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RNA-dependent_RNA_polymerase
Euk-VirErysiphe_necator_mitovirus_2
RNA-dependent_RNA_polymerase__YP_009465716__Erysiphe_necator_mitovirus_2__2052562
Identity
- Accession:
- YP_009465716 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
67.0
mean pLDDT
Taxonomy
Orthornavirae›
Lenarviricota›
Howeltoviricetes›
Cryppavirales›
Mitoviridae›
Mitovirus›
Erysiphe_necator_mitovirus_2
TaxID: 2052562
Cluster
View cluster (26 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 14-106_433-461
Domain cluster:
rep: RNA_dependent_RNA_polymerase__YP_005352912__Clitocybe_odora_virus__1162083__D59-187_563-580
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.64 | 44.0 | 4.51e-01 | 70.5% | 99.2% |
| 2jokA01 | 1.10.4120.10 | Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain | 0.62 | 47.0 | 4.14e-01 | 79.5% | 78.3% |
| 7vwtA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 54.0 | 4.00e-01 | 98.4% | 40.3% |
| 5t3wA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 35.0 | 3.41e-01 | 97.5% | 50.4% |
| 6ks6G01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.59 | 48.0 | 3.74e-01 | 86.1% | 75.8% |
| 1bucA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 37.0 | 3.76e-01 | 95.9% | 65.9% |
| 1abvA00 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.54 | 43.0 | 4.58e-01 | 84.4% | 98.1% |
| 2cfqA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 37.0 | 3.11e-01 | 83.6% | 41.0% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 29.0 | 3.33e-01 | 91.0% | 71.4% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 34.0 | 3.76e-01 | 70.5% | 78.2% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.53 | 41.0 | 3.75e-01 | 82.0% | 94.6% |
| 2b1eA03 | 1.10.357.60 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.53 | 38.0 | 3.46e-01 | 75.4% | 74.4% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 39.0 | 3.32e-01 | 81.1% | 49.0% |
| 2xq0A03 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.51 | 47.0 | 4.32e-01 | 100.0% | 89.8% |
| 3errA01 | 1.20.920.60 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.51 | 32.0 | 2.74e-01 | 100.0% | 36.5% |
| 2w1zA01 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.51 | 43.0 | 3.58e-01 | 92.6% | 73.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 34.0 | 3.40e-01 | 81.1% | 66.4% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4027730 | 320.4.1.3 ↗ | a+b two layers › R3H domain-like › PUB domain › PUB domain › PUB | 0.72 | 53.0 | 5.44e-01 | 75.4% | 96.5% |
| 3613847 | 593.1.1.1 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 | 0.61 | 50.0 | 3.85e-01 | 86.1% | 85.3% |
| 3906775 | 3921.1.1.0 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D | 0.61 | 49.0 | 4.66e-01 | 86.9% | 89.0% |
| 3594965 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.57 | 31.0 | 2.96e-01 | 98.4% | 43.6% |
| 5018995 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.55 | 44.0 | 3.64e-01 | 85.2% | 82.7% |
| 4034151 | 604.39.1.9 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 | 0.55 | 50.0 | 4.12e-01 | 100.0% | 60.9% |
| 3720518 | 320.4.1.1 ↗ | a+b two layers › R3H domain-like › PUB domain › PUB domain › TIMELESS_C | 0.54 | 44.0 | 4.11e-01 | 87.7% | 93.5% |
| 3452310 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.54 | 48.0 | 4.23e-01 | 97.5% | 71.7% |
| 5084032 | 5050.1.1.53 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC | 0.53 | 45.0 | 3.80e-01 | 93.4% | 85.4% |
| 3548125 | 3930.1.1.2 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RIG-I_C | 0.53 | 39.0 | 3.84e-01 | 76.2% | 76.9% |
| 3935622 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 37.0 | 3.10e-01 | 83.6% | 43.5% |
| 5066876 | 1079.1.1.12 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › GDT1 | 0.53 | 42.0 | 3.78e-01 | 86.9% | 80.0% |
| 3232602 | 197.1.1.3 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › ACBP | 0.52 | 31.0 | 3.49e-01 | 81.1% | 78.9% |
| 4001562 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.51 | 46.0 | 3.10e-01 | 100.0% | 80.5% |
| 3655677 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.50 | 36.0 | 3.15e-01 | 75.4% | 68.4% |
| 3426236 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.50 | 36.0 | 3.31e-01 | 74.6% | 74.4% |
| 5037363 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 37.0 | 3.21e-01 | 81.1% | 50.3% |
D2
medium
residues 119-146_263-432
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009508056__Heterobasidion_partitivirus_15__1469908__D97-135_228-464
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 287.2 | 4.30e-85 | 88.4% | 34.6% |
D3
medium
residues 147-262
Domain cluster:
rep: putative_RNA-dependent_RNA_polymerase__YP_009249807__Rhizoctonia_oryzae-sativae_mitovirus_1__1837089__D175-218_233-338
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 77.3 | 1.80e-21 | 100.0% | 24.1% |