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RNA_polymerase
Euk-VirCangyuan_orthoreovirus
RNA_polymerase__YP_009110697__Cangyuan_orthoreovirus__1388882
Identity
- Accession:
- YP_009110697 ↗
- Protein ID:
- RNA_polymerase
- Kingdom:
- euk
Quality
89.7
mean pLDDT
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 275-375
Domain cluster:
rep: VP2__YP_009351850__Fall_chinook_aquareovirus__1963254__D281-381
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 90.9 | 6.00e-26 | 100.0% | 8.0% |
D2
medium
residues 38-56_151-190
Domain cluster:
representative
D3
medium
residues 57-150_191-248
Domain cluster:
rep: core_RNA-dependent_RNA_polymerase__YP_009445963__Piscine_orthoreovirus__1157337__D63-154_212-236
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 83.0 | 1.40e-23 | 67.1% | 8.0% |
D4
medium
residues 380-396_454-556_644-684
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 152.9 | 1.10e-44 | 67.1% | 8.1% |
| PF07925.16 | RdRP_5 | 51.8 | 3.60e-14 | 26.7% | 3.2% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.95 | 93.0 | 6.21e-01 | 100.0% | 59.8% |
| 1c0tB01 | 3.10.10.10 | Alpha Beta › Roll › HIV Type 1 Reverse Transcriptase; Chain A, domain 1 › HIV Type 1 Reverse Transcriptase, subunit A, domain 1 | 0.62 | 35.0 | 4.00e-01 | 100.0% | 75.2% |
| 2r7rA05 | 1.10.357.80 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 48.0 | 4.65e-01 | 100.0% | 98.9% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5368 | 304.48.1.23 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_5 | 0.95 | 93.0 | 6.64e-01 | 100.0% | 77.0% |
| 3097450 | 304.48.1.12 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol | 0.63 | 55.0 | 4.14e-01 | 95.7% | 79.0% |
| 3173834 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.59 | 49.0 | 3.64e-01 | 89.4% | 42.4% |
| 3945039 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.59 | 49.0 | 3.87e-01 | 89.4% | 53.0% |
D5
medium
residues 397-453_589-643
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 55.4 | 3.10e-15 | 51.8% | 4.5% |
| PF07925.16 | RdRP_5 | 45.4 | 3.20e-12 | 50.0% | 4.3% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.95 | 92.0 | 5.69e-01 | 100.0% | 48.4% |
| 1x4oA00 | 1.10.10.790 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module | 0.53 | 35.0 | 4.04e-01 | 76.8% | 94.9% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5368 | 304.48.1.23 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_5 | 0.95 | 92.0 | 6.00e-01 | 100.0% | 62.4% |
| 3937960 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.51 | 29.0 | 3.33e-01 | 82.1% | 75.3% |
D6
medium
residues 557-588_685-792
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 142.3 | 1.80e-41 | 77.9% | 8.5% |
| PF07925.16 | RdRP_5 | 42.9 | 1.80e-11 | 24.3% | 2.6% |
CATH (75)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.96 | 94.0 | 6.07e-01 | 100.0% | 46.3% |
| 2r7rA04 | 3.30.70.2480 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.75 | 62.0 | 6.02e-01 | 100.0% | 78.3% |
| 4dezA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.73 | 44.0 | 5.18e-01 | 79.3% | 85.9% |
| 1usmA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.71 | 38.0 | 4.91e-01 | 71.4% | 93.5% |
| 2ebbA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.70 | 40.0 | 4.69e-01 | 71.4% | 80.2% |
| 2kjwA00 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.70 | 43.0 | 5.05e-01 | 78.6% | 89.6% |
| 1khvA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.69 | 59.0 | 6.12e-01 | 92.9% | 97.7% |
| 2ahoB03 | 3.30.70.1130 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha | 0.69 | 43.0 | 5.24e-01 | 72.1% | 100.0% |
| 2la4A00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.68 | 40.0 | 4.58e-01 | 80.7% | 78.2% |
| 1js3A03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.68 | 38.0 | 4.43e-01 | 73.6% | 77.3% |
| 6qwtA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.68 | 61.0 | 6.15e-01 | 100.0% | 95.7% |
| 3n01A00 | 3.30.70.2470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein-tyrosine phosphatase receptor IA-2 ectodomain | 0.68 | 42.0 | 5.10e-01 | 82.9% | 100.0% |
| 4ol8A01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.67 | 50.0 | 5.08e-01 | 98.6% | 80.0% |
