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RNA-dependent_RNA_polymerases

Euk-Vir

Sclerotinia_sclerotiorum_mitovirus_2

RNA-dependent_RNA_polymerases__YP_009551566__Sclerotinia_sclerotiorum_mitovirus_2__1133728

Identity

Accession:
YP_009551566 ↗
Protein ID:
RNA-dependent_RNA_polymerases
Kingdom:
euk

Quality

68.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-117
PDB
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vhnA02 1.10.1200.80 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 0.65 33.0 4.10e-01 80.9% 78.9%
1abvA00 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.58 45.0 4.66e-01 80.9% 93.3%
1m2vB01 1.20.120.730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain 0.58 47.0 4.06e-01 87.8% 57.4%
3dzaA01 1.20.120.1940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain 0.57 37.0 3.69e-01 77.4% 63.2%
3sqnA02 1.10.1790.40 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › 0.57 35.0 3.54e-01 100.0% 59.3%
6v0kA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 42.0 3.17e-01 80.0% 50.3%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.56 45.0 4.78e-01 90.4% 99.0%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.55 43.0 3.99e-01 100.0% 64.9%
3wa8B00 1.10.520.40 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › CRISPR-associated protein Cse2 0.54 41.0 3.57e-01 85.2% 52.6%
2fiqA02 1.10.400.20 Mainly Alpha › Orthogonal Bundle › GI Alpha 1, domain 2-like › putative tagatose 6-phosphate kinase domain like 0.53 32.0 3.13e-01 77.4% 54.8%
3q2qA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.53 43.0 3.09e-01 93.9% 31.5%
1wp9B03 1.20.1320.20 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › hef helicase domain 0.52 47.0 4.58e-01 100.0% 89.2%
4gytA00 1.20.120.740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 0.52 40.0 3.49e-01 82.6% 80.2%
1xdzA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 39.0 3.17e-01 81.7% 89.5%
2xq0A03 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.51 43.0 3.87e-01 90.4% 99.4%
3h38A02 1.10.3090.10 Mainly Alpha › Orthogonal Bundle › cca-adding enzyme, domain 2 › cca-adding enzyme, domain 2 0.50 39.0 2.99e-01 81.7% 43.4%
3d85C00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 35.0 3.32e-01 70.4% 99.2%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1487362 3930.2.1.1 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in endoribonuclease Dicer › Helical bundle in endoribonuclease Dicer › Dicer_PBD 0.69 50.0 4.96e-01 100.0% 73.1%
3652633 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.66 56.0 5.39e-01 100.0% 80.0%
3508664 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.63 51.0 5.14e-01 100.0% 87.0%
3428665 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 42.0 3.59e-01 84.3% 43.9%
3576637 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.62 40.0 3.72e-01 84.3% 52.4%
3574876 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.61 41.0 3.89e-01 85.2% 58.5%
4058294 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.61 51.0 4.87e-01 93.0% 96.3%
3226210 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.59 45.0 3.07e-01 100.0% 23.0%
4944891 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.59 42.0 3.48e-01 73.0% 65.0%
4080077 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.59 46.0 4.81e-01 84.3% 100.0%
5054990 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 40.0 3.81e-01 85.2% 60.1%
4889198 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.57 45.0 3.95e-01 84.3% 78.4%
3982121 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 39.0 3.43e-01 85.2% 46.9%
3718891 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.55 38.0 3.49e-01 84.3% 52.9%
3710878 1147.1.1.2 alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › FWWh 0.54 37.0 2.97e-01 84.3% 35.2%
3585345 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.52 46.0 3.57e-01 100.0% 82.2%
3505833 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 40.0 3.42e-01 84.3% 70.3%
3279461 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 40.0 3.31e-01 84.3% 70.5%
D2 medium residues 118-268_328-352
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 58.7 7.80e-16 67.6% 21.7%
D3 medium residues 269-327_353-442
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 143.7 1.30e-41 62.4% 18.1%
PF05919.17 Mitovir_RNA_pol 59.5 4.60e-16 40.3% 12.5%
D4 medium residues 443-552
PDB
D5 medium residues 553-639
PDB