←Back to structures

RNA_dependent_RNA_polymerase

Euk-Vir

Pepino_mosaic_virus

RNA_dependent_RNA_polymerase__NP_663724__Pepino_mosaic_virus__112229

Identity

Accession:
NP_663724 ↗
Protein ID:
RNA_dependent_RNA_polymerase
Kingdom:
euk

Quality

72.8 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Tymovirales› Alphaflexiviridae› Potexvirus› Pepino_mosaic_virus

TaxID: 112229

Cluster

View cluster (13 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 276-402
PDB
Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_009091814__Yam_virus_X__1503864__D297-399
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01660.23 best Vmethyltransf 33.1 4.70e-08 40.9% 16.7%
D2 medium residues 11-68_459-486
PDB
D3 medium residues 69-176
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01660.23 best Vmethyltransf 96.4 2.40e-27 100.0% 40.8%
CATH (86)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ej6A04 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 67.0 5.13e-01 100.0% 93.5%
6qp2A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.68 59.0 4.57e-01 93.5% 47.4%
3fkdA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.68 56.0 4.44e-01 92.6% 44.4%
1iayA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.68 58.0 4.43e-01 93.5% 46.4%
3fdbA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.67 58.0 4.59e-01 93.5% 48.4%
3dnfA02 3.40.50.11270 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 49.0 5.45e-01 95.4% 100.0%
3ffhB02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.66 57.0 4.53e-01 92.6% 50.0%
1jx6A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 57.0 5.11e-01 94.4% 74.8%
3f0hA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 58.0 4.31e-01 96.3% 39.5%
1svvA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 59.0 4.52e-01 100.0% 67.2%
2x5fA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 57.0 4.06e-01 96.3% 35.6%
5z0qA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 57.0 4.50e-01 96.3% 49.1%
2k4mA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 58.0 5.15e-01 97.2% 69.3%
1bwpA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.65 50.0 3.97e-01 80.6% 47.2%
8ffuA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 56.0 4.41e-01 96.3% 46.2%
6g80B01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 58.0 4.62e-01 100.0% 74.2%
1m32A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 57.0 4.35e-01 96.3% 43.9%
5ej8A03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.65 55.0 4.47e-01 95.4% 48.6%
3getA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.65 55.0 4.30e-01 92.6% 46.1%
2o4cA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 56.0 4.84e-01 94.4% 70.5%
4dzrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 57.0 5.01e-01 100.0% 72.4%
3f6tA03 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.64 56.0 4.42e-01 96.3% 52.7%
2dr1A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.64 55.0 4.27e-01 96.3% 44.3%
2fwrA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 57.0 4.84e-01 99.1% 62.4%
1cl1A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.63 55.0 4.22e-01 96.3% 40.9%
7e7gA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.63 57.0 4.31e-01 99.1% 62.5%
3ezsA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.63 54.0 4.25e-01 96.3% 44.4%
3hs3A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 55.0 5.10e-01 96.3% 80.4%
1ibjA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.63 53.0 4.08e-01 92.6% 41.4%
6f35A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 54.0 4.29e-01 96.3% 48.7%
4iw7A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 50.0 3.99e-01 96.3% 42.7%
3nx3A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 53.0 4.05e-01 92.6% 49.8%
3dnfA03 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.62 51.0 5.33e-01 96.3% 99.0%
8sl7B01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 53.0 4.10e-01 96.3% 51.9%
2jfnA02 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 53.0 5.20e-01 92.6% 100.0%
6lpiD03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.62 52.0 4.54e-01 94.4% 60.1%
7u7hA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 54.0 4.26e-01 96.3% 48.0%
3k4hA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 52.0 4.81e-01 94.4% 81.0%
4c4aA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 54.0 4.96e-01 98.1% 93.1%
1mzvA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 55.0 4.41e-01 100.0% 70.8%
4zeoH02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.61 55.0 4.80e-01 98.1% 82.5%
5gzjB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 54.0 4.54e-01 99.1% 98.9%
2vbiA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.61 53.0 4.41e-01 96.3% 54.5%
3a11B02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.61 53.0 4.40e-01 96.3% 65.5%
7tlrA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 55.0 4.18e-01 100.0% 51.6%
