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RNaseIII

Euk-Vir

Heliothis_virescens_ascovirus_3f

RNaseIII__YP_009701491__Heliothis_virescens_ascovirus_3f__328614

Identity

Accession:
YP_009701491 ↗
Protein ID:
RNaseIII
Kingdom:
euk

Quality

64.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Ascoviridae› Ascovirus› Heliothis_virescens_ascovirus_3f

TaxID: 328614

Cluster

View cluster (4 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 374-442
PDB
Domain cluster: representative
CATH (68)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3c4bA02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.80 69.0 6.99e-01 97.1% 94.0%
1whqA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.79 69.0 6.89e-01 95.7% 100.0%
7r97A02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.79 67.0 6.78e-01 92.8% 100.0%
2nugB02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.78 68.0 6.75e-01 95.7% 95.8%
3rv0B03 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.77 69.0 6.62e-01 100.0% 93.7%
1bu6O01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.77 57.0 3.79e-01 78.3% 28.3%
2dmyA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.75 64.0 5.67e-01 100.0% 66.0%
2l33A00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.75 63.0 5.76e-01 100.0% 70.3%
3zeuB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.73 53.0 3.86e-01 75.4% 41.9%
1t4lB00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.73 65.0 6.01e-01 100.0% 84.4%
1uhzA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.73 66.0 6.03e-01 100.0% 77.5%
3tqmA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.73 65.0 5.95e-01 97.1% 77.8%
1imuA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.72 64.0 5.46e-01 95.7% 65.4%
2ywqA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.71 65.0 5.90e-01 98.6% 78.4%
1c9rA04 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.70 53.0 4.64e-01 82.6% 61.7%
2k49A00 2.30.29.80 Mainly Beta › Roll › PH-domain like › 0.69 52.0 4.39e-01 81.2% 86.4%
2ch5A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.69 58.0 4.49e-01 89.9% 46.5%
2a5zA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.69 47.0 3.24e-01 72.5% 27.6%
1sr9A02 3.30.160.270 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Alpha-isopropylmalate synthase LeuA, regulatory domain 0.68 59.0 4.35e-01 92.8% 66.5%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.67 56.0 5.42e-01 94.2% 86.1%
3f6gA01 3.30.160.740 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.67 52.0 5.57e-01 85.5% 100.0%
4eo3A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.65 45.0 3.65e-01 73.9% 84.1%
3brcA02 3.40.50.10150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › B12-dependent dehydatase associated subunit 0.63 53.0 4.55e-01 98.6% 87.5%
1wzvA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.63 52.0 4.13e-01 94.2% 67.3%
2b5iC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 44.0 3.95e-01 73.9% 96.9%
1ylxA00 3.30.70.1480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GK1464-like 0.62 51.0 4.60e-01 94.2% 84.8%
7ahfA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.62 50.0 4.01e-01 92.8% 67.8%
2d73A01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.61 51.0 3.37e-01 92.8% 98.2%
3htvA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 45.0 3.92e-01 81.2% 54.1%
1x23B00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.60 49.0 3.88e-01 92.8% 65.1%
1g5hA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.60 52.0 3.48e-01 100.0% 81.7%
2h2yA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.60 48.0 4.19e-01 94.2% 87.1%
3drnB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.59 49.0 3.92e-01 95.7% 66.7%
2f4wB00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.59 50.0 3.94e-01 97.1% 67.1%
3lodA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.59 45.0 3.53e-01 82.6% 55.9%
3ewaA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 42.0 2.87e-01 75.4% 94.4%
1okjA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.58 41.0 3.71e-01 79.7% 54.7%
5epfA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.58 47.0 3.75e-01 95.7% 65.6%
5ic7A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.57 47.0 3.02e-01 92.8% 29.1%
3gkmA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.57 46.0 3.62e-01 92.8% 66.9%
2x8fA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.57 44.0 2.84e-01 84.1% 38.8%
1jz7A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 42.0 3.65e-01 82.6% 92.2%
3dcxA00 2.30.29.50 Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain 0.56 41.0 3.50e-01 78.3% 61.5%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.56 41.0 4.15e-01 88.4% 78.9%
4ns4A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 46.0 3.08e-01 92.8% 93.7%
6i4pA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 40.0 3.30e-01 76.8% 74.6%
