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RNA_polymerase_subunit_RPO147

Euk-Vir

Penguinpox_virus

RNA_polymerase_subunit_RPO147__YP_009046131__Penguinpox_virus__648998

Identity

Accession:
YP_009046131 ↗
Protein ID:
RNA_polymerase_subunit_RPO147
Kingdom:
euk

Quality

84.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 457-573
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04983.24 best RNA_pol_Rpb1_3 60.8 2.10e-16 100.0% 84.6%
D2 high residues 579-725
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05000.23 best RNA_pol_Rpb1_4 67.3 1.50e-18 74.2% 85.0%
D4 medium residues 13-75_184-246
PDB
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3iqtA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.52 37.0 3.84e-01 76.2% 78.9%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4801458 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.93 90.0 6.66e-01 100.0% 86.1%
5026630 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.86 83.0 5.89e-01 100.0% 81.5%
3166784 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 83.0 5.68e-01 100.0% 82.7%
3185006 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 83.0 5.80e-01 100.0% 82.9%
4648965 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 83.0 5.84e-01 100.0% 80.9%
3487002 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.86 82.0 5.76e-01 100.0% 83.2%
3596876 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.86 82.0 5.76e-01 100.0% 85.3%
4023558 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 82.0 5.74e-01 100.0% 85.5%
4079870 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 82.0 5.70e-01 100.0% 82.5%
4027469 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 82.0 5.81e-01 100.0% 83.0%
4380798 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 82.0 5.83e-01 100.0% 83.7%
3270404 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 81.0 5.49e-01 100.0% 88.9%
4932731 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 82.0 5.98e-01 100.0% 82.0%
3596097 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.85 82.0 5.83e-01 100.0% 82.2%
3717545 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 81.0 5.75e-01 100.0% 86.6%
3393665 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 81.0 5.68e-01 100.0% 85.1%
3610049 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 81.0 5.70e-01 100.0% 82.9%
3293738 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 81.0 5.56e-01 100.0% 85.6%
4069919 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 81.0 5.29e-01 100.0% 88.0%
3348138 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 81.0 5.67e-01 100.0% 82.9%
3618547 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 80.0 5.34e-01 100.0% 87.8%
3482979 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 80.0 5.44e-01 100.0% 84.8%
3479543 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 80.0 5.64e-01 100.0% 84.6%
3737421 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 80.0 5.45e-01 100.0% 87.8%
3550786 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 80.0 5.40e-01 100.0% 87.1%
3928969 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.84 80.0 5.32e-01 100.0% 87.9%
1117727 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.84 79.0 5.42e-01 100.0% 89.5%
4015766 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.84 79.0 5.43e-01 100.0% 87.4%
2150553 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.84 79.0 5.59e-01 100.0% 88.7%
3722540 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.84 79.0 5.36e-01 100.0% 90.4%
3205937 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.83 79.0 5.22e-01 100.0% 93.3%
4877330 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.82 78.0 5.82e-01 100.0% 85.9%
3520695 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.81 77.0 5.25e-01 100.0% 92.8%
3802624 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.77 73.0 5.40e-01 100.0% 85.4%
3778883 604.1.1.168 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › FEZ 0.54 32.0 3.01e-01 88.1% 48.6%
4970833 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.51 29.0 3.76e-01 89.7% 100.0%
D6 medium residues 278-308_370-443
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00623.26 best RNA_pol_Rpb1_2 42.5 1.20e-10 68.6% 39.2%
D7 medium residues 309-369
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2x5cA01 3.30.70.3590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 51.0 4.52e-01 86.9% 86.8%
2e0nB02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.61 51.0 4.32e-01 98.4% 54.5%
4qjvA03 3.30.70.3110 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 39.0 3.95e-01 100.0% 66.1%
