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RNA_dependent_RNA_polymerase

Euk-Vir

Clitocybe_odora_virus

RNA_dependent_RNA_polymerase__YP_005352912__Clitocybe_odora_virus__1162083

Identity

Accession:
YP_005352912 ↗
Protein ID:
RNA_dependent_RNA_polymerase
Kingdom:
euk

Quality

50.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 59-187_563-580
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6ks6a01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.63 49.0 4.00e-01 83.0% 92.1%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.57 37.0 4.38e-01 98.0% 98.0%
6ks6G01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.56 48.0 4.02e-01 93.2% 95.4%
3kttB01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.56 50.0 4.17e-01 98.6% 99.2%
2z15A00 3.90.640.90 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › Anti-proliferative protein, N-terminal domain 0.55 42.0 4.66e-01 81.6% 99.2%
1m4rB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 39.0 4.01e-01 72.8% 87.2%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 34.0 3.91e-01 85.0% 88.1%
1puoB00 1.20.920.50 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.54 41.0 4.21e-01 78.9% 100.0%
3auxA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 34.0 2.55e-01 76.2% 27.3%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.51 37.0 3.99e-01 85.0% 86.7%
2nq2A00 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.51 45.0 3.60e-01 99.3% 84.7%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3933108 110.1.1.0 alpha arrays › DEATH domain › DEATH domain › DEATH domain 0.56 29.0 3.36e-01 76.9% 66.7%
3936362 192.5.1.21 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › TF_AP-2 0.54 34.0 3.64e-01 83.7% 72.3%
4929535 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.51 42.0 3.70e-01 87.1% 96.7%
4025329 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.50 40.0 4.16e-01 83.7% 91.9%
3633559 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 41.0 3.53e-01 85.7% 89.8%
3747865 5050.1.1.6 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP 0.50 40.0 3.19e-01 84.4% 83.8%
D2 medium residues 188-234_322-366_403-448
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 51.8 1.00e-13 61.6% 9.0%
PF05919.17 Mitovir_RNA_pol 28.8 9.40e-07 34.1% 8.5%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mukA02 3.90.1850.10 Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 0.73 68.0 4.50e-01 100.0% 58.8%
2r7rA05 1.10.357.80 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.67 61.0 5.64e-01 100.0% 96.0%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4434853 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.63 47.0 3.86e-01 76.8% 63.3%
4012111 812.2.1.0 a+b duplicates or obligate multimers › MinE-like › Cyanase C-terminal domain › Cyanase C-terminal domain 0.53 22.0 2.95e-01 91.3% 74.6%
3332006 101.1.2.245 alpha arrays › HTH › HTH › winged helix domain › PORR 0.52 29.0 3.05e-01 94.2% 58.3%
3804378 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.51 19.0 2.54e-01 72.5% 60.0%
D3 medium residues 235-321
PDB
D4 medium residues 367-402_449-542
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 113.8 1.60e-32 72.3% 17.9%
PF05919.17 Mitovir_RNA_pol 32.7 6.20e-08 27.7% 7.6%
D5 medium residues 543-562_581-616
PDB
D6 medium residues 842-1009
PDB