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RNA_dependent_RNA_polymerase
Euk-VirYam_virus_X
RNA_dependent_RNA_polymerase__YP_009091814__Yam_virus_X__1503864
Identity
- Accession:
- YP_009091814 ↗
- Protein ID:
- RNA_dependent_RNA_polymerase
- Kingdom:
- euk
Quality
75.9
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Tymovirales›
Alphaflexiviridae›
Potexvirus›
Yam_virus_X
TaxID: 1503864
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 579-750_766-773
Domain cluster:
rep: p39__YP_004928123__Hibiscus_green_spot_virus_2__1513278__D5-179
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01443.25 best | Viral_helicase1 | 97.0 | 2.20e-27 | 62.8% | 43.9% |
D2
high
residues 798-897
Domain cluster:
rep: TGB1_protein__NP_619560__Garlic_latent_virus__12458__D129-228
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01443.25 best | Viral_helicase1 | 56.9 | 3.80e-15 | 80.0% | 32.9% |
D3
medium
residues 1-66
D4
medium
residues 67-296_400-413
Domain cluster:
rep: uncovered_polypeptide_polyprotein__YP_001086452_0-758__Chrysanthemum_virus_B__12165__D72-292
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01660.23 best | Vmethyltransf | 220.4 | 4.40e-65 | 97.1% | 82.0% |
D5
medium
residues 297-399
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4h9nC00 | 1.20.58.2170 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 41.0 | 3.32e-01 | 72.8% | 42.9% |
| 7dluA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 38.0 | 3.82e-01 | 91.3% | 74.3% |
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.52 | 37.0 | 3.91e-01 | 97.1% | 81.9% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3570983 | 6103.1.1.1 ↗ | alpha bundles › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain › DAXX_hist_bd | 0.61 | 43.0 | 3.44e-01 | 72.8% | 41.9% |
| 3400571 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.57 | 43.0 | 3.86e-01 | 82.5% | 56.8% |
| 3731864 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.55 | 49.0 | 4.37e-01 | 100.0% | 94.7% |
| 4995358 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.54 | 38.0 | 3.87e-01 | 91.3% | 72.4% |
| 4970333 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.53 | 40.0 | 4.16e-01 | 92.2% | 87.4% |
| 3585555 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.52 | 41.0 | 3.05e-01 | 84.5% | 39.6% |
D6
medium
residues 1156-1287
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1k78I00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 20.0 | 2.88e-01 | 81.8% | 69.0% |
| 4zmuA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.50 | 38.0 | 3.64e-01 | 97.0% | 67.7% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 217141 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.80 | 76.0 | 5.35e-01 | 100.0% | 42.0% |
| 3989356 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.72 | 66.0 | 5.90e-01 | 100.0% | 77.3% |
| 3911603 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.72 | 63.0 | 5.86e-01 | 94.7% | 98.2% |
| 3674655 | 2003.1.9.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins | 0.71 | 60.0 | 3.89e-01 | 90.9% | 23.2% |
| 3935908 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.63 | 52.0 | 5.39e-01 | 97.0% | 93.6% |
| 3907339 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.58 | 48.0 | 3.94e-01 | 90.2% | 53.1% |
| 4600900 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 32.0 | 3.51e-01 | 98.5% | 71.4% |
D7
medium
residues 1288-1359
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ra1A02 | 1.20.58.780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 54.0 | 5.61e-01 | 83.3% | 100.0% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 59.0 | 5.50e-01 | 95.8% | 89.2% |
| 4malA00 | 1.20.58.2200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 47.0 | 5.08e-01 | 90.3% | 88.1% |
| 3pjaJ01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.66 | 53.0 | 4.41e-01 | 88.9% | 60.3% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 54.0 | 5.00e-01 | 94.4% | 94.7% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 53.0 | 4.83e-01 | 90.3% | 95.8% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 50.0 | 5.21e-01 | 98.6% | 100.0% |
| 2hqtK00 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 50.0 | 4.41e-01 | 91.7% | 59.8% |
| 4qreA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.63 | 50.0 | 3.86e-01 | 90.3% | 49.1% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 50.0 | 4.29e-01 | 97.2% | 53.8% |
| 1k8kG00 | 1.25.40.190 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 | 0.62 | 51.0 | 4.22e-01 | 95.8% | 48.9% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 53.0 | 4.85e-01 | 98.6% | 94.9% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.83e-01 | 91.7% | 91.8% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 50.0 | 5.04e-01 | 95.8% | 98.6% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 49.0 | 4.44e-01 | 98.6% | 93.6% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 47.0 | 4.29e-01 | 97.2% | 81.5% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.58 | 49.0 | 4.43e-01 | 98.6% | 68.9% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 45.0 | 4.07e-01 | 87.5% | 100.0% |