2crfA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 43.0 3.54e-01 84.1% 65.6%
1e8oD00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.55 42.0 4.09e-01 82.6% 77.6%
2hjjA00 3.30.160.130 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › ykff protein like domains 0.55 40.0 4.09e-01 97.1% 84.8%
2vzsA05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 41.0 3.71e-01 84.1% 92.1%
7byjA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 41.0 3.72e-01 82.6% 70.5%
3icaB00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.54 44.0 3.26e-01 95.7% 44.2%
3dghA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 39.0 3.23e-01 76.8% 74.8%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 36.0 3.60e-01 100.0% 66.2%
5z1gB01 3.40.50.10480 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Brix domain 0.53 44.0 3.20e-01 92.8% 71.6%
5c82A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 42.0 3.17e-01 85.5% 59.4%
1qmnA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.53 41.0 3.30e-01 84.1% 70.7%
1y79101 1.10.1370.40 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.53 44.0 2.84e-01 100.0% 35.2%
1oh1A00 2.40.310.10 Mainly Beta › Beta Barrel › Staphostatins › beta-Barrel protease inhibitors 0.53 37.0 3.25e-01 73.9% 93.6%
3f2bA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 43.0 3.85e-01 88.4% 81.2%
1ye8A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 39.0 2.98e-01 81.2% 52.0%
4ka7A01 1.10.1370.40 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.52 44.0 2.81e-01 100.0% 36.3%
2k2jA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.52 39.0 3.35e-01 82.6% 68.4%
4i8oA02 3.30.160.690 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Bacterial toxin RNase RnlA/LsoA, N repeated domain 0.51 42.0 3.96e-01 100.0% 73.3%
2wkkA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 41.0 3.35e-01 95.7% 68.7%
4s1hA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.51 41.0 2.86e-01 95.7% 72.8%
3rmuA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.50 38.0 3.20e-01 87.0% 48.5%
1tluA00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.50 42.0 3.64e-01 100.0% 68.4%
ECOD (89)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4026643 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.86 80.0 7.41e-01 100.0% 85.9%
3520951 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.85 80.0 7.19e-01 100.0% 82.2%
4012540 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.85 74.0 7.23e-01 95.7% 86.7%
3333293 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.84 77.0 7.46e-01 100.0% 90.7%
3894031 330.1.1.6 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Staufen_C 0.83 71.0 6.58e-01 95.7% 75.3%
3788141 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.82 72.0 7.02e-01 95.7% 89.3%
3728854 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.82 70.0 7.22e-01 92.8% 96.9%
3730653 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.82 73.0 7.27e-01 100.0% 94.3%
3510695 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.82 72.0 6.86e-01 100.0% 82.5%
3273505 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.82 73.0 6.96e-01 97.1% 85.0%
4608418 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.81 71.0 6.63e-01 95.7% 82.4%
3730099 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.81 72.0 7.06e-01 98.6% 90.5%
3209694 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.80 73.0 6.43e-01 100.0% 70.0%
3933100 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.80 66.0 6.60e-01 92.8% 87.1%
3801624 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.80 72.0 6.31e-01 100.0% 78.0%
3707314 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 69.0 6.41e-01 98.6% 76.5%
3611339 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 72.0 6.74e-01 100.0% 85.9%
3533688 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 71.0 6.96e-01 100.0% 96.0%
3782338 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 70.0 6.28e-01 97.1% 77.4%
3487251 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 69.0 6.56e-01 100.0% 81.2%
5024241 330.2.1.5 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 0.79 69.0 6.13e-01 94.2% 77.9%
3846927 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 72.0 6.41e-01 100.0% 73.7%
3390564 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.78 67.0 5.77e-01 98.6% 61.0%
3797649 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.78 71.0 6.00e-01 100.0% 73.6%
4298652 2484.1.1.11 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ribosomal_L18p 0.77 58.0 4.79e-01 79.7% 80.8%
3479661 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.77 70.0 5.94e-01 100.0% 70.0%
3408937 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.77 70.0 6.65e-01 100.0% 90.0%
146718 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.77 67.0 5.25e-01 98.6% 47.1%