| 1dcoA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.67 | 38.0 | 4.40e-01 | 72.1% | 77.8% |
| 2qmaA02 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.67 | 38.0 | 4.06e-01 | 72.9% | 62.4% |
| 1s7hA01 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 38.0 | 4.82e-01 | 83.6% | 98.8% |
| 3trgA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 39.0 | 4.55e-01 | 82.9% | 85.1% |
| 5is2A01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.65 | 42.0 | 5.06e-01 | 79.3% | 98.9% |
| 3p96A02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.65 | 39.0 | 4.86e-01 | 85.0% | 97.6% |
| 3ce8A00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 39.0 | 4.81e-01 | 83.6% | 94.4% |
| 2r4fA03 | 3.30.70.420 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain | 0.65 | 48.0 | 5.19e-01 | 84.3% | 93.2% |
| 1u8sA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 39.0 | 4.82e-01 | 83.6% | 98.8% |
| 2kviA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 35.0 | 4.50e-01 | 82.1% | 97.4% |
| 2d1cA02 | 3.30.70.1570 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 45.0 | 5.04e-01 | 87.1% | 94.6% |
| 2f5gA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.62 | 43.0 | 4.51e-01 | 83.6% | 76.9% |
| 4c8yA01 | 3.30.70.1890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 45.0 | 5.05e-01 | 83.6% | 100.0% |
| 2qpvA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.62 | 43.0 | 4.43e-01 | 70.0% | 99.2% |
| 1r89A03 | 3.30.70.590 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain | 0.62 | 52.0 | 5.34e-01 | 90.7% | 94.0% |
| 2nyiA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.62 | 39.0 | 4.72e-01 | 82.1% | 97.8% |
| 3w3sA01 | 3.30.70.1920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 50.0 | 4.69e-01 | 85.0% | 82.1% |
| 6nqbF00 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.61 | 35.0 | 4.44e-01 | 82.9% | 100.0% |
| 2fyxA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.61 | 47.0 | 4.88e-01 | 80.7% | 87.7% |
| 1q2lA01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.61 | 46.0 | 3.77e-01 | 77.9% | 72.2% |
| 1rkiA01 | 3.30.70.1650 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › PDO, CxxC motif | 0.61 | 41.0 | 4.73e-01 | 82.1% | 97.9% |
| 3dpuB03 | 3.30.310.200 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › | 0.61 | 43.0 | 4.84e-01 | 84.3% | 95.4% |
| 1p1lA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 38.0 | 4.39e-01 | 82.9% | 87.3% |
| 1j2vA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 37.0 | 4.30e-01 | 81.4% | 86.1% |
| 3oq2A00 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 36.0 | 4.19e-01 | 86.4% | 83.8% |
| 7e6gA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.59 | 51.0 | 5.07e-01 | 96.4% | 87.2% |
| 6zxbA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.59 | 52.0 | 5.24e-01 | 96.4% | 92.4% |
| 1iujA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 40.0 | 4.63e-01 | 84.3% | 96.1% |
| 1ry9A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.58 | 37.0 | 3.81e-01 | 72.1% | 66.2% |
| 2ebeA00 | 3.30.70.2290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function (DUF3208) | 0.58 | 41.0 | 4.58e-01 | 75.7% | 95.3% |
| 1p50A02 | 3.30.590.10 | Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain | 0.57 | 46.0 | 3.80e-01 | 86.4% | 75.4% |
| 8c46A01 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 45.0 | 4.91e-01 | 82.1% | 100.0% |
| 1ab8A00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.57 | 50.0 | 4.61e-01 | 93.6% | 80.2% |
| 2d69B01 | 3.30.70.150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain | 0.57 | 43.0 | 4.54e-01 | 90.7% | 87.3% |
| 4pxdA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 44.0 | 4.85e-01 | 82.1% | 99.1% |
| 2c5sA01 | 3.30.2130.30 | Alpha Beta › 2-Layer Sandwich › VC0802-like › | 0.57 | 46.0 | 4.29e-01 | 84.3% | 91.7% |
| 6lpnA03 | 3.30.70.2190 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 43.0 | 4.68e-01 | 80.0% | 96.5% |
| 3n5fA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 44.0 | 4.80e-01 | 82.1% | 99.1% |
| 4xeaA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.57 | 46.0 | 4.15e-01 | 85.7% | 93.8% |
| 4l3tA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.57 | 46.0 | 3.98e-01 | 88.6% | 88.2% |
