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RNA-dependent_RNA_polymerase

Euk-Vir

Penicillium_brevicompactum_tetramycovirus_1

RNA-dependent_RNA_polymerase__YP_010086053__Penicillium_brevicompactum_tetramycovirus_1__2485923

Identity

Accession:
YP_010086053 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

83.7 mean pLDDT

Cluster

View cluster (51 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-77
PDB
D2 medium residues 237-249_313-383_426-438_473-493
PDB
Domain cluster: representative
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2757968 304.48.1.12 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol 0.60 41.0 3.34e-01 71.2% 88.9%
D3 medium residues 250-312_439-472
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h37A03 1.20.58.1960 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 36.0 3.29e-01 95.9% 52.3%
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.51 35.0 3.66e-01 75.3% 77.0%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3995593 142.1.1.28 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › RIIa 0.53 33.0 3.66e-01 90.7% 80.0%
D4 medium residues 384-425_494-603
PDB
Domain cluster: rep: ORF1a__YP_010086046__Magnaporthe_oryzae_polymycovirus_1__2509266__D207-227_376-425_521-587
D5 medium residues 604-658
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k6tB00 1.20.5.4010 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.82 56.0 5.91e-01 70.9% 87.8%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 65.0 5.65e-01 92.7% 96.5%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.77 53.0 5.11e-01 70.9% 68.9%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.77 60.0 4.66e-01 83.6% 100.0%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 54.0 4.74e-01 72.7% 64.1%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.76 54.0 5.14e-01 74.5% 87.5%
7nc3F01 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.76 54.0 4.21e-01 74.5% 57.0%
5tqbB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.71 59.0 3.61e-01 90.9% 16.3%
2vm6A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.71 61.0 4.57e-01 100.0% 57.6%
1vw4L01 3.90.1030.10 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 0.68 49.0 3.63e-01 76.4% 61.5%
3a7rA02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.68 55.0 4.75e-01 92.7% 58.4%
2guzA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.64 55.0 5.08e-01 96.4% 97.2%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 54.0 4.34e-01 100.0% 89.8%
2e9xD01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 49.0 3.74e-01 87.3% 73.0%
6b8hO01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.60 49.0 4.08e-01 90.9% 54.5%
2ygwA01 1.20.140.90 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain 0.59 48.0 3.64e-01 96.4% 72.5%
4l8eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 45.0 3.87e-01 96.4% 79.1%
3p42A02 6.10.250.2280 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.57 40.0 3.75e-01 74.5% 57.1%
1qd1B02 3.30.70.670 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Formiminotransferase, C-terminal subdomain 0.56 47.0 3.60e-01 100.0% 64.1%
4gtnA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.53 44.0 4.06e-01 96.4% 75.7%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3597917 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.81 59.0 4.58e-01 78.2% 40.0%
1826901 604.35.1.1 ↗ alpha bundles › Spectrin repeat-like › Organelle protein MG491 central domain › Organelle protein MG491 central domain › MG491_central 0.78 67.0 4.90e-01 94.5% 77.8%
3926306 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 62.0 4.44e-01 90.9% 32.5%
3471730 192.17.1.0 ↗ alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.75 53.0 5.39e-01 74.5% 87.3%
3610216 650.1.1.1 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.75 57.0 4.79e-01 83.6% 62.1%
3280862 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 66.0 4.78e-01 98.2% 38.7%
3622876 3651.1.1.0 ↗ alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain 0.73 64.0 4.81e-01 100.0% 75.6%
3427143 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.70 55.0 3.85e-01 92.7% 26.5%
3247663 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.68 55.0 3.93e-01 96.4% 81.1%
3660515 601.33.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.67 55.0 5.18e-01 96.4% 95.7%
3601371 109.26.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains 0.67 58.0 3.28e-01 100.0% 11.2%
3641457 192.7.1.0 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.67 54.0 4.27e-01 96.4% 50.0%
3678733 633.16.1.0 ↗ alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like 0.67 55.0 5.17e-01 98.2% 97.1%
4374802 639.2.1.2 ↗ alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › DUF2767 0.65 53.0 5.08e-01 92.7% 89.2%
4216527 563.1.1.1 ↗ alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.64 51.0 4.13e-01 90.9% 49.1%
4232558 218.1.1.8 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.63 48.0 4.08e-01 87.3% 48.0%
5032985 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.63 51.0 3.42e-01 96.4% 35.4%
3673090 529.1.1.0 ↗ few secondary structure elements › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) 0.62 46.0 4.25e-01 85.5% 60.8%
4061283 4030.1.1.0 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.62 47.0 4.83e-01 87.3% 92.0%
3457692 3419.1.1.0 ↗ alpha bundles › Antitoxin VbhA › Antitoxin VbhA › Antitoxin VbhA 0.61 50.0 5.27e-01 98.2% 100.0%
4275894 213.1.1.25 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_3 0.60 46.0 3.28e-01 87.3% 43.9%
3914567 109.4.1.1715 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_TANGO6 0.59 48.0 3.05e-01 100.0% 20.0%
3651218 184.1.1.1 ↗ alpha arrays › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Glycos_trans_3N 0.58 47.0 4.41e-01 90.9% 71.4%
3427512 101.1.17.0 ↗ alpha arrays › HTH › HTH › FF domain 0.58 44.0 4.24e-01 89.1% 76.9%
4407982 101.1.2.22 ↗ alpha arrays › HTH › HTH › winged helix domain › PCI 0.57 45.0 4.11e-01 94.5% 82.5%
3553786 101.1.1.244 ↗ alpha arrays › HTH › HTH › Three-helical HTH › HTH_TIMELESS 0.53 41.0 3.83e-01 90.9% 73.3%
4252854 198.1.1.0 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.53 39.0 3.72e-01 89.1% 78.7%
3201189 10.12.1.21 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › ERG2_Sigma1R 0.53 40.0 2.83e-01 90.9% 66.5%