3782340 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.77 68.0 6.05e-01 97.1% 80.0%
5037621 330.2.1.0 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) 0.77 67.0 5.96e-01 94.2% 75.8%
4927872 330.2.1.5 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 0.77 66.0 5.46e-01 94.2% 60.0%
3911301 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.76 65.0 6.08e-01 100.0% 75.3%
3497120 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.76 68.0 6.10e-01 100.0% 80.0%
2010569 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.76 66.0 5.86e-01 98.6% 71.6%
3592745 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.76 68.0 5.73e-01 100.0% 60.9%
4980315 2484.1.1.21 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › BcrAD_BadFG 0.76 59.0 3.88e-01 82.6% 23.5%
4040354 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.75 68.0 6.64e-01 100.0% 94.7%
3246050 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.75 66.0 6.00e-01 100.0% 74.4%
5068822 2484.1.1.21 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › BcrAD_BadFG 0.74 57.0 5.08e-01 81.2% 58.9%
5029238 330.2.1.0 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) 0.74 67.0 5.89e-01 98.6% 77.0%
5071146 330.2.1.5 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 0.74 65.0 5.69e-01 95.7% 77.0%
4011588 4325.1.1.0 ↗ mixed a+b and a/b › YegP-like › YegP-like › YegP-like 0.74 66.0 6.46e-01 98.6% 98.7%
3284714 4325.1.1.1 ↗ mixed a+b and a/b › YegP-like › YegP-like › YegP-like › DUF1508 0.74 52.0 5.37e-01 73.9% 82.5%
4216680 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.71 65.0 5.82e-01 100.0% 76.3%
4054729 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.70 61.0 6.01e-01 97.1% 93.3%
1322782 2484.5.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RVT_connect 0.69 53.0 4.28e-01 82.6% 49.2%
4040973 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.68 57.0 5.72e-01 94.2% 94.3%
222972 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.67 56.0 5.20e-01 94.2% 76.4%
4393617 330.6.1.1 ↗ a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.66 57.0 4.65e-01 95.7% 91.5%
4638787 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.66 57.0 5.45e-01 97.1% 87.5%
5023443 330.4.1.0 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.66 54.0 5.54e-01 91.3% 96.9%
4939731 512.1.1.1 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.65 48.0 5.00e-01 91.3% 84.6%
4591449 7556.1.1.1 ↗ a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C 0.64 46.0 2.81e-01 75.4% 56.6%
3701860 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.63 47.0 4.19e-01 78.3% 65.3%
4115704 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.63 53.0 5.25e-01 97.1% 92.0%
5074419 512.1.1.1 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.62 48.0 4.95e-01 92.8% 89.2%
3514476 220.1.1.27 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_RBD 0.62 45.0 3.40e-01 78.3% 49.7%
4274345 2004.1.1.159 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M 0.62 50.0 3.63e-01 94.2% 52.4%
4128856 2004.1.1.159 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M 0.62 51.0 3.69e-01 95.7% 54.5%
3593387 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.62 44.0 3.66e-01 79.7% 40.3%
5041549 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.61 52.0 3.42e-01 92.8% 37.8%
3597605 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 47.0 3.53e-01 82.6% 55.9%
3204490 2485.1.1.30 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Phe_hydrox_dim 0.61 50.0 3.66e-01 98.6% 67.4%
3890539 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.61 42.0 4.45e-01 71.0% 85.0%
3615642 512.1.1.0 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) 0.60 48.0 4.88e-01 92.8% 95.4%
3178413 220.1.1.69 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › Meiotic_rec114 0.60 49.0 3.98e-01 89.9% 76.3%
3281348 4221.1.1.0 ↗ a+b two layers › YkuJ-like › YkuJ-like › YkuJ-like 0.59 44.0 3.88e-01 78.3% 58.0%
5046573 844.1.1.2 ↗ beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.59 50.0 3.82e-01 94.2% 90.6%
4263663 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.59 51.0 3.95e-01 100.0% 79.4%
4980820 844.1.1.2 ↗ beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.59 50.0 3.72e-01 95.7% 91.7%
4953814 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.58 41.0 4.29e-01 89.9% 86.7%
3423400 220.1.1.8 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.57 43.0 3.60e-01 82.6% 77.6%
3259121 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 46.0 3.83e-01 91.3% 72.8%
3962091 512.1.1.0 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) 0.56 45.0 4.37e-01 92.8% 80.0%
4975453 844.1.1.2 ↗ beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.56 48.0 3.68e-01 98.6% 88.2%
