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RNA_polymerase_subunit_RP035

Euk-Vir

Turkeypox_virus

RNA_polymerase_subunit_RP035__YP_009177164__Turkeypox_virus__336486

Identity

Accession:
YP_009177164 ↗
Protein ID:
RNA_polymerase_subunit_RP035
Kingdom:
euk

Quality

89.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-60
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06015.18 best Chordopox_A30L 67.0 1.40e-18 98.2% 73.2%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.84 75.0 6.87e-01 100.0% 86.1%
3oo3A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.81 58.0 3.48e-01 76.4% 12.7%
2nwlC00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.80 71.0 4.19e-01 100.0% 35.2%
1j2jB00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.79 54.0 6.03e-01 70.9% 95.1%
2iexA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.70 47.0 4.88e-01 78.2% 76.5%
2ouwB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.63 55.0 4.00e-01 92.7% 43.4%
4b94A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 42.0 3.17e-01 76.4% 27.0%
7zb5E01 3.40.50.10810 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain 0.60 49.0 3.01e-01 87.3% 17.9%
4ffbC00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 50.0 3.34e-01 98.2% 85.3%
2ndpA00 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.50 40.0 3.34e-01 89.1% 53.5%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3891904 109.4.1.1608 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro_2, HEAT_MROH2B_1st 0.83 62.0 3.66e-01 80.0% 11.9%
3170639 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.82 73.0 6.34e-01 100.0% 65.9%
3522707 109.4.1.1608 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro_2, HEAT_MROH2B_1st 0.82 60.0 3.44e-01 80.0% 8.3%
3973453 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.82 66.0 5.80e-01 100.0% 60.0%
3964469 7023.1.1.0 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein 0.82 64.0 4.90e-01 85.5% 40.0%
4024303 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 66.0 4.07e-01 98.2% 16.7%
3389690 174.1.1.29 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 0.79 72.0 5.32e-01 100.0% 42.2%
3596592 5060.1.1.0 alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C 0.77 60.0 4.81e-01 83.6% 46.7%
3368785 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 63.0 4.87e-01 89.1% 49.6%
3660543 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 42.0 2.96e-01 83.6% 19.4%
4086063 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.74 53.0 3.61e-01 76.4% 22.7%
3503536 3711.1.1.38 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Patched 0.74 63.0 5.39e-01 98.2% 60.0%
3677530 109.4.1.357 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fig4_bd 0.72 58.0 3.45e-01 89.1% 43.5%
D2 high residues 90-240
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03396.22 best Pox_RNA_pol_35 242.6 8.20e-72 100.0% 51.7%
D3 medium residues 67-89_246-285_345-364
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03396.22 best Pox_RNA_pol_35 45.8 7.10e-12 77.1% 20.9%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.66 52.0 4.49e-01 81.9% 67.5%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.63 51.0 4.62e-01 90.4% 65.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.61 53.0 4.80e-01 100.0% 93.1%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.60 51.0 4.55e-01 92.8% 67.8%
3tl4X02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.59 43.0 4.51e-01 92.8% 87.5%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 46.0 4.30e-01 86.7% 83.0%
1pq4A01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.55 41.0 3.38e-01 78.3% 48.0%
3euaA02 1.10.10.2240 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.55 33.0 3.72e-01 92.8% 76.6%
1lqsL01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 46.0 4.43e-01 100.0% 92.0%
6zxqA01 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.52 46.0 4.45e-01 100.0% 94.6%
3wgtA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 36.0 2.76e-01 74.7% 97.5%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3752593 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.69 48.0 5.40e-01 79.5% 100.0%
3331809 375.1.9.23 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › Sterile 0.69 48.0 3.75e-01 72.3% 36.0%
54721 601.26.1.0 alpha bundles › Four-helical up-and-down bundle › YppE-like › YppE-like 0.66 52.0 4.49e-01 81.9% 67.5%
4124299 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.64 53.0 5.21e-01 90.4% 91.1%
3180887 174.1.1.9 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF1746 0.64 56.0 4.89e-01 100.0% 70.0%
3220580 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 53.0 4.49e-01 100.0% 87.1%
4183685 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.59 46.0 3.10e-01 84.3% 48.8%
3628698 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 48.0 4.26e-01 86.7% 88.7%
3714753 2003.1.9.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.59 52.0 3.13e-01 98.8% 62.2%
4994613 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.58 44.0 3.58e-01 80.7% 80.0%
4948618 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.58 48.0 3.55e-01 95.2% 36.4%
3601274 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.58 45.0 3.32e-01 90.4% 30.0%
4982330 3355.1.1.41 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 0.57 46.0 3.01e-01 91.6% 66.3%
4015 150.3.1.6 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL10 0.55 46.0 3.93e-01 98.8% 55.6%
4025008 650.1.1.0 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.54 43.0 4.13e-01 88.0% 84.2%
4547736 604.12.1.111 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27331 0.53 41.0 4.14e-01 84.3% 85.9%
5026592 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.52 47.0 3.54e-01 100.0% 63.1%
3244409 3914.1.1.0 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain 0.50 38.0 3.30e-01 84.3% 59.3%
D4 medium residues 286-344
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03396.22 best Pox_RNA_pol_35 59.7 4.30e-16 100.0% 20.2%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2m6nA00 2.20.25.20 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.58 34.0 3.85e-01 89.8% 76.1%
1a79A02 3.40.1170.20 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › tRNA intron endonuclease, N-terminal domain 0.58 42.0 4.03e-01 100.0% 67.6%
4tkcA00 2.90.10.10 Mainly Beta › Orthogonal Prism › Agglutinin, subunit A › Bulb-type lectin domain 0.53 40.0 3.36e-01 88.1% 83.9%
1xf1A05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 36.0 3.11e-01 72.9% 72.3%
3r4cA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.51 38.0 3.36e-01 89.8% 84.2%
1r75A00 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.50 40.0 3.36e-01 91.5% 74.5%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5031671 242.2.1.2 a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.56 42.0 4.00e-01 98.3% 68.0%
4645841 242.2.1.2 a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.55 42.0 3.97e-01 98.3% 68.0%
4959202 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.55 40.0 3.52e-01 81.4% 78.9%
3190335 213.1.1.61 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › GNAT_LYC1-like 0.51 37.0 2.54e-01 83.1% 36.6%
3172120 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.51 38.0 2.29e-01 79.7% 73.3%