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RNA_polymerase_RPB1_large_subunit
Euk-VirNoumeavirus
RNA_polymerase_RPB1_large_subunit__YP_009345156__Noumeavirus__1955558
Identity
- Accession:
- YP_009345156 ↗
- Protein ID:
- RNA_polymerase_RPB1_large_subunit
- Kingdom:
- euk
Quality
76.4
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Marseilleviridae›
Marseillevirus›
Noumeavirus
TaxID: 1955558
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 89-225
D2
high
residues 935-1023
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1f0jA00 | 1.10.1300.10 | Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 0.61 | 48.0 | 3.26e-01 | 87.6% | 91.7% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.59 | 40.0 | 4.63e-01 | 80.9% | 100.0% |
| 5y6qB02 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.58 | 42.0 | 4.02e-01 | 76.4% | 93.4% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.55 | 38.0 | 3.81e-01 | 71.9% | 85.3% |
| 1li5A02 | 1.20.120.640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.54 | 37.0 | 3.73e-01 | 73.0% | 71.3% |
| 4d3zA02 | 1.10.132.130 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.54 | 48.0 | 4.47e-01 | 100.0% | 80.0% |
| 3di2A00 | 1.20.1250.50 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 37.0 | 3.41e-01 | 71.9% | 76.5% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 36.0 | 3.39e-01 | 70.8% | 80.6% |
| 4fd4A00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 36.0 | 2.83e-01 | 73.0% | 94.8% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 35.0 | 2.78e-01 | 70.8% | 83.3% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 37.0 | 2.70e-01 | 75.3% | 78.4% |
| 7vevA01 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.51 | 45.0 | 3.30e-01 | 100.0% | 99.6% |
| 3au4A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.51 | 35.0 | 2.83e-01 | 85.4% | 33.2% |
| 4wedA02 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.50 | 43.0 | 3.35e-01 | 100.0% | 96.8% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5030154 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.62 | 42.0 | 3.91e-01 | 71.9% | 84.2% |
| 3250261 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.61 | 42.0 | 4.21e-01 | 70.8% | 77.8% |
| 3249096 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.59 | 51.0 | 3.87e-01 | 98.9% | 47.6% |
| 3785339 | 3294.1.1.1 ↗ | alpha complex topology › FAS type I helical domain › FAS type I helical domain › FAS type I helical domain › FAS_I_H | 0.57 | 37.0 | 2.53e-01 | 80.9% | 18.1% |
| 5069344 | 2485.4.1.1 ↗ | a+b three layers › Thioredoxin-like › Fumarate hydratase N-terminal domain › Fumarate hydratase N-terminal domain › Fumerase | 0.56 | 49.0 | 4.00e-01 | 98.9% | 96.5% |
| 3710888 | 4095.1.1.1 ↗ | alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N | 0.55 | 38.0 | 3.39e-01 | 73.0% | 48.5% |
| 3232756 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.55 | 41.0 | 4.17e-01 | 89.9% | 82.4% |
| 4444406 | 3729.1.1.1 ↗ | alpha arrays › Legumain prodomain › Legumain prodomain › Legumain prodomain › Legum_prodom | 0.55 | 47.0 | 4.12e-01 | 97.8% | 64.3% |
| 5078068 | 2485.4.1.1 ↗ | a+b three layers › Thioredoxin-like › Fumarate hydratase N-terminal domain › Fumarate hydratase N-terminal domain › Fumerase | 0.54 | 47.0 | 3.90e-01 | 100.0% | 97.0% |
| 4034192 | 603.1.1.11 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF3169 | 0.53 | 40.0 | 3.13e-01 | 80.9% | 51.5% |
| 4952790 | 2485.4.1.1 ↗ | a+b three layers › Thioredoxin-like › Fumarate hydratase N-terminal domain › Fumarate hydratase N-terminal domain › Fumerase | 0.53 | 46.0 | 3.80e-01 | 100.0% | 100.0% |
| 4948037 | 2485.4.1.1 ↗ | a+b three layers › Thioredoxin-like › Fumarate hydratase N-terminal domain › Fumarate hydratase N-terminal domain › Fumerase | 0.52 | 45.0 | 3.76e-01 | 98.9% | 97.0% |
| 4943686 | 2485.4.1.1 ↗ | a+b three layers › Thioredoxin-like › Fumarate hydratase N-terminal domain › Fumarate hydratase N-terminal domain › Fumerase | 0.52 | 45.0 | 3.80e-01 | 100.0% | 96.9% |
| 4049448 | 185.1.1.1 ↗ | alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl | 0.52 | 42.0 | 4.21e-01 | 97.8% | 86.7% |
