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RNA-dependent_RNA_polymerase
Euk-VirChondrostereum_purpureum_cryptic_virus_1
RNA-dependent_RNA_polymerase__YP_009508236__Chondrostereum_purpureum_cryptic_virus_1__529380
Identity
- Accession:
- YP_009508236 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
88.6
mean pLDDT
Cluster
View cluster (450 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 41-77_468-559
D2
medium
residues 28-40_113-130_232-253_297-366
D3
medium
residues 78-112_415-440
Domain cluster:
representative
D4
medium
residues 131-231
Domain cluster:
representative
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3267570 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.62 | 43.0 | 2.98e-01 | 100.0% | 20.9% |
| 3250871 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.60 | 42.0 | 3.75e-01 | 100.0% | 50.0% |
| 3751719 | 295.1.1.3 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA | 0.51 | 31.0 | 3.27e-01 | 100.0% | 66.7% |
| 3267419 | 601.51.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin › DUF4460 | 0.51 | 35.0 | 3.00e-01 | 71.3% | 93.3% |
D5
medium
residues 254-296_367-414_441-467
Domain cluster:
rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h5xA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.80 | 66.0 | 6.69e-01 | 86.4% | 100.0% |
| 6qwtA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.79 | 74.0 | 6.92e-01 | 100.0% | 97.9% |
| 5jxsA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.78 | 74.0 | 6.88e-01 | 100.0% | 97.2% |
| 1khvA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.78 | 68.0 | 6.55e-01 | 91.5% | 100.0% |
| 1gx5A03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.76 | 65.0 | 6.48e-01 | 91.5% | 100.0% |
| 1ra6A02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.75 | 58.0 | 6.13e-01 | 79.7% | 100.0% |
| 2ckwA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.73 | 60.0 | 6.11e-01 | 86.4% | 100.0% |
| 1hi8A03 | 3.30.70.1600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 65.0 | 5.60e-01 | 100.0% | 88.1% |
| 7uinD01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.66 | 59.0 | 5.22e-01 | 97.5% | 92.8% |
| 4hkqA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.60 | 54.0 | 5.11e-01 | 100.0% | 83.3% |
| 1vbkA01 | 3.30.70.1510 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like | 0.60 | 41.0 | 4.77e-01 | 74.6% | 100.0% |
| 6pwjA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.59 | 49.0 | 4.40e-01 | 89.8% | 78.8% |
| 4zmuA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.57 | 49.0 | 4.46e-01 | 92.4% | 88.4% |
| 7e6gA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.57 | 46.0 | 4.29e-01 | 87.3% | 89.3% |
| 6u26A01 | 3.30.70.80 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 | 0.55 | 35.0 | 3.93e-01 | 73.7% | 85.2% |
| 1ufwA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.54 | 37.0 | 4.09e-01 | 73.7% | 87.4% |
| 1ybtB00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.53 | 39.0 | 3.50e-01 | 78.0% | 89.5% |
| 3smzA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.52 | 41.0 | 4.25e-01 | 98.3% | 90.2% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3185440 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.59 | 45.0 | 3.57e-01 | 79.7% | 95.2% |
| 3267315 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.58 | 42.0 | 3.78e-01 | 76.3% | 73.3% |
| 4214422 | 304.48.1.14 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF | 0.56 | 47.0 | 4.40e-01 | 93.2% | 84.7% |
| 3351675 | 304.7.1.2 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 | 0.56 | 41.0 | 4.48e-01 | 76.3% | 98.9% |
| 4163139 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.54 | 39.0 | 3.78e-01 | 72.9% | 81.5% |
| 4319667 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.54 | 40.0 | 3.57e-01 | 77.1% | 88.2% |
| None | — | 0.54 | 40.0 | 3.64e-01 | 76.3% | 79.4% | |
| 3708806 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 48.0 | 3.90e-01 | 98.3% | 73.8% |
| 5081184 | 321.1.1.1 ↗ | a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › Gln-synt_C | 0.53 | 39.0 | 2.83e-01 | 78.0% | 81.9% |
| 3264109 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.53 | 41.0 | 4.23e-01 | 83.1% | 100.0% |
| 3947466 | 304.48.1.48 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 | 0.52 | 44.0 | 3.93e-01 | 93.2% | 87.6% |
| 2491374 | 304.51.1.16 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas6_csf5 | 0.52 | 39.0 | 3.94e-01 | 79.7% | 95.8% |