| 3hdiA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.57 | 46.0 | 4.16e-01 | 87.9% | 91.9% |
| 1t94B02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.56 | 42.0 | 4.50e-01 | 78.6% | 89.9% |
| 6c80A03 | 3.40.462.10 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › FAD-linked oxidases, C-terminal domain | 0.56 | 45.0 | 3.83e-01 | 85.7% | 85.3% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.56 | 43.0 | 4.16e-01 | 83.6% | 93.3% |
| 2fm8B00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.55 | 39.0 | 4.13e-01 | 72.9% | 83.2% |
| 3gb0A02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 42.0 | 4.62e-01 | 82.9% | 99.1% |
| 3zfvA02 | 3.30.70.1900 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 40.0 | 3.92e-01 | 75.7% | 93.6% |
| 2iiiA00 | 3.60.90.10 | Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase | 0.55 | 41.0 | 4.42e-01 | 82.9% | 91.7% |
| 1hr6A01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.55 | 45.0 | 3.91e-01 | 87.1% | 81.8% |
| 3io1A02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 42.0 | 4.53e-01 | 83.6% | 98.3% |
| 7rsfA01 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 42.0 | 4.47e-01 | 81.4% | 100.0% |
| 4cllA01 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.54 | 47.0 | 4.05e-01 | 92.9% | 62.4% |
| 3tvkA00 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.53 | 47.0 | 4.42e-01 | 100.0% | 79.1% |
| 8begA01 | 2.60.40.740 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 40.0 | 3.87e-01 | 83.6% | 68.9% |
| 1rjjA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 38.0 | 4.11e-01 | 85.7% | 92.8% |
| 2p1wA01 | 3.30.2430.10 | Alpha Beta › 2-Layer Sandwich › Phosphothreonine lyase fold › phosphothreonine lyase | 0.52 | 46.0 | 4.27e-01 | 96.4% | 75.7% |
| 3popA02 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.52 | 42.0 | 3.53e-01 | 87.9% | 73.8% |
| 5eufA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.52 | 45.0 | 4.11e-01 | 95.0% | 99.5% |
| 4zmuA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.52 | 45.0 | 4.39e-01 | 95.7% | 85.8% |
| 3rjaA02 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.52 | 42.0 | 3.63e-01 | 88.6% | 81.2% |
| 1r8gA00 | 3.30.590.20 | Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › | 0.51 | 41.0 | 3.09e-01 | 85.0% | 87.5% |
| 2hfsA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.51 | 42.0 | 4.17e-01 | 87.1% | 99.3% |
ECOD (88)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5368 | 304.48.1.23 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_5 | 0.96 | 82.0 | 5.64e-01 | 87.9% | 55.3% |
| 166981 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.70 | 40.0 | 4.69e-01 | 71.4% | 80.2% |
| 3953208 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.70 | 38.0 | 4.51e-01 | 73.6% | 77.7% |
| 4391298 | 304.18.1.1 ↗ | a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS › FDX-ACB | 0.69 | 45.0 | 5.38e-01 | 72.1% | 97.9% |
| 5119 | 304.18.1.1 ↗ | a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS › FDX-ACB | 0.68 | 46.0 | 5.23e-01 | 75.7% | 92.3% |
| 5040671 | 304.8.1.2 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT | 0.67 | 43.0 | 5.27e-01 | 77.9% | 100.0% |
| 3639504 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.67 | 40.0 | 4.43e-01 | 73.6% | 73.6% |
| 3861271 | 304.47.1.0 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain | 0.66 | 46.0 | 5.24e-01 | 72.1% | 95.2% |
| 3591115 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.66 | 46.0 | 5.27e-01 | 83.6% | 99.0% |
| 4980947 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.65 | 42.0 | 5.07e-01 | 85.0% | 100.0% |
| 4377299 | 304.18.1.0 ↗ | a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS | 0.65 | 42.0 | 4.83e-01 | 72.1% | 87.6% |
| 3700778 | 304.159.1.0 ↗ | a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB | 0.65 | 51.0 | 5.53e-01 | 86.4% | 100.0% |
| 3701279 | 304.107.1.10 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › BBS7_pf | 0.65 | 43.0 | 5.21e-01 | 83.6% | 100.0% |
| 4379259 | 304.48.1.6 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A | 0.65 | 48.0 | 5.34e-01 | 82.1% | 99.1% |
| 3941701 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.65 | 45.0 | 5.10e-01 | 84.3% | 95.2% |