2c81A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 52.0 4.06e-01 96.3% 41.9%
3gvpA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 52.0 4.56e-01 93.5% 68.6%
1nytA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 51.0 4.69e-01 94.4% 97.9%
2ocaA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 53.0 4.34e-01 99.1% 63.5%
5vogA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 53.0 4.57e-01 100.0% 71.0%
1c8bA00 3.40.50.1450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HybD-like 0.60 54.0 3.87e-01 100.0% 50.6%
2ht1A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 53.0 4.24e-01 99.1% 63.1%
3e1sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 52.0 4.18e-01 99.1% 48.6%
4ix1A00 3.40.50.12500 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 53.0 4.17e-01 100.0% 68.4%
7pt4A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.60 52.0 4.29e-01 96.3% 58.8%
5t3oA02 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 50.0 4.67e-01 94.4% 91.4%
6b4kB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 52.0 4.54e-01 99.1% 73.5%
3hwwA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.59 52.0 4.26e-01 99.1% 52.0%
1ve5C02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 33.0 4.14e-01 95.4% 100.0%
7r7jB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 51.0 4.56e-01 97.2% 75.5%
1sazA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 50.0 4.17e-01 94.4% 89.3%
1pjqA04 3.40.1010.10 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › Tetrapyrrole methylase, N-terminal domain 0.59 50.0 4.99e-01 98.1% 90.4%
4k28A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 50.0 4.53e-01 93.5% 81.0%
5l3qA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 3.99e-01 92.6% 53.9%
4kxvA02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.58 49.0 4.10e-01 96.3% 52.6%
3s5jA02 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 49.0 4.57e-01 94.4% 88.3%
2r5fA00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 51.0 4.10e-01 100.0% 71.6%
1vchD00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 51.0 4.39e-01 100.0% 92.5%
2qbyA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 50.0 4.35e-01 100.0% 97.7%
3rc3A03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 51.0 4.48e-01 98.1% 72.3%
1m6nA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 49.0 4.26e-01 99.1% 75.9%
3i4jB02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 50.0 3.88e-01 100.0% 48.2%
4c7oA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 48.0 3.99e-01 94.4% 58.2%
3ca8A02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.56 48.0 4.32e-01 96.3% 87.7%
2amlA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.56 49.0 4.44e-01 99.1% 72.1%
3bchA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.55 49.0 4.11e-01 100.0% 68.8%
2z1dA01 3.40.50.11750 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HypD, alpha/beta domain 1 0.53 46.0 4.27e-01 96.3% 95.7%
1pswA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.53 43.0 3.77e-01 99.1% 56.8%
3p2mA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 44.0 3.36e-01 96.3% 87.5%
3rojA02 3.40.190.90 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.52 42.0 3.73e-01 91.7% 59.3%
3h3eA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.52 44.0 3.45e-01 98.1% 85.5%
4finB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 3.48e-01 100.0% 65.5%
3cpgA00 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.51 45.0 3.50e-01 100.0% 96.8%
1in4A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 4.07e-01 100.0% 89.9%
2iw3A04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 45.0 3.53e-01 99.1% 62.1%
3qhqB01 3.40.50.11940 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 44.0 3.97e-01 98.1% 71.8%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3802438 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.68 62.0 4.79e-01 100.0% 48.9%
4991830 2004.1.1.146 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.68 61.0 4.99e-01 98.1% 59.6%
3976871 2007.1.10.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › PrpR receptor domain-like › PrpR_N 0.67 56.0 4.04e-01 100.0% 32.9%
3805802 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.67 59.0 4.77e-01 97.2% 55.1%
3953351 7577.1.1.1 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 0.66 60.0 4.29e-01 100.0% 58.1%
4315439 2007.1.5.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.66 59.0 4.39e-01 100.0% 62.7%
4480131 2007.1.10.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › PrpR receptor domain-like › PF29746 0.65 52.0 5.46e-01 97.2% 96.8%
4468204 2007.1.5.11 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › PF29746 0.65 50.0 5.43e-01 92.6% 100.0%
3390077 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.65 56.0 4.92e-01 94.4% 63.7%
4087872 7577.1.1.1 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 0.64 58.0 4.19e-01 100.0% 57.7%
