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RNA-dependent_RNA_polymerase
Euk-VirBetachrysovirus_aspergilli
RNA-dependent_RNA_polymerase__YP_010088028__Betachrysovirus_aspergilli__2164061
Identity
- Accession:
- YP_010088028 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
80.6
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Chrymotiviricetes›
Ghabrivirales›
Chrysoviridae›
Betachrysovirus›
Betachrysovirus_aspergilli
TaxID: 2164061
Cluster
View cluster (12 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 31-59_118-211
Domain cluster:
rep: VP2__YP_009665170__Eriocheir_sinensis_reovirus__273810__D721-872
D2
medium
residues 60-117
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2aw6A02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.80 | 58.0 | 3.81e-01 | 75.9% | 49.8% |
| 1o9gA02 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 55.0 | 6.15e-01 | 86.2% | 97.7% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.78 | 53.0 | 5.65e-01 | 70.7% | 85.4% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.74 | 64.0 | 5.07e-01 | 94.8% | 94.7% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.73 | 53.0 | 5.05e-01 | 75.9% | 68.7% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.73 | 51.0 | 4.82e-01 | 74.1% | 62.0% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 50.0 | 4.66e-01 | 74.1% | 57.3% |
| 4xaxB02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.68 | 56.0 | 4.71e-01 | 91.4% | 78.8% |
| 1cpyA02 | 1.10.287.410 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 55.0 | 5.16e-01 | 93.1% | 97.2% |
| 5u1xA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.66 | 46.0 | 5.01e-01 | 93.1% | 93.5% |
| 2jqtA00 | 1.20.1280.40 | Mainly Alpha › Up-down Bundle › Monooxygenase › HHA | 0.65 | 46.0 | 4.67e-01 | 74.1% | 86.0% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 46.0 | 4.44e-01 | 75.9% | 72.1% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 53.0 | 4.94e-01 | 94.8% | 78.4% |
| 2oo2A00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.60 | 51.0 | 4.76e-01 | 98.3% | 75.0% |
| 1iq0A03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.60 | 53.0 | 4.24e-01 | 100.0% | 72.4% |
| 2zueA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.58 | 52.0 | 4.09e-01 | 100.0% | 73.1% |
| 1t07A00 | 1.10.3880.10 | Mainly Alpha › Orthogonal Bundle › YggX-like › Fe(II) trafficking protein YggX | 0.58 | 45.0 | 4.03e-01 | 91.4% | 60.5% |
| 4wr4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 42.0 | 3.60e-01 | 82.8% | 82.9% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 48.0 | 3.06e-01 | 100.0% | 38.7% |
| 4azcA02 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.54 | 42.0 | 4.19e-01 | 86.2% | 84.7% |
| 1gs0A01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.54 | 47.0 | 3.58e-01 | 94.8% | 58.9% |
| 2k8oA00 | 1.20.5.2120 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.53 | 39.0 | 3.90e-01 | 93.1% | 78.3% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3708959 | 601.24.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FRB_dom | 0.80 | 67.0 | 5.68e-01 | 93.1% | 94.7% |
| 4956241 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.76 | 62.0 | 5.62e-01 | 86.2% | 80.0% |
| 4329615 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.73 | 52.0 | 4.93e-01 | 75.9% | 67.1% |
| 5078048 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.73 | 51.0 | 4.73e-01 | 74.1% | 61.3% |
| 4960850 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.72 | 50.0 | 5.01e-01 | 72.4% | 76.7% |
| 4089954 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.72 | 47.0 | 5.22e-01 | 86.2% | 86.7% |
| 3718917 | 6132.1.1.0 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain | 0.71 | 57.0 | 5.23e-01 | 93.1% | 68.0% |
| 4942064 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.70 | 59.0 | 5.74e-01 | 93.1% | 83.1% |