| 4588051 | 304.18.1.1 ↗ | a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS › FDX-ACB | 0.64 | 42.0 | 4.76e-01 | 71.4% | 87.5% |
| 3839311 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.64 | 49.0 | 5.40e-01 | 87.1% | 100.0% |
| 3331003 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.64 | 48.0 | 5.37e-01 | 81.4% | 100.0% |
| 5062185 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.64 | 40.0 | 4.78e-01 | 83.6% | 96.7% |
| 3713330 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.64 | 38.0 | 4.06e-01 | 72.1% | 67.5% |
| 3483524 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.63 | 58.0 | 4.45e-01 | 98.6% | 62.0% |
| 4989167 | 304.134.1.0 ↗ | a+b two layers › Alpha-beta plaits › MJ1480-like › MJ1480-like | 0.63 | 42.0 | 4.94e-01 | 82.1% | 97.9% |
| 5000076 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.63 | 46.0 | 5.00e-01 | 75.0% | 100.0% |
| 3495499 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.63 | 57.0 | 4.39e-01 | 98.6% | 60.7% |
| 3414377 | 309.1.1.20 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C, M16C_assoc, PreP_C | 0.62 | 51.0 | 3.10e-01 | 87.9% | 43.6% |
| 193014 | 304.43.1.2 ↗ | a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 › Isocitrate_DH_C_bact | 0.62 | 45.0 | 5.02e-01 | 87.1% | 93.8% |
| 4947808 | 304.25.1.11 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › Peptidase_M20 | 0.62 | 47.0 | 5.20e-01 | 81.4% | 99.1% |
| 3182474 | 309.1.1.16 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, M16C_assoc, PreP_C | 0.62 | 50.0 | 3.05e-01 | 87.9% | 41.1% |
| 5033623 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.62 | 45.0 | 4.14e-01 | 75.7% | 85.4% |
| 4130132 | 309.1.1.24 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, PreP_C | 0.62 | 50.0 | 3.23e-01 | 87.9% | 56.9% |
| 3949691 | 304.28.1.13 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL | 0.62 | 50.0 | 3.39e-01 | 86.4% | 58.8% |
| 3576313 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.62 | 50.0 | 3.71e-01 | 87.9% | 89.3% |
| 3585590 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.62 | 48.0 | 4.10e-01 | 82.9% | 90.9% |
| 3586215 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.61 | 52.0 | 3.27e-01 | 92.9% | 73.1% |
| 4202669 | 304.110.1.4 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › UPF0176_N | 0.61 | 36.0 | 4.23e-01 | 82.9% | 84.2% |
| 3795936 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.61 | 45.0 | 4.26e-01 | 77.1% | 85.9% |
| 4976436 | 884.1.1.0 ↗ | a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain | 0.61 | 43.0 | 4.66e-01 | 73.6% | 99.2% |
| 4930192 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.61 | 51.0 | 4.79e-01 | 91.4% | 95.4% |
| 3260140 | 304.19.1.1 ↗ | a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha | 0.61 | 48.0 | 5.04e-01 | 86.4% | 92.8% |
| 3800111 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.61 | 49.0 | 3.01e-01 | 85.7% | 63.2% |
| 3969826 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.60 | 45.0 | 5.04e-01 | 85.0% | 99.1% |
| 3516671 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.60 | 44.0 | 4.84e-01 | 75.7% | 100.0% |
| 3934377 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.60 | 44.0 | 4.11e-01 | 75.7% | 84.0% |
| 4242666 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.60 | 42.0 | 4.62e-01 | 82.9% | 90.9% |
| 3972846 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.60 | 45.0 | 4.96e-01 | 78.6% | 99.1% |
| 4627986 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.60 | 42.0 | 4.64e-01 | 88.6% | 91.8% |
| 5081921 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.60 | 49.0 | 3.06e-01 | 87.1% | 67.2% |
| 3185641 | 304.25.1.0 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain | 0.60 | 47.0 | 4.92e-01 | 81.4% | 100.0% |
| 4561918 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.60 | 42.0 | 4.69e-01 | 72.9% | 100.0% |
| 3948986 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.60 | 44.0 | 4.93e-01 | 78.6% | 99.1% |
| 4668452 | 304.20.1.0 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0.59 | 46.0 | 5.03e-01 | 92.9% | 100.0% |
| 4063750 | 5067.1.1.26 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL, Sterol-sensing | 0.59 | 48.0 | 3.03e-01 | 86.4% | 65.2% |