4950700 2485.1.1.82 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › ATP-synt_10 0.56 46.0 3.63e-01 97.1% 68.1%
5053281 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 41.0 3.38e-01 78.3% 45.6%
3479408 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.55 42.0 3.12e-01 82.6% 62.8%
3337688 241.6.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › Arp2/3 complex subunits › Arp2/3 complex subunits 0.55 45.0 3.71e-01 94.2% 92.6%
3479464 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.54 41.0 3.51e-01 82.6% 93.0%
3291683 4221.1.1.0 ↗ a+b two layers › YkuJ-like › YkuJ-like › YkuJ-like 0.54 43.0 4.00e-01 88.4% 90.0%
3300781 5.1.4.226 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DUF7899 0.54 42.0 2.96e-01 87.0% 46.6%
4819450 110.1.1.5 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › CENP-N 0.53 45.0 3.67e-01 97.1% 48.2%
3787213 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.53 45.0 3.81e-01 100.0% 56.5%
3711481 243.6.1.4 ↗ a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › Pre-PUA 0.52 42.0 3.92e-01 98.6% 70.5%
3900115 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.51 38.0 3.18e-01 82.6% 69.2%
3392597 220.1.1.66 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH 0.51 38.0 3.14e-01 82.6% 71.1%
4965528 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.50 40.0 2.94e-01 94.2% 66.2%
3587198 300.1.1.6 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › Regulator_TrmB 0.50 38.0 3.14e-01 85.5% 55.0%
D2 high residues 462-627
PDB
Domain cluster: rep: ribonuclease_III__YP_009345357__Noumeavirus__1955558__D4-208
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3n3wA00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.83 69.0 7.40e-01 96.4% 100.0%
1jfzA00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.83 70.0 7.44e-01 100.0% 100.0%
7r97A01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.82 70.0 7.41e-01 96.4% 99.3%
2qvwC06 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.81 70.0 7.26e-01 100.0% 97.4%
1o0wA01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.79 71.0 7.36e-01 98.2% 100.0%
4oogC01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.78 69.0 7.04e-01 92.8% 96.9%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.77 56.0 6.06e-01 81.9% 85.4%
1vw4501 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.76 72.0 6.29e-01 100.0% 88.5%
1vw4900 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.75 70.0 6.64e-01 100.0% 84.1%
2eb1C00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.75 71.0 7.14e-01 100.0% 100.0%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.75 63.0 6.76e-01 89.8% 100.0%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.64 25.0 2.93e-01 72.9% 48.3%
1wdhA02 1.10.720.60 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.59 29.0 3.63e-01 70.5% 76.5%
1u7gA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.55 42.0 3.23e-01 78.3% 99.2%
2nq2A00 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.53 37.0 3.07e-01 71.1% 94.8%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.52 25.0 3.22e-01 90.4% 77.9%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4070521 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.85 75.0 7.80e-01 99.4% 98.1%
4045736 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.84 75.0 7.70e-01 100.0% 97.5%
4460349 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.84 80.0 7.97e-01 100.0% 97.1%
5052864 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.84 71.0 7.57e-01 98.8% 100.0%
3838688 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.83 74.0 7.55e-01 98.8% 95.0%
4472718 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.83 70.0 6.80e-01 95.2% 80.0%
52378 171.1.1.0 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like 0.83 70.0 7.49e-01 97.0% 100.0%
4284297 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.83 70.0 7.47e-01 97.6% 100.0%
1736237 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.82 57.0 6.33e-01 73.5% 86.6%
4505265 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.82 67.0 6.70e-01 95.2% 82.4%
4237384 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.82 69.0 7.41e-01 97.6% 100.0%
4447919 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.82 73.0 7.36e-01 99.4% 93.3%
4172739 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.81 71.0 7.46e-01 95.2% 100.0%
4433400 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.80 72.0 7.19e-01 100.0% 92.4%
4506992 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.80 72.0 7.16e-01 100.0% 92.4%
3497871 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.79 62.0 6.40e-01 80.7% 100.0%
3928222 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.79 71.0 7.26e-01 99.4% 96.9%
3482033 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.79 70.0 6.76e-01 100.0% 83.2%
4022112 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.78 65.0 6.99e-01 97.6% 100.0%
