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RNA_polymerase_subunit_RPO35
Euk-VirDeerpox_virus_W-848-83
RNA_polymerase_subunit_RPO35__YP_227503__Deerpox_virus_W-848-83__305674
Identity
- Accession:
- YP_227503 ↗
- Protein ID:
- RNA_polymerase_subunit_RPO35
- Kingdom:
- euk
Quality
93.3
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Cervidpoxvirus›
Deerpox_virus_W-848-83
TaxID: 305674
Cluster
View cluster (30 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 30-180
Domain cluster:
rep: RNA_polymerase_RPO35__YP_008004474__Choristoneura_rosaceana_entomopoxvirus_L__1293539__D40-183
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03396.22 best | Pox_RNA_pol_35 | 252.0 | 1.10e-74 | 100.0% | 51.0% |
D2
high
residues 227-282
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03396.22 best | Pox_RNA_pol_35 | 78.1 | 1.10e-21 | 100.0% | 19.5% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1r75A00 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.60 | 47.0 | 3.84e-01 | 87.5% | 88.2% |
| 4p55B00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 40.0 | 3.56e-01 | 92.9% | 97.9% |
| 3nwnA00 | 3.40.850.10 | Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain | 0.51 | 41.0 | 2.67e-01 | 96.4% | 42.5% |
D3
medium
residues 191-226_283-300
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03396.22 best | Pox_RNA_pol_35 | 45.3 | 1.00e-11 | 94.4% | 14.4% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.87 | 65.0 | 5.71e-01 | 81.5% | 56.8% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.82 | 56.0 | 4.43e-01 | 72.2% | 57.8% |
| 6ldkA01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.81 | 60.0 | 4.13e-01 | 77.8% | 26.7% |
| 2l35A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.74 | 55.0 | 5.25e-01 | 81.5% | 74.6% |
| 3eo8A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.73 | 58.0 | 3.87e-01 | 88.9% | 23.3% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.72 | 61.0 | 4.81e-01 | 100.0% | 55.4% |
| 4nrjB01 | 3.90.20.10 | Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B › | 0.72 | 51.0 | 3.68e-01 | 77.8% | 48.4% |
| 5u1xA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.70 | 47.0 | 4.94e-01 | 70.4% | 93.5% |
| 1kf6D00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.69 | 56.0 | 4.37e-01 | 90.7% | 57.1% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.68 | 52.0 | 3.73e-01 | 87.0% | 85.2% |
| 1om2A00 | 1.20.960.10 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › Mitochondrial outer membrane translocase complex, subunit Tom20 domain | 0.67 | 50.0 | 4.23e-01 | 90.7% | 46.3% |
| 1xfiA02 | 1.20.1700.10 | Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like | 0.67 | 50.0 | 4.35e-01 | 85.2% | 66.7% |
| 3besR03 | 6.10.140.1480 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 49.0 | 4.94e-01 | 88.9% | 78.6% |
| 4hb1A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.67 | 46.0 | 4.96e-01 | 72.2% | 90.9% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.66 | 49.0 | 4.73e-01 | 83.3% | 70.3% |
| 3ilxA02 | 1.10.287.2170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 48.0 | 5.27e-01 | 83.3% | 95.5% |
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 49.0 | 4.74e-01 | 81.5% | 77.4% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.65 | 53.0 | 3.93e-01 | 96.3% | 51.6% |
| 4lqqB00 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.65 | 51.0 | 3.77e-01 | 87.0% | 43.8% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 47.0 | 4.29e-01 | 75.9% | 69.0% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 54.0 | 4.72e-01 | 92.6% | 91.4% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.64 | 53.0 | 4.03e-01 | 94.4% | 45.9% |
| 3dkqA02 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.63 | 46.0 | 4.86e-01 | 77.8% | 89.4% |
| 4gm2A00 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.62 | 51.0 | 3.52e-01 | 90.7% | 27.3% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.62 | 52.0 | 4.84e-01 | 100.0% | 78.9% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 45.0 | 4.31e-01 | 88.9% | 67.7% |
| 4r60A01 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.59 | 45.0 | 3.22e-01 | 83.3% | 50.6% |
| 2damA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.58 | 34.0 | 3.17e-01 | 77.8% | 47.8% |
| 2dzlA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.58 | 40.0 | 3.78e-01 | 79.6% | 59.1% |