1rniA01 3.30.720.160 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Bifunctional DNA primase/polymerase, N-terminal 0.60 46.0 4.45e-01 86.9% 95.7%
1j0hA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.57 43.0 3.98e-01 83.6% 100.0%
2iqcA00 1.25.40.490 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 42.0 3.05e-01 80.3% 42.8%
4kbxA01 2.40.37.30 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › 0.57 46.0 3.29e-01 100.0% 84.3%
3votB02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.56 43.0 2.82e-01 96.7% 17.7%
3p0jA03 1.10.240.10 Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase 0.56 42.0 3.79e-01 86.9% 82.1%
3tiiA03 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.55 44.0 4.35e-01 93.4% 96.9%
1m2gA02 3.30.1600.10 Alpha Beta › 2-Layer Sandwich › SIR2/SIRT2 'Small Domain' › SIR2/SIRT2 'Small Domain' 0.55 42.0 3.74e-01 86.9% 74.2%
3lnnA02 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.54 45.0 4.00e-01 96.7% 100.0%
5z0uA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 3.29e-01 82.0% 69.4%
4izoA02 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.53 43.0 4.25e-01 96.7% 92.5%
6rxpA02 3.30.1600.10 Alpha Beta › 2-Layer Sandwich › SIR2/SIRT2 'Small Domain' › SIR2/SIRT2 'Small Domain' 0.51 40.0 3.57e-01 90.2% 74.7%
2h5eA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 39.0 2.97e-01 88.5% 50.6%
3a21A02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.50 42.0 3.73e-01 95.1% 73.6%
4bfeC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 40.0 3.43e-01 91.8% 90.6%
2zuoA08 2.30.30.620 Mainly Beta › Roll › SH3 type barrels. › 0.50 35.0 3.65e-01 75.4% 94.8%
4durB01 3.50.4.10 Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor 0.50 44.0 4.05e-01 100.0% 95.1%
1yqtA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 36.0 2.50e-01 82.0% 29.7%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4887308 275.1.1.0 a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase 0.96 87.0 8.99e-01 95.1% 100.0%
3659057 275.1.1.0 a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase 0.84 71.0 7.44e-01 96.7% 100.0%
3969863 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.70 48.0 4.63e-01 100.0% 63.2%
4547628 210.2.1.2 a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › SpoIIE 0.62 49.0 3.37e-01 88.5% 92.9%
5003300 1.1.4.0 beta barrels › cradle loop barrel › RIFT-related › Bacterial fluorinating enzyme-C 0.61 52.0 4.76e-01 98.4% 100.0%
4947339 5103.1.1.0 a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 0.60 39.0 3.39e-01 98.4% 40.0%
4249669 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.58 46.0 4.09e-01 90.2% 92.6%
4994964 213.1.1.27 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_7 0.58 44.0 2.94e-01 85.2% 31.6%
4457666 304.22.1.1 a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain › UreE_C 0.58 38.0 3.55e-01 100.0% 52.5%
3240806 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.57 50.0 4.69e-01 100.0% 97.3%
3970513 1.1.7.87 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25954 0.55 46.0 4.21e-01 96.7% 100.0%
3501743 390.1.1.1 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.54 45.0 4.05e-01 98.4% 85.6%
4927074 3325.1.1.1 a+b two layers › UvrB-binding domain of UvrA › UvrB-binding domain of UvrA › UvrB-binding domain of UvrA › UvrA_inter 0.53 44.0 3.64e-01 100.0% 66.4%
3422558 12.1.1.63 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Raffinose_syn 0.53 45.0 3.74e-01 95.1% 67.3%
3615245 109.4.1.621 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_3 0.53 38.0 2.56e-01 80.3% 35.9%
4507638 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.52 42.0 3.14e-01 98.4% 33.3%
3214664 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 44.0 3.71e-01 98.4% 69.1%
4470805 2003.1.4.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.52 42.0 2.90e-01 95.1% 55.6%
3506259 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.52 44.0 3.99e-01 100.0% 88.9%
5047668 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.52 43.0 2.98e-01 100.0% 94.4%
3803208 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.52 45.0 4.18e-01 100.0% 98.8%
3417260 221.1.1.36 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › FERM_N 0.51 41.0 3.74e-01 95.1% 80.0%
3502122 390.1.1.1 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.51 45.0 3.94e-01 98.4% 87.8%
3698595 320.2.1.1 a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain › Ribosomal_S8 0.51 39.0 3.70e-01 100.0% 70.7%
4163860 375.1.1.199 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › MJ0401 0.51 34.0 3.80e-01 93.4% 95.6%
D8 medium residues 726-773_924-956_1229-1252
PDB