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RNA-dependent_RNA_polymerase
Euk-VirLeptosphaeria_biglobosa_mitovirus_1
RNA-dependent_RNA_polymerase__YP_009553599__Leptosphaeria_biglobosa_mitovirus_1__2163916
Identity
- Accession:
- YP_009553599 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
70.5
mean pLDDT
Taxonomy
Orthornavirae›
Lenarviricota›
Howeltoviricetes›
Cryppavirales›
Mitoviridae›
Unuamitovirus›
Leptosphaeria_biglobosa_mitovirus_1
TaxID: 2163916
Cluster
View cluster (26 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-129
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009465715__Erysiphe_necator_mitovirus_1__2052561__D5-113
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6ks6a01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.70 | 60.0 | 4.65e-01 | 93.0% | 96.4% |
| 6ks6Z01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.68 | 58.0 | 4.57e-01 | 93.0% | 94.4% |
| 6ks6q01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.67 | 57.0 | 4.46e-01 | 91.5% | 91.6% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.67 | 57.0 | 4.65e-01 | 93.0% | 98.4% |
| 7vwtA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.66 | 46.0 | 3.47e-01 | 72.1% | 48.6% |
| 1abvA00 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.59 | 42.0 | 4.56e-01 | 73.6% | 100.0% |
| 2k73A00 | 1.20.1550.10 | Mainly Alpha › Up-down Bundle › Bromodomain-like › DsbB-like | 0.58 | 51.0 | 4.56e-01 | 96.1% | 85.8% |
| 7p2yd01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.56 | 41.0 | 4.55e-01 | 76.7% | 100.0% |
| 3kdqA00 | 6.10.320.10 | Special › Helix non-globular › Ferritin › | 0.54 | 35.0 | 3.31e-01 | 94.6% | 55.9% |
| 1tu9A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 37.0 | 3.78e-01 | 93.0% | 72.5% |
| 2wauA01 | 1.20.1310.20 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain | 0.51 | 38.0 | 3.63e-01 | 77.5% | 67.1% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 40.0 | 3.22e-01 | 82.9% | 86.3% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.50 | 35.0 | 3.70e-01 | 72.1% | 84.0% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3420093 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.66 | 52.0 | 4.08e-01 | 99.2% | 39.6% |
| 2168246 | 1176.1.1.1 ↗ | alpha arrays › Nitrogenase vanadium-iron protein delta chain › Nitrogenase vanadium-iron protein delta chain › Nitrogenase vanadium-iron protein delta chain › AnfG_VnfG | 0.62 | 48.0 | 5.08e-01 | 82.2% | 98.2% |
| 3459032 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.62 | 51.0 | 3.91e-01 | 96.1% | 38.3% |
| 3652633 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.60 | 50.0 | 5.04e-01 | 96.9% | 89.2% |
| 4120183 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.59 | 48.0 | 3.67e-01 | 96.1% | 37.6% |
| 3481054 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.59 | 52.0 | 4.26e-01 | 96.9% | 84.3% |
| 4472717 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.58 | 46.0 | 4.92e-01 | 89.9% | 96.4% |
| 3697466 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 49.0 | 4.13e-01 | 100.0% | 93.5% |
| 1487362 | 3930.2.1.1 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in endoribonuclease Dicer › Helical bundle in endoribonuclease Dicer › Dicer_PBD | 0.53 | 44.0 | 4.57e-01 | 96.1% | 97.5% |
| 4517631 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.53 | 45.0 | 2.97e-01 | 92.2% | 24.3% |
| 3196010 | 3930.1.1.15 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › DEAD, Helicase_C | 0.52 | 44.0 | 2.98e-01 | 91.5% | 27.6% |
| 4282274 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.51 | 39.0 | 3.18e-01 | 79.8% | 77.1% |
| 4426627 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 39.0 | 3.34e-01 | 81.4% | 76.7% |
D2
medium
residues 159-276_324-351
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009259482__Cronartium_ribicola_mitovirus_3__1816486__D153-243_260-277
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 107.2 | 1.60e-30 | 80.1% | 24.8% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1neiA00 | 3.30.160.220 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG | 0.57 | 21.0 | 3.15e-01 | 84.2% | 78.3% |
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.55 | 51.0 | 3.47e-01 | 100.0% | 49.0% |
| 1xjkA00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.52 | 47.0 | 3.12e-01 | 100.0% | 76.3% |
| 2zw3A00 | 1.20.1440.80 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain | 0.51 | 37.0 | 3.34e-01 | 74.0% | 93.0% |
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 47.0 | 4.44e-01 | 100.0% | 83.0% |
| 4djbA00 | 3.30.70.2870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 | 0.50 | 32.0 | 3.53e-01 | 87.7% | 78.8% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3589612 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 51.0 | 3.90e-01 | 100.0% | 60.0% |
| 5018583 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.55 | 51.0 | 3.91e-01 | 100.0% | 59.0% |
| 3945039 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.54 | 50.0 | 3.82e-01 | 100.0% | 59.4% |
| 3209439 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.53 | 49.0 | 3.78e-01 | 100.0% | 61.9% |
| 4564199 | 7512.1.1.3 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 | 0.52 | 37.0 | 3.20e-01 | 74.0% | 90.6% |
| 4152428 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.52 | 47.0 | 3.50e-01 | 98.6% | 56.1% |
| 4002132 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.50 | 38.0 | 3.01e-01 | 80.1% | 56.3% |
| 4019374 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.50 | 45.0 | 3.32e-01 | 100.0% | 62.0% |
D3
medium
residues 277-323_352-442
Domain cluster:
rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05919.17 best | Mitovir_RNA_pol | 187.2 | 8.50e-55 | 66.7% | 18.3% |
| PF05919.17 | Mitovir_RNA_pol | 68.5 | 8.70e-19 | 34.8% | 10.1% |
D4
medium
residues 693-756