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RNA-dependent_RNA_polymerase

Euk-Vir

Medicago_sativa_alphapartitivirus_1

RNA-dependent_RNA_polymerase__YP_009551597__Medicago_sativa_alphapartitivirus_1__2043550

Identity

Accession:
YP_009551597 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

81.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 105-189
PDB
D2 medium residues 1-22_199-234_351-363
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ib5A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.54 38.0 2.58e-01 77.5% 40.6%
3jzmA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 37.0 2.63e-01 77.5% 78.6%
2g9iA01 3.30.1330.100 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › CofE-like 0.51 44.0 3.63e-01 100.0% 94.2%
4tl8F00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 36.0 2.66e-01 76.1% 87.8%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 36.0 2.78e-01 77.5% 92.9%
1ixmB02 3.30.565.30 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Sporulation initiation phosphotransferase B (SpoOB), C-terminal domain 0.50 40.0 3.49e-01 88.7% 68.8%
5dvyA02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.50 39.0 2.61e-01 87.3% 59.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5033908 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.66 47.0 3.40e-01 76.1% 57.1%
5029815 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.64 45.0 3.27e-01 76.1% 59.1%
3295391 2007.2.3.9 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › PTPlike_phytase 0.56 38.0 2.52e-01 71.8% 46.5%
4981955 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.56 44.0 3.65e-01 87.3% 86.9%
4392521 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.56 38.0 2.56e-01 71.8% 34.7%
5041727 2492.1.1.0 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like 0.55 44.0 3.53e-01 93.0% 92.5%
4247735 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.54 37.0 2.10e-01 70.4% 9.6%
4979109 2006.1.4.56 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF5615 0.54 39.0 3.34e-01 77.5% 68.1%
3735731 2008.2.1.2 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › Sen15 0.53 38.0 3.17e-01 77.5% 64.7%
4955135 2008.1.1.159 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Csa1 0.53 38.0 2.54e-01 76.1% 34.2%
5008124 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.53 37.0 2.72e-01 76.1% 90.0%
3598626 2008.2.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like 0.51 36.0 3.41e-01 74.6% 64.4%
5077272 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.51 36.0 2.59e-01 77.5% 80.7%
3242647 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.51 39.0 2.90e-01 84.5% 49.5%
3502215 7026.1.1.0 beta meanders › N-terminal region of lipid transporter Vps13 › N-terminal region of lipid transporter Vps13 › N-terminal region of lipid transporter Vps13 0.51 35.0 2.37e-01 71.8% 44.6%
3741335 109.4.1.338 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 0.51 35.0 2.36e-01 71.8% 43.7%
3937781 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.51 38.0 2.85e-01 84.5% 50.2%
5012532 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.50 36.0 2.62e-01 77.5% 90.0%
D3 medium residues 23-62_456-573
PDB
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ckwA04 1.20.960.20 Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › 0.59 39.0 4.59e-01 71.5% 97.2%
3tahA02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 29.0 3.67e-01 70.3% 83.0%
2xheA04 1.25.40.60 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 30.0 3.42e-01 72.2% 71.2%
2afaA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.53 40.0 2.93e-01 77.2% 48.8%
3gt5A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.53 41.0 3.09e-01 81.6% 78.0%
3n3uA00 1.10.3290.10 Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain 0.51 39.0 3.21e-01 93.7% 43.0%
D4 medium residues 63-100_254-295_364-455
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 30.6 2.10e-07 55.2% 19.8%