3184902 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.77 59.0 6.15e-01 78.9% 89.7%
3398911 171.1.1.9 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3, Ribonucleas_3_3 0.77 72.0 5.23e-01 97.6% 51.5%
3928810 171.1.1.9 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3, Ribonucleas_3_3 0.76 72.0 6.70e-01 98.8% 96.5%
None — 0.76 72.0 6.71e-01 100.0% 95.0%
3517158 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.75 68.0 6.44e-01 95.2% 93.3%
3266933 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.75 61.0 6.28e-01 95.2% 88.1%
4598973 171.1.1.0 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like 0.75 68.0 6.16e-01 95.2% 75.8%
4389736 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.74 68.0 6.23e-01 95.2% 78.0%
1108030 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.74 68.0 6.87e-01 97.6% 96.4%
3694814 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.74 68.0 6.42e-01 97.0% 86.2%
3328773 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.74 67.0 6.37e-01 95.2% 91.6%
3934406 171.1.1.5 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › RM44_endonuclase 0.72 68.0 6.26e-01 99.4% 82.4%
3658602 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.72 65.0 6.06e-01 95.2% 79.0%
3720203 171.1.1.0 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like 0.71 60.0 5.78e-01 94.6% 80.0%
3175182 171.1.1.0 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like 0.69 59.0 6.06e-01 99.4% 93.8%
3588079 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.55 39.0 4.15e-01 89.8% 84.3%
3932290 592.2.1.2 ↗ alpha arrays › PWI domain-like › YugE-like › YugE-like › WGG 0.55 26.0 3.09e-01 70.5% 63.6%
4946590 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 34.0 3.16e-01 74.7% 48.1%
3997061 3236.1.1.1 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.52 42.0 3.20e-01 84.3% 73.6%
3264196 5067.1.1.13 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.51 30.0 3.08e-01 91.0% 58.2%
3836801 5050.1.1.15 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like 0.50 35.0 2.91e-01 74.7% 39.3%
D3 high residues 631-708
PDB
Domain cluster: representative
CATH (71)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4dkkA02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.89 77.0 7.89e-01 100.0% 95.9%
7r97A02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.81 66.0 7.03e-01 93.6% 100.0%
2lrsA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.80 68.0 7.09e-01 91.0% 100.0%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.78 68.0 7.03e-01 98.7% 100.0%
1ekzA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.78 66.0 6.68e-01 100.0% 92.1%
4bs9A05 3.30.160.660 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.77 68.0 5.91e-01 100.0% 64.9%
3tqmA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.77 62.0 5.89e-01 98.7% 74.4%
2ap1A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.74 52.0 4.25e-01 80.8% 41.0%
1xc3A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.73 46.0 4.23e-01 79.5% 48.5%
1t4lB00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.73 61.0 5.87e-01 100.0% 81.1%
2xgrA00 3.40.570.10 Alpha Beta › 3-Layer(aba) Sandwich › Extracellular Endonuclease; Chain A › Extracellular Endonuclease, subunit A 0.72 52.0 3.85e-01 75.6% 91.9%
3ll3B01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.71 54.0 3.72e-01 80.8% 26.9%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.70 58.0 5.62e-01 98.7% 81.4%
1yvuA04 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 54.0 3.89e-01 82.1% 30.8%
5nckA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.69 48.0 4.31e-01 80.8% 53.3%
6j9eJ00 3.30.160.560 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 47.0 5.08e-01 93.6% 84.8%
6izcA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.68 56.0 3.87e-01 96.2% 26.6%
2n8xA00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.68 59.0 4.69e-01 98.7% 68.1%
6kghA02 3.30.450.330 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.68 60.0 4.73e-01 96.2% 53.2%
3obaA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 48.0 4.11e-01 75.6% 95.2%
3u3gA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.67 52.0 4.28e-01 83.3% 46.4%
4ewfA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.67 54.0 3.71e-01 97.4% 25.7%
3htvA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.66 47.0 4.23e-01 87.2% 53.2%
4e19A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.66 50.0 4.21e-01 82.1% 48.1%
2vzsA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 47.0 3.99e-01 74.4% 69.9%
5df7A02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.65 56.0 3.68e-01 96.2% 23.0%
3uoaB02 2.60.40.3360 Mainly Beta › Sandwich › Immunoglobulin-like › 0.65 46.0 3.85e-01 74.4% 85.3%
2xwxA03 2.60.40.2550 Mainly Beta › Sandwich › Immunoglobulin-like › 0.65 46.0 4.27e-01 74.4% 92.9%
