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RNA_polymerase_subunit_RPO132

Euk-Vir

Turkeypox_virus

RNA_polymerase_subunit_RPO132__YP_009177160__Turkeypox_virus__336486

Identity

Accession:
YP_009177160 ↗
Protein ID:
RNA_polymerase_subunit_RPO132
Kingdom:
euk

Quality

85.1 mean pLDDT

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 167-338
PDB
Domain cluster: rep: DNA-directed_RNA_polymerase_subunit_beta__YP_009162498__Salmon_gill_poxvirus__1680908__D173-349
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF12415.15 best rpo132 62.5 2.50e-17 18.6% 100.0%
D2 high residues 483-660
PDB
Domain cluster: rep: RNA_polymerase_RPO132__YP_008004199__Choristoneura_biennis_entomopoxvirus__10288__D504-695
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04567.23 best RNA_pol_Rpb2_5 27.3 7.50e-06 27.5% 93.9%
D3 medium residues 16-42_128-166_348-436
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.63 29.0 3.98e-01 77.4% 84.8%
4ikhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 24.0 2.65e-01 70.3% 41.7%
3npiB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 31.0 2.86e-01 75.5% 41.4%
3vkgA11 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.52 32.0 3.79e-01 78.1% 86.4%
3b9wA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.51 40.0 3.11e-01 83.9% 85.4%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4029039 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.82 77.0 5.60e-01 100.0% 82.3%
3492370 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.80 74.0 5.85e-01 98.1% 85.4%
3601611 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.77 73.0 5.57e-01 100.0% 81.5%
3509883 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.76 71.0 5.61e-01 100.0% 82.0%
3605313 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.76 69.0 4.86e-01 98.1% 91.3%
4513137 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.75 71.0 5.40e-01 100.0% 86.6%
5009207 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.75 71.0 5.38e-01 100.0% 85.3%
4932689 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.75 70.0 5.67e-01 98.7% 80.0%
5000297 4010.1.1.0 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.74 69.0 5.34e-01 100.0% 80.9%
4102860 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.71 67.0 5.19e-01 98.7% 79.0%
4241291 4010.1.1.3 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.71 67.0 5.53e-01 98.7% 81.2%
4452307 148.1.1.4 ↗ alpha arrays › Histone-like › Histone-related › Histone › CBFD_NFYB_HMF 0.61 27.0 3.49e-01 88.4% 70.5%
4025692 601.23.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III 0.52 39.0 3.03e-01 77.4% 58.2%
3347927 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.51 43.0 3.53e-01 90.3% 58.9%
3174778 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.50 43.0 3.37e-01 90.3% 48.9%
D4 medium residues 43-127
PDB
Domain cluster: rep: RNA_polymerase_RPO132__YP_008004199__Choristoneura_biennis_entomopoxvirus__10288__D47-126
D5 medium residues 664-732_758-770_861-885_1007-1018
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1twfB06 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.72 69.0 5.40e-01 100.0% 96.4%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3450033 4042.1.1.1 ↗ a+b complex topology › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6 0.92 54.0 5.16e-01 90.8% 53.0%
D6 medium residues 733-757_886-1006
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00562.34 best RNA_pol_Rpb2_6 53.8 2.40e-14 86.3% 28.1%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1twfB06 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.79 76.0 6.42e-01 100.0% 66.8%
1hqmC01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.79 75.0 6.46e-01 100.0% 90.3%
4i8oA03 1.10.8.1130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain 0.62 25.0 3.67e-01 97.3% 80.6%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.53 20.0 2.79e-01 93.8% 68.7%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3582934 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.86 55.0 6.65e-01 77.4% 94.0%
4655578 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.83 80.0 6.67e-01 100.0% 92.6%
4148017 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.83 80.0 6.77e-01 100.0% 92.7%
4026622 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.82 78.0 7.21e-01 100.0% 88.9%
4492078 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.82 78.0 6.35e-01 100.0% 92.8%
4636141 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.81 77.0 7.13e-01 100.0% 90.6%
4039119 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.81 77.0 6.27e-01 100.0% 93.6%
4024674 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.81 78.0 6.53e-01 100.0% 92.9%
4921633 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.81 77.0 6.75e-01 100.0% 93.1%
3613807 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.80 77.0 7.18e-01 100.0% 89.7%
3600872 1.1.2.0 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi 0.80 77.0 7.36e-01 100.0% 92.1%
4946077 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.80 77.0 7.40e-01 100.0% 91.9%
4167437 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.80 76.0 6.76e-01 100.0% 92.3%
4888118 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.79 76.0 7.38e-01 100.0% 91.3%
4902571 1.1.2.32 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6, RNA_pol_Rpb2_7 0.79 76.0 7.37e-01 100.0% 91.3%
4118150 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.78 75.0 7.12e-01 100.0% 90.3%
4665589 131.1.1.4 ↗ alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD,HD_assoc 0.55 44.0 3.29e-01 87.0% 88.5%
3184940 109.4.1.2080 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29875 0.51 38.0 2.87e-01 78.1% 62.8%
4124299 621.1.1.3 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.50 27.0 3.32e-01 96.6% 82.2%
D7 medium residues 771-860
PDB
Domain cluster: rep: putative_RNA_polymerase_beta_subunit__YP_009052296__Aureococcus_anophagefferens_virus__1474867__D765-873
D8 medium residues 1019-1071
PDB
Domain cluster: rep: RNA_polymerase__YP_010085252__Western_grey_kangaroopox_virus__1566307__D1016-1074
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04560.26 best RNA_pol_Rpb2_7 44.2 3.00e-11 58.5% 32.2%
D9 medium residues 1072-1158
PDB
Domain cluster: rep: IMGVR_UViG_3300025836_000142-3300025836-Ga0209748_10097103__D124-188