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RNA_polymerase_subunit_RP035
Euk-VirTurkeypox_virus
RNA_polymerase_subunit_RP035__YP_009177164__Turkeypox_virus__336486
Identity
- Accession:
- YP_009177164 ↗
- Protein ID:
- RNA_polymerase_subunit_RP035
- Kingdom:
- euk
Quality
89.5
mean pLDDT
Cluster
View cluster (30 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-60
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06015.18 best | Chordopox_A30L | 67.0 | 1.40e-18 | 98.2% | 73.2% |
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.84 | 75.0 | 6.87e-01 | 100.0% | 86.1% |
| 3oo3A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.81 | 58.0 | 3.48e-01 | 76.4% | 12.7% |
| 2nwlC00 | 1.10.3860.10 | Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter | 0.80 | 71.0 | 4.19e-01 | 100.0% | 35.2% |
| 1j2jB00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.79 | 54.0 | 6.03e-01 | 70.9% | 95.1% |
| 2iexA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.70 | 47.0 | 4.88e-01 | 78.2% | 76.5% |
| 2ouwB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.63 | 55.0 | 4.00e-01 | 92.7% | 43.4% |
| 4b94A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 42.0 | 3.17e-01 | 76.4% | 27.0% |
| 7zb5E01 | 3.40.50.10810 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain | 0.60 | 49.0 | 3.01e-01 | 87.3% | 17.9% |
| 4ffbC00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 50.0 | 3.34e-01 | 98.2% | 85.3% |
| 2ndpA00 | 4.10.520.10 | Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins | 0.50 | 40.0 | 3.34e-01 | 89.1% | 53.5% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3891904 | 109.4.1.1608 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro_2, HEAT_MROH2B_1st | 0.83 | 62.0 | 3.66e-01 | 80.0% | 11.9% |
| 3170639 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.82 | 73.0 | 6.34e-01 | 100.0% | 65.9% |
| 3522707 | 109.4.1.1608 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro_2, HEAT_MROH2B_1st | 0.82 | 60.0 | 3.44e-01 | 80.0% | 8.3% |
| 3973453 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.82 | 66.0 | 5.80e-01 | 100.0% | 60.0% |
| 3964469 | 7023.1.1.0 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein | 0.82 | 64.0 | 4.90e-01 | 85.5% | 40.0% |
| 4024303 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.79 | 66.0 | 4.07e-01 | 98.2% | 16.7% |
| 3389690 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.79 | 72.0 | 5.32e-01 | 100.0% | 42.2% |
| 3596592 | 5060.1.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C | 0.77 | 60.0 | 4.81e-01 | 83.6% | 46.7% |
| 3368785 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.77 | 63.0 | 4.87e-01 | 89.1% | 49.6% |
| 3660543 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.76 | 42.0 | 2.96e-01 | 83.6% | 19.4% |
| 4086063 | 309.1.1.4 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C | 0.74 | 53.0 | 3.61e-01 | 76.4% | 22.7% |
| 3503536 | 3711.1.1.38 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Patched | 0.74 | 63.0 | 5.39e-01 | 98.2% | 60.0% |
| 3677530 | 109.4.1.357 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fig4_bd | 0.72 | 58.0 | 3.45e-01 | 89.1% | 43.5% |
D2
high
residues 90-240
Domain cluster:
rep: RNA_polymerase_RPO35__YP_008004474__Choristoneura_rosaceana_entomopoxvirus_L__1293539__D40-183
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03396.22 best | Pox_RNA_pol_35 | 242.6 | 8.20e-72 | 100.0% | 51.7% |
D3
medium
residues 67-89_246-285_345-364
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03396.22 best | Pox_RNA_pol_35 | 45.8 | 7.10e-12 | 77.1% | 20.9% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.66 | 52.0 | 4.49e-01 | 81.9% | 67.5% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.63 | 51.0 | 4.62e-01 | 90.4% | 65.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 53.0 | 4.80e-01 | 100.0% | 93.1% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 51.0 | 4.55e-01 | 92.8% | 67.8% |
| 3tl4X02 | 1.10.10.2420 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.59 | 43.0 | 4.51e-01 | 92.8% | 87.5% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 46.0 | 4.30e-01 | 86.7% | 83.0% |
| 1pq4A01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.55 | 41.0 | 3.38e-01 | 78.3% | 48.0% |