4886087 2003.1.11.7 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Formate/glycerate dehydrogenase catalytic domain-like › 2-Hacid_dh_C 0.64 57.0 4.86e-01 96.3% 68.8%
4481335 2003.1.1.37 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.64 57.0 4.76e-01 96.3% 65.0%
3375228 7573.1.1.4 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › UPRTase 0.64 58.0 4.64e-01 100.0% 60.6%
3962500 2004.1.1.220 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2 0.64 57.0 4.57e-01 99.1% 67.4%
4263325 7574.1.1.0 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.64 55.0 4.59e-01 96.3% 54.2%
4522625 7577.1.1.3 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.64 57.0 4.23e-01 100.0% 61.1%
5012244 2007.1.5.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › Amdase 0.63 56.0 4.92e-01 99.1% 86.1%
5037032 7577.1.1.1 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 0.63 57.0 4.35e-01 100.0% 62.0%
4954366 7577.1.1.1 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 0.63 57.0 4.40e-01 100.0% 66.7%
5062564 2007.24.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › AtpF-like › AtpF-like › ATP-synt_F 0.63 46.0 5.09e-01 80.6% 97.6%
3484555 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.63 54.0 4.64e-01 96.3% 58.9%
3384248 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.62 56.0 4.56e-01 100.0% 56.6%
3635122 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.62 56.0 4.14e-01 100.0% 80.0%
3397160 2007.1.2.30 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › IR75A_N 0.62 54.0 4.64e-01 98.1% 60.0%
4411250 7574.1.1.0 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.62 53.0 4.52e-01 96.3% 57.0%
3937308 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.62 55.0 4.12e-01 100.0% 45.8%
3733478 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.61 54.0 4.18e-01 100.0% 75.3%
4934845 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.61 47.0 5.04e-01 82.4% 100.0%
3599830 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 53.0 4.17e-01 100.0% 77.6%
3282192 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.61 54.0 4.64e-01 100.0% 79.4%
3962964 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.61 53.0 4.46e-01 100.0% 55.8%
3432433 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 54.0 4.20e-01 99.1% 57.5%
4999245 7577.1.1.3 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.61 54.0 3.96e-01 100.0% 53.0%
4581964 2004.1.1.28 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK 0.61 54.0 4.64e-01 98.1% 79.4%
3670204 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.61 54.0 4.19e-01 100.0% 48.2%
3955660 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 54.0 4.07e-01 99.1% 62.3%
3610585 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 53.0 4.02e-01 100.0% 76.0%
3266443 7574.1.1.5 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.60 52.0 4.25e-01 97.2% 53.8%
3213692 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.60 51.0 4.38e-01 92.6% 59.4%
5050282 7584.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.60 53.0 4.32e-01 100.0% 55.7%
4409035 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.60 51.0 4.61e-01 95.4% 94.7%
5026753 4978.1.1.1 ↗ a/b three-layered sandwiches › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › tRNA_deacylase 0.59 45.0 4.86e-01 80.6% 97.8%
4069467 4978.1.1.1 ↗ a/b three-layered sandwiches › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › tRNA_deacylase 0.59 44.0 4.75e-01 78.7% 95.6%
5053615 7584.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.59 53.0 4.42e-01 100.0% 62.6%
4973340 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.59 46.0 3.82e-01 82.4% 50.3%
10667 7573.1.1.0 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like 0.59 52.0 4.56e-01 100.0% 92.9%
4937463 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.59 52.0 5.07e-01 100.0% 93.3%
4979003 7584.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins 0.58 52.0 4.52e-01 100.0% 64.1%
4967991 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 52.0 4.23e-01 100.0% 74.8%
3352911 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.58 52.0 4.44e-01 100.0% 66.3%
3287973 7577.1.1.1 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 0.58 52.0 3.57e-01 100.0% 41.3%
3989781 3110.1.1.18 ↗ a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF29470 0.58 50.0 5.01e-01 99.1% 95.6%
3926234 323.1.1.0 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.58 51.0 4.07e-01 100.0% 52.4%
3603150 2004.1.1.220 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2 0.58 51.0 4.04e-01 100.0% 77.8%
4546415 7588.1.1.1 ↗ a/b three-layered sandwiches › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › LYTB 0.57 51.0 5.04e-01 99.1% 92.2%
3957590 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 52.0 4.64e-01 100.0% 72.0%
4182424 2004.1.1.360 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NTE_Ploop 0.57 45.0 3.85e-01 85.2% 87.8%
