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RNA_polymerase_subunit_1
Euk-VirAfrican_swine_fever_virus
RNA_polymerase_subunit_1__YP_009703361__African_swine_fever_virus__10497
Identity
- Accession:
- YP_009703361 ↗
- Protein ID:
- RNA_polymerase_subunit_1
- Kingdom:
- euk
Quality
71.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Asfuvirales›
Asfarviridae›
Asfivirus›
African_swine_fever_virus
TaxID: 10497
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 88-194
D2
high
residues 538-647
Domain cluster:
rep: putative_DNA_directed_RNA_polymerase_largest_subunit__YP_009052394__Aureococcus_anophagefferens_virus__1474867__D487-612
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04983.24 best | RNA_pol_Rpb1_3 | 68.7 | 8.00e-19 | 99.1% | 56.8% |
D3
high
residues 931-1034
D4
medium
residues 16-83_196-217
Domain cluster:
rep: pig_ID_3158_F95_scaffold_0_curated_closed_complete_prodigal-single.1__X__X__00084__D6-65_144-157
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04997.18 best | RNA_pol_Rpb1_1 | 45.7 | 8.10e-12 | 77.8% | 21.1% |
D5
medium
residues 218-290
D6
medium
residues 314-486
Domain cluster:
rep: LC680885.1__BDE75759.1__X__00221__D247-427
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00623.26 best | RNA_pol_Rpb1_2 | 204.7 | 1.70e-60 | 97.1% | 100.0% |
D7
medium
residues 653-852
Domain cluster:
rep: IMGVR_UViG_3300026526_001751-3300026526-Ga0256869_10341511__D627-809
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05000.23 best | RNA_pol_Rpb1_4 | 56.4 | 3.70e-15 | 54.5% | 92.5% |
| PF04998.23 | RNA_pol_Rpb1_5 | 53.7 | 3.10e-14 | 29.0% | 19.1% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h0gA05 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.90 | 64.0 | 7.51e-01 | 72.5% | 98.6% |
| 5fj8A06 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.87 | 61.0 | 7.11e-01 | 72.0% | 97.3% |
| 5uh5D02 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.85 | 56.0 | 6.78e-01 | 82.0% | 96.4% |
| 4c2mA06 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.82 | 59.0 | 6.48e-01 | 72.5% | 98.8% |
| 2o5iN07 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.78 | 45.0 | 5.93e-01 | 71.5% | 99.1% |
| 2yb5F01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.60 | 26.0 | 3.89e-01 | 71.0% | 93.0% |
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.60 | 24.0 | 3.64e-01 | 72.5% | 88.6% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.57 | 22.0 | 3.40e-01 | 71.5% | 88.2% |
| 8cdaC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.55 | 29.0 | 3.67e-01 | 81.0% | 84.6% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 26.0 | 3.02e-01 | 77.5% | 59.2% |
| 1e7lA02 | 1.10.720.10 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.51 | 17.0 | 2.90e-01 | 70.0% | 98.2% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.50 | 30.0 | 3.72e-01 | 73.0% | 95.8% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4966695 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.92 | 77.0 | 7.49e-01 | 86.0% | 79.5% |
| 5031555 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.91 | 74.0 | 6.32e-01 | 86.0% | 57.2% |
| 4877205 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.90 | 76.0 | 7.48e-01 | 87.0% | 82.3% |
| None | — | 0.90 | 74.0 | 7.28e-01 | 85.5% | 79.9% | |
| 3938779 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.90 | 76.0 | 7.46e-01 | 88.0% | 81.9% |
| 5081035 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.90 | 76.0 | 7.09e-01 | 88.0% | 73.2% |
| 3784119 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.90 | 76.0 | 6.06e-01 | 88.0% | 49.1% |
| 5063898 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.90 | 76.0 | 7.22e-01 | 87.5% | 75.7% |
| 4943462 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.90 | 75.0 | 7.12e-01 | 89.5% | 74.8% |
| 3907707 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.89 | 75.0 | 5.79e-01 | 88.0% | 44.1% |
| 3596868 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.89 | 75.0 | 5.56e-01 | 88.0% | 38.4% |
| 3711496 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.88 | 74.0 | 7.22e-01 | 88.0% | 80.0% |
| 4949113 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.88 | 47.0 | 5.78e-01 | 86.0% | 79.1% |
| 2629809 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.88 | 74.0 | 6.87e-01 | 88.0% | 72.3% |
| 5049548 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.86 | 75.0 | 7.08e-01 | 89.5% | 77.4% |
| 4932735 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.85 | 67.0 | 6.86e-01 | 89.5% | 83.7% |
| 5028612 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.85 | 74.0 | 7.11e-01 | 89.5% | 81.4% |
| 4298800 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.84 | 59.0 | 5.46e-01 | 88.0% | 58.0% |
| 4886353 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.84 | 59.0 | 6.57e-01 | 88.0% | 88.7% |
| 3959563 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.84 | 59.0 | 5.52e-01 | 88.0% | 60.4% |
| 4139172 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.83 | 59.0 | 5.33e-01 | 86.0% | 55.8% |
| 4015744 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.80 | 70.0 | 6.60e-01 | 89.5% | 83.0% |
| 3821041 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.80 | 69.0 | 6.52e-01 | 89.5% | 82.1% |
| 5023529 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.80 | 69.0 | 6.45e-01 | 89.5% | 83.3% |
| 4887358 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.80 | 56.0 | 6.27e-01 | 87.5% | 89.4% |
| 3360995 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.77 | 67.0 | 5.87e-01 | 89.5% | 67.6% |
| 4887310 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.76 | 61.0 | 6.16e-01 | 87.5% | 82.3% |
| 3835577 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.70 | 55.0 | 5.49e-01 | 89.5% | 78.5% |
| 3676029 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.66 | 61.0 | 5.55e-01 | 99.5% | 97.4% |
| 4493491 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.65 | 61.0 | 4.76e-01 | 100.0% | 69.5% |
| 3558280 | 603.1.1.114 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HR1 | 0.52 | 26.0 | 3.71e-01 | 71.0% | 100.0% |
D8
medium
residues 853-930
D9
medium
residues 1120-1260
Domain cluster:
rep: NP1450L__YP_009703155__African_swine_fever_virus__10497__D1120-1260
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04990.18 best | RNA_pol_Rpb1_7 | 30.2 | 5.80e-07 | 90.8% | 78.7% |
D10
medium
residues 1391-1450