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RNA_polymerase_RPO132

Euk-Vir

Mythimna_separata_entomopoxvirus_L

RNA_polymerase_RPO132__YP_008003611__Mythimna_separata_entomopoxvirus_L__1293572

Identity

Accession:: YP_008003611 ↗
Protein ID:: RNA_polymerase_RPO132
Kingdom:: euk

Quality

77.1 mean pLDDT

Cluster

View cluster (5 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 698-801_940-985

PDB

D2 medium residues 24-46_157-168_363-439

PDB

Domain cluster: representative

CATH (14)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4okvE00	6.10.140.1890	Special › Helix non-globular › Helix Hairpins ›	0.68	37.0	4.73e-01	78.6%	92.3%
2fsfB04	1.10.3060.10	Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.65	53.0	4.27e-01	87.5%	78.3%
1nktA04	1.10.3060.10	Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.64	53.0	4.51e-01	87.5%	87.6%
4e6nA02	6.10.140.1010	Special › Helix non-globular › Helix Hairpins ›	0.64	33.0	4.27e-01	72.3%	86.4%
1tjlA00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.63	37.0	3.41e-01	76.8%	45.5%
6xpdA01	1.20.1510.10	Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain	0.60	49.0	4.02e-01	88.4%	63.4%
4o6yB00	1.20.120.1770	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.59	41.0	3.29e-01	71.4%	71.1%
2kg7B00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.58	36.0	3.89e-01	85.7%	73.2%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.56	36.0	4.04e-01	75.0%	82.2%
6jpaE00	1.20.140.150	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 ›	0.55	38.0	3.35e-01	72.3%	84.0%
3zevB00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.54	43.0	3.14e-01	83.9%	64.5%
2c5uA02	1.10.3550.20	Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold ›	0.54	40.0	3.87e-01	78.6%	96.2%
2gbbB00	1.20.59.10	Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase	0.53	40.0	3.67e-01	82.1%	74.2%
5h5mA02	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.53	37.0	3.57e-01	72.3%	93.1%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4932689	4010.1.1.1 ↗	a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1	0.73	66.0	4.90e-01	99.1%	71.6%
4310350	4010.1.1.2 ↗	a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3	0.70	65.0	4.82e-01	100.0%	77.4%
3526151	168.1.1.0 ↗	alpha arrays › Sec7 domain › Sec7 domain › Sec7 domain	0.68	42.0	3.73e-01	98.2%	43.1%
3804219	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.67	43.0	4.80e-01	86.6%	81.1%
3483993	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.64	35.0	3.76e-01	79.5%	60.0%
3240388	5001.1.1.0 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like	0.60	47.0	3.44e-01	83.0%	53.2%
3591561	3881.1.1.1 ↗	alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819	0.58	40.0	3.23e-01	70.5%	47.0%
3284767	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.54	42.0	3.70e-01	82.1%	73.3%
3978828	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.54	41.0	3.66e-01	82.1%	69.1%
3528552	5001.1.1.11 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_4	0.53	47.0	3.41e-01	99.1%	80.9%
3499788	5001.1.1.0 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like	0.52	45.0	3.21e-01	95.5%	54.9%

D3 medium residues 47-156

PDB

Domain cluster: rep: RNA_polymerase_RPO132__YP_008004199__Choristoneura_biennis_entomopoxvirus__10288__D47-126

D4 medium residues 169-362_488-502

PDB

Domain cluster: rep: DNA-directed_RNA_polymerase_subunit_beta__YP_009162498__Salmon_gill_poxvirus__1680908__D173-349

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6ruiB04	3.90.1110.10	Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2	0.79	67.0	7.12e-01	88.5%	100.0%
8himB01	3.90.1110.10	Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2	0.79	56.0	6.55e-01	82.3%	100.0%
7ob9B01	3.90.1110.10	Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2	0.78	68.0	7.10e-01	94.7%	99.5%
3ff0A01	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.55	20.0	2.40e-01	74.2%	47.5%
1vi7A01	3.30.230.30	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › Impact, N-terminal domain	0.54	33.0	3.93e-01	79.4%	91.9%
5ds1A00	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.51	20.0	2.91e-01	84.7%	77.2%
1gesA03	3.30.390.30	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain	0.51	24.0	3.19e-01	77.5%	80.5%