| 3886866 | 261.1.1.1 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT | 0.51 | 42.0 | 2.85e-01 | 92.1% | 44.9% |
| 3584854 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 36.0 | 3.31e-01 | 76.4% | 84.8% |
D3
high
residues 1118-1199_1222-1280
D4
medium
residues 1-73
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04997.18 best | RNA_pol_Rpb1_1 | 47.6 | 2.10e-12 | 100.0% | 21.5% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3610049 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.89 | 76.0 | 4.73e-01 | 100.0% | 19.1% |
| 3596097 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.89 | 76.0 | 4.79e-01 | 100.0% | 20.6% |
| 3717545 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.88 | 70.0 | 4.37e-01 | 98.6% | 18.2% |
| 4023558 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.87 | 77.0 | 4.80e-01 | 100.0% | 19.7% |
| 4932731 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.87 | 76.0 | 4.85e-01 | 100.0% | 22.7% |
| 4648965 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.87 | 77.0 | 4.82e-01 | 100.0% | 20.6% |
| 3699234 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.87 | 70.0 | 4.76e-01 | 100.0% | 26.6% |
| 3596876 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.86 | 70.0 | 4.37e-01 | 100.0% | 18.2% |
| 4079870 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.86 | 74.0 | 4.62e-01 | 100.0% | 18.9% |
| 5026630 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.86 | 75.0 | 4.69e-01 | 100.0% | 20.6% |
| 3348138 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 74.0 | 4.60e-01 | 100.0% | 19.4% |
| 3487002 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.85 | 76.0 | 4.74e-01 | 100.0% | 20.0% |
| 4380798 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 74.0 | 4.69e-01 | 100.0% | 20.9% |
| 4877330 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 72.0 | 4.69e-01 | 100.0% | 23.3% |
| 3928969 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 73.0 | 4.41e-01 | 100.0% | 15.6% |
| 3166784 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 75.0 | 4.65e-01 | 100.0% | 18.6% |
| 4871979 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.85 | 74.0 | 5.17e-01 | 100.0% | 32.4% |
| 3737421 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 73.0 | 4.46e-01 | 100.0% | 17.0% |
| 3520695 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.84 | 74.0 | 4.52e-01 | 100.0% | 17.4% |
| 4838956 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.84 | 72.0 | 5.13e-01 | 100.0% | 34.0% |
| 3393665 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.84 | 72.0 | 4.50e-01 | 100.0% | 19.1% |
| 3293738 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 74.0 | 4.57e-01 | 100.0% | 18.4% |
| 4027469 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 72.0 | 4.57e-01 | 100.0% | 20.6% |
| 3482979 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 74.0 | 4.48e-01 | 100.0% | 17.2% |
| 3270404 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 74.0 | 4.49e-01 | 100.0% | 17.0% |
| 3185006 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 74.0 | 4.63e-01 | 100.0% | 20.3% |
| 3479543 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 74.0 | 4.64e-01 | 100.0% | 20.0% |
| 3618547 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 72.0 | 4.35e-01 | 100.0% | 15.9% |
| 3550786 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 72.0 | 4.39e-01 | 100.0% | 16.8% |
| 3409846 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.81 | 72.0 | 4.36e-01 | 100.0% | 16.8% |
| 3205937 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.79 | 69.0 | 4.15e-01 | 100.0% | 15.3% |
| 4069919 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.79 | 72.0 | 4.30e-01 | 100.0% | 15.4% |
| 4826128 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.79 | 69.0 | 6.00e-01 | 100.0% | 64.5% |
| 4809191 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.79 | 69.0 | 4.75e-01 | 100.0% | 30.1% |
| 4001161 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.62 | 53.0 | 3.35e-01 | 100.0% | 18.6% |
D5
medium
residues 74-84_226-280_296-311