| 5i1uA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 42.0 | 2.80e-01 | 79.2% | 94.7% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 41.0 | 3.37e-01 | 81.9% | 76.2% |
| 5c9eB01 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.55 | 45.0 | 4.28e-01 | 91.7% | 81.6% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 44.0 | 3.99e-01 | 98.6% | 64.4% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.55 | 43.0 | 4.07e-01 | 93.1% | 71.3% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.54 | 46.0 | 4.12e-01 | 98.6% | 75.5% |
| 7xcnM01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.53 | 43.0 | 4.23e-01 | 88.9% | 88.5% |
| 3fhnA04 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.51 | 42.0 | 3.49e-01 | 91.7% | 70.2% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 42.0 | 3.45e-01 | 91.7% | 92.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3701020 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.73 | 62.0 | 6.07e-01 | 95.8% | 100.0% |
| 3504301 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 60.0 | 5.31e-01 | 98.6% | 92.7% |
| 4024628 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.69 | 52.0 | 5.27e-01 | 81.9% | 82.9% |
| 1806460 | 604.1.1.8 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SbsC_spectrin-like | 0.67 | 53.0 | 5.57e-01 | 91.7% | 98.4% |
| 3898855 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 53.0 | 4.50e-01 | 87.5% | 91.7% |
| 4000800 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.66 | 51.0 | 3.93e-01 | 83.3% | 42.4% |
| 3238399 | 109.4.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 | 0.65 | 55.0 | 4.70e-01 | 94.4% | 67.5% |
| 3456188 | 109.7.1.10 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › WAV3_C | 0.65 | 50.0 | 5.00e-01 | 94.4% | 82.7% |
| 3940812 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.64 | 55.0 | 4.83e-01 | 97.2% | 91.8% |
| 3785094 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.63 | 55.0 | 5.00e-01 | 100.0% | 89.0% |
| 2797699 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 52.0 | 4.69e-01 | 94.4% | 72.0% |
| 5027021 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.61 | 52.0 | 4.57e-01 | 98.6% | 80.0% |
| 4142324 | 109.4.1.228 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C | 0.61 | 52.0 | 3.71e-01 | 100.0% | 61.2% |
| 4241363 | 3636.1.1.0 ↗ | a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain | 0.60 | 49.0 | 3.66e-01 | 90.3% | 68.6% |
| 4586614 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.59 | 42.0 | 4.50e-01 | 86.1% | 91.7% |
| 3564606 | 604.1.1.60 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Stereocilin | 0.59 | 51.0 | 3.95e-01 | 100.0% | 80.0% |
| 4984709 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.59 | 47.0 | 4.59e-01 | 90.3% | 93.8% |
| 5001671 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.58 | 47.0 | 4.57e-01 | 91.7% | 93.8% |
| 5047897 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.58 | 47.0 | 4.52e-01 | 94.4% | 88.2% |
| 4989102 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.58 | 47.0 | 4.45e-01 | 94.4% | 85.6% |
| 3240456 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 49.0 | 4.69e-01 | 95.8% | 97.6% |
| 4947988 | 4995.1.1.5 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding | 0.57 | 45.0 | 4.44e-01 | 90.3% | 95.0% |
| 4939046 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.57 | 46.0 | 4.52e-01 | 94.4% | 91.3% |
| 4971674 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.56 | 46.0 | 4.48e-01 | 94.4% | 91.3% |
| 2814626 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.55 | 38.0 | 2.58e-01 | 72.2% | 17.0% |
| 5050707 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.55 | 44.0 | 4.39e-01 | 90.3% | 93.3% |
| 3612725 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.55 | 44.0 | 4.28e-01 | 93.1% | 85.9% |
| 5075377 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.55 | 45.0 | 4.28e-01 | 94.4% | 80.0% |
| 164355 | 172.1.1.1 ↗ | alpha complex topology › Citrate synthase-like › Citrate synthase › Citrate synthase › Citrate_synt | 0.54 | 45.0 | 2.92e-01 | 100.0% | 34.4% |
| 3237585 | 109.27.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain | 0.53 | 42.0 | 4.09e-01 | 90.3% | 78.5% |
| 3697679 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.52 | 47.0 | 3.03e-01 | 100.0% | 92.3% |
| 5044676 | 109.61.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Uncharacterized protein PF2048.1 › Uncharacterized protein PF2048.1 | 0.51 | 39.0 | 4.12e-01 | 80.6% | 100.0% |