2nn6C00 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.65 45.0 3.05e-01 71.8% 37.0%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.65 52.0 5.20e-01 97.4% 88.6%
3bgaA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.64 46.0 4.07e-01 74.4% 94.6%
3vmnA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.64 46.0 4.04e-01 74.4% 78.4%
2w91A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 44.0 4.07e-01 74.4% 83.5%
2xepB02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.63 51.0 3.62e-01 96.2% 28.1%
1jz7A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 45.0 3.95e-01 75.6% 94.8%
5c71A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 45.0 4.22e-01 75.6% 92.7%
2a9sB00 3.90.950.20 Alpha Beta › Alpha-Beta Complex › Maf protein › CinA-like 0.62 52.0 4.19e-01 97.4% 95.2%
2vtfA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 43.0 4.14e-01 73.1% 91.2%
1nepA00 2.60.40.770 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 45.0 3.70e-01 75.6% 72.3%
1kv3A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 43.0 3.78e-01 73.1% 91.5%
2nn6E00 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.60 42.0 2.92e-01 74.4% 36.0%
4gn2A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.60 49.0 3.53e-01 91.0% 30.8%
3ia8A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.59 49.0 3.81e-01 88.5% 80.2%
3r8eA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 40.0 3.33e-01 84.6% 39.3%
2jmuA01 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.58 46.0 3.40e-01 87.2% 77.0%
5xd7A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.58 44.0 3.82e-01 83.3% 59.1%
1l3aA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.58 45.0 3.66e-01 88.5% 73.5%
2w1nA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 41.0 4.07e-01 74.4% 93.9%
1szqA02 3.30.1330.120 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › 2-methylcitrate dehydratase PrpD 0.57 42.0 3.48e-01 79.5% 98.6%
3lh4A00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 39.0 3.49e-01 73.1% 95.7%
3pddA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 40.0 3.66e-01 74.4% 81.2%
4mbrA02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 43.0 3.44e-01 84.6% 81.9%
1vemA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 45.0 4.17e-01 88.5% 94.0%
1mvpA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.56 44.0 3.93e-01 85.9% 89.3%
1rh8A00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.56 45.0 3.83e-01 93.6% 93.7%
4aefA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 41.0 3.84e-01 78.2% 85.3%
4gxbA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 43.0 4.02e-01 87.2% 88.5%
5z06B02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 39.0 3.72e-01 74.4% 89.1%
3robA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 44.0 3.81e-01 91.0% 61.1%
6bbtB01 2.60.40.3050 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 46.0 3.89e-01 96.2% 96.4%
1jzdC00 2.60.40.1250 Mainly Beta › Sandwich › Immunoglobulin-like › Thiol:disulfide interchange protein DsbD, N-terminal domain 0.54 37.0 3.32e-01 73.1% 85.6%
2gexA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 47.0 3.87e-01 98.7% 67.8%
3d3lA02 3.10.450.60 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 42.0 4.22e-01 88.5% 92.5%
3er7B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 42.0 3.67e-01 91.0% 57.7%
4hwxA00 3.30.350.10 Alpha Beta › 2-Layer Sandwich › Subtilisin Inhibitor › Subtilisin inhibitor-like 0.52 35.0 3.17e-01 70.5% 92.1%
1iz6A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 39.0 4.14e-01 96.2% 94.2%
2r39A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 39.0 3.61e-01 85.9% 87.2%
4eo3A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 45.0 3.76e-01 98.7% 66.7%
2ichA02 2.40.370.10 Mainly Beta › Beta Barrel › AttH-like fold › AttH-like domain 0.51 41.0 3.52e-01 89.7% 83.1%
3eliA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 42.0 3.54e-01 96.2% 68.8%
4j8tA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 43.0 3.74e-01 100.0% 60.9%
ECOD (92)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3246974 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.88 80.0 7.31e-01 100.0% 76.0%
3939992 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.84 75.0 6.61e-01 100.0% 68.2%
3771653 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.83 76.0 6.76e-01 100.0% 72.4%
3466381 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.82 77.0 6.76e-01 100.0% 82.7%
3797648 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.82 73.0 7.07e-01 100.0% 87.1%
3616389 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.82 73.0 7.23e-01 100.0% 92.5%
3937984 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.81 73.0 6.69e-01 100.0% 76.0%
3704401 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.81 73.0 6.36e-01 98.7% 74.8%