3286186 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 49.0 4.39e-01 100.0% 66.5%
None — 0.57 47.0 4.29e-01 91.7% 66.7%
3741638 2007.2.5.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.57 43.0 4.37e-01 92.6% 81.9%
4943654 7594.1.1.1 ↗ a/b three-layered sandwiches › Hydrogenase expression/formation protein HypD › Hydrogenase expression/formation protein HypD › Hydrogenase expression/formation protein HypD › HypD 0.57 49.0 4.09e-01 99.1% 70.2%
3996625 2004.1.1.186 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.56 48.0 4.44e-01 97.2% 91.4%
3255681 2007.1.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.56 45.0 4.29e-01 87.0% 74.4%
3413049 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 49.0 3.58e-01 100.0% 42.2%
4870619 2003.1.7.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B 0.56 45.0 4.11e-01 86.1% 79.3%
3434867 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.55 39.0 2.75e-01 73.1% 30.7%
4033946 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 48.0 4.25e-01 100.0% 65.8%
4223384 7579.1.1.6 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.55 41.0 2.97e-01 79.6% 79.1%
4604367 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.55 46.0 4.36e-01 94.4% 85.2%
5027609 2004.1.1.196 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.55 48.0 4.09e-01 100.0% 85.9%
4929541 2007.1.14.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA 0.55 46.0 4.36e-01 96.3% 78.5%
3489109 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.55 48.0 3.70e-01 100.0% 81.9%
3932941 2004.1.1.23 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.54 47.0 3.52e-01 97.2% 57.1%
4027753 323.1.1.0 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.54 48.0 4.13e-01 100.0% 77.1%
4289471 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.54 46.0 3.24e-01 96.3% 90.2%
3225403 207.1.1.104 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_Zer-1 0.54 41.0 2.99e-01 79.6% 39.3%
5051856 7528.1.1.3 ↗ a/b three-layered sandwiches › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › PGM_PMM_III 0.54 44.0 4.20e-01 100.0% 76.8%
3466240 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 45.0 3.86e-01 97.2% 63.7%
3224330 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 44.0 4.14e-01 96.3% 82.9%
3438436 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.52 37.0 2.82e-01 74.1% 43.8%
None — 0.52 46.0 3.96e-01 100.0% 84.6%
None — 0.52 45.0 3.90e-01 100.0% 82.2%
None — 0.52 45.0 3.96e-01 100.0% 87.1%
None — 0.52 45.0 4.04e-01 100.0% 92.5%
None — 0.51 45.0 3.93e-01 100.0% 87.1%
4996142 7512.1.1.12 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_tran_28_C 0.51 38.0 3.34e-01 98.1% 49.7%
4989999 2004.1.1.308 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 0.51 46.0 4.01e-01 99.1% 73.2%
5057591 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.51 45.0 4.22e-01 100.0% 94.8%
5027337 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 42.0 3.98e-01 91.7% 100.0%
5061424 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.51 45.0 3.75e-01 100.0% 81.0%
5011535 2006.1.1.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.50 43.0 3.47e-01 100.0% 82.1%
D4 medium residues 222-263_405-417_448-458
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01660.23 best Vmethyltransf 27.9 1.70e-06 98.5% 13.2%
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1sezA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.62 47.0 3.42e-01 81.8% 32.2%
1x51A01 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.61 42.0 3.31e-01 72.7% 93.7%
1ig8A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 47.0 3.77e-01 86.4% 97.0%
1of5A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 42.0 3.18e-01 74.2% 51.3%
3mdqA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 46.0 3.74e-01 84.8% 85.4%
1c44A00 3.30.1050.10 Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain 0.58 50.0 4.12e-01 98.5% 76.4%
1bdgA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.58 47.0 3.55e-01 90.9% 96.3%
7kx7A03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.57 44.0 3.21e-01 89.4% 92.1%
2x36D00 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.56 41.0 3.16e-01 83.3% 98.3%
4nurA03 3.30.1050.10 Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain 0.56 47.0 3.81e-01 95.5% 62.6%
3qfgA00 2.60.40.1240 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 41.0 3.20e-01 80.3% 87.6%
4axhA03 3.30.1050.10 Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain 0.54 44.0 3.54e-01 89.4% 62.5%
2c9jA00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.54 43.0 3.12e-01 92.4% 47.9%
5tkwA01 3.30.420.380 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.52 40.0 3.08e-01 87.9% 78.2%
3nzkA01 3.30.230.20 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › lpxc deacetylase, domain 1 0.51 43.0 3.57e-01 98.5% 94.5%