| 3977423 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.70 | 46.0 | 4.79e-01 | 87.9% | 72.7% |
| 5060019 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.69 | 60.0 | 5.26e-01 | 96.6% | 76.5% |
| 3591753 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.69 | 58.0 | 4.36e-01 | 94.8% | 55.2% |
| 4034431 | 632.15.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › CompInhib_SCIN | 0.68 | 56.0 | 4.99e-01 | 93.1% | 71.4% |
| 5031855 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.65 | 56.0 | 5.08e-01 | 98.3% | 82.5% |
| 5059279 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.64 | 52.0 | 4.74e-01 | 93.1% | 71.2% |
| 4549209 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.62 | 53.0 | 4.20e-01 | 100.0% | 48.5% |
| 3576658 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.62 | 49.0 | 5.05e-01 | 87.9% | 89.1% |
| 5060144 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.61 | 51.0 | 4.88e-01 | 96.6% | 84.3% |
| 3722247 | 568.1.1.4 ↗ | few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related › CHCH | 0.61 | 43.0 | 4.74e-01 | 89.7% | 95.6% |
| 5045525 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.61 | 51.0 | 4.35e-01 | 100.0% | 88.6% |
| 3285148 | 3730.1.1.5 ↗ | alpha arrays › CCM3/GCKIII dimerization domain › CCM3/GCKIII dimerization domain › CCM3/GCKIII dimerization domain › DUF6247 | 0.61 | 47.0 | 4.88e-01 | 93.1% | 92.7% |
| 3611276 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.61 | 44.0 | 3.69e-01 | 94.8% | 45.0% |
| 2439590 | 109.51.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › TssA helical domains › TssA helical domains | 0.60 | 40.0 | 3.89e-01 | 70.7% | 63.8% |
| 4959130 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.60 | 49.0 | 4.65e-01 | 93.1% | 81.4% |
| 3514703 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.60 | 48.0 | 4.45e-01 | 94.8% | 90.0% |
| 3415519 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 43.0 | 2.89e-01 | 79.3% | 37.5% |
| 5046679 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.59 | 49.0 | 4.64e-01 | 94.8% | 88.6% |
| 2792048 | 106.1.1.4 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Rsbr_N | 0.58 | 51.0 | 3.88e-01 | 100.0% | 70.4% |
| 3658301 | 3860.1.1.249 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › NFD4_C | 0.58 | 42.0 | 2.89e-01 | 79.3% | 21.4% |
| 4653158 | 1107.1.1.1 ↗ | alpha bundles › Pilin › Pilin › Pilin › TraA | 0.57 | 43.0 | 4.26e-01 | 89.7% | 76.6% |
| 3280908 | 4274.1.1.5 ↗ | extended segments › Transmembrane helices in MalF N-terminal region › Transmembrane helices in MalF N-terminal region › Transmembrane helices in MalF N-terminal region › PF28792 | 0.57 | 44.0 | 4.44e-01 | 87.9% | 83.3% |
| 3200806 | 109.4.1.15 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS | 0.52 | 43.0 | 3.45e-01 | 91.4% | 50.4% |
D3
medium
residues 212-266
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tfkB00 | 1.20.120.650 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D | 0.72 | 56.0 | 4.91e-01 | 87.3% | 64.0% |
| 3rk6A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 58.0 | 3.95e-01 | 100.0% | 36.4% |
| 4hteA03 | 1.10.167.30 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › | 0.66 | 46.0 | 4.10e-01 | 74.5% | 52.5% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.65 | 49.0 | 3.49e-01 | 83.6% | 52.8% |
| 1bh9B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.65 | 36.0 | 3.01e-01 | 94.5% | 33.7% |
| 2hytA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 52.0 | 3.65e-01 | 96.4% | 52.8% |
| 4bvxA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 50.0 | 4.31e-01 | 100.0% | 89.5% |
| 3i7aA00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.61 | 50.0 | 3.21e-01 | 94.5% | 71.0% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 47.0 | 4.05e-01 | 100.0% | 90.6% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.58 | 46.0 | 4.41e-01 | 90.9% | 87.7% |