| 5009622 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.59 | 44.0 | 4.61e-01 | 75.7% | 96.8% |
| 3798132 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.59 | 46.0 | 3.87e-01 | 82.9% | 90.6% |
| 4221224 | 304.25.1.0 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain | 0.59 | 43.0 | 4.76e-01 | 74.3% | 100.0% |
| 3941700 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.59 | 43.0 | 4.83e-01 | 90.0% | 97.3% |
| 4115602 | 304.48.1.6 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A | 0.59 | 47.0 | 5.07e-01 | 87.9% | 100.0% |
| 3953665 | 304.28.1.13 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL | 0.58 | 40.0 | 4.38e-01 | 73.6% | 85.2% |
| 4107897 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.58 | 43.0 | 4.76e-01 | 90.0% | 97.3% |
| 5074973 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.58 | 45.0 | 4.97e-01 | 82.1% | 100.0% |
| 4928254 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.58 | 46.0 | 4.66e-01 | 83.6% | 93.6% |
| 3290869 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.58 | 46.0 | 4.84e-01 | 82.9% | 98.4% |
| 3990483 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.58 | 42.0 | 3.83e-01 | 75.0% | 86.5% |
| 4258815 | 304.25.1.0 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain | 0.58 | 41.0 | 4.56e-01 | 72.9% | 100.0% |
| 4383381 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.58 | 44.0 | 4.85e-01 | 81.4% | 100.0% |
| 4943141 | 304.25.1.0 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain | 0.58 | 46.0 | 4.90e-01 | 82.9% | 96.7% |
| 3966868 | 304.25.1.0 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain | 0.57 | 45.0 | 4.77e-01 | 82.9% | 98.4% |
| 3954409 | 304.28.1.13 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL | 0.57 | 45.0 | 4.57e-01 | 84.3% | 100.0% |
| 3271910 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.57 | 39.0 | 3.65e-01 | 70.0% | 93.7% |
| 5072924 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.57 | 45.0 | 4.59e-01 | 82.9% | 98.5% |
| 5036027 | 304.1.1.1 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C | 0.56 | 44.0 | 4.56e-01 | 82.9% | 100.0% |
| 4336810 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.56 | 46.0 | 4.88e-01 | 85.7% | 98.4% |
| 3956294 | 3755.3.1.527 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › MMPL | 0.56 | 46.0 | 4.38e-01 | 85.7% | 86.3% |
| 3999103 | 11.1.1.796 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_Shg | 0.56 | 47.0 | 4.54e-01 | 89.3% | 100.0% |
| 3413287 | 11.1.1.796 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_Shg | 0.56 | 46.0 | 4.51e-01 | 89.3% | 98.7% |
| 4248154 | 304.28.1.13 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL | 0.56 | 42.0 | 4.29e-01 | 80.0% | 81.4% |
| 151843 | 304.55.2.0 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like | 0.56 | 43.0 | 4.16e-01 | 83.6% | 93.3% |
| 4997452 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.56 | 43.0 | 4.57e-01 | 82.1% | 99.2% |
| 3036424 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.55 | 43.0 | 4.65e-01 | 82.1% | 99.2% |
| 4342844 | 3223.1.1.1 ↗ | beta sandwiches › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › ASC | 0.55 | 44.0 | 3.13e-01 | 86.4% | 58.1% |
| 4991537 | 304.1.1.1 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C | 0.55 | 44.0 | 4.42e-01 | 84.3% | 95.8% |
| 4946181 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.55 | 44.0 | 4.73e-01 | 86.4% | 99.2% |
| 4997823 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.55 | 43.0 | 4.39e-01 | 82.9% | 98.5% |
| 4534735 | 304.1.1.1 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C | 0.54 | 48.0 | 4.69e-01 | 95.7% | 94.2% |
| 4016257 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.54 | 44.0 | 3.58e-01 | 88.6% | 71.3% |
| 1681577 | 304.48.1.4 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc | 0.54 | 49.0 | 4.57e-01 | 99.3% | 94.2% |
| 4949497 | 304.8.1.111 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › MCR_D | 0.53 | 42.0 | 4.18e-01 | 84.3% | 79.3% |
| 1711357 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.52 | 42.0 | 3.48e-01 | 88.6% | 69.9% |
D7
medium
residues 793-804_819-880
