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RNA-dependent_RNA_polymerase

Euk-Vir

Neofusicoccum_luteum_mitovirus_1

RNA-dependent_RNA_polymerase__YP_009388498__Neofusicoccum_luteum_mitovirus_1__1985159

Identity

Accession:
YP_009388498 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

71.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 543-630
PDB
D2 medium residues 1-121
PDB
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 37.0 4.59e-01 73.6% 86.5%
7vwtA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.66 50.0 3.69e-01 80.2% 48.3%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 35.0 4.21e-01 78.5% 93.3%
2k73A00 1.20.1550.10 Mainly Alpha › Up-down Bundle › Bromodomain-like › DsbB-like 0.57 51.0 4.49e-01 100.0% 85.2%
1abvA00 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.57 45.0 4.78e-01 84.3% 97.1%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.57 37.0 3.19e-01 94.2% 40.8%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.57 44.0 4.73e-01 81.8% 100.0%
6wbvA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.57 51.0 3.51e-01 100.0% 65.7%
3dzaA01 1.20.120.1940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain 0.56 35.0 3.59e-01 71.9% 65.0%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.55 42.0 3.74e-01 79.3% 89.9%
3ciaA03 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.55 38.0 3.49e-01 77.7% 55.5%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 44.0 4.03e-01 87.6% 83.2%
1m2vB01 1.20.120.730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain 0.54 44.0 3.93e-01 86.8% 63.3%
1aisB01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.53 36.0 3.89e-01 88.4% 82.8%
4fb2A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 43.0 3.11e-01 91.7% 72.7%
4uz0A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 28.0 3.15e-01 86.0% 69.0%
2xheA03 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.51 45.0 4.56e-01 99.2% 93.4%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.51 35.0 3.74e-01 76.0% 81.1%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.51 39.0 4.02e-01 81.8% 84.0%
2xq0A03 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.51 39.0 3.57e-01 85.1% 61.8%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5014075 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.64 36.0 4.09e-01 74.4% 73.3%
3574876 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.63 42.0 4.10e-01 86.8% 61.5%
4805048 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.62 39.0 4.25e-01 79.3% 75.5%
3970522 5050.1.1.54 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp 0.57 45.0 3.94e-01 84.3% 84.3%
3253573 593.1.1.0 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like 0.57 50.0 3.87e-01 95.9% 95.1%
4386395 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.56 44.0 4.70e-01 82.6% 100.0%
3984201 192.2.1.73 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › MscS_porin 0.55 50.0 3.36e-01 100.0% 38.9%
3254975 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.53 39.0 4.03e-01 79.3% 80.9%
5064398 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.53 36.0 3.90e-01 90.1% 84.0%
3948661 3860.1.1.167 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin 0.52 47.0 3.32e-01 100.0% 42.1%
3936362 192.5.1.21 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › TF_AP-2 0.52 42.0 4.13e-01 86.8% 89.2%
3592529 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 45.0 2.88e-01 98.3% 53.4%
3697052 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 45.0 3.76e-01 99.2% 89.8%
4946261 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 43.0 3.78e-01 95.9% 100.0%
4318405 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 41.0 3.62e-01 87.6% 87.2%
3982121 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 40.0 3.60e-01 86.8% 94.3%
D3 medium residues 122-276_326-359
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 79.3 4.50e-22 64.0% 23.5%
PF05919.17 Mitovir_RNA_pol 28.7 9.70e-07 18.5% 6.6%
D4 medium residues 277-325_360-433
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 140.3 1.40e-40 61.0% 14.9%
PF05919.17 Mitovir_RNA_pol 69.0 6.10e-19 40.6% 10.3%
D5 medium residues 434-541
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 43.1 4.30e-11 97.2% 20.9%