| 5ojcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 48.0 | 3.52e-01 | 100.0% | 92.9% |
| 1lxlA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.55 | 45.0 | 3.13e-01 | 100.0% | 34.4% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 43.0 | 3.64e-01 | 92.7% | 58.6% |
| 3oymA01 | 1.10.340.70 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.52 | 40.0 | 3.40e-01 | 85.5% | 57.0% |
| 2qv6B02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.51 | 42.0 | 3.41e-01 | 100.0% | 67.2% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5052667 | 109.4.1.190 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6 | 0.85 | 70.0 | 5.06e-01 | 87.3% | 50.7% |
| 3521311 | 109.4.1.3048 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, HEAT_EZ, Importin_rep_4, TPR_IMB1, TPR_IPO5 | 0.82 | 72.0 | 3.95e-01 | 94.5% | 14.0% |
| 4002063 | 109.4.1.1593 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, HEAT_EZ, Importin_rep_4, Importin_rep_5, Importin_rep_6, TPR_IMB1, TPR_IPO5 | 0.81 | 70.0 | 3.74e-01 | 94.5% | 9.7% |
| 3867474 | 109.6.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF,RasGEF_N | 0.76 | 63.0 | 3.69e-01 | 92.7% | 13.8% |
| 3373701 | 109.4.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm | 0.73 | 65.0 | 3.79e-01 | 100.0% | 36.9% |
| 3925476 | 109.4.1.1134 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_INTS8_3 | 0.72 | 64.0 | 3.78e-01 | 96.4% | 19.5% |
| 2738699 | 109.4.1.1125 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TAF2_C | 0.71 | 61.0 | 5.49e-01 | 100.0% | 81.0% |
| 3172208 | 109.4.1.1298 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fes1, PF28415 | 0.70 | 62.0 | 3.89e-01 | 98.2% | 50.3% |
| 3931621 | 109.4.1.77 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › AAR2 | 0.69 | 59.0 | 4.28e-01 | 98.2% | 48.1% |
| 3183312 | 109.4.1.957 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TTI1_N | 0.67 | 57.0 | 3.44e-01 | 100.0% | 20.5% |
| 3634846 | 109.4.1.1672 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PUF, CPL | 0.63 | 53.0 | 3.07e-01 | 98.2% | 14.0% |
| 3734143 | 2004.1.1.473 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11 | 0.56 | 44.0 | 2.61e-01 | 98.2% | 10.2% |
| 4344201 | 864.1.1.0 ↗ | a+b two layers › DLC › DLC › DLC | 0.54 | 40.0 | 3.48e-01 | 80.0% | 50.0% |
| 3504389 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.54 | 37.0 | 3.33e-01 | 72.7% | 68.8% |
| 3501945 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.52 | 36.0 | 3.49e-01 | 74.5% | 84.6% |
D4
medium
residues 430-453_571-604_703-720
Domain cluster:
representative
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3625780 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.61 | 50.0 | 3.72e-01 | 92.1% | 70.4% |
| 3931851 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.59 | 51.0 | 3.49e-01 | 96.1% | 43.0% |
| 3708776 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.59 | 45.0 | 2.96e-01 | 82.9% | 70.2% |
| 3175731 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.58 | 41.0 | 2.33e-01 | 75.0% | 58.3% |
D5
medium
residues 454-472_605-624_668-702
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 38.0 | 3.75e-01 | 74.3% | 46.9% |
| 2yi9A05 | 1.20.1270.270 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › VP1, C-terminal extension domain | 0.62 | 35.0 | 3.46e-01 | 83.8% | 50.6% |
| 2kvsA00 | 1.10.150.260 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › YozE SAM-like | 0.61 | 43.0 | 4.24e-01 | 74.3% | 85.0% |
| 2fexA00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.61 | 43.0 | 3.19e-01 | 73.0% | 92.5% |
| 3b4sA01 | 1.10.287.790 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › luxt domain from vibrio parahaemolyticus | 0.60 | 38.0 | 4.34e-01 | 73.0% | 95.9% |