3f1tB00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.51 45.0 3.57e-01 98.5% 92.6%
3ei3A02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 40.0 2.63e-01 89.4% 22.3%
4hfqA02 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.51 37.0 3.01e-01 78.8% 78.4%
1w0pA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 41.0 3.10e-01 92.4% 69.5%
1gydB00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.50 42.0 2.82e-01 100.0% 87.9%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3767654 2484.1.1.176 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 0.64 52.0 3.17e-01 92.4% 86.4%
4222724 5.1.4.169 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RSE1_2nd 0.62 49.0 3.09e-01 86.4% 76.9%
3436743 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.62 52.0 3.38e-01 95.5% 25.0%
3429037 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.62 52.0 3.37e-01 95.5% 24.6%
3877730 2484.1.1.5 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1 0.62 50.0 3.48e-01 90.9% 68.7%
4156379 2484.1.1.41 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK 0.60 46.0 3.47e-01 83.3% 77.0%
3719066 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.60 51.0 3.47e-01 95.5% 73.3%
3417283 7516.1.1.16 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_43 0.60 45.0 2.99e-01 83.3% 61.4%
3908854 2484.1.1.215 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27041 0.59 46.0 2.81e-01 87.9% 75.5%
3619778 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.59 45.0 2.93e-01 81.8% 31.4%
4981234 896.1.1.0 ↗ a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.58 40.0 4.12e-01 72.7% 92.3%
3229203 2484.1.1.50 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Dimer_Tnp_hAT 0.58 47.0 2.82e-01 89.4% 76.0%
3693329 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 46.0 3.25e-01 89.4% 96.8%
3463741 7516.1.1.16 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_43 0.57 44.0 2.91e-01 83.3% 53.3%
3437841 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.57 46.0 2.95e-01 90.9% 22.2%
3991950 2484.1.1.176 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 0.57 47.0 2.84e-01 93.9% 86.1%
4606510 4263.2.1.0 ↗ a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain 0.56 41.0 3.78e-01 77.3% 76.5%
3800831 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 46.0 2.81e-01 93.9% 82.1%
3315619 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 45.0 3.00e-01 93.9% 24.8%
4941861 244.3.1.1 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › SufE/NifU › SufE/NifU › NifU_N 0.55 38.0 3.12e-01 72.7% 86.4%
4365245 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.55 44.0 3.58e-01 87.9% 76.0%
3739109 221.4.1.9 ↗ a+b two layers › beta-Grasp › Nudix › Nudix › NUDIX_4 0.55 40.0 3.16e-01 78.8% 80.0%
4010765 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.54 42.0 3.50e-01 87.9% 80.8%
4045725 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.54 42.0 3.53e-01 89.4% 80.8%
4439294 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.54 44.0 3.58e-01 90.9% 85.6%
4144742 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.53 43.0 3.61e-01 90.9% 84.2%
4369846 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.53 44.0 3.63e-01 90.9% 85.0%
3933646 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.53 41.0 3.62e-01 84.8% 89.0%
5007973 268.1.1.1 ↗ a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related › SCP2 0.53 43.0 3.59e-01 87.9% 69.3%
3386148 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.53 42.0 3.54e-01 90.9% 86.7%
4098000 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.52 40.0 3.38e-01 86.4% 75.0%
4442902 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.52 40.0 3.34e-01 87.9% 83.2%
3745492 2484.1.1.176 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 0.52 41.0 2.35e-01 93.9% 42.7%
4037664 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.52 42.0 3.45e-01 90.9% 83.2%
4945648 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.52 37.0 3.19e-01 74.2% 77.7%
3220601 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 42.0 2.58e-01 97.0% 69.9%
3507047 244.4.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › Ni-Fe binding domain in nickel-iron hydrogenase large subunit 0.51 39.0 3.43e-01 83.3% 96.0%
3412288 298.1.1.6 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › G6PD_C 0.50 40.0 2.68e-01 92.4% 64.5%
4636438 2484.1.1.174 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.50 38.0 3.25e-01 86.4% 83.3%
D5 medium residues 487-508_1017-1054_1105-1169_1247-1278
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009389473__Vanilla_latent_virus__2016426__D1017-1094_1185-1232
D6 medium residues 1190-1230_1279-1341
PDB
Domain cluster: rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
D7 medium residues 1342-1439
PDB
Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_009091814__Yam_virus_X__1503864__D1288-1359