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RNA_polymerase_subunit_RPO147

Euk-Vir

Pigeonpox_virus

RNA_polymerase_subunit_RPO147__YP_009046368__Pigeonpox_virus__10264

Identity

Accession:
YP_009046368 ↗
Protein ID:
RNA_polymerase_subunit_RPO147
Kingdom:
euk

Quality

84.1 mean pLDDT

Cluster

View cluster (32 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 997-1095
PDB
Domain cluster: rep: putative_RNA_polymerase_largest_subunit__YP_009001703__Anomala_cuprea_entomopoxvirus__62099__D1033-1131
D2 medium residues 12-76_185-204
PDB
Domain cluster: rep: RNA_polymerase_RPB1_large_subunit__YP_009345156__Noumeavirus__1955558__D1-73
D3 medium residues 77-184
PDB
Domain cluster: rep: DNA-directed_RNA_polymerase_II_largest_subunit__YP_010084808__Shrimp_hemocyte_iridescent_virus__2039780__D81-188
D4 medium residues 205-279
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3dkqA02 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.86 52.0 6.42e-01 82.7% 97.9%
3zgyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.83 49.0 3.96e-01 80.0% 34.9%
3craB01 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.78 53.0 5.07e-01 89.3% 60.5%
1vpdA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.77 45.0 3.68e-01 78.7% 33.6%
2ahmG01 6.10.250.2820 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.76 58.0 5.23e-01 100.0% 60.6%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.74 60.0 5.74e-01 96.0% 76.5%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.73 54.0 5.29e-01 93.3% 71.1%
2jdiG01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.72 53.0 5.79e-01 92.0% 95.1%
1twcA01 4.10.860.120 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › RNA polymerase II, clamp domain 0.69 54.0 4.36e-01 81.3% 61.4%
1z5zA02 1.20.120.850 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain 0.64 40.0 4.03e-01 84.0% 61.8%
3c8zA02 1.20.120.640 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.63 37.0 3.61e-01 77.3% 51.8%
3mekA04 1.25.40.970 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 40.0 4.01e-01 85.3% 61.3%
4ofzA01 1.20.58.1800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 45.0 3.95e-01 94.7% 53.1%
2p6vA00 1.20.120.1110 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › TAFH/NHR1 domain 0.59 46.0 4.22e-01 84.0% 86.6%
2wvxA04 1.20.1610.10 Mainly Alpha › Up-down Bundle › Glycosyl hydrolase family fold › alpha-1,2-mannosidases domains 0.59 47.0 3.57e-01 90.7% 37.6%
3bm1A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.54 39.0 2.94e-01 74.7% 66.7%
2jbrA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.53 41.0 3.60e-01 92.0% 54.6%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4878100 616.1.1.2 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › WHEP-TRS 0.92 51.0 6.82e-01 70.7% 100.0%
5075979 159.1.2.0 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.87 53.0 5.72e-01 80.0% 72.3%
4007623 220.1.1.150 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF986 0.85 54.0 5.08e-01 78.7% 54.4%
5047397 159.1.1.1 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.85 55.0 4.98e-01 84.0% 51.0%
3396277 192.17.1.12 ↗ alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › WHEP-TRS 0.85 57.0 6.38e-01 84.0% 86.7%
5041347 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.83 54.0 3.76e-01 82.7% 23.3%
3175298 130.1.1.51 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Tho1_MOS11_C 0.83 48.0 5.37e-01 72.0% 73.3%
3640243 605.4.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.81 56.0 5.67e-01 88.0% 72.0%
3867542 3826.1.1.0 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.80 57.0 5.42e-01 89.3% 64.7%
3565896 3860.1.1.130 ↗ alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › Yae1_N 0.80 57.0 4.66e-01 89.3% 43.1%
162110 616.1.1.2 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › WHEP-TRS 0.79 52.0 5.19e-01 84.0% 64.6%
1487360 3929.1.1.1 ↗ alpha bundles › THO1 C-terminal domain › THO1 C-terminal domain › THO1 C-terminal domain › Tho1_MOS11_C 0.79 47.0 4.96e-01 70.7% 67.2%
4801458 4246.1.1.2 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.79 69.0 4.52e-01 92.0% 84.3%
3204106 605.4.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.79 53.0 5.21e-01 82.7% 65.0%
2546344 3826.1.1.1 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Trns_repr_metal 0.79 58.0 6.34e-01 94.7% 96.7%
3660125 3711.1.1.4 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 0.76 61.0 5.84e-01 96.0% 74.1%
3928969 4246.1.1.2 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.73 66.0 4.03e-01 98.7% 83.7%
3293917 616.1.1.28 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › RNA_pol_Rpb1_1 0.73 59.0 4.90e-01 84.0% 55.0%
4023943 4246.1.1.2 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.73 67.0 4.29e-01 98.7% 71.7%
4001161 4246.1.1.2 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.71 66.0 4.13e-01 100.0% 26.3%
3721864 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.71 50.0 5.30e-01 96.0% 84.6%
3293738 4246.1.1.2 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.71 66.0 4.09e-01 100.0% 23.7%
4452814 140.1.1.7 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.70 49.0 4.02e-01 86.7% 40.7%
3676620 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.69 65.0 3.95e-01 100.0% 40.7%
3326008 5086.1.1.96 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF632 0.66 61.0 5.50e-01 100.0% 89.0%
3200945 140.1.1.0 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.66 45.0 3.68e-01 85.3% 37.9%
3649362 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.66 60.0 3.78e-01 100.0% 38.1%
3390311 604.7.1.0 ↗ alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.65 56.0 4.92e-01 93.3% 77.3%
4285886 140.1.1.4 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.64 55.0 4.21e-01 93.3% 82.5%
D5 medium residues 301-371
PDB
Domain cluster: rep: RNA_polymerase_subunit_RPO147__YP_009046131__Penguinpox_virus__648998__D309-369
D6 medium residues 459-512_544-573
PDB
Domain cluster: rep: RNA_polymerase__YP_010085368__Eastern_grey_kangaroopox_virus__2042482__D459-574
D7 medium residues 615-752
PDB
Domain cluster: rep: DNA-directed_RNA_polymerase_147_kDa_polypeptide__YP_009329703__BeAn_58058_virus__67082__D598-725
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05000.23 best RNA_pol_Rpb1_4 67.8 9.90e-19 72.5% 84.1%
D8 medium residues 957-979_1141-1205
PDB
Domain cluster: rep: RNA_polymerase_subunit__YP_009177121__Turkeypox_virus__336486__D959-979_1149-1201