ECOD (28)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2773894	4041.1.1.2 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › rpo132	0.93	81.0	8.64e-01	92.3%	100.0%
4956725	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.80	68.0	7.27e-01	92.3%	100.0%
4980641	4041.1.1.0 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase	0.80	68.0	7.22e-01	94.7%	100.0%
3728986	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.80	66.0	7.11e-01	92.3%	100.0%
3519803	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.78	68.0	7.17e-01	92.8%	100.0%
4979468	4041.1.1.0 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase	0.78	65.0	6.98e-01	93.3%	100.0%
3712713	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.78	68.0	7.14e-01	94.7%	100.0%
3599162	4041.1.1.0 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase	0.78	71.0	6.76e-01	94.7%	100.0%
3626785	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.77	64.0	6.84e-01	92.3%	100.0%
3492371	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.77	67.0	7.00e-01	92.8%	100.0%
4677426	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.76	67.0	6.98e-01	92.3%	100.0%
4902610	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.76	58.0	6.11e-01	82.3%	87.1%
3224052	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.76	66.0	6.93e-01	93.8%	100.0%
3366726	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.75	68.0	6.95e-01	94.7%	100.0%
3517405	375.1.1.0 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related	0.60	22.0	3.80e-01	70.3%	100.0%
4968348	231.1.4.0 ↗	a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Apc (acetophenone carboxylase) beta subunit middle domain	0.58	36.0	4.17e-01	80.9%	83.9%
3458732	243.3.1.19 ↗	a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615	0.54	17.0	3.32e-01	72.2%	100.0%
3600840	330.1.1.0 ↗	a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like	0.54	20.0	2.87e-01	74.6%	68.0%
3879830	216.1.1.0 ↗	a+b two layers › UBC-like › UBC-like › UBC-like	0.54	29.0	3.50e-01	74.2%	75.9%
3384215	330.1.1.0 ↗	a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like	0.53	19.0	3.30e-01	71.8%	97.1%
3746679	216.1.1.4 ↗	a+b two layers › UBC-like › UBC-like › UBC-like › RWD	0.53	29.0	3.61e-01	85.6%	85.6%
3476117	216.1.1.4 ↗	a+b two layers › UBC-like › UBC-like › UBC-like › RWD	0.53	26.0	3.44e-01	75.1%	84.3%
3990414	216.1.1.0 ↗	a+b two layers › UBC-like › UBC-like › UBC-like	0.52	29.0	3.51e-01	75.1%	80.7%
3618875	216.1.1.0 ↗	a+b two layers › UBC-like › UBC-like › UBC-like	0.52	28.0	3.39e-01	75.1%	79.3%
3784499	331.3.1.6 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PRELI	0.51	35.0	3.67e-01	83.3%	75.7%
3472659	216.1.1.0 ↗	a+b two layers › UBC-like › UBC-like › UBC-like	0.51	28.0	3.40e-01	75.1%	78.6%
3820181	216.1.1.4 ↗	a+b two layers › UBC-like › UBC-like › UBC-like › RWD	0.51	27.0	3.34e-01	75.1%	78.5%
4088510	331.3.1.2 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Ring_hydroxyl_A	0.51	34.0	3.13e-01	91.4%	50.4%

D5 medium residues 503-612

PDB

Domain cluster: rep: RNA_polymerase_RPO132__YP_008003891__Adoxophyes_honmai_entomopoxvirus_L__1293540__D506-600

D6 medium residues 613-697

PDB

Domain cluster: rep: DNA-directed_RNA_polymerase_subunit_2__YP_004346997__Lausannevirus__999883__D585-653

D7 medium residues 802-904

PDB

Domain cluster: rep: putative_RNA_polymerase_beta_subunit__YP_009052296__Aureococcus_anophagefferens_virus__1474867__D765-873