| 2lpbA00 | 1.10.287.2920 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 45.0 | 4.42e-01 | 89.2% | 77.8% |
| 4jgiA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.55 | 39.0 | 3.84e-01 | 75.7% | 87.5% |
| 2gf2A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.53 | 37.0 | 3.04e-01 | 73.0% | 79.1% |
| 2mw8A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.52 | 36.0 | 3.83e-01 | 73.0% | 82.1% |
| 1vw4L01 | 3.90.1030.10 | Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 | 0.52 | 34.0 | 2.80e-01 | 70.3% | 37.0% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3686609 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.58 | 41.0 | 3.89e-01 | 74.3% | 96.7% |
| 141918 | 101.1.2.49 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C | 0.58 | 41.0 | 3.07e-01 | 73.0% | 94.7% |
| 4983597 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 32.0 | 3.37e-01 | 70.3% | 56.9% |
| 4965486 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.57 | 38.0 | 3.28e-01 | 70.3% | 70.4% |
| 4437800 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.57 | 39.0 | 3.38e-01 | 71.6% | 67.8% |
| 4952255 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.56 | 38.0 | 3.25e-01 | 71.6% | 91.5% |
| 4202056 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.55 | 38.0 | 3.31e-01 | 73.0% | 93.3% |
| 4096162 | 103.2.1.2 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone | 0.55 | 43.0 | 3.89e-01 | 85.1% | 95.0% |
| 53246 | 129.1.1.0 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.54 | 37.0 | 3.20e-01 | 73.0% | 91.1% |
| 4952257 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.53 | 34.0 | 3.14e-01 | 90.5% | 47.1% |
| 3373978 | 5055.1.1.0 ↗ | extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel | 0.51 | 36.0 | 3.43e-01 | 74.3% | 82.2% |
| 5042372 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.51 | 35.0 | 3.25e-01 | 74.3% | 63.5% |
| 4684 | 192.15.1.2 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r | 0.51 | 32.0 | 3.40e-01 | 74.3% | 72.3% |
D6
medium
residues 493-510_554-570_880-975
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ntcA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.63 | 27.0 | 3.21e-01 | 90.1% | 54.9% |
| 2ktmA00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.62 | 33.0 | 4.33e-01 | 86.3% | 98.5% |
| 2blfB01 | 1.10.760.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain | 0.58 | 23.0 | 3.05e-01 | 79.4% | 65.1% |
| 1dp3A00 | 1.10.10.450 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › TraM protein, DNA-binding | 0.55 | 22.0 | 3.15e-01 | 85.5% | 81.8% |
| 6t0bc01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 25.0 | 3.12e-01 | 86.3% | 70.5% |
| 3u5nA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.51 | 28.0 | 2.93e-01 | 90.8% | 56.7% |
| 1ibcB00 | 3.30.70.1470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Caspase-like | 0.51 | 21.0 | 2.50e-01 | 72.5% | 51.1% |
| 4iz6B03 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.50 | 23.0 | 2.91e-01 | 79.4% | 71.1% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4016157 | 6026.1.1.1 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 | 0.61 | 23.0 | 2.36e-01 | 84.7% | 32.6% |
| 3378831 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.58 | 33.0 | 3.56e-01 | 94.7% | 65.5% |
| 5002969 | 3456.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › Oxidored_q4 | 0.56 | 22.0 | 2.31e-01 | 85.5% | 36.0% |
| 4633929 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.56 | 31.0 | 3.68e-01 | 86.3% | 77.8% |
| 3945220 | 4018.1.1.2 ↗ | a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P | 0.52 | 30.0 | 2.98e-01 | 86.3% | 50.3% |
| 1300152 | 191.1.1.47 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_45 | 0.50 | 32.0 | 3.24e-01 | 88.5% | 61.8% |
D7
medium
residues 511-553_976-994
D8
medium
residues 995-1114