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 70.7 | 7.50e-20 | 100.0% | 6.9% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.97 | 93.0 | 5.40e-01 | 100.0% | 17.3% |
| 4by6D02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 47.0 | 3.40e-01 | 83.8% | 53.8% |
| 1ucrB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 38.0 | 3.87e-01 | 85.1% | 73.3% |
| 1jgsA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 37.0 | 3.10e-01 | 71.6% | 97.1% |
| 3cuqA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 36.0 | 3.55e-01 | 85.1% | 63.7% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 43.0 | 3.00e-01 | 93.2% | 72.5% |
| 1qbjC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 36.0 | 3.80e-01 | 85.1% | 78.8% |
| 1xmkA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 35.0 | 3.51e-01 | 85.1% | 63.3% |
| 2vxzA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 35.0 | 3.63e-01 | 85.1% | 74.2% |
| 2zkzC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 35.0 | 3.39e-01 | 85.1% | 57.5% |
| 6uvuA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 35.0 | 3.21e-01 | 86.5% | 49.0% |
| 3lmmB05 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 35.0 | 3.78e-01 | 86.5% | 85.2% |
| 2obpA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 36.0 | 3.59e-01 | 83.8% | 67.9% |
| 7txnA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 35.0 | 3.36e-01 | 81.1% | 58.9% |
| 3bpvA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 35.0 | 2.93e-01 | 85.1% | 38.7% |
| 2mh2A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 36.0 | 3.87e-01 | 86.5% | 87.5% |
| 2v1nA01 | 1.10.10.2030 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA/RNA-binding protein Kin17, conserved domain | 0.51 | 38.0 | 3.46e-01 | 82.4% | 58.4% |
| 2dk8A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 35.0 | 3.70e-01 | 85.1% | 81.5% |
| 3cuqB03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 34.0 | 3.51e-01 | 86.5% | 73.9% |
| 6j0eB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 35.0 | 3.09e-01 | 85.1% | 45.3% |
| 2d1hB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 34.0 | 3.15e-01 | 86.5% | 52.0% |
| 4a6dA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 35.0 | 3.26e-01 | 87.8% | 56.4% |
| 1r1uB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 33.0 | 3.15e-01 | 87.8% | 54.8% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2389100 | 4967.1.1.10 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_5 | 0.92 | 86.0 | 7.26e-01 | 100.0% | 77.4% |
| 5050717 | 101.1.2.30 ↗ | alpha arrays › HTH › HTH › winged helix domain › TrmB | 0.55 | 36.0 | 3.29e-01 | 85.1% | 48.6% |
| 5039087 | 101.1.2.135 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2 | 0.54 | 36.0 | 3.26e-01 | 85.1% | 48.6% |
| 3582184 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 41.0 | 3.05e-01 | 87.8% | 58.5% |
| 5021499 | 101.1.2.650 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF7343 | 0.54 | 36.0 | 3.46e-01 | 85.1% | 60.0% |
| 5015566 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.54 | 35.0 | 3.42e-01 | 85.1% | 58.8% |
| 5017587 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 35.0 | 3.42e-01 | 86.5% | 60.0% |
| 4980008 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.53 | 35.0 | 3.54e-01 | 86.5% | 66.7% |
| 5042034 | 101.1.2.135 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2 | 0.53 | 35.0 | 3.13e-01 | 85.1% | 45.5% |
| 4982130 | 101.1.2.673 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_HVO_0163_N | 0.53 | 35.0 | 3.50e-01 | 85.1% | 66.7% |
| 3952925 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.53 | 34.0 | 3.26e-01 | 85.1% | 54.4% |
| 4941358 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 34.0 | 3.39e-01 | 85.1% | 61.3% |
| 4961118 | 101.1.2.141 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_24 | 0.53 | 35.0 | 3.31e-01 | 85.1% | 55.6% |
| 5058479 | 101.1.2.650 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF7343 | 0.52 | 35.0 | 3.55e-01 | 85.1% | 69.3% |
| 3700393 | 101.1.2.82 ↗ | alpha arrays › HTH › HTH › winged helix domain › TBPIP | 0.52 | 36.0 | 2.66e-01 | 86.5% | 25.1% |
| 5081804 | 101.1.2.135 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2 | 0.52 | 34.0 | 3.46e-01 | 85.1% | 66.7% |
