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RNA-dependent_RNA_polymerase
Euk-VirNeofusicoccum_luteum_mitovirus_1
RNA-dependent_RNA_polymerase__YP_009388498__Neofusicoccum_luteum_mitovirus_1__1985159
Identity
- Accession:
- YP_009388498 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
71.9
mean pLDDT
Taxonomy
Orthornavirae›
Lenarviricota›
Amabiliviricetes›
Wolframvirales›
Narnaviridae›
Neofusicoccum_luteum_mitovirus_1
TaxID: 1985159
Cluster
View cluster (26 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 543-630
D2
medium
residues 1-121
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009465715__Erysiphe_necator_mitovirus_1__2052561__D5-113
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 37.0 | 4.59e-01 | 73.6% | 86.5% |
| 7vwtA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.66 | 50.0 | 3.69e-01 | 80.2% | 48.3% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 35.0 | 4.21e-01 | 78.5% | 93.3% |
| 2k73A00 | 1.20.1550.10 | Mainly Alpha › Up-down Bundle › Bromodomain-like › DsbB-like | 0.57 | 51.0 | 4.49e-01 | 100.0% | 85.2% |
| 1abvA00 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.57 | 45.0 | 4.78e-01 | 84.3% | 97.1% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.57 | 37.0 | 3.19e-01 | 94.2% | 40.8% |
| 7p2yd01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.57 | 44.0 | 4.73e-01 | 81.8% | 100.0% |
| 6wbvA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 51.0 | 3.51e-01 | 100.0% | 65.7% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.56 | 35.0 | 3.59e-01 | 71.9% | 65.0% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.55 | 42.0 | 3.74e-01 | 79.3% | 89.9% |
| 3ciaA03 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.55 | 38.0 | 3.49e-01 | 77.7% | 55.5% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 44.0 | 4.03e-01 | 87.6% | 83.2% |
| 1m2vB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.54 | 44.0 | 3.93e-01 | 86.8% | 63.3% |
| 1aisB01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 36.0 | 3.89e-01 | 88.4% | 82.8% |
| 4fb2A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.53 | 43.0 | 3.11e-01 | 91.7% | 72.7% |
| 4uz0A00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.52 | 28.0 | 3.15e-01 | 86.0% | 69.0% |
| 2xheA03 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.51 | 45.0 | 4.56e-01 | 99.2% | 93.4% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.51 | 35.0 | 3.74e-01 | 76.0% | 81.1% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.51 | 39.0 | 4.02e-01 | 81.8% | 84.0% |
| 2xq0A03 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.51 | 39.0 | 3.57e-01 | 85.1% | 61.8% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5014075 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.64 | 36.0 | 4.09e-01 | 74.4% | 73.3% |
| 3574876 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.63 | 42.0 | 4.10e-01 | 86.8% | 61.5% |
| 4805048 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.62 | 39.0 | 4.25e-01 | 79.3% | 75.5% |
| 3970522 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.57 | 45.0 | 3.94e-01 | 84.3% | 84.3% |
| 3253573 | 593.1.1.0 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like | 0.57 | 50.0 | 3.87e-01 | 95.9% | 95.1% |
| 4386395 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.56 | 44.0 | 4.70e-01 | 82.6% | 100.0% |
| 3984201 | 192.2.1.73 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › MscS_porin | 0.55 | 50.0 | 3.36e-01 | 100.0% | 38.9% |
| 3254975 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.53 | 39.0 | 4.03e-01 | 79.3% | 80.9% |
| 5064398 | 101.1.10.3 ↗ | alpha arrays › HTH › HTH › Cyclin-like › TFIIB | 0.53 | 36.0 | 3.90e-01 | 90.1% | 84.0% |
| 3948661 | 3860.1.1.167 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin | 0.52 | 47.0 | 3.32e-01 | 100.0% | 42.1% |
| 3936362 | 192.5.1.21 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › TF_AP-2 | 0.52 | 42.0 | 4.13e-01 | 86.8% | 89.2% |
| 3592529 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 45.0 | 2.88e-01 | 98.3% | 53.4% |
| 3697052 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 45.0 | 3.76e-01 | 99.2% | 89.8% |
| 4946261 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 43.0 | 3.78e-01 | 95.9% | 100.0% |
| 4318405 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 41.0 | 3.62e-01 | 87.6% | 87.2% |
| 3982121 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 40.0 | 3.60e-01 | 86.8% | 94.3% |
D3
medium
residues 122-276_326-359
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009259482__Cronartium_ribicola_mitovirus_3__1816486__D153-243_260-277
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 79.3 | 4.50e-22 | 64.0% | 23.5% |
| PF05919.17 | Mitovir_RNA_pol | 28.7 | 9.70e-07 | 18.5% | 6.6% |
D4
medium
residues 277-325_360-433
Domain cluster:
rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 140.3 | 1.40e-40 | 61.0% | 14.9% |
| PF05919.17 | Mitovir_RNA_pol | 69.0 | 6.10e-19 | 40.6% | 10.3% |
D5
medium
residues 434-541
Domain cluster:
rep: RNA_dependent_RNA_polymerase__YP_009182163__Botrytis_cinerea_mitovirus_4__1629667__D438-532
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 43.1 | 4.30e-11 | 97.2% | 20.9% |