CATH (29)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
8igrI01	2.40.270.10	Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6	0.81	76.0	6.23e-01	100.0%	99.4%
2a6hC06	2.40.50.150	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain	0.80	75.0	6.80e-01	100.0%	97.0%
1twfB07	2.40.50.150	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain	0.80	75.0	6.98e-01	100.0%	85.5%
2pmzB07	2.40.50.150	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain	0.79	74.0	6.88e-01	100.0%	85.5%
3d4rB02	2.40.50.100	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain	0.78	51.0	6.14e-01	97.1%	100.0%
1wruA01	2.30.300.10	Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold	0.76	43.0	3.57e-01	98.1%	33.7%
6ruiB07	2.40.50.150	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain	0.73	68.0	6.30e-01	100.0%	85.7%
3kyfA02	2.40.10.220	Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains	0.69	41.0	3.92e-01	100.0%	52.1%
4llfD02	2.60.40.4030	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.66	33.0	3.17e-01	99.0%	40.0%
5eccA00	3.40.430.10	Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A	0.66	32.0	2.75e-01	99.0%	30.6%
3cddA01	2.30.300.10	Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold	0.63	39.0	3.17e-01	99.0%	34.2%
2kcaA00	2.40.10.270	Mainly Beta › Beta Barrel › Thrombin, subunit H › Bacteriophage SPP1 head-tail adaptor protein	0.63	34.0	3.34e-01	100.0%	46.8%
2nwaA01	2.40.240.20	Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › Hypothetical PUA domain-like; domain 1	0.62	34.0	3.86e-01	99.0%	72.0%
2fbjH02	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.61	33.0	3.82e-01	100.0%	72.6%
3gs9A01	6.20.110.10	Special › Other non-globular › Thrombin, subunit H ›	0.61	32.0	3.56e-01	96.1%	62.0%
2apoA03	3.30.70.3190	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.60	36.0	3.80e-01	98.1%	66.3%
2x8kA01	2.40.30.200	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 ›	0.59	40.0	4.04e-01	100.0%	68.6%
2kmwA01	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.57	38.0	3.87e-01	99.0%	68.3%
4ydzA00	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.56	41.0	3.78e-01	100.0%	58.5%
2bolA03	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.56	40.0	4.24e-01	99.0%	83.9%
5ds1A00	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.55	42.0	4.44e-01	97.1%	90.2%
4feiA00	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.54	40.0	4.07e-01	100.0%	79.4%
3f3bA00	2.40.10.370	Mainly Beta › Beta Barrel › Thrombin, subunit H › Protein of unknown function DUF3599	0.52	31.0	3.01e-01	99.0%	51.3%
2p4gA00	3.40.430.10	Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A	0.52	30.0	2.33e-01	99.0%	23.0%
2v9kA04	3.30.70.3190	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.51	34.0	3.43e-01	97.1%	65.1%
2nn5A00	3.30.530.20	Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain	0.51	44.0	3.72e-01	100.0%	57.3%
3c8cB01	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.51	35.0	3.26e-01	100.0%	57.5%
2rdeA02	2.40.10.220	Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains	0.50	32.0	3.14e-01	100.0%	58.6%
1x53A01	3.30.530.20	Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain	0.50	45.0	4.19e-01	100.0%	78.6%

ECOD (68)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2773895	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.89	72.0	7.52e-01	100.0%	92.6%
4932693	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.85	80.0	7.55e-01	100.0%	98.3%
4946076	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.85	80.0	7.41e-01	100.0%	96.8%
4682340	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.85	80.0	7.39e-01	100.0%	96.0%
4976162	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.84	79.0	7.48e-01	100.0%	99.2%
4956728	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.84	79.0	7.24e-01	100.0%	95.4%
3556801	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.84	79.0	7.36e-01	100.0%	95.2%
4970832	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.84	79.0	7.33e-01	100.0%	95.2%
5070341	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.84	79.0	7.30e-01	100.0%	97.6%
5000301	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.83	78.0	7.49e-01	100.0%	100.0%
4323756	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.82	77.0	6.95e-01	100.0%	99.3%
4629505	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.81	76.0	6.76e-01	100.0%	100.0%
4638008	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.80	75.0	7.08e-01	100.0%	95.8%
4513514	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.79	72.0	6.73e-01	98.1%	100.0%
3602252	325.1.7.7 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › DUF2118	0.78	53.0	5.97e-01	100.0%	89.9%
4026621	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.78	74.0	7.08e-01	100.0%	95.7%
4069281	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.78	73.0	6.17e-01	100.0%	96.9%
185291	1.1.13.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Prophage_tailD1	0.77	38.0	4.25e-01	98.1%	60.0%
3491434	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.77	72.0	6.56e-01	99.0%	98.5%
4587173	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.77	72.0	7.24e-01	99.0%	100.0%
3728982	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.77	72.0	6.58e-01	100.0%	93.8%
3610296	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.77	72.0	7.08e-01	100.0%	98.2%
3792089	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.77	72.0	6.47e-01	100.0%	94.8%
3786933	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.76	71.0	6.64e-01	100.0%	96.8%
3302882	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.76	71.0	6.61e-01	100.0%	94.4%
4030042	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.75	70.0	6.37e-01	100.0%	94.7%
4137463	325.1.7.8 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RnfC_N	0.74	50.0	5.63e-01	100.0%	88.7%
4024673	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.73	68.0	6.62e-01	99.0%	100.0%
3412875	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.73	64.0	6.44e-01	100.0%	92.4%
4191050	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.73	68.0	6.52e-01	99.0%	98.3%
3695559	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.71	65.0	6.01e-01	100.0%	94.6%
4883825	1.1.13.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Prophage_tailD1	0.71	41.0	4.34e-01	100.0%	64.1%
4657312	325.1.7.2 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6	0.70	66.0	6.46e-01	100.0%	98.2%
3616946	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.70	64.0	6.38e-01	100.0%	97.1%
3965594	1.1.13.53 ↗	beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Phage-tail_3	0.70	38.0	4.01e-01	100.0%	58.9%
4214150	1.1.5.25 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ	0.69	37.0	3.65e-01	100.0%	50.0%
3267872	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.63	37.0	3.47e-01	100.0%	46.9%
3174542	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.61	50.0	4.63e-01	99.0%	70.0%
3389361	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.61	34.0	3.56e-01	100.0%	57.9%
3937910	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.60	43.0	4.60e-01	98.1%	90.6%
3974181	1.1.5.88 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PF29489	0.59	34.0	3.64e-01	99.0%	63.3%
184986	1.1.13.4 ↗	beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Sipho_tail	0.59	40.0	3.80e-01	100.0%	58.1%
3730893	325.1.7.0 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif	0.59	49.0	5.15e-01	97.1%	98.9%
4602902	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.59	46.0	4.28e-01	100.0%	66.2%
3515632	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.58	43.0	4.09e-01	100.0%	66.7%
3472421	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.58	44.0	4.09e-01	100.0%	63.8%
3782947	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.58	42.0	4.05e-01	100.0%	66.7%
3505751	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.57	42.0	4.26e-01	100.0%	77.1%
3734384	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.57	43.0	4.35e-01	100.0%	79.6%
4936008	1.1.7.28 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › HAS-barrel	0.57	37.0	3.86e-01	100.0%	71.6%
3735669	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.57	41.0	4.20e-01	99.0%	80.4%
3270768	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.56	42.0	4.25e-01	100.0%	78.1%
3513530	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.56	41.0	3.85e-01	100.0%	61.5%
4092054	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.56	44.0	4.22e-01	100.0%	73.9%
3788348	1.1.7.81 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › SEN1_barrel	0.56	39.0	3.82e-01	100.0%	64.3%
3494249	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.55	39.0	3.65e-01	98.1%	57.0%
3627506	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.55	41.0	4.05e-01	100.0%	73.6%
5041132	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.55	42.0	4.04e-01	100.0%	70.6%
4640369	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.55	41.0	4.08e-01	99.0%	78.1%
3652333	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.54	41.0	4.16e-01	100.0%	80.6%
4983910	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.53	42.0	3.93e-01	100.0%	66.9%
3925319	382.1.1.0 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like	0.53	39.0	3.64e-01	93.2%	61.5%
4954283	881.1.1.0 ↗	a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like	0.53	40.0	3.55e-01	99.0%	55.3%
3248540	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.52	38.0	3.82e-01	99.0%	73.6%
4939340	223.8.1.0 ↗	a+b three layers › Profilin-like › LapD periplasmic domain › LapD periplasmic domain	0.52	30.0	3.07e-01	100.0%	54.4%
3821170	319.1.1.15 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › PF27746	0.52	40.0	3.95e-01	98.1%	76.4%
3257721	319.1.1.1 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20	0.52	43.0	4.02e-01	100.0%	73.6%
3256781	319.1.1.0 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones	0.51	44.0	4.30e-01	100.0%	85.8%