| 3euaA02 | 1.10.10.2240 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.55 | 33.0 | 3.72e-01 | 92.8% | 76.6% |
| 1lqsL01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 46.0 | 4.43e-01 | 100.0% | 92.0% |
| 6zxqA01 | 1.10.300.10 | Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 | 0.52 | 46.0 | 4.45e-01 | 100.0% | 94.6% |
| 3wgtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.50 | 36.0 | 2.76e-01 | 74.7% | 97.5% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3752593 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.69 | 48.0 | 5.40e-01 | 79.5% | 100.0% |
| 3331809 | 375.1.9.23 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › Sterile | 0.69 | 48.0 | 3.75e-01 | 72.3% | 36.0% |
| 54721 | 601.26.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › YppE-like › YppE-like | 0.66 | 52.0 | 4.49e-01 | 81.9% | 67.5% |
| 4124299 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.64 | 53.0 | 5.21e-01 | 90.4% | 91.1% |
| 3180887 | 174.1.1.9 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF1746 | 0.64 | 56.0 | 4.89e-01 | 100.0% | 70.0% |
| 3220580 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.60 | 53.0 | 4.49e-01 | 100.0% | 87.1% |
| 4183685 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.59 | 46.0 | 3.10e-01 | 84.3% | 48.8% |
| 3628698 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 48.0 | 4.26e-01 | 86.7% | 88.7% |
| 3714753 | 2003.1.9.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF | 0.59 | 52.0 | 3.13e-01 | 98.8% | 62.2% |
| 4994613 | 140.1.1.0 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.58 | 44.0 | 3.58e-01 | 80.7% | 80.0% |
| 4948618 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.58 | 48.0 | 3.55e-01 | 95.2% | 36.4% |
| 3601274 | 140.1.1.0 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.58 | 45.0 | 3.32e-01 | 90.4% | 30.0% |
| 4982330 | 3355.1.1.41 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 | 0.57 | 46.0 | 3.01e-01 | 91.6% | 66.3% |
| 4015 | 150.3.1.6 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL10 | 0.55 | 46.0 | 3.93e-01 | 98.8% | 55.6% |
| 4025008 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.54 | 43.0 | 4.13e-01 | 88.0% | 84.2% |
| 4547736 | 604.12.1.111 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27331 | 0.53 | 41.0 | 4.14e-01 | 84.3% | 85.9% |
| 5026592 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.52 | 47.0 | 3.54e-01 | 100.0% | 63.1% |
| 3244409 | 3914.1.1.0 ↗ | alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain | 0.50 | 38.0 | 3.30e-01 | 84.3% | 59.3% |
D4
medium
residues 286-344
Domain cluster:
rep: RNA_polymerase_subunit_RPO35__YP_227503__Deerpox_virus_W-848-83__305674__D227-282
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03396.22 best | Pox_RNA_pol_35 | 59.7 | 4.30e-16 | 100.0% | 20.2% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m6nA00 | 2.20.25.20 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.58 | 34.0 | 3.85e-01 | 89.8% | 76.1% |
| 1a79A02 | 3.40.1170.20 | Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › tRNA intron endonuclease, N-terminal domain | 0.58 | 42.0 | 4.03e-01 | 100.0% | 67.6% |
| 4tkcA00 | 2.90.10.10 | Mainly Beta › Orthogonal Prism › Agglutinin, subunit A › Bulb-type lectin domain | 0.53 | 40.0 | 3.36e-01 | 88.1% | 83.9% |
| 1xf1A05 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 36.0 | 3.11e-01 | 72.9% | 72.3% |
| 3r4cA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.51 | 38.0 | 3.36e-01 | 89.8% | 84.2% |
| 1r75A00 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.50 | 40.0 | 3.36e-01 | 91.5% | 74.5% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5031671 | 242.2.1.2 ↗ | a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N | 0.56 | 42.0 | 4.00e-01 | 98.3% | 68.0% |
| 4645841 | 242.2.1.2 ↗ | a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N | 0.55 | 42.0 | 3.97e-01 | 98.3% | 68.0% |
| 4959202 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.55 | 40.0 | 3.52e-01 | 81.4% | 78.9% |
| 3190335 | 213.1.1.61 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › GNAT_LYC1-like | 0.51 | 37.0 | 2.54e-01 | 83.1% | 36.6% |
| 3172120 | 2004.1.1.250 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd | 0.51 | 38.0 | 2.29e-01 | 79.7% | 73.3% |