| 5mmjb02 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.57 | 42.0 | 4.33e-01 | 98.1% | 82.7% |
| 3gr3A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.57 | 50.0 | 3.30e-01 | 100.0% | 58.0% |
| 2gmsB01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.57 | 48.0 | 3.17e-01 | 100.0% | 92.1% |
| 3deeA01 | 1.10.150.690 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 | 0.56 | 47.0 | 4.11e-01 | 96.3% | 80.2% |
| 1z7mC00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 46.0 | 2.95e-01 | 100.0% | 55.3% |
| 2jbrA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 43.0 | 3.48e-01 | 100.0% | 63.0% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5052262 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.82 | 67.0 | 5.95e-01 | 88.9% | 78.7% |
| 4940116 | 140.1.1.14 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e | 0.80 | 58.0 | 4.20e-01 | 77.8% | 30.3% |
| 5049807 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.78 | 60.0 | 5.61e-01 | 81.5% | 67.7% |
| 5070479 | 304.1.1.0 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain | 0.74 | 52.0 | 4.01e-01 | 74.1% | 33.3% |
| 3282145 | 618.2.1.1 ↗ | a+b complex topology › DNA mimic protein DMP12-like › Immunity protein CdiI › Immunity protein CdiI › DUF6247 | 0.73 | 48.0 | 4.86e-01 | 75.9% | 67.3% |
| 4947051 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.73 | 53.0 | 3.43e-01 | 77.8% | 20.0% |
| 5082509 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.71 | 58.0 | 4.41e-01 | 90.7% | 89.2% |
| 4077305 | 5069.1.3.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_D | 0.70 | 54.0 | 4.15e-01 | 85.2% | 61.6% |
| 3718969 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.70 | 53.0 | 3.75e-01 | 83.3% | 25.7% |
| 4971062 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.70 | 53.0 | 4.57e-01 | 81.5% | 69.4% |
| 4000005 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.69 | 53.0 | 4.83e-01 | 81.5% | 71.4% |
| 4213809 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 51.0 | 4.73e-01 | 81.5% | 65.7% |
| 5037588 | 253.1.1.1 ↗ | a+b complex topology › Argininosuccinate synthetase-C › Argininosuccinate synthetase-C › Argininosuccinate synthetase-C › Arginosuc_syn_C | 0.68 | 47.0 | 3.26e-01 | 75.9% | 21.7% |
| 5035319 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 51.0 | 4.92e-01 | 81.5% | 71.7% |
| 4186632 | 4146.1.1.3 ↗ | alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like › PKHD_C | 0.68 | 49.0 | 5.25e-01 | 77.8% | 91.1% |
| 3175611 | 3755.3.1.361 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › MIS13 | 0.67 | 52.0 | 4.79e-01 | 83.3% | 74.3% |
| 3285148 | 3730.1.1.5 ↗ | alpha arrays › CCM3/GCKIII dimerization domain › CCM3/GCKIII dimerization domain › CCM3/GCKIII dimerization domain › DUF6247 | 0.64 | 44.0 | 4.39e-01 | 72.2% | 70.9% |
| 4614833 | 102.1.1.83 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SHLD1_C | 0.63 | 46.0 | 4.02e-01 | 77.8% | 52.5% |
| 4674043 | 632.11.1.12 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › UVR | 0.63 | 48.0 | 4.08e-01 | 81.5% | 50.0% |
| None | — | 0.62 | 53.0 | 3.25e-01 | 100.0% | 77.6% | |
| 3381592 | 2486.1.1.6 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ACCA | 0.62 | 48.0 | 2.91e-01 | 79.6% | 82.1% |
| 4419635 | 5069.1.3.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_D | 0.61 | 45.0 | 3.73e-01 | 87.0% | 50.9% |
| 4007623 | 220.1.1.150 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF986 | 0.61 | 51.0 | 4.45e-01 | 100.0% | 84.4% |
| 3592841 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.60 | 44.0 | 4.03e-01 | 75.9% | 58.6% |
| 3818350 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.58 | 50.0 | 3.25e-01 | 100.0% | 61.5% |
| 3329960 | 109.4.1.1286 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 | 0.57 | 48.0 | 3.04e-01 | 98.1% | 30.1% |
| 4987553 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.56 | 45.0 | 3.67e-01 | 100.0% | 47.2% |
| 3683524 | 109.4.1.1261 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long | 0.55 | 47.0 | 3.32e-01 | 100.0% | 28.9% |
| 4286656 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.54 | 44.0 | 3.70e-01 | 100.0% | 73.6% |
| 4095142 | 109.4.1.465 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SPO22 | 0.54 | 42.0 | 3.28e-01 | 96.3% | 36.8% |
| 3429553 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.54 | 39.0 | 3.10e-01 | 96.3% | 35.2% |