D8 medium residues 906-939_1017-1060

PDB

Domain cluster: representative

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1twfB06	2.40.270.10	Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6	0.87	83.0	5.70e-01	100.0%	57.4%
4govA01	2.80.10.50	Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) ›	0.54	37.0	3.19e-01	73.1%	61.1%
2x2sC00	2.80.10.50	Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) ›	0.54	37.0	3.10e-01	73.1%	62.2%
1jlxA01	2.80.10.50	Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) ›	0.53	40.0	3.20e-01	82.1%	62.3%
1jlxA02	2.80.10.50	Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) ›	0.52	37.0	3.17e-01	76.9%	77.1%
1qxmA02	2.80.10.50	Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) ›	0.52	38.0	3.17e-01	79.5%	93.8%
1zxuA00	2.40.160.200	Mainly Beta › Beta Barrel › Porin › LURP1-related	0.51	37.0	2.96e-01	78.2%	69.8%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4896460	1.1.2.32 ↗	beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6, RNA_pol_Rpb2_7	0.84	73.0	5.97e-01	91.0%	94.6%
4896487	1.1.2.1 ↗	beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6	0.84	73.0	5.96e-01	91.0%	94.6%
4636141	1.1.2.1 ↗	beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6	0.84	79.0	5.77e-01	98.7%	76.1%
4148017	1.1.2.1 ↗	beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6	0.83	76.0	5.27e-01	96.2%	80.9%
1839931	6.1.1.0 ↗	beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil	0.51	36.0	3.04e-01	75.6%	91.5%
3177595	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.51	30.0	2.72e-01	80.8%	40.7%
4168024	6.1.1.0 ↗	beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil	0.50	36.0	3.05e-01	76.9%	93.6%

D9 medium residues 1061-1191

PDB

Domain cluster: rep: RNA_polymerase_RPO132__YP_008004199__Choristoneura_biennis_entomopoxvirus__10288__D1075-1173

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF04560.26 best	RNA_pol_Rpb2_7	39.1	1.20e-09	74.8%	93.1%