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04997.18 best | RNA_pol_Rpb1_1 | 52.1 | 9.40e-14 | 86.6% | 19.9% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 39.0 | 3.68e-01 | 73.2% | 54.1% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.57 | 45.0 | 2.95e-01 | 86.6% | 75.7% |
| 6t0bc01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 37.0 | 3.87e-01 | 72.0% | 73.1% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 39.0 | 3.81e-01 | 73.2% | 69.0% |
| 1lnwF01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 39.0 | 3.42e-01 | 75.6% | 72.6% |
| 1sxjD03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.51 | 37.0 | 3.66e-01 | 87.8% | 71.4% |
ECOD (47)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4380798 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.94 | 90.0 | 5.73e-01 | 100.0% | 66.2% |
| 3293738 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.94 | 90.0 | 5.56e-01 | 100.0% | 70.7% |
| 3409846 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.93 | 89.0 | 5.45e-01 | 100.0% | 75.1% |
| 3928969 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.93 | 89.0 | 5.39e-01 | 100.0% | 74.9% |
| 3618547 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.93 | 89.0 | 5.37e-01 | 100.0% | 74.9% |
| 5026630 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.92 | 88.0 | 5.62e-01 | 100.0% | 64.3% |
| 3737421 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.92 | 88.0 | 5.42e-01 | 100.0% | 73.4% |
| 3550786 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.92 | 87.0 | 5.33e-01 | 100.0% | 73.4% |
| 4889091 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.92 | 87.0 | 5.40e-01 | 100.0% | 58.9% |
| 4001161 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.92 | 87.0 | 5.45e-01 | 100.0% | 69.3% |
| 4932731 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.91 | 87.0 | 5.67e-01 | 100.0% | 63.1% |
| 3610049 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.91 | 87.0 | 5.49e-01 | 100.0% | 67.0% |
| 3596097 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.91 | 87.0 | 5.57e-01 | 100.0% | 65.0% |
| 3482979 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.91 | 86.0 | 5.31e-01 | 100.0% | 70.5% |
| 3270404 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.27e-01 | 100.0% | 75.1% |
| 3293917 | 616.1.1.28 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › RNA_pol_Rpb1_1 | 0.90 | 75.0 | 6.45e-01 | 86.6% | 65.0% |
| 3185006 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.46e-01 | 100.0% | 65.9% |
| 3487002 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.90 | 86.0 | 5.45e-01 | 100.0% | 66.4% |
| 4090024 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.48e-01 | 100.0% | 62.1% |
| 3205937 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.19e-01 | 100.0% | 76.6% |
| 4648965 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.48e-01 | 100.0% | 63.6% |
| 4261674 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.54e-01 | 100.0% | 61.0% |
| 4027469 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 85.0 | 5.46e-01 | 100.0% | 65.5% |
| 3348138 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 86.0 | 5.43e-01 | 100.0% | 66.7% |
| 4634767 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 85.0 | 5.50e-01 | 100.0% | 63.8% |
| 4388548 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.90 | 85.0 | 5.08e-01 | 100.0% | 73.0% |
| 4887352 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.89 | 85.0 | 5.46e-01 | 100.0% | 68.1% |
| 4513601 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.89 | 85.0 | 5.00e-01 | 100.0% | 47.7% |
| 4410658 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.89 | 85.0 | 5.18e-01 | 100.0% | 67.0% |
| 3520695 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.89 | 85.0 | 5.24e-01 | 100.0% | 78.5% |
| 1117727 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.88 | 84.0 | 5.20e-01 | 100.0% | 75.4% |
| 4469646 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.88 | 84.0 | 5.37e-01 | 100.0% | 58.2% |
| 3959944 | 3826.1.1.95 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › RNA_pol_Rpb1_1 | 0.88 | 66.0 | 6.27e-01 | 78.0% | 74.7% |