3797649 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.80 73.0 6.41e-01 98.7% 74.5%
4558929 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.78 65.0 6.44e-01 97.4% 86.3%
4962558 2484.1.1.22 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 0.78 58.0 4.24e-01 78.2% 37.9%
5061259 330.2.1.1 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE 0.78 69.0 6.35e-01 98.7% 75.0%
4548966 330.1.1.3 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dicer_dimer 0.78 71.0 6.02e-01 100.0% 71.2%
4036906 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.77 62.0 6.20e-01 98.7% 83.7%
3736612 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.77 68.0 6.58e-01 100.0% 87.1%
4216680 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.76 63.0 5.94e-01 98.7% 74.2%
4438684 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.76 62.0 6.07e-01 98.7% 81.0%
5024241 330.2.1.5 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 0.76 67.0 6.27e-01 97.4% 78.9%
4982298 330.2.1.1 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE 0.74 68.0 5.98e-01 98.7% 70.6%
3355734 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.74 52.0 4.69e-01 82.1% 53.7%
3810495 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.74 57.0 5.21e-01 82.1% 65.0%
4444614 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.73 65.0 6.52e-01 100.0% 96.2%
4470293 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.73 64.0 5.95e-01 94.9% 88.4%
4472716 330.1.1.3 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dicer_dimer 0.73 66.0 5.55e-01 100.0% 67.7%
3267746 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.73 63.0 6.17e-01 98.7% 87.1%
3464233 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.71 55.0 5.48e-01 82.1% 81.2%
3337433 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.71 54.0 5.39e-01 80.8% 80.0%
4023575 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.71 62.0 5.87e-01 98.7% 85.3%
3355790 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.71 54.0 4.45e-01 80.8% 47.8%
3358595 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 57.0 5.43e-01 87.2% 76.7%
4939185 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.71 62.0 5.45e-01 100.0% 80.8%
3366565 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.71 54.0 4.77e-01 80.8% 57.3%
222972 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.71 56.0 5.40e-01 92.3% 75.3%
3819047 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.70 54.0 4.48e-01 83.3% 49.3%
3351393 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.70 53.0 5.00e-01 80.8% 74.7%
3814983 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.70 56.0 5.69e-01 84.6% 89.3%
4873579 4019.1.1.3 ↗ alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.70 58.0 5.83e-01 88.5% 91.0%
3460760 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.70 54.0 4.34e-01 83.3% 49.0%
3417120 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.70 63.0 5.41e-01 98.7% 80.8%
4289288 330.6.1.1 ↗ a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.69 63.0 5.27e-01 100.0% 65.6%
3282536 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.69 61.0 6.14e-01 98.7% 97.5%
3375711 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.69 54.0 5.21e-01 85.9% 75.6%
4524129 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.68 61.0 5.73e-01 98.7% 86.3%
3960716 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.68 61.0 5.34e-01 98.7% 68.7%
4136826 7520.1.1.0 ↗ a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like 0.68 59.0 4.94e-01 97.4% 98.6%
5036880 330.1.1.35 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › LeuA_dimer 0.68 57.0 5.99e-01 94.9% 100.0%
3791028 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.68 47.0 4.01e-01 71.8% 95.2%
3830643 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.68 52.0 4.96e-01 84.6% 71.1%
4262169 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.67 59.0 5.54e-01 98.7% 80.6%
3314097 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 52.0 5.18e-01 83.3% 81.2%
5063667 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 46.0 4.12e-01 79.5% 52.4%
3962610 223.3.1.3 ↗ a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.67 57.0 4.60e-01 96.2% 51.6%
3354946 4325.1.1.0 ↗ mixed a+b and a/b › YegP-like › YegP-like › YegP-like 0.66 47.0 5.11e-01 82.1% 89.2%
5033870 11.1.4.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.66 46.0 4.72e-01 73.1% 96.0%
5043517 2484.1.1.43 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 0.66 57.0 4.19e-01 93.6% 50.0%
4957500 283.2.1.0 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.65 46.0 4.32e-01 73.1% 89.5%
3272573 4210.1.1.0 ↗ a+b two layers › WGR domain › WGR domain › WGR domain 0.65 50.0 5.16e-01 84.6% 86.7%
4269457 330.6.1.1 ↗ a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.65 58.0 4.84e-01 100.0% 72.4%