| 5060133 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 35.0 | 3.35e-01 | 85.1% | 57.8% |
| 5047052 | 101.1.2.673 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_HVO_0163_N | 0.52 | 35.0 | 2.75e-01 | 85.1% | 30.4% |
| 4939406 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 38.0 | 2.96e-01 | 79.7% | 37.1% |
| 5007348 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 38.0 | 3.05e-01 | 85.1% | 38.7% |
| 4946147 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 34.0 | 3.48e-01 | 85.1% | 71.4% |
| 5057802 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.51 | 35.0 | 2.92e-01 | 71.6% | 40.7% |
| 4984339 | 101.1.2.150 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_45 | 0.51 | 35.0 | 3.55e-01 | 87.8% | 70.7% |
| 4980218 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 35.0 | 3.51e-01 | 89.2% | 70.7% |
| 5005001 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 34.0 | 3.09e-01 | 86.5% | 48.6% |
| 5062256 | 101.1.2.673 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_HVO_0163_N | 0.51 | 34.0 | 3.16e-01 | 85.1% | 52.6% |
| 5043670 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.51 | 34.0 | 3.51e-01 | 86.5% | 72.9% |
| 4992848 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 35.0 | 3.05e-01 | 70.3% | 80.0% |
| 5024801 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 33.0 | 2.96e-01 | 85.1% | 42.6% |
| 5049209 | 101.1.2.46 ↗ | alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg | 0.51 | 34.0 | 3.35e-01 | 85.1% | 61.2% |
| 5054374 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 32.0 | 3.61e-01 | 75.7% | 87.0% |
| 4614032 | 101.1.2.92 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_11 | 0.51 | 36.0 | 3.58e-01 | 85.1% | 71.2% |
| 5040253 | 101.1.2.673 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_HVO_0163_N | 0.51 | 33.0 | 3.19e-01 | 85.1% | 55.6% |
| 5069037 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 35.0 | 3.47e-01 | 90.5% | 67.5% |
| 5039360 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.51 | 34.0 | 3.09e-01 | 85.1% | 49.5% |
| 3850850 | 101.1.2.197 ↗ | alpha arrays › HTH › HTH › winged helix domain › APAF-1-like_WHD | 0.51 | 35.0 | 3.41e-01 | 86.5% | 63.5% |
| 5054482 | 101.1.2.141 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_24 | 0.50 | 35.0 | 3.58e-01 | 87.8% | 75.7% |
| 5056461 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.50 | 33.0 | 3.12e-01 | 86.5% | 52.6% |
| 3279731 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.50 | 34.0 | 3.16e-01 | 86.5% | 53.7% |
| 4970461 | 101.1.2.150 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_45 | 0.50 | 34.0 | 3.39e-01 | 85.1% | 68.0% |
| 5020805 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.50 | 33.0 | 3.09e-01 | 86.5% | 51.0% |
| 5035263 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.50 | 34.0 | 3.04e-01 | 86.5% | 48.6% |
| 4998646 | 101.1.2.141 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_24 | 0.50 | 33.0 | 3.15e-01 | 85.1% | 55.6% |
| 5010381 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 35.0 | 3.11e-01 | 86.5% | 49.1% |
| 4998550 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 36.0 | 3.63e-01 | 86.5% | 76.0% |
| 4985757 | 101.1.2.55 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_ScpB | 0.50 | 32.0 | 2.93e-01 | 85.1% | 47.0% |
D8
medium
residues 805-818_928-1040_1127-1159
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07925.16 best | RdRP_5 | 85.8 | 2.10e-24 | 80.0% | 9.5% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 22.0 | 3.10e-01 | 70.6% | 71.6% |
| 4rg8A04 | 1.10.287.1240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 18.0 | 3.00e-01 | 70.6% | 88.7% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1697853 | 4962.1.1.2 ↗ | alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 | 0.91 | 81.0 | 5.89e-01 | 91.3% | 61.0% |
| 2392233 | 4962.1.1.2 ↗ | alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 | 0.88 | 77.0 | 5.64e-01 | 91.3% | 62.9% |
| 5054700 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.53 | 39.0 | 3.28e-01 | 76.9% | 87.6% |
| 4982627 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.53 | 38.0 | 3.23e-01 | 74.4% | 86.2% |