| 2067927 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.87 | 82.0 | 5.23e-01 | 100.0% | 60.7% |
| 4015766 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.87 | 82.0 | 5.12e-01 | 100.0% | 73.1% |
| 4629506 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.87 | 83.0 | 5.35e-01 | 100.0% | 59.0% |
| 4228406 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.86 | 82.0 | 5.39e-01 | 100.0% | 53.3% |
| 4815139 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.85 | 71.0 | 6.18e-01 | 86.6% | 67.8% |
| 5034821 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.68 | 48.0 | 5.22e-01 | 89.0% | 87.1% |
| 4953007 | 632.11.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DUF357 | 0.63 | 46.0 | 4.81e-01 | 91.5% | 84.0% |
| 4872404 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.62 | 40.0 | 4.39e-01 | 92.7% | 84.4% |
| 4879366 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 48.0 | 3.37e-01 | 90.2% | 62.9% |
| 3911774 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 44.0 | 3.03e-01 | 87.8% | 61.6% |
| 3979729 | 3755.3.1.500 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › IpaC_SipC | 0.55 | 38.0 | 3.31e-01 | 73.2% | 49.2% |
| 4982611 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 37.0 | 3.09e-01 | 72.0% | 47.5% |
| 5000985 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.53 | 40.0 | 3.00e-01 | 79.3% | 36.4% |
| 3496243 | 300.1.1.0 ↗ | a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease | 0.51 | 40.0 | 2.67e-01 | 86.6% | 96.0% |
D6
medium
residues 351-506
Domain cluster:
rep: DNA-directed_RNA_polymerase_subunit_alpha__YP_009238536__Brazilian_marseillevirus__1813599__D353-470
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00623.26 best | RNA_pol_Rpb1_2 | 121.1 | 8.10e-35 | 99.4% | 95.8% |
D7
medium
residues 507-583_646-727
Domain cluster:
rep: DNA-directed_RNA_polymerase_subunit_alpha__YP_009094548__Melbournevirus__1560514__D74-162_215-266
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04983.24 best | RNA_pol_Rpb1_3 | 83.6 | 2.10e-23 | 99.4% | 94.4% |
D8
medium
residues 584-645
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b5iC01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.67 | 31.0 | 2.68e-01 | 83.9% | 27.1% |
| 5aq0B00 | 2.60.40.1120 | Mainly Beta › Sandwich › Immunoglobulin-like › Carboxypeptidase-like, regulatory domain | 0.58 | 36.0 | 3.30e-01 | 75.8% | 47.6% |
| 3au4A02 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.54 | 39.0 | 3.50e-01 | 80.6% | 58.5% |
| 2dymC01 | 3.10.20.620 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.50 | 37.0 | 3.27e-01 | 88.7% | 50.5% |
| 1s55A00 | 2.60.120.40 | Mainly Beta › Sandwich › Jelly Rolls › | 0.50 | 43.0 | 3.19e-01 | 95.2% | 44.9% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3246607 | 11.2.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 | 0.61 | 50.0 | 3.54e-01 | 91.9% | 42.9% |
| 3618543 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.56 | 44.0 | 3.82e-01 | 85.5% | 62.1% |
| 3397821 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.55 | 45.0 | 3.27e-01 | 93.5% | 36.3% |
| 3993281 | 221.1.1.55 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RAWUL | 0.55 | 39.0 | 3.19e-01 | 82.3% | 39.2% |
| 3770607 | 11.1.1.5 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Zona_pellucida | 0.54 | 33.0 | 2.54e-01 | 80.6% | 24.7% |
| 5039010 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.54 | 42.0 | 3.32e-01 | 88.7% | 40.8% |
| 4996063 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.53 | 40.0 | 4.04e-01 | 83.9% | 81.5% |
| 3262846 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.51 | 38.0 | 2.76e-01 | 83.9% | 85.6% |
| 3577849 | 11.1.1.2 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 | 0.50 | 41.0 | 3.55e-01 | 91.9% | 59.0% |
D9
medium
residues 731-877
Domain cluster:
rep: IMGVR_UViG_3300026526_001751-3300026526-Ga0256869_10341511__D627-809
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05000.23 best | RNA_pol_Rpb1_4 | 56.6 | 3.00e-15 | 80.3% | 89.7% |
D10
medium
residues 878-934_1031-1078_1359-1377
D11
medium
residues 1378-1437