3887671 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.65 45.0 4.45e-01 73.1% 92.9%
3237969 207.1.1.52 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FBA_2 0.64 47.0 3.33e-01 76.9% 31.1%
3531848 11.1.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.64 45.0 4.41e-01 73.1% 94.1%
3196366 298.1.1.24 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 0.64 48.0 3.56e-01 78.2% 84.3%
3685150 330.6.1.1 ↗ a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.64 56.0 4.46e-01 100.0% 50.9%
3702616 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.64 55.0 4.78e-01 98.7% 83.2%
4424937 11.1.1.1150 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › InlK_D3 0.64 43.0 4.46e-01 75.6% 73.3%
4969269 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 45.0 4.15e-01 74.4% 93.0%
3460166 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 48.0 4.18e-01 80.8% 100.0%
4256745 4292.2.1.0 ↗ a+b two layers › FlaG-like › MAGUK binding stalk (MBS) domain › MAGUK binding stalk (MBS) domain 0.63 52.0 4.45e-01 92.3% 77.7%
4004011 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.62 54.0 4.91e-01 100.0% 79.1%
3271756 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.62 48.0 3.72e-01 83.3% 37.7%
3865029 4292.2.1.0 ↗ a+b two layers › FlaG-like › MAGUK binding stalk (MBS) domain › MAGUK binding stalk (MBS) domain 0.61 50.0 4.91e-01 89.7% 82.4%
3971200 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 44.0 4.17e-01 74.4% 93.3%
5082214 512.1.1.2 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_2nd 0.61 52.0 4.77e-01 97.4% 78.1%
5076544 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 44.0 4.08e-01 74.4% 88.4%
4607431 11.1.1.1150 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › InlK_D3 0.61 40.0 3.58e-01 71.8% 46.9%
3701860 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 45.0 4.19e-01 83.3% 63.2%
3629455 4.1.1.20 ↗ beta barrels › SH3 › SH3 › SH3 › BAH 0.61 42.0 3.16e-01 88.5% 29.5%
4939419 512.1.1.1 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.60 51.0 5.04e-01 98.7% 95.3%
4978348 512.1.1.0 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) 0.59 50.0 4.87e-01 94.9% 90.6%
5059888 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 42.0 4.19e-01 74.4% 92.5%
5050904 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.58 47.0 3.62e-01 87.2% 70.6%
4029311 5.1.4.73 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › RAB3GAP2_N 0.56 46.0 2.98e-01 89.7% 22.6%
3651076 2011.2.1.16 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › DUF7894 0.56 48.0 3.46e-01 96.2% 81.7%
3853362 243.3.1.2 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Cathelicidins 0.56 45.0 4.04e-01 91.0% 72.2%
4436313 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.55 47.0 4.54e-01 100.0% 94.4%
2546240 5.1.3.35 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neuraminidase 0.55 45.0 3.34e-01 92.3% 75.5%
3857554 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.54 46.0 3.00e-01 98.7% 85.8%
3587843 244.2.1.1 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.53 44.0 3.91e-01 100.0% 68.2%
3409628 11.1.1.14 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.52 40.0 3.66e-01 85.9% 90.9%
3988052 244.2.1.1 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.51 43.0 3.81e-01 100.0% 70.2%
4551342 223.1.1.0 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains 0.51 38.0 3.75e-01 83.3% 75.3%
5001433 244.2.1.1 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.50 43.0 3.69e-01 100.0% 63.7%
D4 medium residues 169-237_329-365
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jfzA00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.73 69.0 6.06e-01 100.0% 91.2%
3n3wA00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.71 65.0 5.76e-01 97.2% 93.8%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 38.0 3.69e-01 99.1% 58.2%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.51 41.0 3.52e-01 87.7% 90.4%
1bucA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 29.0 2.78e-01 89.6% 46.3%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 33.0 3.45e-01 75.5% 69.6%
5dikA00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.50 35.0 3.49e-01 91.5% 67.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4045736 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.74 70.0 6.02e-01 100.0% 88.0%
4472718 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.70 64.0 5.25e-01 97.2% 74.4%
3814902 509.1.1.1 ↗ alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.58 38.0 4.32e-01 100.0% 93.3%
4927089 3281.1.1.1 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M 0.55 44.0 2.90e-01 86.8% 51.6%
3387144 2004.1.1.159 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M 0.50 42.0 3.22e-01 95.3% 79.6%
D5 medium residues 238-328
PDB