RNA-dependent_RNA_polymerase

Euk-Vir

Murine_hepatitis_virus

RNA-dependent_RNA_polymerase__YP_009915683__Murine_hepatitis_virus__11138

Identity

88.8 mean pLDDT

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Betacoronavirus› Murine_hepatitis_virus

TaxID: 11138

View cluster (23 members)

Download PDB Download Scores JSON

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 17-122

PDB

Domain cluster: rep: nsp12__YP_008439222__Bat_coronavirus_CDPHE15_USA_2006__1384461__D18-119

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06478.20 best	CoV_RPol_N	123.9	1.10e-35	100.0%	29.4%

D2 medium residues 123-261

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase__NP_740629__Infectious_bronchitis_virus__11120__D128-266

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06478.20 best	CoV_RPol_N	226.0	9.80e-67	100.0%	38.9%

D3 medium residues 262-356

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06478.20 best	CoV_RPol_N	183.2	9.90e-54	100.0%	26.9%

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5ab0C04	1.25.50.20	Mainly Alpha › Alpha Horseshoe › Zincin-like fold ›	0.55	38.0	2.63e-01	71.6%	21.2%
6j09A04	3.10.20.310	Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac	0.53	29.0	3.20e-01	83.2%	64.9%
3qktD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	40.0	2.83e-01	84.2%	99.7%
1om2A00	1.20.960.10	Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › Mitochondrial outer membrane translocase complex, subunit Tom20 domain	0.50	31.0	3.19e-01	90.5%	62.1%
3bt7A02	2.40.50.1070	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) ›	0.50	41.0	3.68e-01	93.7%	75.2%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2994348	304.48.1.9 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1,CoV_RPol_N	0.98	95.0	5.28e-01	100.0%	10.2%
3242263	391.1.1.0 ↗	few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module	0.63	26.0	3.21e-01	91.6%	58.3%
3510110	391.1.2.9 ↗	few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › Fn1_2	0.54	26.0	3.02e-01	92.6%	61.4%
3504449	391.1.1.7 ↗	few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › Fn1_2	0.54	26.0	3.02e-01	92.6%	61.4%
4302656	387.1.5.0 ↗	few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like	0.52	23.0	3.24e-01	82.1%	86.7%
3959568	3702.1.1.0 ↗	beta complex topology › Penicillin binding protein dimerisation domain › Penicillin binding protein dimerisation domain › Penicillin binding protein dimerisation domain	0.50	37.0	2.69e-01	77.9%	34.1%

D4 medium residues 357-408_432-456_493-557

PDB

Domain cluster: rep: nsp12__YP_009944349__Pipistrellus_bat_coronavirus_HKU5__694008__D359-459_503-534_548-594

D5 medium residues 457-492_558-701

PDB

Domain cluster: rep: NSP12__YP_009825029__Duck_coronavirus__300188__D487-521_603-645_704-728_761-790

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00680.26 best	RdRP_1	52.1	6.30e-14	81.1%	28.4%

D6 medium residues 841-928

PDB

Domain cluster: rep: NSP12__YP_009825029__Duck_coronavirus__300188__D836-945