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RNA_polymerase_subunit_RPO147_protein
Euk-VirRaccoonpox_virus
RNA_polymerase_subunit_RPO147_protein__YP_009143406__Raccoonpox_virus__10256
Identity
- Accession:
- YP_009143406 ↗
- Protein ID:
- RNA_polymerase_subunit_RPO147_protein
- Kingdom:
- euk
Quality
83.4
mean pLDDT
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 460-572
Domain cluster:
rep: RNA_polymerase__YP_010085368__Eastern_grey_kangaroopox_virus__2042482__D459-574
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04983.24 best | RNA_pol_Rpb1_3 | 33.8 | 4.20e-08 | 100.0% | 84.0% |
D2
high
residues 995-1095
D3
medium
residues 13-70_190-235
D4
medium
residues 71-189
D5
medium
residues 285-443
Domain cluster:
rep: LC680885.1__BDE75759.1__X__00221__D247-427
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00623.26 best | RNA_pol_Rpb1_2 | 93.5 | 2.40e-26 | 98.1% | 95.2% |
D6
medium
residues 581-744
Domain cluster:
rep: DNA-directed_RNA_polymerase_147_kDa_polypeptide__YP_009329703__BeAn_58058_virus__67082__D598-725
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05000.23 best | RNA_pol_Rpb1_4 | 62.7 | 3.80e-17 | 66.5% | 85.0% |
D7
medium
residues 745-789_918-958_1229-1252
Domain cluster:
rep: RNA_polymerase_subunit__YP_009177121__Turkeypox_virus__336486__D729-783_925-958
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04998.23 best | RNA_pol_Rpb1_5 | 43.3 | 4.60e-11 | 93.6% | 29.6% |
D8
medium
residues 790-845
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8a0cA01 | 3.40.50.11820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CDP-glycerol glycerophosphotransferase, N-terminal domain | 0.52 | 42.0 | 3.10e-01 | 92.9% | 96.9% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4887311 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 0.98 | 85.0 | 6.24e-01 | 100.0% | 40.5% |
| 4267176 | 2004.1.1.442 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 | 0.53 | 41.0 | 2.62e-01 | 91.1% | 85.1% |
| 4276439 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.51 | 38.0 | 2.44e-01 | 89.3% | 80.0% |
D9
medium
residues 846-917
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vbiA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.65 | 48.0 | 4.28e-01 | 87.5% | 55.3% |
| 1vhnA02 | 1.10.1200.80 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 | 0.64 | 43.0 | 4.38e-01 | 91.7% | 71.8% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.62 | 48.0 | 4.68e-01 | 84.7% | 74.1% |
| 1yfmA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.62 | 53.0 | 4.53e-01 | 100.0% | 81.7% |
| 4nk2A01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 53.0 | 4.28e-01 | 98.6% | 83.6% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 41.0 | 3.66e-01 | 72.2% | 72.7% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.59 | 46.0 | 4.35e-01 | 86.1% | 80.7% |
| 1kblA05 | 1.20.80.30 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.59 | 46.0 | 4.35e-01 | 87.5% | 75.3% |
| 6xm1A02 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.59 | 40.0 | 3.52e-01 | 72.2% | 57.5% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.59 | 48.0 | 4.33e-01 | 94.4% | 79.0% |
| 2ra1A02 | 1.20.58.780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 39.0 | 4.07e-01 | 70.8% | 86.8% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.58 | 47.0 | 4.48e-01 | 94.4% | 92.0% |
| 5iwuA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.57 | 48.0 | 3.62e-01 | 98.6% | 82.0% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 38.0 | 3.72e-01 | 72.2% | 69.2% |
| 2x1dA02 | 1.10.10.2120 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.53 | 41.0 | 4.12e-01 | 87.5% | 82.4% |
| 4jb3A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.53 | 35.0 | 3.57e-01 | 70.8% | 69.4% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.52 | 35.0 | 3.82e-01 | 70.8% | 94.6% |
| 2wgoA00 | 3.10.450.260 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 41.0 | 3.73e-01 | 88.9% | 84.7% |
| 3nbiA01 | 1.10.8.1020 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain | 0.51 | 36.0 | 3.91e-01 | 80.6% | 96.6% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4887311 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 1.00 | 94.0 | 7.47e-01 | 100.0% | 55.6% |
| 3365302 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 57.0 | 3.88e-01 | 91.7% | 77.9% |
| 4964983 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.70 | 47.0 | 4.41e-01 | 70.8% | 65.6% |
| 4965039 | 2488.1.1.1 ↗ | a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase | 0.67 | 56.0 | 3.91e-01 | 94.4% | 27.3% |
| 3290543 | 150.5.1.11 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › T7SS_ESX_EspC | 0.66 | 45.0 | 3.96e-01 | 70.8% | 47.2% |
| 3247035 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.63 | 55.0 | 3.64e-01 | 100.0% | 43.3% |
| 3200003 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 44.0 | 3.82e-01 | 75.0% | 83.5% |
| 4192675 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.60 | 50.0 | 4.63e-01 | 94.4% | 82.1% |
| 4144086 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.60 | 45.0 | 4.17e-01 | 83.3% | 68.0% |
| 4025800 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.60 | 48.0 | 4.43e-01 | 88.9% | 80.0% |
| 4478129 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.60 | 46.0 | 4.34e-01 | 84.7% | 74.4% |
| 5069176 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.60 | 47.0 | 4.78e-01 | 88.9% | 92.9% |
| 3575609 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.59 | 44.0 | 4.62e-01 | 83.3% | 96.9% |
| 3703593 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.58 | 47.0 | 3.60e-01 | 91.7% | 42.2% |
| 4943264 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.58 | 48.0 | 4.77e-01 | 94.4% | 98.7% |
| 4995204 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 47.0 | 4.75e-01 | 94.4% | 98.6% |
| 5014266 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 48.0 | 4.76e-01 | 95.8% | 94.7% |
| 3927235 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.57 | 46.0 | 4.70e-01 | 91.7% | 95.7% |
| 3288893 | 604.1.1.141 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF349 | 0.57 | 39.0 | 3.85e-01 | 75.0% | 65.0% |
| 3404085 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.56 | 38.0 | 3.83e-01 | 70.8% | 90.7% |
| 3924999 | 3687.1.1.1 ↗ | alpha bundles › NADPH-cytochrome p450 reductase helical insertion domain › NADPH-cytochrome p450 reductase helical insertion domain › NADPH-cytochrome p450 reductase helical insertion domain › FAD_binding_1 | 0.56 | 43.0 | 3.50e-01 | 86.1% | 44.4% |
| 1871752 | 864.1.1.2 ↗ | a+b two layers › DLC › DLC › DLC › Tctex-1 | 0.55 | 39.0 | 3.34e-01 | 75.0% | 61.7% |
| 3335320 | 5054.1.1.1 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan | 0.54 | 40.0 | 3.80e-01 | 97.2% | 64.4% |
| 3988260 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.53 | 35.0 | 2.38e-01 | 70.8% | 15.4% |
| 3599088 | 864.1.1.0 ↗ | a+b two layers › DLC › DLC › DLC | 0.52 | 41.0 | 3.50e-01 | 86.1% | 65.3% |
| 3901917 | 1134.1.1.7 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 | 0.50 | 41.0 | 4.22e-01 | 88.9% | 91.4% |