aba) Sandwich › YefM-like fold › YefM-like domain 0.55 28.0 3.72e-01 89.3% 95.3%
1kaeA03 1.20.5.1300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 27.0 3.26e-01 90.5% 69.1%
2pvpA01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 34.0 3.05e-01 96.4% 43.7%
1pvmA00 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.54 38.0 3.06e-01 76.2% 78.1%
6o38A04 2.60.120.1230 Mainly Beta › Sandwich › Jelly Rolls › 0.53 30.0 3.02e-01 92.9% 51.7%
3zieD00 3.30.110.150 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein 0.52 33.0 3.41e-01 100.0% 65.9%
3hryA01 3.40.1620.10 Alpha Beta › 3-Layer(aba) Sandwich › YefM-like fold › YefM-like domain 0.52 26.0 3.29e-01 90.5% 81.6%
2yziB00 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.52 28.0 2.46e-01 92.9% 31.9%
4g09A03 1.20.5.1300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.51 27.0 3.26e-01 98.8% 76.4%
1sq5C00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 37.0 2.59e-01 79.8% 97.3%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5366 304.48.1.15 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 0.82 75.0 4.72e-01 100.0% 39.2%
3260077 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.75 68.0 4.34e-01 100.0% 41.3%
3645993 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 67.0 4.27e-01 100.0% 40.3%
3784946 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.73 65.0 4.16e-01 100.0% 38.3%
3960648 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 61.0 4.15e-01 98.8% 51.8%
2636124 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 57.0 4.19e-01 100.0% 59.4%
4043003 601.7.1.6 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase 0.55 43.0 3.51e-01 88.1% 55.3%
2581340 520.2.1.1 beta sandwiches › gp9 N-terminal domain-like › beta-sandwich domain in metalloprotease stcE › beta-sandwich domain in metalloprotease stcE › StcE_b-sandwich 0.54 30.0 3.02e-01 91.7% 51.7%
5042330 4203.1.1.0 few secondary structure elements › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 redox switch-like 0.52 33.0 3.54e-01 78.6% 75.7%
3480783 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.51 38.0 2.64e-01 83.3% 81.2%
D4 medium residues 297-336_394-479
PDB
D5 medium residues 480-625
PDB