RNA-dependent_RNA_polymerase

Euk-Vir

Aspergillus_fumigatus_polymycovirus_1

RNA-dependent_RNA_polymerase__YP_009551547__Aspergillus_fumigatus_polymycovirus_1__2250469

Identity

85.1 mean pLDDT

View cluster (51 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 589-760

PDB

Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_009352879__Beauveria_bassiana_polymycovirus_1__1740646__D597-774

D2 medium residues 1-92

PDB

D3 medium residues 124-157_223-255_415-527

PDB

Domain cluster: rep: NIb__YP_006908987__Rose_yellow_mosaic_virus__1048434__D1-17_73-106_202-219_246-320

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00680.26 best	RdRP_1	33.4	3.00e-08	75.6%	20.9%

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2f5gA00	3.30.70.1290	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like	0.56	24.0	2.85e-01	80.0%	54.6%
1u5tB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	17.0	2.51e-01	70.6%	54.1%
3ezjA02	3.30.1370.120	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 ›	0.51	19.0	3.10e-01	71.7%	89.7%
4qmfB01	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.51	21.0	3.08e-01	70.6%	84.1%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4397598	327.19.1.1 ↗	a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C	0.53	21.0	2.89e-01	80.6%	70.0%
3958860	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.53	27.0	3.50e-01	87.2%	84.3%
3304324	101.1.2.106 ↗	alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37	0.51	28.0	3.23e-01	75.6%	69.6%

D4 medium residues 158-222_324-351

PDB

Domain cluster: representative

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2q0yA01	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.57	31.0	2.73e-01	73.1%	33.3%
2y4tA02	1.10.287.110	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain	0.54	30.0	3.71e-01	91.4%	94.2%
3nkuA00	1.10.357.170	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.52	43.0	3.54e-01	92.5%	88.6%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4964806	220.1.1.76 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2	0.65	47.0	3.93e-01	100.0%	43.8%
4937035	220.1.1.76 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2	0.56	41.0	3.63e-01	100.0%	50.3%
3708807	207.1.1.0 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats	0.56	34.0	2.92e-01	77.4%	36.1%
2647290	225.1.1.6 ↗	a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_2	0.56	33.0	3.49e-01	72.0%	66.3%
3965375	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.54	37.0	3.23e-01	71.0%	80.7%
4028641	5.1.4.1 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40	0.52	42.0	2.53e-01	88.2%	46.9%
3378684	213.1.1.72 ↗	a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1, Acetyltransf_10	0.51	35.0	2.80e-01	72.0%	43.1%
3956258	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.50	40.0	3.42e-01	87.1%	91.6%

D5 medium residues 256-323_352-376

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009342446__Botryosphaeria_dothidea_virus_1__1516075__D245-325

D6 medium residues 528-588

PDB

Domain cluster: representative

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2yvkA01	1.20.120.420	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1	0.51	41.0	3.25e-01	95.1%	81.1%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5078551	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.54	37.0	3.72e-01	93.4%	73.3%